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Aberrant CYP2D6 metabolizer phenotypes do not show increased frequency in patients undergoing ECT after antidepressant therapy

Hooman Mirzakhani, Juliët van Dormolen, Karen van der Weide, Henk-Jan Guchelaar, Martijn S. van Noorden, Jesse Swen
2015 Pharmacogenetics & Genomics  
immunoassays as assay methodologies; 1 center used HPLC and 60% (3/5) of private practice employed LCMSMS.  ...  may be useful for guiding sunitinib treatment.  ...  We favour the time sampling points at 1 and 4 h, since these time points are applicable for other TB drugs.  ... 
doi:10.1097/fpc.0000000000000167 pmid:26230381 fatcat:lniiqjkx7jhkzkuylv7ca6qfna

Deep learning in pharmacogenomics: from gene regulation to patient stratification

Alexandr A Kalinin, Gerald A Higgins, Narathip Reamaroon, Sayedmohammadreza Soroushmehr, Ari Allyn-Feuer, Ivo D Dinov, Kayvan Najarian, Brian D Athey
2018 Pharmacogenomics (London)  
We anticipate that in the future deep learning will be widely used to predict personalized drug response and optimize medication selection and dosing, using knowledge extracted from large and complex molecular  ...  This Perspective provides examples of current and future applications of deep learning in pharmacogenomics, including: (1) identification of novel regulatory variants located in noncoding domains and their  ...  For example, Kale et al. demonstrated how this type of deep model can be used for discovery and analysis of causal phenotypes from clinical time series data are capable of extraction of temporal patterns  ... 
doi:10.2217/pgs-2018-0008 pmid:29697304 fatcat:tkhmrqkevjfqxdty6ttbw33jam

SYMPOSIUM on brain and mind

1952 A M A Archives of Neurology & Psychiatry  
But to point to some of the structural and functional changes which took place in the evolution of the primates is eminently suitable as a “curtain raiser.”  ...  The arrange- ment of ganglion cells and their synaptic connections must form a relatively stable endowment, changing little with the passage of time.  ... 
pmid:14893987 fatcat:kb7yp7o4hngjrj3iuatzlsw2pq

Extraction of spatio-temporal primitives of emotional body expressions

Lars Omlor, Martin A. Giese
2007 Neurocomputing  
time-series behavior of biochemical systems.  ...  for {\em change-point analysis}, such as detecting the time at which the stimulus undergoes a change in variance; and (5) a tractable method for estimating the mutual information between a population  ... 
doi:10.1016/j.neucom.2006.10.100 fatcat:esivhljzsbcihdl5qbp756josu

Abstracts for Supplement

2010 International Journal of Infectious Diseases  
Methods: Determination of antibacterial activity in vitro: Minimum inhibitory concentrations (MICs) were determined according to CLSI(formerly NCCLs guidelines using cationadjusted Mueller-Hinton agar.  ...  Background: The Present study is undertaken to evaluate and compared the activity of the new compound YF-13-1 alone and with eight antibiotics against gram -positive and gram -negative.  ...  This paper describes the time series changes of HCC mortality in Haimen City between 1969 and 2007.  ... 
doi:10.1016/j.ijid.2010.02.001 fatcat:j5ee6nbyafh6zo4sob3vmasrtq

Abstracts from the 8th Drug Hypersensitivity Meeting (DHM)

2018 Clinical and Translational Allergy  
Our age-adjusted general population using data from the national health study confirms that viral reactivations detected, according to our insurance data base during the same period.  ...  mine antimoniate (1 case each).  ... 
doi:10.1186/s13601-018-0217-8 fatcat:7np7fs7uyrbolognek4lmcmynu

Abstracts from the International Science Symposium on HIV and Infectious Diseases (ISSHID 2019): Infectious diseases

2020 BMC Infectious Diseases  
Methods: Case series of 11 cases of early infectious syphilis in a 1year time period.  ...  ISSHID Methods: Ten millilitres of blood was obtained from 20 healthy volunteers at one time point and 20 newly-diagnosed pulmonary TB patients at three time points (before ATT, at completion of ATT and  ...  Conclusion: The study justifies the use of real time PCR for screening HCV, since false positives are possible by ELISA.  ... 
doi:10.1186/s12879-020-05038-y pmid:32429962 fatcat:k62u3w74ijd55h2frd2562a56u

Whole issue

Ελληνική Κτηνιατρική Εταιρεία
2020 Journal of the Hellenic Veterinary Medical Society  
ACKNOWLEDGMENT AKNOWLEDGEMENTS The authors would like to sincerely thank the Holstein Association of Greece for the data records from 2015 to 2018, provided by "ΙΩ" system, as well as for the flawless  ...  CONFLICT OF INTEREST The authors declare no conflict of interest.  ...  Ochi et al. ( who detected enhancement of the antimicrobial activity of dry M. oleifera leaves.  ... 
doi:10.12681/jhvms.22215 fatcat:kazv2ckcxjgbdidz2r72mxuqpq

[Microbiology / Infection / Immunity] [Genetics / Bio Resource] [Reproduction / Development / Physiology] [Disease Model] [Pharmacological and Safety Test / Anesthesia] [Facility Management] [Reproductive and Developmental Engineering / Regenerative Medicine]

2010 Experimental animals  
However, the accumulation of further data is necessary for defining normal fecal microbiota of the common marmoset. are attemp gut microbiota for the purpose of establishment of a monitoring system of  ...  gut microbiot the first step to define normal biota, we enumerated bacteria in fecal samples from four c weaning period by using culture techniques under aerobic and anaerobic conditions.  ...  A functional evaluation of ICTLAS was per information with location/time data, and by converting data to graphical indications.  ... 
doi:10.1538/expanim.59.319 fatcat:i55jl4b7avexng4y3a7i43arti

2017 ACVIM Forum Research Abstract Program

2017 Journal of Veterinary Internal Medicine  
The objective of this study was to identify clinicopathologic features, treatment and outcome of horses with eosinophilic peritonitis.  ...  Microscopic evidence of eosinophilic infiltration of abdominal organs was present (5/6). Quantitative fecal egg counts were negative in 5/6 horses.  ...  To detect differences in cortisol concentration between cosyntropin doses (1 and 5 mcg/kg) and between time points (baseline and 60-minutes), data were analyzed using a paired t-test and equivalence testing  ... 
doi:10.1111/jvim.14778 fatcat:lm3hhhjfjvgbvdfm7eib5iq7t4

Integrated Proteomics Identifies Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer's Disease [article]

Cheyenne D Hurst, Derian A Pugh, Measho H Abreha, Duc M Duong, Eric B Dammer, David A Bennett, Jeremy H Herskowitz, Nicholas T Seyfried
2022 bioRxiv   pre-print
Correlation network analysis across distinct stages of AD was used to prioritize protein modules linked to resilience.  ...  This revealed over-lapping synapse-related biology that linked NRN1-induced changes in cultured neurons with human pathways associated with AD resilience.  ...  Acknowledgements This study was supported by the following Nation Institutes of Health funding mechanisms: NINDS T32 NS061788 (DAP), NIA AG054719 (JHH), NIA AG063755, and NIA AG068024, R01AG061800 (J.H.H  ... 
doi:10.1101/2022.06.15.496285 fatcat:yx7c6yzyevfuvfcna7vn74tfwi

20th ECP

2005 Virchows Archiv  
These preliminary data showed no significant variations of the intratumoral stroma and capillaries amounts in different areas of ductal invasive breast carcinomas and also no significant correlation between  ...  The selected tumoral areas were aquired using a Nikon DN100 digital camera and a LuciaNet 1.16.2 soft.  ...  We also detected immuno-reactivity at 2 time-points posttransplantation (6 mos and 2 years) in both groups. HCV-core Ag was semiquantified from 0 to 3+ in each time-point.  ... 
doi:10.1007/s00428-005-1288-1 fatcat:25f45fdp5ffvdlo25zaqkddywm

Abstracts of the XXXIX Congress of the Spanish Society of Physiological Sciences (SECF), 18-21 September 2018, Cádiz, Spain

2018 Journal of physiology and biochemistry  
These studies will be presented in the form of plenary lectures, symposia, oral communications and posters including, for the first time, a special session for End-of-Degree projects of contrasted quality  ...  Topics cover a wide range of subjects, among them  ...  It also covers practical abilities in data mining, critical analysis and communication of research results, critical appraisal, reference managing, image analysis, and quantitative data analysis.  ... 
doi:10.1007/s13105-018-0656-7 fatcat:3w2ixa34zzbxrdbm5hy6xyag5e

Letter from the President of WFITN

2015 Interventional Neuroradiology  
Data regarding key time points of the processes, reperfusion grade, adverse events and 90 day modified Rankin scores were collected.  ...  Subjects were enrolled at 36 of 48 active centers in the US and Europe (55 IA and 53 IV).  ...  Changes of the construction address this problem.  ... 
doi:10.1177/1591019915618059 pmid:26547766 pmcid:PMC4757183 fatcat:fvlfbc5e3zac5l7gpae3qxtgzy

Program of the sixty-third annual convention

1955 American Psychologist  
Using the method of equal appearing intervals, a Social Desirability Scale was developed as a control score to detect faking. RESULTS: Reliability data: 1.  ...  Rater reliability, with the use of the scale and some experience, approaches .90. DAP Quality relates to grade-point average at 40 or better for a narrowly distributed college popu- lation.  ... 
doi:10.1037/h0049379 fatcat:4xcrjcreuncerbhmy53ixk3mfy
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