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Coupling of cerebral blood flow and oxygen metabolism is conserved for chromatic and luminance stimuli in human visual cortex
2013
NeuroImage
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The ratio of the changes in cerebral blood flow (CBF) and cerebral metabolic rate of oxygen (CMRO 2 ) during brain activation is a critical determinant of the magnitude of the blood oxygenation level dependent ...
We conclude that CBF-CMRO 2 coupling is conserved for the chromatic and luminance stimuli used, suggesting a consistent coupling for blob and inter-blob neuronal populations despite the difference in CO ...
Highlights BOLD response is sensitive to blood flow/oxygen metabolism coupling Variability of flow/metabolism coupling in human primary visual cortex was tested Chromatic and luminance stimuli to excite ...
doi:10.1016/j.neuroimage.2012.11.050
pmid:23238435
pmcid:PMC3558279
fatcat:bkein4f5i5ga3ep6daqmq5ejpu
Investigation of BOLD signal dependence on cerebral blood flow and oxygen consumption: The deoxyhemoglobin dilution model
1999
Magnetic Resonance in Medicine
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The relationship between blood oxygenation level-dependent (BOLD) MRI signals, cerebral blood flow (CBF), and oxygen consumption (CMR O 2 ) in the physiological steady state was investigated. ...
A quantitative model, based on flow-dependent dilution of metabolically generated deoxyhemoglobin, was validated by measuring BOLD signals and relative CBF simultaneously in the primary visual cortex ( ...
We are also grateful to Curtis Baker, Gareth Barnes, Joe Mandeville, and Bruce Rosen for discussion and critical reading of the manuscript. ...
doi:10.1002/(sici)1522-2594(199911)42:5<849::aid-mrm4>3.0.co;2-z
pmid:10542343
fatcat:abzq4r5vxvgxpessln6ljk7gju
Functional localization of the human color center by decreased water displacement using diffusion-weighted fMRI
2015
Brain and Behavior
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Spatial and temporal properties of DfMRI and BOLD activation were examined across regions of the visual cortex. ...
Methods: Colored and achromatic Mondrian visual stimuli were statistically contrasted to functionally localize the human color center Area V4 in neurologically intact adults. ...
Because of its sensitivity to deoxyhemoglobin concentration changes (Ogawa et al. 1990 ), which are dependent on neural activity-induced changes in cerebral blood flow, cerebral blood volume and cerebral ...
doi:10.1002/brb3.408
pmid:26664792
pmcid:PMC4667755
fatcat:inpcydkqnffwjjtwqz6p5ug27y
Feature-specific patterns of attention and functional connectivity in human visual cortex
[article]
2019
biorxiv/medrxiv
pre-print
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Attending to different features of a scene can alter the responses of neurons in early- and mid- level visual areas but the nature of this change depends on both the (top down) attentional task and the ...
One outstanding question is the spatial scale at which cortex is modulated by attention to low-level stimulus features such as shape, contrast and orientation. ...
Hence fMRI images make the assumption increased neural firing demands increased blood flow, which is taken to indicate metabolic activity in particular regions of the brain. ...
doi:10.1101/869552
fatcat:o4m4s43yhndmdnimefxqhgai34
Relating Macroscopic Measures of Brain Activity to Fast, Dynamic Neuronal Interactions
2000
Neural Computation
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PET measures blood flow distribution or regional cerebral blood flow (iCBF) in the human brain.
PET relies on the intravenous administration o f radioactive water. ...
More recently, a combination of laser Doppler flow imaging and electrode recordings has shown that there is a coupling between regional cerebral blood flow (rCBF), as measured in PET, and local field potentials ...
doi:10.1162/089976600300014737
pmid:11112256
fatcat:656c5u3mlfcozkca4dz73fdrxe
Poor glycemic control is associated with neuroretinal dysfunction in short-wavelength colour pathways in adolescents with type 1 diabetes
2010
Journal of Vision
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Poor glycemic control, as measured by hemoglobin A 1c (HbA 1c ), is a strong risk factor for DR. ...
Studies demonstrate short-wavelength cone pathway dysfunction in patients with diabetes and no clinically visible DR. ...
Chromatic VEPs Neurons in chromatic visual pathways have low chromatic thresholds and respond preferentially to chromatic stimuli of low temporal frequency since they respond in a sustained manner (Purves ...
doi:10.1167/10.15.70
fatcat:wdkzacackfezrbjk4tusfuz44i
Leigh syndrome associated with a mutation in the NDUFS7 (PSST) nuclear encoded subunit of complex I
1999
Annals of Neurology
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Leigh syndrome associated with a mutation in the NDUFS7 (PSST) nuclear encoded subunit of complex I. Annals of Neurology, 45, 787-790. ...
Leigh syndrome associated with a mutation in the NDUFS7 (PSST) nuclear encoded subunit of complex I Triepels, R.H.; van den Heuvel, L.P.; Loeffen, J.L.C.M.; Buskens, C.A.F.; Smeets, R.J.P.; Rubio Gozalbo ...
This study was supported by research grants for cardiovascular disease (9A-2 and 9A-8) from the Ministry of Health and Welfare, Japan. ...
doi:10.1002/1531-8249(199906)45:6<787::aid-ana13>3.0.co;2-6
pmid:10360771
fatcat:orer7rilszhsjd5k7xmxmqhui4
Abstracts of the 11th Annual Meeting of the Israel Society for Neuroscience
2002
Neural Plasticity
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ordered congruent, incongruent and neutral stimuli. ...
We relate these results also to the differentiated function of the anterior cingulated cortex in the verbal and motor domain. ...
not immutable in adult cerebral cortex. ...
doi:10.1155/np.2002.65
pmid:12516548
pmcid:PMC2565399
fatcat:6o7uzh2mtfawdao4mzwue32m2y
27th Annual Computational Neuroscience Meeting (CNS*2018): Part One
2018
BMC Neuroscience
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Alliance through the Initiative and Networking Fund of the Helmholtz Association and the Helmholtz Portfolio theme "Supercomputing and Modeling for the Human Brain" and the European Union Seventh Framework ...
Acknowledgements We acknowledge the Initiative and Networking Fund of the Helmholtz Association, the Helmholtz Association through the Helmholtz Portfolio Theme"Supercomputing and Modeling for the Human ...
The computational modeling of the cerebral cortex may be useful to unravel the encoding mechanism for the given stimuli in the form of effective connectivity. ...
doi:10.1186/s12868-018-0452-x
pmid:30373544
pmcid:PMC6205781
fatcat:xv7pgbp76zbdfksl545xof2vzy
Physiology of Astroglia
2018
Physiological Reviews
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Helmut Kettenmann (Berlin) and Dr. Alexandr Chvatal (Prague) for providing us with materials on glial history and to Dr. Nadia Alling for helpful discussions. ...
Pia Crine Christensen for critically reading the manuscript. ...
Compelling evidence indicates a specific role of astrocytes in neurovascular coupling and regulation of local blood flow. ...
doi:10.1152/physrev.00042.2016
pmid:29351512
fatcat:yxumfuzbpja6thxbyvljfxzlqa
Academic Press is an imprint of Elsevier
[chapter]
2009
Annual Reports in Medicinal Chemistry
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Academic Press is an imprint of Elsevier Cover photo credit: ß Corbis ...
Alcohol consumption and cognitive performance in the Framingham Heart Study. American Journal of Epidemiology, 150, 580-589. Elias, P. K., Elias, M. F., D'Agostino, R. B., Sullivan, L. ...
NIDDM and blood pressure as risk factors for poor cognitive performance: The Framingham Study. Diabetes Care, 20, 1388-1395. Elias, P. K., Elias, M. F., D'Agostino, R. B., Silbershatz, H., & Wolf, P. ...
doi:10.1016/s0065-7743(09)04435-2
fatcat:udugdegd4bhrzkgbbtzict2ed4
2017 ASCB Annual Meeting Abstracts
2017
Molecular Biology of the Cell
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The ubiquitin ligase Rsp5, the yeast homolog of human Nedd4, is a key mediator of protein quality control at the PM. ...
The goal of our research is to uncover the unappreciated role for ubiquitination and ARRDC3 in regulation of GPCR biology, not limited to PAR1 but also for other members of the GPCR superfamily. ...
dynamic pool of actin and its mode of coupling to inner-leaflet lipids is lacking. ...
doi:10.1091/mbc.e17-10-0618
pmid:29237772
pmcid:PMC5739290
fatcat:3msjrn3omzcybfanlagykayauy
Determination of a site-specific reference dose for methylmercury for fish-eating populations
2000
Toxicology and industrial health
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In cooperation with the Texas Natural Resource Conservation Commission and USEPA Region VI, Alcoa conducted a baseline risk assessment to assess potential risk to human health and the environment. ...
estimate of the traditional NOAEL, and that it is superior to the use of "average" or "grouped" exposure estimates when dose -response information is available, as is the case for the Seychelles study ...
The earliest noted critical effects were reduced sensitivity to visual stimuli of low luminance and an intention tremor upon reaching for a small object at a distance. ...
doi:10.1177/074823370001600901
pmid:11762928
fatcat:wycbdk5nfzbjjm7amw4lsgg4ki
Abstracts
1978
Kidney International
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site, (2) alteration by glucocurticoid of ionic transport at this site, thereby increasing luminal pressure in the tubule and, (3) alteration of luminal cell metabolism by glucocorticoid so as to increase ...
Morbidity and mortality for patients in advanced coma as a result of drug intoxication Is significant when treated with conservative therapy. ...
uremia did not appear for 1.0,1.2,1.8 & 2.5 yrs respectively. 5 of the 20 related grafts that did not fail had stable function for > 1 yr and 6 (all blood group A) for > 3 yrs after cessation of IT. ...
doi:10.1038/ki.1978.175
fatcat:zeudzt5hprcbxfv5e2ti7wexja
Abstracts of Current Literature
1957
Radiology
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The CO, in those tissues with a high blood flow equilibrates very rapidly with that of blood. Resting muscle and skin need at least five minutes for equilibration with the CO, of the blood. ...
In 2 cases, blood vessels in the distribution of the artery were visualized in roentgenograms representing a later phase of the study; this is probably the result of retrograde flow through anastomatic ...
doi:10.1148/68.6.879
fatcat:fb3pe7ol6rhe3jdksadrhkepji
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