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In this paper, we discuss the possibility of a detailed reconstruction of cellular dynamics during early stages of development with coupled map lattices or formalizations of Lindenmayer grammars. ... interactions take place in a space of variable structure and size. ... Acknowledgements The author wishes to thank Roberto Livi, Antonio Politi, Salvatore Di Gregorio, Ralf and Heinke Schnabel for helpful discussions. Thanks to Ralf Schnabel for ...doi:10.1016/s0304-3975(98)00155-8 fatcat:3kkbzmfpp5dqdpbgcvfncojjym
Bignone in "Coupled Maps Lattice Dynamics on a Variable Space for the Study of Development: a General Discussion on Caenorhabditis ... Elegans" present, respectively, a macroscopic cellular automata model for simulating the bioremediation of contaminated soil, and a reconstruction of living cellular dynamics with coupled maps lattices ...doi:10.1016/s0304-3975(98)00147-9 fatcat:ejnctgwd3nckjdznzd5gspssx4
Coupled map lattices dynamics on a variable space for the study of development: a general discussion on Caenorhabditis elegans. (English summary) Cellular automata (Milan, 1996). Theoret. Comput. ... On the one hand, a variety of stimulation-induced dynamical phenomena are presented; on the other hand, new data analysis tools are developed which serve as a link between theory and experiment. ...
him-4 mutations cause a novel syndrome of tissue fragility, defective cell migration and chromosome instability in Caenorhabditis elegans. ... Hemicentin tracks facilitate mechanosensory neuron anchorage to the epidermis, gliding of the developing gonad along epithelial basement membranes and germline cellularization. ... Some nematode strains used in this work were provided by the Caenorhabditis Genetics Center, which is funded by the NIH National Center for Research Resources. ...pmid:11222143 fatcat:nvq7bmv2jzapnfjjutzoxez53e
Within this framework, we review the existing empirical data on developmental changes in brain network organization across a range of experimental modalities (including structural and functional MRI, diffusion ... Synthesis: We discuss preliminary evidence and current hypotheses for how the emergence of network properties correlates with concomitant cognitive and behavioural changes associated with development. ... This review article was invited by the journal, for which the first author has been offered a small honorarium towards expenses; the article has undergone full, external peer review. ...doi:10.1111/jcpp.12365 pmid:25441756 pmcid:PMC4359009 fatcat:u5iizt6wunat5ptmbswkk4dypu
Bignone, Coupled map lattices dynamics on a variable space for the study of development: a general discussion on Caenorhabditis elegans (157-172). ... Pandu Rangan, The colored sector search tree: a dynamic data structure for ef- ficient high-dimensional nearest-foreign-neighbor queries (35—44); Danny Z. ...
To study network signaling pathways responsible for the dynamics we developed an analytic framework that constructs Temporal Sequences (TSeq), time- ordered walks of signals on graphs. ... We simulated the plausible dynamics resulting from the known C. elegans connectome using a recent model and theoretical analysis that computes the dynamics of neurobiological networks by focusing on how ... In this work we introduce a novel set of methods and analyses for this task, and apply it to the dynamics of the Caenorhabditis elegans worm connectome as an example. ...doi:10.1101/2020.05.08.085191 fatcat:lpe7edquq5azvb7bstxj6q7bny
The development of a polarized neuron relies on the selective transport of proteins to axons and dendrites. ... Using the in vivo model system Caenorhabditis elegans, we found that the highly conserved UNC-119 protein provides a link between the membrane-associated Ankyrin (UNC-44) and the microtubule-associated ... The genetics of Caenorhabditis elegans Genetics 77 :71–94. ...doi:10.7554/elife.55111 pmid:32293562 fatcat:imi3rof2a5e3dl7waobc5iezcu
For example, a mathematical description of four typical C. elegans' locomotive patterns was proposed 27 to formulate dynamics of the worm which freely crawls on an agar surface. ... Enabled by state-of-the-art technologies, a variety of external stimuli has been independently studied as a variable in the worm's environment, including temperature,    chemicals,  ...doi:10.1063/1.4908595 pmid:25759756 pmcid:PMC4336256 fatcat:lq67actk6zdd7mrzkfo2iq65lm
Importantly, this mechanism, which modestly accounts for cortical forces, does not transport dynein, which displays the same binding/unbinding dynamics as EBP-2^EB1. ... Their densities are higher on the posterior tip of the embryos, where GPR-1/2^LGN concentrate, but their durations are symmetric. ... The MosSci strain was made by the UMS 3421 Biology of Caenorhabditis elegans facility, CNRS/UCBL (Lyon, France). ...arXiv:1703.07610v2 fatcat:xov2id4llbbyrm6m355gds3mw4
TPX2 concentrations modulate the spindle architecture and lead to a concentration of MTs the poles of the X. tropicalis spindle. ... X. laevis spindles become smaller throughout development and between stage 3 and stage 8; the observed size difference can be contributed to differential regulation of kif2a. ... We thank Eric Griffis and Julie Welburn for critical reading of the manuscript and helpful comments. ...doi:10.1074/jbc.r115.638452 pmid:25957410 pmcid:PMC4498055 fatcat:wuavrudvcbcr3mkaw523x7woja
The fate maps for a variety of invertebrate embryos have been studied in detail and the specificity of pattern is remarkable (Anderson, 1973). ... The embryonic cell lineage of the nematode Caenorhabditis elegans. Developmental Biology 100, 64-119. SUMMERBELL, D., Lewis, J. H. & Wovpert, L. (1973). ...doi:10.1111/j.1469-185x.1990.tb01233.x pmid:2265224 fatcat:ntmumbksnvcxjaxl6smd22wfcu
We will discuss techniques for studying synapses in Drosophila, with a focus on the larval neuromuscular junction (NMJ), a well-established model glutamatergic synapse. ... Each synapse is a specialized junction, where the presynaptic cell assembles machinery for the release of neurotransmitter, and the postsynaptic cell assembles components to receive and integrate this ... Work in Drosophila and Caenorhabditis elegans showed that in the absence of the E3 ubiquitin ligase Highwire (Hiw; RPM-1 in C. elegans), Wnd levels increase, overactivating the Jnk pathway (Nakata et ...doi:10.1534/genetics.115.176529 pmid:26447126 pmcid:PMC4596655 fatcat:4cco2xdzvzentev3boq46dbp5y
proteins in Caenorhabditis elegans. ... Biophysical measurements, super-resolution, and electron microscopy, as well as numerical simulations of neurons as discrete, elastic rods provide evidence that a balance of torque, tension, and elasticity ... Materials and methods C. elegans strains and touch assays Request a detailed protocol Strains used in this study were derived for this study, obtained from the Caenorhabditis Genetics Center or donated ...doi:10.7554/elife.20172 pmid:28098556 pmcid:PMC5298879 fatcat:zzm6hgjabzc6xgxy5x2p2d55ty
The articles in this theme issue on 'Multi-scale analysis and modelling of collective migration' compile a range of mathematical modelling ideas and multi-scale methods for the analysis of collective migration ... Recent developments in multi-scale analysis have allowed linkage of mesoscopic to micro- and macroscopic scales, and for different biological systems. ... A.D. acknowledges generous support by the Centre for Information Services and High Performance Computing, Technische Universität Dresden. ...doi:10.1098/rstb.2019.0377 pmid:32713301 fatcat:hoa2wworrjbv3frqulmkbv7lyq
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