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F171. ALTERED DIFFUSIVITY IN THE BRAIN OF PATIENTS WITH SCHIZOPHRENIA: A DIFFUSION WEIGHTED MAGNETIC RESONANCE IMAGING STUDIES WITH PUBLIC NEUROIMAGING DATA

Young Tak Jo, Yeon Ho Joo, Harin Kim, Seung-hyun Shon, Woon Yoon, Sung Woo Joo, Jungsun Lee
2018 Schizophrenia Bulletin  
Discussion: Patients present abnormalities in networks related to stress response showing an alteration in fronto-temporal connectivity, and a poor and random modulation of these networks at rest.  ...  Current and previous findings suggest abnormal fronto-temporal connectivity that ultimately would lead to psychotic symptoms emergency in response to an environmental stressor and, even, could be related  ...  We used three separate measures of brain morphometry (voxel-based morphometry, cortical thickness, and gyrification) in a sample of healthy subjects to associate them with PGRS for schizophrenia in order  ... 
doi:10.1093/schbul/sby017.702 fatcat:3ff4sdm2yzetnk5nqhlzsegmru

F172. INDIVIDUAL PREDICTION OF RISK IN ADOLESCENT OFFSPRING OF PARENTS WITH SCHIZOPHRENIA OR BIPOLAR DISORDER: A MACHINE LEARNING NEUROIMAGING STUDY WITH A CROSS-STAGE VALIDATION

Hugo Schnack, Julia Binnewies, Nikita Setiaman, Woutje Berdowski, Neeltje van Haren, René Kahn, Manon Hillegers
2018 Schizophrenia Bulletin  
We used three separate measures of brain morphometry (voxel-based morphometry, cortical thickness, and gyrification) in a sample of healthy subjects to associate them with PGRS for schizophrenia in order  ...  MRI data were pre-processed with the CAT12 toolbox (dbm.neuro.uni-jena.de/cat12) for analysis using a) voxel-based morphometry (VBM), b) cortical thickness, and c) gyrification (calculated using the absolute  ...  Based on abundant evidence that SZ and BD are associated with structural brain abnormalities, we investigated whether MRI brain-scans can be used to detect individual risk of developing SZ or BD in adolescents  ... 
doi:10.1093/schbul/sby017.703 fatcat:nx4nbfgwnffpfg7h3vj5hh3oru

Grey-matter abnormalities in boys with Tourette syndrome: magnetic resonance imaging study using optimised voxel-based morphometry

Andrea G. Ludolph, Freimut D. Juengling, Gerhard Libal, Albert C. Ludolph, Jörg M. Fegert, Jan Kassubek
2006 British Journal of Psychiatry  
Volume-rendering magnetic resonance imaging data-sets were analysed in 14 boys with Tourette syndrome and 15 age-matched controls using optimised voxel-based morphometry.  ...  This unbiased analysis confirmed an association between striatal abnormalities and Tourette syndrome, and the hippocampal volume alterations indicate an involvement of temporolimbic pathways of the CSTC  ...  P., et al et al (2004) (2004) Voxel-based morphometry in adolescents with Voxel-based morphometry in adolescents with bipolar disorder: first results. bipolar disorder: first results.  ... 
doi:10.1192/bjp.bp.105.008813 pmid:16648537 fatcat:5gvyyixdjzgotfgxdjevs352d4

Combined analysis of grey matter voxel-based morphometry and white matter tract-based spatial statistics in late-life bipolar disorder

Sven Haller
2011 Journal of Psychiatry & Neuroscience  
We conducted a voxel-based morphometry (VBM) analysis and a tract-based spatial statistics (TBSS) analysis to assess fractional anisotropy and longitudinal, radial and mean diffusivity derived by diffusion  ...  Results: We included 19 patients with bipolar disorder and 47 controls in our study.  ...  Acknowledgements: We thank all patients and controls for participating in this study.  ... 
doi:10.1503/jpn.100140 pmid:21284917 pmcid:PMC3201993 fatcat:nqyvgejo2fduflw2u6h7mxeti4

Grey matter abnormalities in Brazilians with first-episode psychosis

Maristela S. Schaufelberger, Fabio L. S. Duran, Julia M. Lappin, Marcia Scazufca, Edson Amaro, Claudia C. Leite, Claudio C. De Castro, Robin M. Murray, Philip K. McGuire, Paulo R. Menezes, Geraldo F. Busatto
2007 British Journal of Psychiatry  
psychosis and controls in Brazil Method Magnetic resonance imaging using voxel-based morphometry was performed on 122 people with first-episode psychosis and 94 controls Results There were significant  ...  decreases in grey matter in the left superior temporal and inferior prefrontal cortices, insula bilaterally and the right hippocampal region in first-episode psychosis (P<0.05, corrected for multiple  ...  Ferraz Alves for helpful discussions and Neeltje van Haren for for helpful discussions and Neeltje van Haren for helping with assessment of inter-scanner reliability. helping with assessment of inter-scanner  ... 
doi:10.1192/bjp.191.51.s117 pmid:18055927 fatcat:e5666iipbzcsji4d427jrbwzoi

No change to grey and white matter volumes in bipolar I disorder patients

Harald Scherk, Claudia Kemmer, Juliana Usher, Wolfgang Reith, Peter Falkai, Oliver Gruber
2008 European Archives of Psychiatry and Clinical Neuroscience  
The aim of this study was to investigate grey and white matter volumes in a large sample of patients with bipolar I disorder.  ...  Hence, there is no clear evidence so far for core regions of cortical or subcortical structural abnormalities in bipolar disorder.  ...  Voxel-based morphometry (VBM) is a new method which allows the investigation of structural MRI of the brain that is free from hypotheses and user-bias [2] .  ... 
doi:10.1007/s00406-007-0801-8 pmid:18347837 pmcid:PMC3085759 fatcat:smdevfexkvanbjyljggo5gym3a

Brain structure in women at risk of postpartum psychosis: an MRI study

Montserrat Fusté, Astrid Pauls, Amanda Worker, Antje A. T. S Reinders, Andrew Simmons, Steven C. R. Williams, Josep M. Haro, Kate Hazelgrove, Susan Pawlby, Susan Conroy, Costanza Vecchio, Gertrude Seneviratne (+3 others)
2017 Translational Psychiatry  
We obtained T1-weighted MRI scans at 3T and examined regional gray matter volumes with voxel-based morphometry and cortical thickness and surface area with Freesurfer.  ...  The risk of PP is very high in women with a history of bipolar affective disorder or schizoaffective disorder.  ...  Acknowledgements The research was supported by a NARSAD Independent Investigator Award to Dr P. Dazzan  ... 
doi:10.1038/s41398-017-0003-8 pmid:29249808 pmcid:PMC5802701 fatcat:zok5ytfdtrf2tgq7y4kikevweu

Regional volume deviations of brain structure in schizophrenia and psychotic bipolar disorder

Colm McDonald, Ed Bullmore, Pak Sham, Xavier Chitnis, John Suckling, James Maccabe, Muriel Walshe, Robin M. Murray
2005 British Journal of Psychiatry  
Aims To assess volumetric abnormalities of grey and white matter throughout the entire brain in individuals with schizophrenia or with bipolar disorder compared with the same control group.  ...  It is unclear whether schizophrenia and psychotic bipolar disorder are associated with similar deviations of brain morphometry.  ...  ACKNOWLEDGEMENT ACKNOWLEDGEMENT C.McD. and E.B. were supported by the Wellcome C.McD. and E.B. were supported by the Wellcome Trust. Trust.  ... 
doi:10.1192/bjp.186.5.369 pmid:15863740 fatcat:5syq5ydu2jhvhoyuoswypsg6ae

Insula sub-regions across the psychosis spectrum: morphology and clinical correlates

Julia M. Sheffield, Anna S. Huang, Baxter P. Rogers, Jennifer Urbano Blackford, Stephan Heckers, Neil D. Woodward
2021 Translational Psychiatry  
Morphological abnormalities were limited to lower gyrification in psychotic disorders, which was specific to schizophrenia and associated with cognitive ability.  ...  a large group of adults with a psychotic disorder (schizophrenia spectrum, psychotic bipolar disorder) and a community-ascertained cohort of psychosis-spectrum youth (age 8–21).  ...  Insula volume and surface features Brain volumes and cortical surface features (i.e., thickness, gyrification, sulcal depth) were quantified using voxel-based morphometry (VBM) and surface-based morphometry  ... 
doi:10.1038/s41398-021-01461-0 pmid:34088895 fatcat:vrxpxxbf2zhkrj5ddwctmwavbm

Morphometry and gyrification in bipolar disorder and schizophrenia: a comparative MRI study

Nuno Madeira, João Valente Duarte, Ricardo Martins, Gabriel Nascimento Costa, António Macedo, Miguel Castelo-Branco
2020 NeuroImage: Clinical  
/grey matter volume (voxel-based morphometry - VBM).  ...  Data analyses were performed with CAT12/SPM12 applying general linear models for four morphometric measures: gyrification and cortical thickness (surface-based morphometry), and whole-brain grey matter  ...  We are also very grateful to Carlos Ferreira and Sónia Afonso for the help with MRI setup and scanning, and Licínio Craveiro for English language reviewing and observant comments.  ... 
doi:10.1016/j.nicl.2020.102220 pmid:32146321 pmcid:PMC7063231 fatcat:rgyzxu7dsvhl7cpfojqzhq5eiy

Brain morphology and neurological soft signs in adolescents with first-episode psychosis

Joost Janssen, Angeles Diaz-Caneja, Santiago Reig, Igor Bombín, María Mayoral, Mara Parellada, Montserrat Graell, Dolores Moreno, Arantzazu Zabala, Veronica García Vazquez, Manuel Desco, Celso Arango
2009 British Journal of Psychiatry  
Volumes were assessed using voxel-based morphometry and through segmentation of anatomical structures.  ...  Aims To examine whether increased severity of neurological soft signs was associated with decreased brain volumes in adolescents with first-episode psychosis.  ...  Acknowledgements The authors thank the participants and their families.  ... 
doi:10.1192/bjp.bp.108.052738 pmid:19721112 fatcat:cbzapjutuzc6fjczzttzmr4rhe

Comparison of Cerebellar Grey Matter Alterations in Bipolar and Cerebellar Patients: Evidence from Voxel-Based Analysis

Michela Lupo, Giusy Olivito, Andrea Gragnani, Marco Saettoni, Libera Siciliano, Corinna Pancheri, Matteo Panfili, Marco Bozzali, Roberto Delle Chiaie, Maria Leggio
2021 International Journal of Molecular Sciences  
A voxel-based morphometry analysis was used to show similarities and differences in cerebellar grey matter (GM) loss between the groups.  ...  cerebellar role in the cognitive and mood dysregulation symptoms that characterize bipolar disorder.  ...  Informed Consent Statement: Informed consent was obtained from all subjects involved in the study. Data Availability Statement: Study data will be shared upon request.  ... 
doi:10.3390/ijms22073511 pmid:33805296 fatcat:fi72vpeehzf6bkfu76x2jmpjt4

Structural MRI Brain Alterations in Borderline Personality Disorder and Bipolar Disorder

Jack B Ding, Kevin Hu
2021 Cureus  
Bipolar disorder (BD) and borderline personality disorder (BPD) share many behavioral features, such as periods of marked affective lability and instability.  ...  We performed a literature review on the structural MRI features of both disorders and compared the findings.  ...  There was no significant differences in cortical thickness [17] software Schienle Voxel-based morphometry to measure et al., Patients with BPD exhibited increased GM volume in the laterobasal amygdala.  ... 
doi:10.7759/cureus.16425 fatcat:dkn6uzdgsvfpnnemll5vivxsqe

Brain Mapping Using Neuroimaging

Woo-Suk Tae, Shin-Hyuk Kang, Byung-Joo Ham, Byung-Jo Kim, Sung-Bom Pyun
2016 Applied Microscopy  
methods, such as voxel-based morphometry, cortical thickness analysis, local gyrification index, and shape analysis for structural imaging.  ...  Tract-Based Spatial Statistics, TRActs Constrained by UnderLying Anatomy for diffusion MRI, and independent component analysis for fMRI also will also be introduced.  ...  of brain volumetry, voxel-based morphometry (VBM), cortical thickness analysis, shape analysis, and the local gyrification index (LGI) (Fig. 2) .  ... 
doi:10.9729/am.2016.46.4.179 fatcat:erx2aerd3veard77idz5lmcori

Neural correlates of hallucinations in bipolar disorder

Maila de C. Neves, Dante G. Duarte, Maicon R. Albuquerque, Rodrigo Nicolato, Fernando S. Neves, Fábio L. de Souza-Duran, Geraldo Busatto, Humberto Corrêa
2016 Revista Brasileira de Psiquiatria  
Voxel based morphometry (VBM) was used to compare patients with and without a lifetime history of hallucinations.  ...  The aim of the present study was to investigate the structural correlates of a history of hallucinations in a sample of euthymic patients with bipolar I disorder (BD-I).  ...  Acknowledgements This study received financial support from the Deanship of Research at Universidade Federal de Minas Gerais, Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), and Fundac  ... 
doi:10.1590/1516-4446-2014-1640 pmid:26785108 fatcat:fqszsvjvn5cftnzu7drvc3imxm
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