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Plasmodium falciparum immunodominant IgG epitopes in subclinical malaria [article]

Isabel G. Azcarate, Patricia Marin-Garcia, Paloma Abad, Susana Perez-Benavente, Estela Paz-Artal, Pedro A Reche, Julius N. Fobil, Jose M. Rubio, Amalia Diez, Antonio Puyet, Jose M. Bautista
2019 bioRxiv   pre-print
For further epitope mapping, peptide microarrays designed to cover their sequences were probed with a set of 38 sera samples from adult individuals of an endemic malaria region in Ghana.  ...  We performed IgG-immunomics to screen for P. falciparum antigens and to identify epitopes associated with exposure and clinical disease.  ...  We also thank to Maria L. Ruperez, Edwige Gaba and Juana Garrido and all the Breman-Asikuma Community of the Sisters of Charity of St.  ... 
doi:10.1101/792499 fatcat:wjy55x7yr5hbxk5vn7h5zpocmi

Antenatal HIV-1 RNA load and timing of mother to child transmission; a nested case-control study in a resource poor setting

Kerina Duri, Felicity Z Gumbo, Knut I Kristiansen, Nyaradzi E Kurewa, Munyaradzi P Mapingure, Simbarashe Rusakaniko, Mike Z Chirenje, Fredrik Muller, Babill Stray-Pedersen
2010 Virology Journal  
We also wish to thank collaborating institutions for capacity building and technology transfer: the University of Zimbabwe, Letten Foundation Research Centre, University of Oslo, and Oslo University Rikishospitalet  ...  Special mention goes to the Letten Foundation and Professor Letten herself for funding the study.  ...  J Virol 2006; 80(15):7427-7438. (17) Hooper E: Experimental oral polio vaccines and acquired immune deficiency syndrome.  ... 
doi:10.1186/1743-422x-7-176 pmid:20678190 pmcid:PMC2919474 fatcat:irclkdjd7jchfk5kvduvx53f7u

34th Annual Meeting & Pre-Conference Programs of the Society for Immunotherapy of Cancer (SITC 2019): part 1

2019 Journal for ImmunoTherapy of Cancer  
Results Preliminary cohort of 10 patients includes 4 with recurrence at a median of 2.4 years and 6 with no recurrence at a median of 12 years post-LT.  ...  We evaluated a preliminary cohort of 10 patients using qmIF, excluding patients with viral hepatitis. FFPE tumor sections were pre-selected by a GI pathologist.  ...  Ethics Approval The study was approved by the COH Institutional Review Board (IRB) and Office of Human Subjects Protection.  ... 
doi:10.1186/s40425-019-0763-1 pmid:31694725 pmcid:PMC6833189 fatcat:y2lipm7rwrav3jdwdo3um27qhu

Visceral Leishmaniasis (Kala-Azar) Outbreak in Somali Refugees and Kenyan Shepherds, Kenya

Gunter Boussery
2001 Emerging Infectious Diseases  
Bouchez is a scientist at Institut Pasteur, Paris, France. Her research focuses on Bordetella spp. diversity and evolution in the context of vaccination.  ...  Ai is a clinical resident at Huashan Hospital affiliated to Fudan University.  ...  Indeed, upon treatment with PK, dromedary PrP res preserved the N terminal 12B2 and SAF32 mAb epitopes, whereas classical scrapie lost the SAF32 mAb epitope while preserving the 12B2 mAb epitope, and BSE  ... 
doi:10.3201/eid0703.010346 fatcat:5l7m54kanbcopmto35k4hqq23a

Emerging Infectious Diseases [chapter]

2012 Atlas of Human Infectious Diseases  
Acknowledgments We thank the project staff at the antenatal clinic, labor ward, counselors, laboratory technicians, and computer data entry staff for assisting in many ways to realize this work.  ...  She is currently working on a reporter system to classify antimicrobial activity.  ...  Sequences were assembled from the resultant electropherograms with the STADEN suite of computer programs (12) .  ... 
doi:10.1002/9781444354690.ch1 fatcat:4p7idisgunbnbdodpts77nnelq

Emerging Infectious Diseases

2015 Wilderness & environmental medicine (Print)  
Acknowledgments We thank the project staff at the antenatal clinic, labor ward, counselors, laboratory technicians, and computer data entry staff for assisting in many ways to realize this work.  ...  She is currently working on a reporter system to classify antimicrobial activity.  ...  Sequences were assembled from the resultant electropherograms with the STADEN suite of computer programs (12) .  ... 
doi:10.1016/j.wem.2015.06.004 fatcat:x2divpclkvdwbke3fqqvsmraya

Clinical Sciences and Therapeutics for health

Natalia Neophytou, Kerith Aginsky, Natalie Benjamin
2017 Southern African Journal of Infectious Diseases  
Further functional analyses are required, but this finding enforces the need to look beyond the exome when trying to identify causal mutations for a subset of Mendelian diseases.  ...  Keratolytic Winter Erythema (KWE) is a rare skin disorder of unknown aetiology that is characterized by erythema, keratin layer thickening and centrifugal skin peeling of the palms and soles, especially  ...  Computational and experimental mapping identified bNAbs targeting the MPER, CD4bs, gp120-gp41 interface, glycan-V2, and glycan-V3 epitopes with the latter two specificities most common.  ... 
doi:10.4102/sajid.v32i2.50 fatcat:rg67lmnm7rh4hairc5llrzye6q

Turning the Tide on HIV: 23rdAnnual Canadian Conference on HIV/AIDS Research

2014 Canadian Journal of Infectious Diseases and Medical Microbiology  
Here we utilized a global proteomics approach, coupled to multivariate computational modeling, to better understand the impact and downstream consequences of of BV-related inflammation upon the mucosal  ...  We has recently utilized human VZV as a vaccine vector in the SIV macaque model of HIV and demonstrated that approximately a third of cynomolgus macaques vaccinated once with VZV-SIV constructs and challenged  ...  BACkGROUND: Recent attention has been given to the role of PTSD and other trauma related disorders as a risk factor for HIV infection.  ... 
doi:10.1155/2014/148567 fatcat:vsfzrkkh7fd6hezjlreppkb7fm

Abstracts of FIS/HIS 2016 – Poster Presentations

2016 Journal of Hospital Infection  
Aim(s)/Objective(s): The aim of this study was to detect the frequency of different bacterial isolates and their antibiotic susceptibility pattern from patients admitted to adult ICU in a 5 year period  ...  from January 2008 to December 2012 at Nizwa hospital, Oman.  ...  We tested whether minimal epitope-insert adenoviral vectors (called "minigene vectors"), can provide effective, targeted vaccine responses against a range of epitopes.  ... 
doi:10.1016/s0195-6701(16)30516-3 fatcat:32giivqqa5cg7ko33gfqg6emim

The evolution of the anti-HIV envelope antibody response

Katie McFaul, William Peter Kelleher, St Stephen's AIDS Trust
I screened sera from a cohort of highly exposed seronegative men who have sex with men with a yeast displayed HIV-1 gp140 envelope antigen fragment library to map discrete epitopes responsible for anti-HIV  ...  Stratification of cohort according to risk region of acquisition of HIV-1 infection revealed no significant changes in the distribution of envelope epitope detected.  ...  To date, very few vaccine trials have progressed to efficacy in human stage.  ... 
doi:10.25560/87561 fatcat:kla7au43afckfodvhcnrwgxm5a

American Association of Neuropathologists, Inc.: Abstracts of the 85thAnnual Meeting June 11-14, 2009 San Antonio, Texas

2009 Journal of Neuropathology and Experimental Neurology  
epitope, and 125Ilabeled protein A.  ...  PCR analysis of CSF was negative for DNA from varicella zoster virus, human herpes virus, cytomegalovirus, mycobacterium tuberculosis and JC virus.  ... 
doi:10.1097/nen.0b013e3181a407ee fatcat:rhq7jxnojfcqrncfhdrqgytzqa

24(th) Annual Canadian Conference on HIV/AIDS Research/24(e) Congrès Annuel Canadien de Recherche sur le VIH/sida CAHR Committees / Comités de l'ACRV

2015 Canadian Journal of Infectious Diseases and Medical Microbiology  
and maintain memory, all of which contribute to a global impairment of the immune humoral compartment.  ...  RESULTS: Upon binding IL-7, surface CD127 is rapidly phosphorylated and internalized while activation of the JAK/STAT5 pathway induces production of CIS proteins.  ...  EPH68,EPH69,EPH70 Deshiere A . . . . . . . . . . . . . . . . . . . . . . .  ... 
pmid:26015799 pmcid:PMC4427862 fatcat:hjukjvydzna4pnrq2uzc2hbooi

44th Annual Congress of the Canadian Neurological Sciences Federation

2009 Canadian Journal of Neurological Sciences  
Method: We report a case of opsoclonus myoclonus syndrome (OMS) associated with a cytomegalovirus (CMV) mononucleosis.  ...  Specific Dystonia of Foot Upon Walking.  ...  Computed tomography on POD 5 demonstrated no change in the size of the collective aneurysm-thrombus mass.  ... 
doi:10.1017/s0317167100008799 fatcat:p5tedzaxbnczpbm5fashrtpxyi

Viral gastroenteritis in children with and without HIV infection in Blantyre, Malawi

Nigel Andrew Cunliffe
Diarrhoeal disease is a leading cause of childhood morbidity and mortality worldwide. A large part of this disease burdenis attributed to enteric viruses.  ...  A second major objective of this work was to examinethe extentofrotavirus strain diversity in Blantyre.  ...  ACKNOWLEDGMENTS Nigel Cunliffe is the recipient of a Wellcome Trust Research Training Fellowship in Clinical Tropical Medicine (grant 049485/Z/96).  ... 
doi:10.17638/03146565 fatcat:vzdk22v4pfapvify73yskaaf7a