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Effects of cerebral ischemia on human neurovascular coupling, CO2 reactivity, and dynamic cerebral autoregulation

Angela S. M. Salinet, Thompson G. Robinson, Ronney B. Panerai
2015 Journal of applied physiology  
CBF velocity in the middle cerebral artery (MCA) (CBFv, transcranial Doppler), blood pressure (BP, Finometer), and end-tidal PCO 2 (PETCO 2 , infrared capnography) were recorded during a 1-min passive  ...  Cerebral blood flow (CBF) regulation can be impaired in acute ischemic stroke but the combined effects of dynamic cerebral autoregulation (CA), CO 2 cerebrovascular reactivity (CVR), and neurovascular  ...  CBFv, cerebral blood flow velocity; BP, mean arterial blood pressure; PETCO 2 , end-tidal PCO2; LF, low frequency; Mx, mean velocity index.  ... 
doi:10.1152/japplphysiol.00620.2014 pmid:25593216 fatcat:ceqfcwbqovcmndpjyc72raeldi

Neuroprotective measures in children with traumatic brain injury

Shruti Agrawal
2016 World Journal of Critical Care Medicine  
Standard neuroprotective measures are based on management of intracranial pressure (ICP) and cerebral perfusion pressure (CPP) to optimize the cerebral blood flow and oxygenation, with the intention to  ...  We discuss the often limited evidence for these therapeutic interventions in children, extrapolation of data from adults, and current recommendation from paediatric guidelines.  ...  Transcranial Doppler ultrasonography Transcranial Doppler ultrasonography (TCD) is a noninvasive method that measures the flow velocity in middle cerebral artery [95] .  ... 
doi:10.5492/wjccm.v5.i1.36 pmid:26855892 pmcid:PMC4733454 fatcat:ale5qu6bgjhprpnajtt6ifem4y


2013 Cerebrovascular Diseases  
, conventional transcranial Doppler sonography (TCD) allows blood flow velocities to be recorded from basal cerebral arteries through the intact skull.  ...  Cerebral autoregulation is an important physiological mechanism that assists in maintaining cerebral blood flow relatively constant in the face of constantly changing blood pressure.  ...  Data extraction was based on ultrasound variables, patient characteristics, and outcome variables (rate of intracranial hemorrhages and arterial recanalization). Informed consent forms were applied.  ... 
doi:10.1159/000351748 pmid:23712294 fatcat:kuw65edukrgkfdsnvwgsbj2r4m

Dynamic brain-body coupling of breath-by-breath O2-CO2 exchange ratio with resting state cerebral hemodynamic fluctuations

Suk-Tak Chan, Karleyton C Evans, Tian-Yue Song, Juliette Selb, Andre van der Kouwe, Bruce R Rosen, Yong-Ping Zheng, Andrew C Ahn, Kenneth K Kwong
2020 PLoS ONE  
We used transcranial Doppler sonography to evaluate CHF by measuring the changes in cerebral blood flow velocity (ΔCBFv) in bilateral middle cerebral arteries.  ...  is defined as the ratio of the change in the partial pressure of oxygen (ΔPO2) to that of carbon dioxide (ΔPCO2) between end inspiration and end expiration.  ...  Acknowledgments Our team appreciates the expertise physiologic advice provided by Dr. Robert Banzett. Author Contributions Conceptualization: Suk-tak Chan, Kenneth K. Kwong.  ... 
doi:10.1371/journal.pone.0238946 pmid:32956397 pmcid:PMC7505589 fatcat:27oa64w23ractlgm22asvjo2pm

Laminar microvascular transit time distribution in the mouse somatosensory cortex revealed by Dynamic Contrast Optical Coherence Tomography

Conrad W. Merkle, Vivek J. Srinivasan
2016 NeuroImage  
The transit time distribution of blood through the cerebral microvasculature both constrains oxygen delivery and governs the kinetics of neuroimaging signals such as blood-oxygen-leveldependent functional  ...  Laminar trends were identified, with earlier transit times and less heterogeneity in the middle cortical layers.  ...  Acknowledgments We acknowledge support from the National Institutes of Health (R00NS067050, R01NS094681, P30AG010129) and the Glaucoma Research Foundation Catalyst for a Cure.  ... 
doi:10.1016/j.neuroimage.2015.10.017 pmid:26477654 pmcid:PMC4691378 fatcat:px6d7cipy5hs3nigr7cvdfli5e


2010 Cerebrovascular Diseases  
latest method superior for the examination of cerebral circulation.  ...  Transcranial Dopplerography (TCD) is well known technique based on the recording of the ultrasound waves reflection from cerebral blood flow with pulse-wave Doppler technology to record velocities in intracranial  ...  Blood flow velocity of middle cerebral artery (MCA) was monitored on TCD and ABP were recorded in right femoral artery to calculate CCP.  ... 
doi:10.1159/000315331 fatcat:hr65yin5bjhedcujexbhd7ygfm

13th Meeting of the European Society of Neurosonology and Cerebral Hemodynamics. 5th National Congress of the Italian Society of Neurosonology and Cerebral Hemodynamics. Genova, Italy, May 10–13, 2008 (Pages 39–68)

2008 Cerebrovascular Diseases  
We couldn't perform cerebral MRI because of presence of abdominal vascular clips.  ...  Journal of Neuroimaging, 1999, V9, N3.141-149.) Results: The relationship between body tilt angle and FV was characterized by two straight lines: one with constant and the other-with rising FV.  ...  Impact of Middle Cerebral Artery Stenosis on Neurovascular Coupling in Posterior Cerebral Artery Non-Invasive Vascular Neuroimaging in Acute Ischemic New Diagnostic Criteria of Middle Cerebral Artery  ... 
doi:10.1159/000131906 fatcat:t4kxrvc5j5g5te3q6yxner35xy

42nd Annual Congress Canadian Neurological Sciences Federation

2007 Canadian Journal of Neurological Sciences  
To generate CVR maps a recently introduced noninvasive blood oxygen level-dependent magnetic resonance imaging-based method was applied during rapid manipulation of end-tidal PCO2.  ...  The left middle cerebral artery was transiently occluded for 30 minutes in male C57 Black 6 mice.  ...  The Canadian Journal of Neurological Sciences (CJNS) is always looking for talented and skilled reviewers to submit timely and high quality reviews of manuscripts.  ... 
doi:10.1017/s0317167100017054 fatcat:7kj4qzqunnhabhfrthsyx3wpje

48th Annual Congress of the Canadian Neurological Sciences Federation

2013 Canadian Journal of Neurological Sciences  
Middle cerebral artery blood flow velocity (MCAv), heart rate (HR), blood pressure (BP) and intracranial pressure (ICP) were recorded whenever available. CvR index was calculated as ∆ MCAv / Δ PCO2.  ...  a simple 7 mm middle cerebral artery aneurysm.  ...  Results: CIPN occurred in children at a frequency of 18.8% (29/154) for ALL; 9.4% (3/32) for lymphoma; 17.9% (5/28) for Wilms tumor; and 23.7% (9/38) for brain tumor.  ... 
doi:10.1017/s031716710001708x fatcat:m2kbjrxv2bh6xhyw3f45pvye5e

ESICM LIVES 2021: Part 1

2021 Intensive Care Medicine Experimental  
However, the amount of protein received by the HPE group was significantly higher than that received by the control group (p < 0.0001).  ...  We randomized mechanically ventilated patients expected to stay in the intensive care unit (ICU) for at least 4 days.  ...  The end-tidal-to-arterial PCO2 ratio was lower in non-survivors thanin survivors (p < 0.001).  ... 
doi:10.1186/s40635-021-00413-8 pmid:34633565 fatcat:ky75zcwr45btlchccmwuwn77nm

3 Invited speakers abstracts

2017 Journal of Perinatal Medicine  
Eclampsia remains one of the five major causes of maternal mortality in developing countries.  ...  This is a case of a 23years old unbooked primigravida who is unsure of her date but said to be nine month Amenorrhoec.  ...  Avoiding obesity, appropriate weight gain during pregnancy, a nd the promotion of breast-feeding are essential.  ... 
doi:10.1515/jpm-2017-2007 fatcat:3qfniipguvcdbjoxs4fsj7r37a

Abstracts for the 13th Turkish Neuroscience Congress April 30th 2015 to May 3rd 2015, Konya, Turkey

2015 Anatomy (International Journal of Experimental and Clinical Anatomy)  
The visualization of living ultra-micro-structures is a great accomplishment, a culmination of centuries of scientific endeavors.In contrast, the phylogenic aspects of vascular, neoplastic, degenerative  ...  predilection sites of these diseases, which affect certain compartments of the CNS, in relation to their phylogenic, ontogenic, histogenetic and angiogenic order.  ...  The understanding of the physiologic functions of pericytes is imperative not only for understanding the dynamics of cerebral blood flow at the microcirculatory level but also for alleviating the pathologic  ... 
doi:10.2399/ana.15.001s fatcat:cc6uyz2r2ve2fcomz3f5ptr5re

Proceedings of Réanimation 2018, the French Intensive Care Society International Congress

2018 Annals of Intensive Care  
Demographic data, physiologic data (including pH and partial pressure of carbon dioxide in arterial blood [PaCO2]) before ECCO2R starting, and at day 1 were recorded.  ...  Introduction: In septic shock there are physiological changes with an increase in the volume of distribution, with implications for pharmacokinetics of antibiotics that make recommended doses potentially  ...  For the 2nd, 3rd, 4th and 5th day, blood samples were taken before the infusion (T0), at the end (T1) and 30 min after the end of it (T2). Results: 18 burned patients were included.  ... 
doi:10.1186/s13613-017-0345-7 pmid:29404789 pmcid:PMC5799093 fatcat:h3ovufvuszcr5kofw4vdjj33ai

The pathophysiology of hypoxic ischemic brain injury after cardiac arrest

Mypinder Myp Sekhon
The results identified distinct physiologic phenotypes in that diffusion limitation of oxygen delivery accounted for the predominant mechanism of brain hypoxia after resuscitation in half of the cohort  ...  between the physiologic determinants of cerebral oxygen delivery and brain tissue oxygenation in hypoxic ischemic brain injury.  ...  For example, a correlational coefficient between MAP and mean flow velocity of the middle cerebral artery via transcranial Figure 2 . 2 14 .  ... 
doi:10.14288/1.0395938 fatcat:eczqeb5ibzdn7bv4ugbosdtxn4

Proceedings of Réanimation 2017, the French Intensive Care Society International Congress

Chtara Kamilia, Kais Regaieg, Najeh Baccouch, Hedi Chelly, Mabrouk Bahloul, Mounir Bouaziz, Ali Jendoubi, Ahmed Abbes, Houda Belhaouane, Oussama Nasri, Layla Jenzri, Salma Ghedira (+1089 others)
2017 Annals of Intensive Care  
For included patients, skin levy, blood cultures, urine and sputum cultures were drawn during fever or clinical features of sepsis.  ...  Five preventive measures were held: hand hygiene, the elevation of the head of the bed at 30°-45°, the daily lifting of sedation, oral decontamination with chlorhexidine and control cuff pressure of the  ...  The intra-and interoperator reproducibility was good to excellent for the systolic and mean velocities of the hepatic artery, portal vein diameter and the PVBF.  ... 
doi:10.1186/s13613-016-0224-7 fatcat:2iumv76ivzdszafcy6hbqkd7um
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