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Optimized weighting for Fourier rebinning of three-dimensional time-of-Flight PET data to non-time-of-flight

Sangtae Ahn, Sanghee Cho, Quanzheng Li, R.M. Leahy
2009 2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)  
Time-of-flight (TOF) PET scanners provide the potential for significantly improved signal-to-noise ratio (SNR) and lesion detectability in clinical PET.  ...  In this paper we address the question of optimal rebinning in order to make full use of TOF information and consequently to maximize image quality.  ...  Townsend of the Singapore Bioimaging Consortium and Drs. M. Casey, V. Panin and B. Jakoby of Siemens Medical Solutions for their assistance with analysis of the phantom data.  ... 
doi:10.1109/nssmic.2009.5401593 fatcat:7jvasxsj6ra6tdo272ylqbhrbe

Optimal Rebinning of Time-of-Flight PET Data

Sangtae Ahn, Sanghee Cho, Quanzheng Li, Yanguang Lin, R. M. Leahy
2011 IEEE Transactions on Medical Imaging  
Time-of-flight (TOF) positron emission tomography (PET) scanners offer the potential for significantly improved signal-to-noise ratio (SNR) and lesion detectability in clinical PET.  ...  In this paper we address the question of optimal rebinning in order to make full use of TOF information.  ...  Jakoby of Siemens Medical Solutions for providing the phantom data and their assistance in interpreting and calibrating data from the Biograph PET scanner.  ... 
doi:10.1109/tmi.2011.2149537 pmid:21536530 pmcid:PMC3353661 fatcat:23gouudbkjctnhveu2accsg67q

A unified Fourier theory for time-of-flight PET data

Yusheng Li, Samuel Matej, Scott D Metzler
2015 Physics in Medicine and Biology  
Fully 3D time-of-flight (TOF) PET scanners offer the potential of previously unachievable image quality in clinical PET imaging.  ...  Fourier rebinning equations and other mapping equations among different types of PET data are special cases of the general solutions.  ...  Research reported in this publication was supported in part by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) and the National Cancer Institute (NCI) of the National Institutes  ... 
doi:10.1088/0031-9155/61/2/601 pmid:26689836 pmcid:PMC4826781 fatcat:22qiubxyv5gpnlbz4df6cpvroq

MAP reconstruction for Fourier rebinned TOF-PET data

Bing Bai, Yanguang Lin, Wentao Zhu, Ran Ren, Quanzheng Li, Magnus Dahlbom, Frank DiFilippo, Richard M Leahy
2014 Physics in Medicine and Biology  
Time-of-flight (TOF) information improves signal to noise ratio in Positron Emission Tomography (PET).  ...  Computation cost in processing TOF-PET sinograms is substantially higher than for nonTOF data because the data in each line of response is divided among multiple time of flight bins.  ...  Casey, Vladimir Panin and Christian Michel of Siemens Medical Solutions for their assistance in working with data from Siemens mCT scanner. This work was supported by NIH grant no. R01 EB010197.  ... 
doi:10.1088/0031-9155/59/4/925 pmid:24504374 pmcid:PMC3980855 fatcat:d3tno7joendmnlvnvl2k4wjlru

Exact and approximate rebinning algorithms for 3-D PET data

M. Defrise, P.E. Kinahan, D.W. Townsend, C. Michel, M. Sibomana, D.F. Newport
1997 IEEE Transactions on Medical Imaging  
This second algorithm was implemented and applied to data acquired with the new generation of PET systems and also to simulated data for a scanner with an 18 axial aperture.  ...  This paper presents two new rebinning algorithms for the reconstruction of three-dimensional (3-D) positron emission tomography (PET) data.  ...  Byars for his help and for the use of his 3-D reconstruction software.  ... 
doi:10.1109/42.563660 pmid:9101324 fatcat:hqj56nqdenglvlledzjjrq7hvi

Advances in PET Image Reconstruction

Andrew J. Reader, Habib Zaidi
2007 PET Clinics  
Figs. 1 and 2 illustrate the basic formats of data that can be acquired by a PET scanner, indicating how the measured data are indirect measurements of the unknown activity distribution.  ...  Projections/sinograms are the most popular data format, but as more attributes for each PET event are recorded (ie, not only the coordinates of the two detected photons but also energy and timing measurements  ...  time differences (time of flight), and photon energy.  ... 
doi:10.1016/j.cpet.2007.08.001 pmid:27157872 fatcat:qlqlq7li2nagnp35mqimd52g4e

IMAGE RECONSTRUCTION IN PET

Richard Laforest
2015 Momento  
In this paper we review the basics of PET and discuss the fundamental principle of the physics of PET, the detection of photons and the creation of sinograms.  ...  We also discuss the implementation of the positron range correction and the inclusion of the time-of-flight information for the purpose of improve image contrast and signal to noise.  ...  Acknowledgments I wish to thank all from whom I borrowed material and whom have contributed material on the web.  ... 
doaj:2104805aa88441bfb38391c8d07563d6 fatcat:43aahegcnbcm5oaz6el7mfgbqa

Overview of methods for image reconstruction from projections in emission computed tomography

R.M. Lewitt, S. Matej
2003 Proceedings of the IEEE  
His research interests include methods of tomographic image reconstruction from projections in PET, SPECT, CT, and MRI, with emphasis on data processing and reconstruction approaches for fully three-dimensional  ...  for data collection, and in the computer methods for generating images from the measured data.  ...  ACKNOWLEDGMENT The authors thank the Guest Editors for their encouragement and advice, and thank the reviewers for their detailed  ... 
doi:10.1109/jproc.2003.817882 fatcat:2ii6qap7gbdjtojpbas6uqdqgy

Towards a continuous crystal APD-based PET detector design

Peter Bruyndonckx, Cedric Lemaître, Dennis Schaart, Marnix Maas, D.J. (jan) van der Laan, Magalie Krieguer, Olivier Devroede, Stefaan Tavernier
2007 Nuclear Instruments and Methods in Physics Research Section A : Accelerators, Spectrometers, Detectors and Associated Equipment  
Energy and detector time resolution were 11.5% FWHM and 1.6 ns FWHM, respectively.  ...  Monolithic scintillator blocks provide an efficient way to significantly increase the sensitivity of high-resolution positron emission tomography (PET) systems.  ...  Time-of-Flight (TOF) is also capable of reducing the image variance but is presently limited to whole-body PET.  ... 
doi:10.1016/j.nima.2006.10.058 fatcat:2shimyplzneo3np5fxcx4u6usy

Attenuation correction in emission tomography using the emission data-A review

Yannick Berker, Yusheng Li
2016 Medical Physics (Lancaster)  
In summary, developments using time-of-flight (TOF) PET emission data for AC have shown promising advances and open a wide range of applications.  ...  These techniques may both remedy deficiencies of purely MRI-based AC approaches in PET/MRI and improve standalone PET imaging. C  ...  to 2-D, restoration of missing sinogram data, 102,103 rebinning of TOF data to non-TOF data, 99 and attenuation correction. 60 In fact, consistent TOF PET data satisfy the following two independent  ... 
doi:10.1118/1.4938264 pmid:26843243 pmcid:PMC4715007 fatcat:7oqbi5ttpvblbmmlzi7t5dgjqm

History and future technical innovation in positron emission tomography

Terry Jones, David Townsend
2017 Journal of Medical Imaging  
Whole-body scans for clinical purposes can now be acquired in under 10 min on a state-of-the-art PET/CT.  ...  Spatial resolution has improved by a factor of 10 and sensitivity by a factor of 40 from the early designs in the 1970s to the high-performance scanners of today.  ...  Thus, when acquiring kinetic data from a total-body PET scanner, there are 40,000 possible discrete time-activity curves.  ... 
doi:10.1117/1.jmi.4.1.011013 pmid:28401173 pmcid:PMC5374360 fatcat:dju753desrgtld5rrpufmiwfne

Reproducibility of FDG PET/CT image-based cancer staging and standardized uptake values with simulated reduction of injected FDG dose or acquisition time

Ryan D Niederkohr, Stephen P Hayden, James J Hamill, Judson P Jones, Joshua D Schaefferkoetter, Edison Chiu
2021 American Journal of Nuclear Medicine and Molecular Imaging  
This study aimed to evaluate, using data simulation, if reduction of injected FDG dose or PET acquisition time could be technically feasible when utilizing a sensitive commercial PET/CT imaging system,  ...  mCi/kg at continuous bed motion rate of 1.1 mm/sec.  ...  Acknowledgements The authors would like to thank Mark Westley and Victoria Peckham (Kaiser Permanente Division of Research), and Bijan Farboud and Vijay Shah, PhD (Siemens Medical Systems USA, Inc.) for  ... 
pmid:34754613 pmcid:PMC8569332 fatcat:w2vvwhvgt5gh3db3rzuvsragke

Implementation of TOF-PET Systems on Advanced Reconfigurable Logic Devices [chapter]

J. Torres, R. Garca, A. Aguilar, J. Soret, J. Martos, A.J. Gonzlez, F. Snchez, J.M. Benlloch, M.J. Rodrguez
2013 Positron Emission Tomography - Recent Developments in Instrumentation, Research and Clinical Oncological Practice  
In the above discussion we have considered the 2D tomography problem and the continuous domain. These expressions can be discretized for practical implementation on real TOF-PET data.  ...  In an analytical TOF-PET approach, the image is reconstructed by using a one dimensional time-of-flight weight along the time-of-flight line [43] .  ... 
doi:10.5772/57123 fatcat:bjh2wg2zjvccrcakuahqirq7a4

Dual-Modality Imaging: Combining Anatomy and Function

D. W. Townsend
2008 Journal of Nuclear Medicine  
The combination of CT and PET was introduced commercially in 2001, followed by CT and SPECT in 2004.  ...  Clinical adoption of PET/CT has been surprisingly rapid, and despite continuing debate, the new technology has advanced the use of clinical molecular imaging, particularly for oncology.  ...  FIGURE 6 . 6 Schematic illustrating PET data acquisition with incorporation of time-of-flight (TOF) reconstruction.  ... 
doi:10.2967/jnumed.108.051276 pmid:18483101 fatcat:vry2es3wencffobrka4b2fuxn4

Magnetic Resonance-Guided Positron Emission Tomography Image Reconstruction

Bing Bai, Quanzheng Li, Richard M. Leahy
2013 Seminars in nuclear medicine  
The resolution of PET images is limited by the physics of positron-electron annihilation and instrumentation for photon coincidence detection.  ...  It is therefore now possible to routinely make use of anatomical information in PET reconstruction, provided appropriate methods are available.  ...  Acknowledgments This work was supported by grants R01 EB010197, R21 CA149587 and R01 EB013293.  ... 
doi:10.1053/j.semnuclmed.2012.08.006 pmid:23178087 pmcid:PMC3670801 fatcat:kxuwjq6oz5e3vej6wrrywh4bfy
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