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Congenital aortic disease: 4D magnetic resonance segmentation and quantitative analysis

Fei Zhao, Honghai Zhang, Andreas Wahle, Matthew T. Thomas, Alan H. Stolpen, Thomas D. Scholz, Milan Sonka
2009 Medical Image Analysis  
Automated and accurate segmentation of the aorta in 4D (3D+time) cardiovascular magnetic resonance (MR) image data is important for early detection of congenital aortic disease leading to aortic aneurysms  ...  The automated 4D segmentation resulted in accurate aortic surfaces in all 16 cardiac phases, covering the aorta from the aortic annulus to the diaphragm, yielding subvoxel accuracy with signed surface  ...  Walker and Steven C. Mitchell, as well as Natalie R. Van Waning for their contribution to the project. This work was supported, in part, by the NIH grants R01HL071809 and R0lEB004640.  ... 
doi:10.1016/ pmid:19303351 pmcid:PMC2727644 fatcat:hblw3jldinhyfewbokjoztf6om

Aortic arch shape is not associated with hypertensive response to exercise in patients with repaired congenital heart diseases

Hopewell N Ntsinjana, Giovanni Biglino, Claudio Capelli, Oliver Tann, Alessandro Giardini, Graham Derrick, Silvia Schievano, Andrew M Taylor
2013 Journal of Cardiovascular Magnetic Resonance  
(3D), whole heart magnetic resonance angiography (MRA) at 1.5 Tesla, 3D geometric reconstructions created from the MRA.  ...  This study aims to quantitatively assess whether aortic arch geometry plays a role in blood pressure (BP) response to exercise.  ...  The views expressed in this publication are those of the author(s) and not necessarily those of the NHS, the National Institute for Health Research or the Department of Health.  ... 
doi:10.1186/1532-429x-15-101 pmid:24219806 pmcid:PMC3833644 fatcat:w3iptnjnoba6zhuzomhjbjpega

Is aortopathy in bicuspid aortic valve disease a congenital defect or a result of abnormal hemodynamics? A critical reappraisal of a one-sided argument

Evaldas Girdauskas, Michael A. Borger, Maria-Anna Secknus, Gracijus Girdauskas, Thomas Kuntze
2011 European Journal of Cardio-Thoracic Surgery  
and can only be characterized with sophisticated 4D flow magnetic resonance imaging [11, 12] .  ...  ., metalloproteinase 2 plasma levels) and magnetic resonance imaging tests (i.e., quantitative measurement of the angle of misdirected blood flow) has been recently envisioned as a future diagnostic tool  ... 
doi:10.1016/j.ejcts.2011.01.001 pmid:21342769 fatcat:lbagem6qhvbgtpylnuz53xwism

Computational Simulations Demonstrate Altered Wall Shear Stress in Aortic Coarctation Patients Treated by Resection with End-to-end Anastomosis

John F. Jr. LaDisa, Ronak J. Dholakia, C. Alberto Figueroa, Irene E. Vignon-Clementel, Frandics P. Chan, Margaret M. Samyn, Joseph R. Cava, Charles A. Taylor, Jeffrey A. Feinstein
2011 Congenital Heart Disease  
CFD analysis incorporated downstream vascular resistance and compliance to generate blood flow velocity, time-averaged WSS (TAWSS) and oscillatory shear index (OSI) results.  ...  Differences in WSS indices between groups were negligible more than 5 dAo diameters distal to the aortic arch.  ...  Sources of funding: This work was supported by a Dean's Postdoctoral Fellowship (to JFL), the Vera Moulton Wall Center for Pulmonary Vascular Disease at the Stanford University School of Medicine, and  ... 
doi:10.1111/j.1747-0803.2011.00553.x pmid:21801315 pmcid:PMC3208403 fatcat:b5rhlb3fpzao3kspaxfcox2huu

4D flow cardiovascular magnetic resonance for monitoring of aortic valve repair in bicuspid aortic valve disease

Alexander Lenz, Johannes Petersen, Christoph Riedel, Julius M. Weinrich, Hendrik Kooijman, Bjoern P. Schoennagel, Gerhard Adam, Yskert von Kodolitsch, Hermann Reichenspurner, Evaldas Girdauskas, Peter Bannas
2020 Journal of Cardiovascular Magnetic Resonance  
Our aim was to demonstrate the feasibility of 4D flow cardiovascular magnetic resonance (CMR) to assess the impact of aortic valve repair on changes in blood flow dynamics in patients with symptomatic  ...  Twenty patients with adult congenital heart disease (median 35 years, range 18-64; 16 male) and symptomatic aortic valve regurgitation (15 BAV, 5 UAV) were prospectively studied.  ...  aorta before and after aortic valve repair in patients with congenital heart disease. a Graphs of quantitative analyses of circumferential peak systolic WSS show a significant reduction at the level of  ... 
doi:10.1186/s12968-020-00608-0 pmid:32354361 fatcat:eitm2uwt2rfg5dlsx6l3oeqmtq

MRI hemodynamic markers of progressive bicuspid aortic valve-related aortic disease

Michael D. Hope, Monica Sigovan, S. Jarrett Wrenn, David Saloner, Petter Dyverfeldt
2013 Journal of Magnetic Resonance Imaging  
TAV) controls without valvular disease (n = 12) and patients with BAV (n = 13).  ...  Materials and Methods-25 patients previously studied with 4D Flow imaging who had at least 2 separate cross-sectional imaging studies to assess for aortic growth were included: tricuspid aortic valve (  ...  Example case demonstrating how cross-sectional planes of data were exported and then segmented for quantitative analysis.  ... 
doi:10.1002/jmri.24362 pmid:24788592 pmcid:PMC4010553 fatcat:bq4owxxkfzgeleogni7ibq7bky

Congenital heart disease assessment with 4D flow MRI

Shreyas S. Vasanawala, Kate Hanneman, Marcus T. Alley, Albert Hsiao
2015 Journal of Magnetic Resonance Imaging  
Role of MRI in Congenital Heart Disease Magnetic resonance imaging has a multifaceted role in the management of patients with congenital heart disease.  ...  Visualization and Segmental Analysis Visualization of the intracardiac and extracardiac structures and blood flow is an essential component of the cardiac MRI examination for congenital heart disease.  ... 
doi:10.1002/jmri.24856 pmid:25708923 fatcat:af2yzuojvrcvpp2gqrjyawv77e

4D Flow MRI Applications for Aortic Disease

Nicholas S. Burris, Michael D. Hope
2015 Magnetic Resonance Imaging Clinics of North America  
This article discusses magnetic resonance flow imaging and highlights new flow-related markers in the context of aortic valve disease, valve-related aortic disease, and aortic wall disease.  ...  Aortic disease is routinely monitored with anatomic imaging, but until the recent advent of 3-directional phase contrast MRI (4D) flow, blood flow abnormalities have gone undetected. 4D flow measures aortic  ...  and congenital aortic valve disease  ... 
doi:10.1016/j.mric.2014.08.006 pmid:25476670 pmcid:PMC5127263 fatcat:5rfp4sbbtrcoxcidxte4hg4v2y

Update on non-invasive imaging for congenital heart disease: an additional dimension

Weig, JD, Chelliah A, Lai WW
2014 Reports in Medical Imaging  
Keywords: cardiac magnetic resonance, congenital heart disease, echocardiography, four-dimensional flow, three-dimensional echocardiography  ...  This update focuses on two techniques in which the advances in computer and engineering technologies have allowed for an additional dimension of imaging for patients with congenital heart disease (CHD)  ...  Aortic hemodynamics in patients with and without repair of aortic coarctation: in vivo analysis by 4D flow-sensitive magnetic resonance imaging. Geiger J, Markl M, Herzer L, et al.  ... 
doaj:bee813a9a05a43a0b11e9b432db831d7 fatcat:rcwvnq5du5d5jarapvfjmvpy7m

Congenital Heart Disease

Ali J. Marian
2017 Circulation Research  
We focus on the role of 3 widely used noninvasive imaging techniques in CHD-echocardiography, cardiac magnetic resonance imaging, and cardiac computed tomography.  ...  Congenital heart disease (CHD) is the most common birth defect with an incidence of 1%. 1 Surgical innovations and other advances have led to a growing population of CHD survivors.  ...  Acknowledgments We acknowledge Dr Yoav Dori, MD, PhD, Children's Hospital of Philadelphia and Mr Chris Marcella, RDCS and Mr Matthew Jansen, RDCS, Doernbecher Childrens Hospital for contributing images  ... 
doi:10.1161/circresaha.117.310830 pmid:28302735 pmcid:PMC5378310 fatcat:axesb3c6tnbqlngpeov22tf3we

Unravelling cardiovascular disease using four dimensional flow cardiovascular magnetic resonance

Vivian P. Kamphuis, Jos J. M. Westenberg, Roel L. F. van der Palen, Nico A. Blom, Albert de Roos, Rob van der Geest, Mohammed S. M. Elbaz, Arno A. W. Roest
2016 The International Journal of Cardiovascular Imaging  
Fourdimensional (4D) low cardiovascular magnetic resonance (CMR) has emerged as a suitable technique for comprehensive visualization and quantiication of blood low and energy distribution in the heart  ...  Four-dimensional (4D) low cardiovascular magnetic resonance (CMR) has emerged as a suitable technique that enables visualization of in vivo blood low patterns and quantiication of parameters that could  ... 
doi:10.1007/s10554-016-1031-9 pmid:27888419 pmcid:PMC5489572 fatcat:cj4ceuw6pngkbafu4g4bpbokre

The role of 4D flow MRI for clinical applications in cardiovascular disease: current status and future perspectives

Baiyan Zhuang, Arlene Sirajuddin, Shihua Zhao, Minjie Lu
2021 Quantitative Imaging in Medicine and Surgery  
flow component analysis. 4D flow MRI is widely used to image many parts of the body, such as the neck, brain, and liver, and has a wide application spectrum to cardiac diseases and large vessels.  ...  Magnetic resonance imaging (MRI) four-dimensional (4D) flow is a type of phase-contrast (PC) MRI that uses blood flow encoded in 3 directions, which is resolved relative to 3 spatial and temporal dimensions  ...  Conclusions As a rising blood flow and velocity quantitative analysis technique, 4D flow MRI can provide 3D blood flow coverage and a retrospective blood flow analysis at any location. 4D flow MRI is important  ... 
doi:10.21037/qims-20-1234 pmid:34476199 pmcid:PMC8339660 fatcat:nrj6zyke7rai5nd5f3nr5ousde

Ferumoxytol-enhanced 4D multiphase, steady-state imaging with magnetic resonance in congenital heart disease: ventricular volume and function across 2D and 3D software platforms

Takegawa Yoshida, Joseph J. Chen, Bill Zhou, J. Paul Finn, Peng Hu, Kim-Lien Nguyen
2021 Quantitative Imaging in Medicine and Surgery  
Quantitative ventricular volumetry and function are important in the management of congenital heart disease (CHD).  ...  Ferumoxytol-enhanced (FE) 4D multiphase, steady state imaging with contrast (MUSIC) enables high-resolution, 3D cardiac phase-resolved magnetic resonance imaging (MRI) of the beating heart and extracardiac  ...  R01HL127153 and No. R01HL148182).  ... 
doi:10.21037/qims-21-1243 fatcat:awqd37fdxze6xgstptau2xmx3q

Update on non-invasive imaging for congenital heart disease: an additional dimension

Wyman Lai, Anjali Chelliah, Justin Weigand
2014 Reports in Medical Imaging  
This update focuses on two techniques in which the advances in computer and engineering technologies have allowed for an additional dimension of imaging for patients with congenital heart disease (CHD)  ...  Recent advances in time-resolved 3D velocity mapping, widely known as four-dimensional flow cardiac magnetic resonance, have significantly improved our ability to assess the hemodynamic abnormalities associated  ...  Flowsensitive 4D flow CMR is an ideal method to evaluate these flow patterns in repaired and unrepaired aortic disease.  ... 
doi:10.2147/rmi.s45314 fatcat:5jgsp3qlb5dtvdeysf7hgibuwy

Non-Invasive Imaging for Congenital Heart Disease – Recent Progress in Cardiac MRI

Michael Steinmetz, Hendrik C Preus
2012 Journal of Clinical & Experimental Cardiology  
Cardiac magnetic resonance imaging (CMR) has become an important tool in evaluating congenital heart disease (CHD) in children and adults.  ...  New technologies involve 4D-Flow measurement, "real-time" MRI or as a more future perspective MRI based catheter interventions.  ...  SSFP sequences therefore are generally preferred for the visual and quantitative analysis of wall motion and cardiac function in general.  ... 
doi:10.4172/2155-9880.s8-008 fatcat:ktbtxtuqxjdi5bccsricz6soue
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