88 Hits in 5.6 sec

Labelling Vertebrae with 2D Reformations of Multidetector CT Images: An Adversarial Approach for Incorporating Prior Knowledge of Spine Anatomy [article]

Anjany Sekuboyina, Markus Rempfler, Alexander Valentinitsch, Bjoern H. Menze, Jan S. Kirschke
2021 arXiv   pre-print
We investigated the superiority of the proposed approach for labelling vertebrae on three datasets: a public benchmarking dataset of 302 CT scans and two in-house datasets with a total of 238 CT scans.  ...  Spinal pathologies can have catastrophic consequences, for example, osteoporotic fractures are associated with an 8-fold higher mortality rate in the longterm [1] .  ...  There also exists a wide variation in the field-of-views (FOV) of these scans, which requires an algorithm for detecting landmarks to be robust to key-point identification.  ... 
arXiv:1902.02205v4 fatcat:qbiqgrmjfjgl3f7r25bg2lg4gu

Axial Spondyloarthritis: Mimics and Pitfalls of Imaging Assessment

António Proença Caetano, Vasco V Mascarenhas, Pedro M Machado
2021 Frontiers in Medicine  
The ability to distinguish between imaging lesions suggestive of axSpA and artifacts or lesions suggestive of other disorders is critical for the accurate diagnosis of axSpA.  ...  Diagnosis may be challenging, particularly in early-stage disease and magnetic resonance imaging (MRI) plays a key role in the detection of subtle or inflammatory changes.  ...  Likewise, vertebral osteoporotic fractures constitute a significant cause of low back pain and disability.  ... 
doi:10.3389/fmed.2021.658538 pmid:33968964 pmcid:PMC8100693 fatcat:yjae6zahjvdl5avtoc2cqqoe6i

Bone biosensors: knowing the present and predicting the future

Patricia Khashayar, Ghassem Amoabediny, Bagher Larijani, Jan Vanfleteren
2016 Journal of Micromechanics and Microengineering  
Radiographic vertebral fractures VF were detected in 1/4 of asymptomatic women with low BMD.  ...  Conclusion: Use of glucocorticoids is the major predictor for occurrence of vertebral osteoporotic fractures.  ...  Vertebral compressıon fractures at lumbar vertebrae 4 and 5 were detected by conventional radiography and MRI.  ... 
doi:10.1088/0960-1317/26/2/023002 fatcat:tuwbfvid5jdcfgku3aecotof2i

Abstracts of the ECTS Congress 2018

2018 Calcified Tissue International  
TBS has better predictive value to BMD for the discrimination of vertebral fractures and could help to detect axSpA patients with vertebral fractures.  ...  for adjacent vertebral fracture (AVF) and remote vertebral fracture (RVF) separately.  ...  established risk factor of osteoporotic fractures, there is a huge gap in our knowledge about bone effects of binge drinking in adolescents.  ... 
doi:10.1007/s00223-018-0418-0 pmid:29728722 fatcat:zrpx4rp2srcc7aezjeyg376tqa

Implant-derived magnesium induces local neuronal production of CGRP to improve bone-fracture healing in rats

Yifeng Zhang, Jiankun Xu, Ye Chun Ruan, Mei Kuen Yu, Micheal O'Laughlin, Helen Wise, Di Chen, Li Tian, Dufang Shi, Jiali Wang, Sihui Chen, Jian Q Feng (+16 others)
2016 Nature Medicine  
Hesse for collecting and analyzing the µXRF data. We thank G. Wu and J. Lu for help with scanning electron microscopy analysis.  ...  Recorded runs with a steady walking speed (variation, < 30%) were accepted as compliant runs for paw-print auto-classification as left forelimb (LF), right forelimb (RF), left hind limb (LH) and right  ...  An innovative Mg-IMN system has been developed and has shown therapeutic potential for bone injuries, in particular, for the commonly seen low-energy osteoporotic fracture.  ... 
doi:10.1038/nm.4162 pmid:27571347 pmcid:PMC5293535 fatcat:wnu3jl56pjhbbhp2nqyu4pfn7q

Radiography of the Hip: Lines, Signs, and Patterns of Disease

Scot E. Campbell
2005 Seminars in roentgenology  
Acknowledgement The author expresses appreciation to the Department of Radiology and Imaging at the Hospital for Special Surgery, for the use of images from their teaching file in preparing the manuscript  ...  CT or MR imaging can be helpful in this differential diagnosis by demonstrating the fracture line. 25 Radionuclide bone scan and MR imaging are more sensitive than radiography for early detection of  ...  may be defined as either "fatigue" fractures, occurring from abnormal stress on normally mineralized bone, or "insufficiency" fractures, occurring from normal stress on osteoporotic or poorly mineralized  ... 
doi:10.1053/ pmid:16060117 fatcat:5dx5s3ycsngzrkeaupi6gmezgi

Vitamin D and spinal cord injury: should we care?

J Lamarche, G Mailhot
2016 Spinal Cord  
The close interactions between vitamin D and related bone minerals should be kept in mind when supplementing SCI individuals, and practices should be individualized with clinical conditions.  ...  In the absence of guidelines for the management of vitamin D insufficiency in this high-risk population and in an attempt to provide clinical guidance, considerations for vitamin D supplementation such  ...  found a significant risk reduction for non-vertebral (RR = 0.86, 95% CI, 0.77-0.96) but not for hip (RR = 0.91, 95% CI, 0.78-1.05) fractures.  ... 
doi:10.1038/sc.2016.131 pmid:27645263 fatcat:o5neylxcwrdpxcg5ifs6i3goay

Abstract Book - 93rd National Congress of the Italian Society of Orthopaedics and Traumatology

2008 Journal of Orthopaedics and Traumatology  
Objective Bioscaffolds have been proposed as alternatives to auto-, allo-, xeno-and synthetic grafts in tendon and ligament repair and substitution.  ...  A new type-I collagen membrane developed for use as a tendon graft was tested in vitro and in vivo.  ...  Preliminary outcome of the first 226 consecutive kyphoplasties for the fixation of painful osteoporotic vertebral compression fractures. ISSLS 28th Annual Meeting. Abstract Book, p 109 8.  ... 
doi:10.1007/s10195-008-0030-6 pmid:19384627 pmcid:PMC2657346 fatcat:ttw3od7s4rhyfncny4ielexzv4

Scientific paper sessions

2009 Neuroradiology  
CONCLUSION The expanded histological spectrum, with the currently recognized 4 MB variants, showed overlapping MRI features for classic MB and MB variants.  ...  MATERIALS AND METHODS MR examinations and clinical and pathology reports from 4 institutions, for a total of 28 patients with histologically proven diagnosis of MB, were retrospectively analyzed.  ...  treated with PVP for osteoporotic compression fractures during a 5,5 years period.  ... 
doi:10.1007/s00234-009-0561-4 fatcat:o5kffdrey5e7pp6rpqpvepbowy

Kuskokwim Syndrome, a Recessive Congenital Contracture Disorder, Extends the Phenotype ofFKBP10 Mutations

Aileen M. Barnes, Geraldine Duncan, MaryAnn Weis, William Paton, Wayne A. Cabral, Edward L. Mertz, Elena Makareeva, Michael J. Gambello, Felicitas L. Lacbawan, Sergey Leikin, Andrzej Fertala, David R. Eyre (+2 others)
2013 Human Mutation  
Recessive mutations in FKBP10 at 17q21.2, encoding FKBP65, cause both osteogenesis imperfecta (OI) and Bruck syndrome (OI plus congenital contractures).  ...  Collagen synthesized by KS fibroblasts has substantially decreased hydroxylation of the telopeptide lysine crucial for collagen cross-linking, with 2-10% hydroxylation in probands vs 60% in controls.  ...  Mild skeletal features are common, with osteopenic or osteoporotic vertebrae (L1-L4 zscore from −0.48 to −2.29) and mild vertebral wedging.  ... 
doi:10.1002/humu.22362 pmid:23712425 pmcid:PMC3770534 fatcat:65aksi55pjetfahit24uukgvze

Abstracts of the NIH-FDA Conference "Biomarkers and Surrogate Endpoints: Advancing Clinical Research and Applications"

1998 Disease Markers  
effective therapies for many diseases and disorders.  ...  Adaptation of these biomarkers as substitutes for clinical endpoints, or surrogate endpoints, in clinical trials has taken on new importance in light of the opportunities now before us.  ...  or vertebral fractures.  ... 
doi:10.1155/1998/698239 fatcat:kfeuw7vayffm5da47qgzdv2fyi

Cytokines in Inflammatory Disease

Shinwan Kany, Jan Tilmann Vollrath, Borna Relja
2019 International Journal of Molecular Sciences  
They can be used as biomarkers to indicate or monitor disease or its progress, and also may serve as clinically applicable parameters for therapies.  ...  bone loss and wrist fracture among older women [241] meta-analysis bone IL6-174 G/C gene polymorphism positively correlated with osteoporosis risk [242, 243] in vivo bone Variation within the low  ...  It is composed of players and mediators that are common to most vertebrates and invertebrates, as well as even plants [1] .  ... 
doi:10.3390/ijms20236008 pmid:31795299 pmcid:PMC6929211 fatcat:wvoefhwfbjglffdjh3x2biamlu

Effects of Adapted Physical Activity on Quality of Life, Physical Fitness and Fear of Falling in People with Osteoporosis

Sofia Marini
Vertebral Fractures Vertebral fracture is the most common and usually the first osteoporotic fracture to occur, being present in 15% of women aged 50 to 59 years, 15% of men aged 69 to 81 years, and 50%  ...  Vertebral fracture risk is 20% in the year following incident vertebral fracture.  ...  Appendix Instructions for participant  ... 
doi:10.48676/unibo/amsdottorato/9701 fatcat:pce5dsb3vvdanev7nrkv4vz6xy

Abstracts from the 53rd European Society of Human Genetics (ESHG) Conference: e-Posters

2020 European Journal of Human Genetics  
Resistance to fatigue and muscle stiffness are considered risk factors for ACL injury.  ...  R packages were used for statistical analysis. The genotype distributions of all control groups were in HWE.  ...  (Gly11Arg)) was detected. GLA -encodes a homodimeric glycoprotein.  ... 
doi:10.1038/s41431-020-00741-5 pmid:33262486 fatcat:m6by7js7kfbi5ayebbpywf6ppu

Supplmentum 245: Annual Congress of the Swiss Society of Rheumatology

2020 Swiss Medical Weekly  
The highest rate of opioids prescription at discharge was observed in patients hospitalized for osteoporotic fracture (38%) and severe low back pain (35%).  ...  These were compared between osteoporotic and non-osteoporotic patients, osteoporosis being defined as a BMD value < = -2.5 DS or the presence of an atraumatic fracture regardless of the BMD.  ...  In total, 10.50% of the participants had a prevalent, low-impact fracture; and, after 5-years of follow up, 5.91% had an incident, low-impact fracture.  ... 
doi:10.4414/smw.2020.20359 pmid:32869212 fatcat:bxknytqdg5b5znurpqxv3gypbe
« Previous Showing results 1 — 15 out of 88 results