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An Approach for Leukemia Classification Based on Cooperative Game Theory

Atefeh Torkaman, Nasrollah Moghaddam Charkari, Mahnaz Aghaeipour
2011 Analytical Cellular Pathology  
The result demonstrates that cooperative game is very promising to be used directly for classification of leukemia as a part of Active Medical decision support system for interpretation of flow cytometry  ...  Hematological malignancies are the types of cancer that affect blood, bone marrow and lymph nodes.  ...  An expert system for detecting breast cancer based on association rules (AR) and neural network was developed in [15] .  ... 
doi:10.1155/2011/212174 pmid:21988887 pmcid:PMC4605502 fatcat:rrt4ig3zzrhm3nrefet6nkp6ca

Automated Analysis of Fluorescent in situ Hybridization (FISH) Labeled Genetic Biomarkers in Assisting Cervical Cancer Diagnosis

Xingwei Wang, Bin Zheng, Roy R. Zhang, Shibo Li, Xiaodong Chen, John J. Mulvihill, Xianglan Lu, Hui Pang, Hong Liu
2010 Technology in Cancer Research and Treatment  
This preliminary study demonstrates that the feasibility of potentially applying the automatic FISH analysis method to expedite the screening and detecting cervical cancer at an early stage.  ...  The numerical and/or structural deviation of some chromosomes (i.e., monosomy and polysomy of chromosomes 3 and X) are routinely used as positive genetic biomarkers to diagnose cervical cancer and predict  ...  Acknowledgments This research is supported in part by grants from the National Institute of Health (CA136700).  ... 
doi:10.1177/153303461000900302 pmid:20441233 pmcid:PMC2916642 fatcat:uunzywcozzbexb3pqh7d2m7exa

Intelligent Techniques Using Molecular Data Analysis in Leukaemia: An Opportunity for Personalized Medicine Support System

Haneen Banjar, David Adelson, Fred Brown, Naeem Chaudhri
2017 BioMed Research International  
Most studies used molecular data analysis for personalized medicine, but future advancement for leukaemia patients requires molecular models that use advanced machine-learning methods to automate decision-making  ...  Until now, no reviews have been published from a computational perspective concerning the development of personalized medicine intelligent techniques for leukaemia patients using molecular data analysis  ...  Acknowledgments Financial support for this study was provided in part by a grant from King Abdulaziz University.  ... 
doi:10.1155/2017/3587309 pmid:28812013 pmcid:PMC5547708 fatcat:ylwvfw74bfhetayzundiylofg4

Undifferentiated Sarcomas: What to Do? And Does It Matter? A Surgical Pathology Perspective

Christopher D. M. Fletcher
2008 Ultrastructural Pathology  
During this talk, a brief description of the microarray methodology and data analysis will be provided, followed by few examples of the recent applications of gene expression in the diagnosis, classification  ...  . • Pathologic subclassification of all sarcomas, where possible, is the main avenue by which advances in diagnosis, prognostication and therapeutic stratification are made. • Attempts to subclassify round  ...  of any more specific diagnosis on local treatment decisions.  ... 
doi:10.1080/01913120801896945 pmid:18446665 fatcat:7zr3wugsr5b4zf2q5lv5axq4ze

Abstracts for the 34th HGSA Annual Scientific Meeting, Melbourne, Australia November 16-18, 2010

2010 Twin Research and Human Genetics  
Introduction: The congenital disorders of protein glycosylation are a family of enzyme defects in assembly (Type I), transfer, and remodeling (Type II) of glycan structures to proteins.  ...  Although the pathogenesis of CLN3 remains incomplete, it is now clear that at least part of the neuronal cell death is triggered by increased intracellular calcium content and the apoptosis pathway.  ...  Our team developed a decision aid called Making Choices for women considering prenatal diagnosis.  ... 
doi:10.1375/twin.13.6.620 fatcat:waz3wo2snrgdjigvmen5y2qtaq

7thESACP Congress in Caen April 1–5, 2001

2001 Analytical Cellular Pathology  
parts, whereas in a uterine leiomyomatous process the necrotic parts only may lead to a diagnosis of sarcoma.  ...  breast cancer.  ...  Pairs of images of any diagnosis, magnification and staining  ... 
doi:10.1155/2001/414753 fatcat:7vxekd2dbjherbnpv5q7dshpsu

Epigenetics in Cancer: The Myelodysplastic Syndrome as a Model to Study Epigenetic Alterations as Diagnostic and Prognostic Biomarkers [chapter]

Teresa de Souza Fernandez, Andr Mencalha, Ceclia de Souza Fernandez
2012 Biomarker  
In these cases, important diagnostic tools, like the cytogenetics and the immunophenotyping, aid this diagnosis (Bennett & Orazi, 2009; Wong & So, 2002) .  ...  The cytogenetics evaluation of a bone marrow sample from patients with MDS has become an integral part of clinical care.  ... 
doi:10.5772/38754 fatcat:3unaxhxi35gwjjiuw5pwhmsodm

Optimising the management of soft tissue tumours

Chris Hemmings, Carina Miles, John Slavin, S. Fiona Bonar, Nicole Graf, Lyn Austen, David Thomas, Jayesh Desai, Peter Barry
2011 Pathology (Sydney)  
of structures such as major nerves or blood vessels, can aid diagnosis.  ...  part of the report summary or 'diagnosis' field in the final pathology report.  ... 
doi:10.1097/pat.0b013e3283464427 pmid:21516052 fatcat:wfqezw7mwne4pfel72rdqdavue

NCCN Task Force Report: Evaluating the Clinical Utility of Tumor Markers in Oncology

Phillip G. Febbo, Marc Ladanyi, Kenneth D. Aldape, Angelo M. De Marzo, M. Elizabeth Hammond, Daniel F. Hayes, A. John Iafrate, R. Kate Kelley, Guido Marcucci, Shuji Ogino, William Pao, Dennis C. Sgroi (+1 others)
2011 The Journal of the National Comprehensive Cancer Network  
Hedvat, MD, PhD, and a molecular testing expert from the Centers for Medicare & Medicaid Services (CMS) for critical reading of sections of this manuscript.  ...  Diagnostic Markers A large category of molecular tests aid in the diagnosis or subclassification of a particular disease state.  ...  alone, testing for the presence of the fusion protein might be useful to aid in the diagnosis of pilocytic astrocytoma when histologic features are inconclusive and difficult to distinguish from a diffuse  ... 
doi:10.6004/jnccn.2011.0137 pmid:22138009 fatcat:hvo3qypxczhddmgxaozlttmsza

Physician, Patient, and Contextual Factors Affecting Treatment Decisions in Older Adults With Cancer and Models of Decision Making: A Literature Review

Joseph D. Tariman, Donna L. Berry, Barbara Cochrane, Ardith Doorenbos, Karen G. Schepp
2011 Oncology Nursing Forum  
cancer who were found to use expert opinion heuristics because of decisional uncertainty and systematic information processing to cope with the diagnosis.  ...  Highly applicable in decision-making conditions in which time is ample to deliberate on choices and involve the use of decisional aids The DSF is less useful for decisions with no immediate stimulus for  ... 
doi:10.1188/12.onf.e70-e83 pmid:22201670 pmcid:PMC3247918 fatcat:wps27yfuivcjpfhzqpe3xoclyi

Personalized Medicine Support System : Resolving Conflict in Allocation to Risk Groups and Predicting Patient Molecular Response to Targeted Therapy

Haneen Banjar, David Adelson, Fred Brown, Tamara Leclercq
2017 Health Informatics - An International Journal  
The reuse of medical data and knowledge for cancer treatment requires advanced computational methods such as intelligent systems.  ...  The path from the root of the tree to the leaf node was used to establish the conditions (IF parts), whereas every leaf of a decision tree corresponded to a response (THEN parts).  ... 
doi:10.5121/hiij.2017.6201 fatcat:ez7zg7puyjfvlp5tujrke6di2e

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2009, n°1 - Full issue

2011 Atlas of Genetics and Cytogenetics in Oncology and Haematology  
However, established breast cancer cell-lines express neither ST6GalNAc I nor STn .  ...  Prognosis Poor, decreased survival of the patients Breast Cancer Note ST6GalNAc I is responsible for the synthesis of the tumor-associated STn O-glycan in human breast cancer (Sewell et al., 2006) .  ...  Cytogenetics Cytogenetics morphological The patient had a ins(12;8)(p11;p12p22) at diagnosis of the NHL; monosomy 7 was found as an additionnal anomaly at the time of the AML onset Genes involved  ... 
doi:10.4267/2042/45324 fatcat:222l4mxzhndozczwoutx2ajcni

Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Onkologie. Berlin, 1.–5. Oktober 2010, pp 67–108

2010 Onkologie (Basel)  
Hepatic lesions can be detected by computerized tomographic (CT) scans, but there is no standardized CT protocol for the diagnosis and follow-up of hepatic candidiasis.  ...  Patient and methods: During a routine check up in 12/07 a tumour on the right kidney was discovered in a 40 y old female. Suspicious for renal cell cancer, a laparoscopic nephrectomy was performed.  ...  Is any of these points relevant for cytogenetics of MDS which might vote for a diagnosis of MDS without cytogenetics?  ... 
doi:10.1159/000321409 fatcat:ta576fjarjgvha4udymfzpf3re

Coverage of new genetic technologies: what matters to insurers?

M Schoonmaker, B Bernhardt, N A Holtzman
1996 American Journal of Human Genetics  
As part of our work directed toward the construction of a mouse model of HD, we have introduced the 5' end of the mutated human HD gene into the mouse germ line.  ...  decisions would be made for cystic fibrosis carrier screening (CFCS), BRCAl testing, and gene therapy for CF (GTCF). 76% have never made a coverage decision for CFCS. 39% of insurers would cover the baseline  ...  Individuals are extremely sensitive to the effects of ionizing radiation. Heterozygous carriers may have a predisposition to cancer, particularly breast cancer.  ... 
pmid:11644831 pmcid:PMC1915515 fatcat:int6jaa25bbszfs2lblwvhck44

Poster Presentation Abstracts

Scientific Committee
1969 Journal of cancer and allied specialties  
Conclusion: The diagnosis of duodenal obstruction is made with CT scan with oral contrast and may demonstrate dilatation of the proximal duodenum with failure of contrast passage beyond the third part  ...  Most favourable survival was for ampullary cancer with average 637 days and the worst for pancreatic cancer with average survival of 249 days.  ...  Yet, sonography based swift and early diagnosis is often of a great help to the clinicians. Neutropenic colitis is one of the noteworthy examples, where prompt diagnosis is crucial.  ... 
doi:10.37029/jcas.v3i4.160 fatcat:rm425uez6bhavjwzrn25js74bm
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