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Imaging for Viable and Ischemic Myocardium [chapter]

Catalin Loghin, K. Lance Gould
2008 Interventional Treatment of Advanced Ischemic Heart Disease  
(ii) Viability assessment: SPECT or PET imaging are indicated in patients with known CAD after myocardial infarction or by cardiac catheterization with dysfunctional myocardial segments by echocardiography  ...  The size of myocardial infarction determined by the size of the defect in 82 Rb uptake on rest images equals the size of myocardial infarction as detected by FDG imaging [67, 79] .  ... 
doi:10.1007/978-1-84800-395-8_2 fatcat:frorxjirencczbn7ckuhumhzca

Role of thallium-201 and PET imaging in evaluation of myocardial viability and management of patients with coronary artery disease and left ventricular dysfunction

J Maddahi, H Schelbert, R Brunken, M Di Carli
1994 Journal of Nuclear Medicine  
Thallium-201 rest-redistribution myocardial scintigraphy and PET imaging of myocardial perfusion and 18F-fluoro-deoxyglucose metabolism have been extensively evaluated for the assessment of myocardial  ...  viability and for prediction of recovery of regional left ventricular dysfunction following myocardial revascularization; with positive and negative predictive accuracies of 72% and 70% for 201Tl rest-redistribution  ...  PET With PET, positron-emitting radionuclides are utilized to obtain tomographic images of regional myocardial per fusion, metabolism and receptor density.  ... 
pmid:8151399 fatcat:gmoudxoqengpnj5sgsgl5w3niy

Myocardial viability assessment by endocardial electroanatomic mapping: comparison with metabolic imaging and functional recovery after coronary revascularization

Karl-Christian Koch, Juergen vom Dahl, Monika Wenderdel, Bernd Nowak, Wolfgang M Schaefer, Alexander Sasse, Christoph Stellbrink, Udalrich Buell, Peter Hanrath
2001 Journal of the American College of Cardiology  
OBJECTIVES The objective of this study was to compare electroanatomic mapping for the assessment of myocardial viability with nuclear metabolic imaging using positron emission computed tomography (PET)  ...  METHODS Forty-six patients with prior (Ն2 weeks) myocardial infarction underwent fluorine-18 fluorodeoxyglucose (FDG) PET and Tc-99m sestamibi single-photon emission computed tomography (SPECT) before  ...  Comparison of electroanatomic mapping with PET/ SPECT and RWM in infarct area.  ... 
doi:10.1016/s0735-1097(01)01314-6 pmid:11451302 fatcat:ckymio6lvfhdxk3pyopreyk7py

Positron Emission Tomography in Coronary Heart Disease

José de Almeida, Sofia Martinho, Lino Gonçalves, Maria Ferreira
2022 Applied Sciences  
With advances in scanner technology, postprocessing techniques, and the development of novel positron emission tomography (PET) tracers, the applications of PET for the study of coronary heart disease  ...  imaging) and viable versus scarred (viability imaging) myocardium.  ...  Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/app12094704 fatcat:pvsanlp5x5d57arrvx47mnh4fe

Assessment of Myocardial Viability in Patients with Heart Failure

A. F.L. Schinkel, D. Poldermans, A. Elhendy, J. J. Bax
2007 Journal of Nuclear Medicine  
Noninvasive assessment of myocardial viability may guide patient management.  ...  PET, 201 Tl and 99m Tc scintigraphy, and dobutamine stress echocardiography have been extensively evaluated for assessment of viability and prediction of clinical outcome after coronary revascularization  ...  PET with 13 N-ammonia and 18 F-FDG to assess myocardial viability (26).  ... 
doi:10.2967/jnumed.106.038851 pmid:17574986 fatcat:67ipdcrnmbggvla2zlqxzbz72u

Multimodality imaging of myocardial viability: an expert consensus document from the European Association of Cardiovascular Imaging (EACVI)

Ana G Almeida, John-Paul Carpenter, Matteo Cameli, Erwan Donal, Marc R Dweck, Frank A Flachskampf, Alicia M Maceira, Denisa Muraru, Danilo Neglia, Agnès Pasquet, Sven Plein, Bernhard L Gerber (+1 others)
2021 European Heart Journal-Cardiovascular Imaging  
Cardiac imaging may allow identification of myocardial viability through different principles, with the purpose of prediction of therapeutic response and selection for treatment.  ...  In clinical decision making, myocardial viability is defined as myocardium in acute or chronic coronary artery disease and other conditions with contractile dysfunction but maintained metabolic and electrical  ...  In the same or a different session, an 18F-FDG PET scan is acquired 60-90 min after tracer injection to assess metabolic activity. 11 Comparison is then usually made between the rest perfusion and FDG  ... 
doi:10.1093/ehjci/jeab053 pmid:34097006 fatcat:mfmxs7yzt5etlddi4xy3uv4wb4

Diagnostic value of (18)F-FDG PET in the assessment of myocardial viability in coronary artery disease: A comparative study with (99m)Tc SPECT and echocardiography

Mansour Al Moudi, Zhong-Hua Sun
2014 Journal of Geriatric Cardiology  
To investigate the diagnostic value of 18F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) in the assessment of myocardial viability in patients with known coronary artery disease (CAD)  ...  in the assessment of myocardial viability in patients with known CAD when compared to SPECT and echocardiography.  ...  We declare that there is no conflict of interest in this study.  ... 
doi:10.11909/j.issn.1671-5411.2014.03.008 pmid:25278972 pmcid:PMC4178515 fatcat:xdk6mrg5frazrlx4nqq7ydrkoy

Cardiac PET/MRI—an update

C. Rischpler, S. G. Nekolla, G. Heusch, L. Umutlu, T. Rassaf, P. Heusch, K. Herrmann, F. Nensa
2019 European Journal of Hybrid Imaging  
Early after, reports on the first use of PET/MRI in oncological patients were released.  ...  In this review article, we give an overview on technical updates within these last years with potential impact on cardiac imaging and summarize those scenarios where PET/MRI plays a pivotal role in cardiovascular  ...  Availability of data and materials Not applicable.  ... 
doi:10.1186/s41824-018-0050-2 pmid:34191143 fatcat:jmhlxmiekndmlnd4snx2e7kjfa

Clinical Utility and Future Applications of PET/CT and PET/CMR in Cardiology

Jonathan Pan, Michael Salerno
2016 Diagnostics  
Aside from software approaches that fuse images after acquisition, PET/MRI systems are designed so that patients are imaged either sequentially or in parallel (Figure 1 ).  ...  CMR has excellent soft tissue characterization that would complement PET molecular imaging, particularly in understanding infarct viability, ventricular remodeling, inflammatory processes and infiltrative  ...  [118] looked at 28 patients with acute myocardial infarct who underwent simultaneous PET/CMR for 18 F-FDG uptake and LGE imaging after revascularization.  ... 
doi:10.3390/diagnostics6030032 pmid:27598207 pmcid:PMC5039566 fatcat:63crv4k2ubb5bj6vazp2evsro4

Imaging of metabolism and autonomic innervation of the heart by positron emission tomography

Pierre M�lon, Markus Schwaiger
1992 European Journal of Nuclear Medicine  
More recently, PET has emerged in cardiology as a useful tool for the detection of coronary artery disease and the evaluation of tissue viability.  ...  Clinical studies have indicated that the metabolic imaging is helpful in selecting patients for coronary artery bypass surgery or coronary angioplasty.  ...  Reduced resting perfusion (left panel) with matched reduced FDG retention (right panel) in the inferolateral wall of this patient with prior inferior myocardial infarction represents non-viable myocardium  ... 
doi:10.1007/bf00177375 pmid:1618239 fatcat:xrduxmizzfe77kbkhri65q22vy

Chronic Ischemic Left Ventricular Dysfunction

Shahbudin H. Rahimtoola, Vasken Dilsizian, Christopher M. Kramer, Thomas H. Marwick, Jean-Louis J. Vanoverschelde
2008 JACC Cardiovascular Imaging  
Chronic ischemic left ventricular dysfunction is present in a number of clinical syndromes in which myocardial revascularization results in an improvement of left ventricular function, patients' functional  ...  Early diagnosis of and treatment of viability is essential. Coronary arteriography is of limited value in diagnosis of viability.  ...  Thus, metabolic imag-ing with FDG PET may provide incremental information to thallium regarding myocardial viability, especially in patients with severely impaired LVD (63) .  ... 
doi:10.1016/j.jcmg.2008.05.009 pmid:19356479 pmcid:PMC2664223 fatcat:ky7xswl4ercibiwaz7teqd7ham

Nuclear cardiology, Part IV: Viability

L Mesotten, A Maes, A S Hambye, H Everaert, V Van den Maegdenbergh, P Franken, L Mortelmans
1999 Journal of Nuclear Medicine Technology  
imaging protocols used for detecting viability with SPECT; (c) the different radiopharmaceuticals and imaging protocols used for detecting viability with PET; and (d) the imaging patterns observed after  ...  reconstructing myocardial images.  ...  Direct comparisons between FDG SPECT and FDG PET have shown that the assessment of myocardial viability is comparable for both techniques (72, 73) The 3 methods to optimize the glucose uptake rate in  ... 
pmid:10353105 fatcat:xz6s6pmes5gpjmg6um2hyzp7be

Assessment of myocardial ischaemia and viability: role of positron emission tomography

N. Ghosh, O. E. Rimoldi, R. S. B. Beanlands, P. G. Camici
2010 European Heart Journal  
of myocardial metabolism and viability in patients with ischaemic left ventricular dysfunction.  ...  principles behind PET imaging and its main clinical applications in cardiology, namely the assessment of MBF and metabolism. --- Keywords Myocardial ischaemia † PET Myocardial perfusion imaging and quantification  ...  Traditional 18 FDG-PET myocardial viability assessment requires integration of rest perfusion imaging with myocardial glucose metabolism imaging.  ... 
doi:10.1093/eurheartj/ehq361 pmid:20965888 fatcat:mrwf4aree5a3fn7sxjgpx3q27m

Positron emission tomography myocardial perfusion and glucose metabolism imaging

2006 Journal of Nuclear Cardiology  
N-13 ammonia and Rb-82 are well-accepted myocardial perfusion agents [3] [4] [5] [6] [7] [8] [9] for rest and stress PET myocardial imaging or in combination with FDG for determination of viability.  ...  Special considerations for combining SPECT perfusion with PET metabolism images. In current clinical practice, FDG PET images are often read in combination with SPECT myocardial perfusion images.  ... 
doi:10.1016/j.nuclcard.2006.08.009 pmid:17174789 fatcat:7c7x2tcoxraxveeirjt7rqoxnm

New SPECT and PET Radiopharmaceuticals for Imaging Cardiovascular Disease

Oyebola O. Sogbein, Matthieu Pelletier-Galarneau, Thomas H. Schindler, Lihui Wei, R. Glenn Wells, Terrence D. Ruddy
2014 BioMed Research International  
that optimize image quality with reduced radiation exposure are fuelling a resurgence of interest at the preclinical and clinical levels to expand beyond MPI.  ...  The relevant radiochemistry and preclinical and clinical development in addition to molecular imaging with emerging modalities such as cardiac MRI and PET-MR will be discussed.  ...  Current SPECT and PET Tracers Used in Myocardial Metabolism and Viability 3.1. 18 F-Fluorodeoxyglucose for PET Viability Imaging.  ... 
doi:10.1155/2014/942960 pmid:24901002 pmcid:PMC4034657 fatcat:klvtv23jbrasniue6wclszttxi
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