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Patient-specific modeling of dyssynchronous heart failure: A case study

Jazmin Aguado-Sierra, Adarsh Krishnamurthy, Christopher Villongco, Joyce Chuang, Elliot Howard, Matthew J. Gonzales, Jeff Omens, David E. Krummen, Sanjiv Narayan, Roy C.P. Kerckhoffs, Andrew D. McCulloch
2011 Progress in Biophysics and Molecular Biology  
The development and clinical use of patient-specific models of the heart is now a feasible goal. Models have the potential to aid in diagnosis and support decision-making in clinical cardiology.  ...  Here we describe the methodology for generating a patient-specific model of the failing heart with a myocardial infarct and left ventricular bundle branch block.  ...  Acknowledgments Funding Sources The study has been supported by NIH grant R01 HL96544 (to A.D.M.) and the National Biomedical Computation Resource (NIH grant P41 RR08605) (to A.D.M).  ... 
doi:10.1016/j.pbiomolbio.2011.06.014 pmid:21763714 pmcid:PMC3190065 fatcat:ho6674zlbzdg3mbt6jwyy4opfm

Effect of initial plant density on modeling accuracy of the revised sparse Gash model: a case study of Pinus tabuliformis plantations in northern China

Yiran Li, Xiaohua Liu, Zedong Li, Ye Zhao, Yong Niu, Chuanjie Zhang
2020 Hydrology Research  
Previous studies have proven that changes in initial plant density, which are caused by thinning, affect the accuracy of RSGM; however, the direct effect of initial density on modeling accuracy remains  ...  poorly understood because few studies have collected field data of the same species with various initial densities under similar site conditions.  ...  . () suggested that raindrop characteristics and leaf biomechanical properties may influence the modeling of the dynamic processes of forest canopy interception.  ... 
doi:10.2166/nh.2020.007 fatcat:q44otqgcbzbvveztwvcqurk3nu

Combined forced oscillation and fractional-order modeling in patients with work-related asthma: a case–control study analyzing respiratory biomechanics and diagnostic accuracy

Fábio Augusto d´Alegria Tuza, Paula Morisco de Sá, Hermano A. Castro, Agnaldo José Lopes, Pedro Lopes de Melo
2020 BioMedical Engineering OnLine  
These models could be useful for biomechanical studies and diagnostic purposes, offering accurate models with an improved ability to describe nature.  ...  Background Fractional-order (FrOr) models have a high potential to improve pulmonary science.  ...  A comparison between the present results and those of a preliminary study, including all asthma phenotypes [28] , confirms the ability of this parameter to describe the presence of heterogeneous peripheral  ... 
doi:10.1186/s12938-020-00836-6 pmid:33298072 fatcat:okm2kga72namnptwtuhi2sqr3q

Wind Speed Controls Forest Structure in a Subtropical Forest Exposed to Cyclones: A Case Study Using an Individual-Based Model

E-Ping Rau, Barry A. Gardiner, Fabian Jörg Fischer, Isabelle Maréchaux, Emilie Joetzjer, I-Fang Sun, Jérôme Chave
2022 Frontiers in Forests and Global Change  
In this study, we coupled an individual-based and spatially-explicit forest dynamics model (TROLL) with a mechanistic model estimating wind damage as a function of tree size, traits, and allometry (ForestGALES  ...  Individual-based modeling provides a framework in which to investigate the impact of wind regimes on mortality, other factors influencing wind-induced tree mortality, as well as interaction between wind  ...  In this study, we explored the community-wide consequences of wind disturbances, using a model-based approach.  ... 
doi:10.3389/ffgc.2022.753100 fatcat:qte4yvaq3ncjlaoqdhpnfad3pi

Simulating the effect of high-intensity sound on cetaceans: Modeling approach and a case study for Cuvier's beaked whale (Ziphius cavirostris)

P. Krysl, T. W. Cranford, S. M. Wiggins, J. A. Hildebrand
2006 Journal of the Acoustical Society of America  
A finite element model is formulated to study the steady-state vibration response of the anatomy of a whale ͑Cetacea͒ submerged in seawater.  ...  The computational model was applied to the study of the response of the tissues within the head of a neonate Cuvier's beaked whale Ziphius cavirostris.  ...  The specimen of Ziphius cavirostris used in this study and in Soldevilla et al. ͑2005͒, was  ... 
doi:10.1121/1.2257988 pmid:17069328 fatcat:x4w6jih3xjahlhmb3torkbw3n4

Aboveground net primary productivity of a beech (Fagus moesiaca) forest: a case study of Naousa forest, northern Greece

D. Zianis, M. Mencuccini
2005 Tree Physiology  
Although small trees (diameter at breast height < 10 cm) were not sampled, it was unlikely that this accounted for the low L* because there were very few small trees on a per-hectare basis.  ...  Further research is needed to test these hypotheses and to determine the belowground dynamics of phytomass in this ecosystem.  ...  Dimitris Zianis was partially supported by a State Foundation of Greece Scholarship (IKY).  ... 
doi:10.1093/treephys/25.6.713 pmid:15805091 fatcat:mn5ms64tt5e4noaljov36gevc4

Multimodal Patient-Specific Registration for Breast Imaging Using Biomechanical Modeling with Reference to AI Evaluation of Breast Tumor Change

Cheng Xue, Fuk-Hay Tang, Christopher W. K. Lai, Lars J. Grimm, Joseph Y. Lo
2021 Life  
How to build a breast biomechanical model simulating the large-scale deformation of soft tissue remains a challenge but is highly desirable.  ...  Methods: This study proposed a hybrid individual-specific registration model of the breast combining finite element analysis, property optimization, and affine transformation to register breast images.  ...  Conflicts of Interest: The authors declare no conflict of interest. Life 2021, 11, 747  ... 
doi:10.3390/life11080747 pmid:34440490 pmcid:PMC8401473 fatcat:7xaotv7cbzeazj6tzj7xswgxki

A review of deep learning in medical imaging: Image traits, technology trends, case studies with progress highlights, and future promises [article]

S. Kevin Zhou, Hayit Greenspan, Christos Davatzikos, James S. Duncan, Bram van Ginneken, Anant Madabhushi, Jerry L. Prince, Daniel Rueckert, Ronald M. Summers
2020 arXiv   pre-print
We conclude with a discussion and presentation of promising future directions.  ...  It is known that the success of AI is mostly attributed to the availability of big data with annotations for a single task and the advances in high performance computing.  ...  Further, rather than presenting an exhaustive literature survey for each studied case, we provide some prominent progress highlights in each case study. A.  ... 
arXiv:2008.09104v1 fatcat:z2gic7or4vgnnfcf4joimjha7i

Factors influencing the accuracy of biomechanical breast models

Christine Tanner, Julia A. Schnabel, Derek L. G. Hill, David J. Hawkes, Martin O. Leach, D. Rodney Hose
2006 Medical Physics (Lancaster)  
This study evaluated the accuracy with which biomechanical breast models based on finite element methods can predict the displacements of tissue within the breast in the practical clinical situation where  ...  Recently it has been suggested that finite element methods could be used to predict breast deformations in a number of applications, including comparison of multimodality images, validation of image registration  ...  Castellano-Smith for their help in image acquisition or model construction. One of the authors ͑C.T.͒ was supported by EPSRC GR/ M52779 and MIAS-IRC ͑EPSRC GR/N14248/01, UK MRC D2025/31͒.  ... 
doi:10.1118/1.2198315 pmid:16872083 fatcat:5gjvaqqzfzhana7ffceoyhxojq

Does commercialization of a non-timber forest product reduce ecological impact? A case study of the Critically Endangered Aquilaria crassna in Lao PDR

Anders Jensen, Henrik Meilby
2008 Oryx  
In the case of A. crassna in Laos it therefore appears that the activities of highly commercialized harvesters are less harmful to A. crassna populations than those of less specialized, local harvesters  ...  For comparison we included data on number of trees felled during the most recent harvesting trip.  ...  The study was funded by the University of Copenhagen and the Danish Ministry of Foreign Affairs.  ... 
doi:10.1017/s0030605308007825 fatcat:cjzdj34wyjem5hrvt32t7tr6dm

The Association between Bone Mineral Density, Metacarpal Morphometry, and Upper Limb Fractures in Children: A Population-Based Case-Control Study

Deqiong Ma, Graeme Jones
2003 Journal of Clinical Endocrinology and Metabolism  
A total of 321 fracture cases and 321 randomly selected individually matched controls were studied. For all fractures, cases had lower DXA measures at all sites (1.1-3.3%; all P < 0.05).  ...  The aim of this population-based case-control study was to examine the association between bone mass and upper limb fractures in children aged 9 -16 yr.  ...  Acknowledgments We thank research assistants Fiona Wilson, Anitra Wilson, Lesley Oliver, and Val Walsh and biostatisticians Leigh Blizzard and Jim Stankovich as well as the staff of the Medical Imaging  ... 
doi:10.1210/jc.2002-021682 pmid:12679427 fatcat:ujeoaygtojat7llhkoiqpokcri

A novel breast software phantom for biomechanical modeling of elastography

Syeda Naema Bhatti, Mallika Sridhar-Keralapura
2012 Medical Physics (Lancaster)  
The authors report a 3D software breast phantom that was built using a mechanical design tool, to investigate the biomechanics of elastography using finite element modeling (FEM).  ...  Residual modulus, maps, and profiles, served as a guide to optimize meshing of this geometrically nonlinear phantom for biomechanical modeling of elastography.  ...  ., 2 there are three major requirements for developing a realistic biomechanical model of the breast.  ... 
doi:10.1118/1.3690467 pmid:22482599 fatcat:mt56kv5zqbb4xa3chbcufks3da

Qualitative and quantitative analyses of tree forking habit with single-image photogrammetry: a case study of old-growth temperate oaks in a mixed, deciduous forest remnant near Krakow, Poland [article]

Kamil Waldemar Kędra
2019 bioRxiv   pre-print
Two of the models were most clearly represented by the studied oaks.  ...  A new classification of mature oak architectures was proposed, based on the original Hallé-Oldeman model, with modified locations of the main branches and presence or absence of bifurcation in the main  ...  Two of the models were most clearly represented by the studied oaks.  ... 
doi:10.1101/795286 fatcat:4ptbqsml6zbpvmzap7upkw6ctq

Breast Tumors Diagnosis Using Finite Element Modelling

Mohamed A Naser, Ahmed M Sayed, Ashraf A Wahba, Mohamed AA Eldosoky
2018 Journal of Biomedical Sciencies  
These forces had been applied breast's model after constructing for different positions and sizes of the tumors within the breast with practical cases.  ...  In this paper, new model had been proposed applied on real experimental elastography images. These images were for different cases of breast cancers (benign and malignant).  ...  We can consider that models as a software phantoms that can be used studying the effects and helping in accurate classification of breast cancer.  ... 
doi:10.4172/2254-609x.100084 fatcat:4kvsdi3bovfr3jzus22z3krawy

A Regression Model for Predicting Shape Deformation after Breast Conserving Surgery

Hooshiar Zolfagharnasab, Sílvia Bessa, Sara Oliveira, Pedro Faria, João Teixeira, Jaime Cardoso, Hélder Oliveira
2018 Sensors  
Breast cancer treatments can have a negative impact on breast aesthetics, in case when surgery is intended to intersect tumor.  ...  The simulator relies on a coupled multiscale Finite Element (FE) numerical procedure to solve two mathematical models: a biochemical model for wound healing and angiogenesis, and a biomechanical model  ...  Ciência e a Tecnologia (FCT) within Ph.D. grant number SFRH/BD/97698/2013 and SFRH/BD/115616/2016.  ... 
doi:10.3390/s18010167 pmid:29315279 pmcid:PMC5795402 fatcat:iimb4lwuuvf57mvvjqqvppfqli
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