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Comparison of IR- and UV-matrix-assisted laser desorption/ionization mass spectrometry of oligodeoxynucleotides

E. Nordhoff, F. Kirpekar, M. Karas, R. Cramer, S. Hahner, F. Hillenkamp, K. Kristiansen, P. Roepstorff, A. Lezius
1994 Nucleic Acids Research  
UV-matrix assisted laser desorption/ionization mass spectrometry (UV-MALDI-MS) with 3-hydroxypicolinic acid as matrix and IR-MALDI-MS with succinic acid as matrix have proved their feasibility for highly  ...  In this work, a detailed comparison of these two MALDI-methods and between positive-and negative ion mass spectra for the analysis of oligodeoxynucleotides is undertaken.  ...  ACKNOWLEDGEMENTS Part of this work was done in partial fulfilment of the requirement for the pH. D. degree of the author at the University of Miinster.  ... 
doi:10.1093/nar/22.13.2460 pmid:8041606 pmcid:PMC308196 fatcat:7flsb6mwfnd4jodtmslo6x3l5q

Direct mass spectrometric sequencing of low-picomole amounts of oligodeoxynucleotides with up to 21 bases by matrix-assisted laser desorption/ionization mass spectrometry

E. Nordhoff, M. Karas, R. Cramer, S. Hahner, F. Hillenkamp, F. Kirpekar, A. Lezius, J. Muth, C. Meier, J. W. Engels
1995 Journal of Mass Spectrometry  
Engels Institute of Organic Chemistry, University of Frankfurt, Niederurseler Hang, 60139 Frankfurt, Germany UV and IR matrix-assisted laser desorption/ionization mass spectrometry (UV- and IR-MALDI) have  ...  JOURNAL OF MASS SPECTROMETRY, VOL. 30, 99-112 (1995) Direct Mass Spectrometric Sequencing of Low-picomole Amounts of Oligodeoxynucleotides with up to 21 Bases by Matrix-assisted Laser Desorption/Ionization  ... 
doi:10.1002/jms.1190300116 fatcat:fry67ykzgfa4japygucyqjgqea

Ion stability of nucleic acids in infrared matrix-assisted laser desorption/ionization mass spectrometry

E. Nordhoff, R. Cramer, M. Karas, F. Hillenkamp, F. Kirpekar, K. Kristiansen, P. Roepstorff
1993 Nucleic Acids Research  
Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) with infrared laser light of a wavelength of 2.94 zm has been used for the analysis of nucleic acids.  ...  Technical details of the method, including the distribution of positive counterions on the phosphodiester backbone, the upper mass limit and mass accuracy are discussed along with a number of potential  ...  INTRODUCTION Whereas the matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has found broad applications for the analysis of oligopeptides and proteins' -6, investigations on nucleic  ... 
doi:10.1093/nar/21.15.3347 pmid:7688451 pmcid:PMC331430 fatcat:exbemggbknh7bdh3dhhtw67ofu

Ionic Liquid-Assisted Laser Desorption/Ionization–Mass Spectrometry: Matrices, Microextraction, and Separation

Hani Nasser Abdelhamid
2018 Methods and Protocols  
Ionic liquids (ILs) have advanced a variety of applications, including matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS).  ...  ILs can be used as matrices and solvents for analyte extraction and separation prior to analysis using laser desorption/ionization-mass spectrometry (LDI-MS).  ...  Ahmed Abdu Ahmed Abdel-Hafez geaies, president of Assuit University for his support. Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/mps1020023 pmid:31164566 pmcid:PMC6526421 fatcat:bvfbyjf72rhutn2grkeyylhok4

Index

1998 Journal of the American Society for Mass Spectrometry  
Matrix-assisted filament desorption/ionization mass spectrome- try, 1226 Matrix-assisted laser desorption/ionization of biomolecules, matrix solutions for, 166 near-UV-induced, as function of wavelength  ...  , 885 Matrix-assisted laser desorption/ionization-collision-induced dissociation, of poly(styrene), 269 Matrix-assisted laser desorption/ionization-mass spectrometry of acidic glycoconjugates facilitated  ... 
doi:10.1016/s1044-0305(98)00123-8 fatcat:3f3vgs4gc5cctetljqtncuozqm

Cumulative Subject Index, Volumes 1–20

2009 Journal of the American Society for Mass Spectrometry  
See Matrix-assisted laser desorption/ionization mass spectrometry; Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS); Matrix-assisted laser desorption/ionization-MS MALDI-MS/MS.  ...  mass accuracy in, 5:955 Matrix-assisted laser desorption ionization time-of-flight mass spectrometry of underivatized and permethylated gangliosides, 3:785 Matrix-assisted laser desorption/ionization  ...  , 15: 725 Matrix-assisted laser desorption/ionization tandem reflectron time-of-flight mass spectrometry of fullerenes, 7:590 Matrix-assisted laser desorption/ionization tandem time-offlight (MALDI-TOF  ... 
doi:10.1016/s1044-0305(09)00878-2 fatcat:farqphcssjfhdapopxo6mkezqq

Cumulative Subject index

2005 Journal of the American Society for Mass Spectrometry  
See Matrix-assisted laser desorption/ionization mass spectrometry; Matrix-assisted laser desorption/ion- ization mass spectrometry (MALDI-MS).; Matrix-assisted laser desorption/ionization-MS MALDI-ization  ...  Matrix-assisted laser desorption ionization time-of-flight mass spectrometry of underivatized and permethylated gangliosides, 3:785 Matrix-assisted laser desorption ionization-Fourier transform mass spectrometry  ...  , 4:882 mass spectrometry and tandem mass spectrometry analysis of, Optimization of capillary zone electrophoresis/electrospray ionization parameters for, 3:289 matrix-assisted laser desorption/ionization  ... 
doi:10.1016/s1044-0305(05)00972-4 fatcat:pl3tpqu2mrbj7iygyc64nzliui

Current literature in mass spectrometry

1995 Journal of Mass Spectrometry  
Riverside, Dept Chem, Riverside, Ca 92521, USA J Mass Spectrometry 1995 30 (1) 94 Recovery of peptides and proteins following matrix-assisted laser desorption/ ionization mass spectrometry Cerpa-Poljak  ...  processes in matrix-assisted laser desorption/ionization mass spec- trometry: Matrix-dependent formation of [M + H]* vs [M + Na]* ions of small peptides and some mechanistic comments Liao PC, Allison  ... 
doi:10.1002/jms.1190300718 fatcat:b7jl2leg7jhvllujtu3h5lfawm

Current literature in mass spectrometry

2002 Journal of Mass Spectrometry  
Campusvej 55, DK-5230 Odense M, Denmark Protein Sci 2001 10 (10) 1989 Determination of photomodified oligodeoxynucleotides by exonuclease diges- tion, matrix-assisted laser desorption/ionization mass spectrometry  ...  Taiwan Electrophoresis 2001 22 (18) 3972 Disposable polymeric high-density nanovial arrays for matrix assisted laser desorption/ionization-time of flight-mass spectrometry: II.  ... 
doi:10.1002/jms.249 pmid:11857770 fatcat:3zpmqq475fbdvjpriorujpjdim

Current literature in mass spectrometry

1995 Journal of Mass Spectrometry  
6, D-64289 Germany J Chromatogr A 1995 699 (1-2) 21 Matrix-assisted laser desorption/ionization mass spectrometry of synthetic polymers II.  ...  by matrix-assisted laser desorp- tion/ionization time of flight mass spectrometry.  ... 
doi:10.1002/jms.1190300922 fatcat:4gl4konyvraotifpwu5t4bpiji

Current literature in mass spectrometry

2002 Journal of Mass Spectrometry  
2002 13 (2) 187 One-way hydrophobic surface foil for UV matrix-assisted laser desorption/ ionization mass spectrometry of peptides (Letter) Rechthaler J, Allmaier G*// *Univ Vienna, Inst Analyt Chem,  ...  Greifswald, Germany Int J Mass Spectrom 2002 214 (3) 365 Measurement of mean initial velocities of analyte and matrix tons in infrared matrix-assisted laser desorption/ionization mass spectrometry Berkenkamp  ... 
doi:10.1002/jms.254 pmid:12125010 fatcat:ktxbdcm55fdpvhpmjtbt72lkmm

Current literature in mass spectrometry

2002 Journal of Mass Spectrometry  
of matrix-assisted laser desorption ionization-time of flight mass spectrometry and molecular cloning for the identification and functional char acterization of mobile orthohalobenzoate oxygenase genes  ...  , Mass Spectrometry Lab, Milan, Italy Anal Biochem 2001 298 (2) 181 Structure of the Bacillus subtilis peptide antibiotic subtilosin a determined by H-NMR and matrix assisted laser desorption/ionization  ... 
doi:10.1002/jms.251 pmid:11948851 fatcat:lxaj6ew7hvgt3iluxdrhmkahna

Current Literature in Journal of Mass Spectrometry

2003 Journal of Mass Spectrometry  
A 2002 974 (1-2) 103 Characterization of poly(butylene terephthalate) by size-exclusion chromatog raphy and matrix-assisted laser desorption/ionization time-of-flight mass spec trometry Lou XW, Van Dongen  ...  , Exhibition Rd, London SW7, England J Chromatogr A 2002 976 (1-2) 11 4 modified thermal deposition unit for gel-permeation chromatography with matrix-assisted laser desorption/ionization and electrospray  ... 
doi:10.1002/jms.418 pmid:12644999 fatcat:nbty2amlrbaoro3giipv4lpqmu

Tandem mass spectrometry for characterization of covalent adducts of DNA with anticancer therapeutics

Catherine Silvestri, Jennifer S. Brodbelt
2012 Mass spectrometry reviews (Print)  
This review focuses on the array of tandem mass spectrometric strategies developed and applied for characterization of covalent adducts formed between DNA and anticancer ligands.  ...  the nature of the resulting DNA adducts and provide insight into the mechanistic pathways of the DNA/drug interactions and the impact on the cellular processes in biological systems.  ...  Maldi Matrix assisted laser desorption ionization (MALDI), a method utilizing a pulsed laser to desorb molecule co-crystallized with a large excess of an absorbing matrix, was reported by Hillenkamp et  ... 
doi:10.1002/mas.21363 pmid:23150278 pmcid:PMC3578003 fatcat:atcsaj4ekrgfncqali2ryggdda

Intermolecular 'cross-torque': the N4-cytosine propargyl residue is rotated to the 'CH'-edge as a result of Watson-Crick interaction

O. Domingo, I. Hellmuth, A. Jaschke, C. Kreutz, M. Helm
2015 Nucleic Acids Research  
In oligodeoxynucleotides, however, UV-melting indicated that N 4 -propargyldeoxycytidine undergoes standard base pairing.  ...  ROESY-NMR experiments suggest a uniform orientation toward the Watson-Crick face of N 4 -propargyl residues in derivatives of both deoxycytidine and 5-methyl-deoxycytidine.  ...  The authors would like to thank Mr Heiko Rudy at the IPMB (University of Nucleic Acids Research, 2015, Vol. 43, No. 11 5283 Heidelberg) for MALDI-TOF measurements of the synthesized oligonucleotides  ... 
doi:10.1093/nar/gkv285 pmid:25934805 pmcid:PMC4477647 fatcat:zhui7in2drgv5lqjt7dln6njre
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