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Comparative Visualization for Diffusion Tensor Imaging Group Study at Multiple Levels of Detail [article]

Changgong Zhang, Thomas Höllt, Matthan W. A. Caan, Elmar Eisemann, Anna Vilanova
2017 Eurographics Workshop on Visual Computing for Biomedicine  
[ZCH 17] to visually compare two groups of diffusion tensor fields. To deal with the wealth of information, the comparison is carried out at multiple levels of detail.  ...  Diffusion Tensor Imaging (DTI) group studies often require the comparison of two groups of 3D diffusion tensor fields.  ...  Acknowledgements We gratefully acknowledge the Co-morbidity in relation to Aids (COBRA) project for providing the DTI datasets that are used in Section 4.  ... 
doi:10.2312/vcbm.20171237 dblp:conf/vcbm/ZhangHCEV17 fatcat:n3zmuw3m4jcpdo3ly5u7zf67yu

Diffusion tensor magnetic resonance imaging for single subject diagnosis in neurodegenerative diseases

Seyed A. Sajjadi, Julio Acosta-Cabronero, Karalyn Patterson, Lara Z. Diaz-de-Grenu, Guy B. Williams, Peter J. Nestor
2013 Brain  
This report presents evidence to indicate that corticobasal degeneration and progressive supranuclear palsy, in particular, might be identifiable at a single subject level with diffusion tensor imaging  ...  grey matter analysis consisting of group level voxel-based morphometry revealed only focal areas of atrophy in all three groups.  ...  can be visualized at the level of the individual.  ... 
doi:10.1093/brain/awt118 pmid:23729473 fatcat:2t5y4udbfng3bc5f24ffk53vcq

Effect of Increasing Diffusion Gradient Direction Number on Diffusion Tensor Imaging Fiber Tracking in the Human Brain

Xufeng Yao, Tonggang Yu, Beibei Liang, Tian Xia, Qinming Huang, Songlin Zhuang
2015 Korean Journal of Radiology  
measured for the splenium of the CC at the tract branch level, for the entire CC at tract level, and for the full brain tract at the whole brain level.  ...  Materials and Methods: Twelve normal volunteers underwent diffusion tensor imaging (DTI) scanning with NDGDs of 6, 11, 15, 21, and 31 orientations.  ...  Ning Jiang for the explanation of the statistical analyses implemented in our paper.  ... 
doi:10.3348/kjr.2015.16.2.410 pmid:25741203 pmcid:PMC4347277 fatcat:jqvci6rr2nbqdevq7boiqsw5m4

Visual Analytics of Group Differences in Tensor Fields: Application to Clinical DTI [article]

Amin Abbasloo, Vitalis Wiens, Tobias Schmidt-Wilcke, Pia Sundgren, Reinhard Klein, Thomas Schultz
2017 arXiv   pre-print
A mechanism for visually comparing the results of different tests or levels of smoothing is also provided.  ...  In close collaboration with our clinical co-authors, we apply it to the results of a diffusion tensor imaging study of systemic lupus erythematosus, in which it revealed previously unknown group differences  ...  this encoding and combined it with complementary visualizations to enable visualization of tensor field ensembles [11] , as well as a visual comparison of groups of tensor fields at multiple levels of  ... 
arXiv:1711.08279v1 fatcat:nflvf3hqbzckpjg6npw4ejkbri

Interactive Formation of Statistical Hypotheses in Diffusion Tensor Imaging

Amin Abbasloo, Vitalis Wiens, Tobias Schmidt-Wilcke, Pia Sundgren, Reinhard Klein, Thomas Schultz
2019 Eurographics Workshop on Visual Computing for Biomedicine  
When Diffusion Tensor Imaging (DTI) is used in clinical studies, statistical hypothesis testing is the standard approach to establish significant differences between groups, such as patients and healthy  ...  Therefore, we introduce a test that can be customized to include any subset of tensor attributes that are relevant to the analysis task at hand.  ...  [ZCH * 17], as well as a visual comparison of groups of tensor fields at multiple levels of detail [ZHC * 17].  ... 
doi:10.2312/vcbm.20191229 dblp:conf/vcbm/AbbaslooWSSK019 fatcat:t2bmtyhh3rfczawdp262boztu4

Stability of white matter changes related to Huntington's disease in the presence of imaging noise: a DTI study

Hans-Peter Müller, Volkmar Glauche, Marianne J U Novak, Thao Nguyen-Thanh, Alexander Unrath, Nayana Lahiri, Joy Read, Miranda Julia Say, Sarah J Tabrizi, Jan Kassubek, Stefan Kloppel
2011 PLOS Currents  
imaging (MRI) data and how post hoc compensation for it affects the MRI results.  ...  imaging (MRI) data and how post hoc compensation for it affects the MRI results.  ...  Acknowledgements The authors wish to extend their gratitude to the London TRACK-HD study participants and to Beth Borowsky, scientific director for TRACK-HD at CHDI.  ... 
doi:10.1371/currents.rrn1232 pmid:21686312 pmcid:PMC3111746 fatcat:ddl3eqrewne77j3pfmlr7lu5ui

White matter pathways in reading

Michal Ben-Shachar, Robert F Dougherty, Brian A Wandell
2007 Current Opinion in Neurobiology  
In the past few years, diffusion tensor imaging has been used to identify correlations between white matter properties and reading skills in adults and children.  ...  Skilled reading requires mapping of visual text to sound and meaning.  ...  Acknowledgements This work was supported by NIH grant EY015000 and by the Schwab Foundation for Learning. We are grateful to Professor Ugur Tü re for providing the dissection image in Figure 1a .  ... 
doi:10.1016/j.conb.2007.03.006 pmid:17379499 fatcat:3mlx55anjzbz5nf3fetddrjriu

Diffusion Tensor Magnetic Resonance Imaging and Fiber Tractography of the Sacral Plexus in Children with Spina Bifida

Wieke Haakma, Pieter Dik, Bennie ten Haken, Martijn Froeling, Rutger A.J. Nievelstein, Inge Cuppen, Tom P.V.M. de Jong, Alexander Leemans
2014 Journal of Urology  
Conclusions: To our knowledge this 3 Tesla magnetic resonance imaging study showed for the first time sacral plexus asymmetry and disorganization in 10 patients with spina bifida using diffusion tensor  ...  We investigated anatomical and microstructural properties of the sacral plexus of patients with spina bifida using diffusion tensor imaging and fiber tractography.  ...  ACKNOWLEDGMENTS Niels Blanken, Department of Radiology, assisted with acquiring MRI data.  ... 
doi:10.1016/j.juro.2014.02.2581 pmid:24769033 fatcat:yal2yxrdczgh5mdj6dqnwmpxf4

Longitudinal Brain White Matter Alterations in Minimal Hepatic Encephalopathy before and after Liver Transplantation

Wei-Che Lin, Kun-Hsien Chou, Chao-Long Chen, Hsiu-Ling Chen, Cheng-Hsien Lu, Shau-Hsuan Li, Chu-Chung Huang, Ching-Po Lin, Yu-Fan Cheng, Elizabeth J. Coulson
2014 PLoS ONE  
Improved pre-transplantation albumin levels and interval changes were associated with better recoveries of diffusion tensor imaging indices.  ...  In conclusion, longitudinal voxel-wise analysis of multiple diffusion tensor imaging indices demonstrated different white matter changes in minimal hepatic encephalopathy patients.  ...  Contributed to the writing of the manuscript: WCL CPL YFC.  ... 
doi:10.1371/journal.pone.0105887 pmid:25166619 pmcid:PMC4148329 fatcat:bwo2ayn4unaunhpqjrpimgyhae

Merged Group Tractography Evaluation with Selective Automated Group Integrated Tractography

David Q. Chen, Jidan Zhong, David J. Hayes, Brendan Behan, Matthew Walker, Peter S.-P. Hung, Mojgan Hodaie
2016 Frontiers in Neuroanatomy  
We use a merged tractography approach that permits evaluation of tractography datasets at the group level.  ...  We propose Selective Automated Group Integrated Tractography (SAGIT), an automated group tractography software platform that incorporates multiple diffusion magnetic resonance imaging (dMRI) practices  ...  In the classic single-tensor dMRI (also known as diffusion tensor image; DTI) model (Basser and Jones, 2002) , a single tensor is constructed at each voxel based on Gaussian model of diffusion, which  ... 
doi:10.3389/fnana.2016.00096 pmid:27790095 pmcid:PMC5061742 fatcat:gk2e3y3p2bf6rc2aaqebhfq7wi

Diffusion MRI abnormalities detection with orientation distribution functions: A multiple sclerosis longitudinal study

Olivier Commowick, Adil Maarouf, Jean-Christophe Ferré, Jean-Philippe Ranjeva, Gilles Edan, Christian Barillot
2015 Medical Image Analysis  
We propose a new algorithm for the voxelwise analysis of orientation distribution functions between one image and a group of reference images.  ...  We demonstrate that this method, combined to dimensionality reduction through a principal component analysis, allows for more robust detection of lesions on simulated data when compared to classical tensor-based  ...  Acknowledgments The authors acknowledge Neurinfo MRI research facility for logistic support and MRI data acquisition.  ... 
doi:10.1016/j.media.2015.02.005 pmid:25867549 fatcat:yxbmnjbfcredrmevvfs56sdysa

Fluid Registration of Diffusion Tensor Images Using Information Theory

Ming-Chang Chiang, A.D. Leow, A.D. Klunder, R.A. Dutton, M. Barysheva, S.E. Rose, K.L. McMahon, G.I. de Zubicaray, A.W. Toga, P.M. Thompson
2008 IEEE Transactions on Medical Imaging  
We apply an information-theoretic cost metric, the symmetrized Kullback-Leibler (sKL) divergence, or -divergence, to fluid registration of diffusion tensor images.  ...  Index Terms-Diffusion tensor imaging (DTI), fluid registration, high angular resolution diffusion imaging (HARDI), Kullback-Leibler divergence.  ...  These images were acquired as part of a previous study where subject demographics are detailed [45] .  ... 
doi:10.1109/tmi.2007.907326 pmid:18390342 pmcid:PMC2770435 fatcat:mqa7opljn5cv7kmcuvakdg4tji

Imaging Surrogates of Disease Activity in Neuromyelitis Optica Allow Distinction from Multiple Sclerosis

Lucy Matthews, Shannon Kolind, Alix Brazier, Maria Isabel Leite, Jonathan Brooks, Anthony Traboulsee, Mark Jenkinson, Heidi Johansen-Berg, Jacqueline Palace, Monika Bradl
2015 PLoS ONE  
To investigate this we conducted a longitudinal advanced MRI study of the brain and spinal cord in neuromyelitis optica patients, comparing to patients with multiple sclerosis and controls.  ...  We found both cross-sectional and longitudinal evidence of diffusely distributed neurodegenerative surrogates in the multiple sclerosis group (including thalamic atrophy, cervical cord atrophy and progressive  ...  Thank you to our support staff at the John Radcliffe Hospital and Nuffield Department of Clinical Neurosciences, University of Oxford, including the radiographers and specialist nurses.  ... 
doi:10.1371/journal.pone.0137715 pmid:26381510 pmcid:PMC4575169 fatcat:2rlw4jalfbgrtgy7nxzzpv22wa

Abnormal diffusion of cerebral white matter in early blindness

Ni Shu, Jun Li, Kuncheng Li, Chunshui Yu, Tianzi Jiang
2009 Human Brain Mapping  
Such secondary changes in the gray matter of the early blind have been well studied, but not so well in the cerebral white matter whose subtle changes may be revealed by diffusion tensor imaging.  ...  Then we studied the changes of mean diffusivity (MD), FA, primary (k 1 ) and transverse diffusivities (k 23 ) in the GCT using tractography based group mapping analysis.  ...  The significance was determined with a P < 0.05 (corrected for multiple comparisons at the cluster level). Similarly, TBSS analyses of MD, k 1 and k 23 images were performed, respectively.  ... 
doi:10.1002/hbm.20507 pmid:18072278 fatcat:ehsmamk6hre5nk4xt3zeaujj3a

A Predictive Visual Analytics System for Studying Neurodegenerative Disease based on DTI Fiber Tracts [article]

Chaoqing Xu, Tyson Neuroth, Takanori Fujiwara, Ronghua Liang, Kwan-Liu Ma
2021 arXiv   pre-print
Diffusion tensor imaging (DTI) has been used to study the effects of neurodegenerative diseases on neural pathways, which may lead to more reliable and early diagnosis of these diseases as well as a better  ...  We introduce an intelligent visual analytics system for studying patient groups based on their labeled DTI fiber tract data and corresponding statistics.  ...  Pauline Maillard from the Department of Neurology, the University of California at Davis, Dr.  ... 
arXiv:2010.07047v4 fatcat:qbkegb3uxbdpzmq2656ee6p6u4
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