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Computer-Interpretable Guideline formalisms

Paul De Clercq, Katharina Kaiser, Arie Hasman
2008 Studies in Health Technology and Informatics  
Implementing Computer-Interpretable Guidelines (CIGs) in active computer-based decision support systems promises to improve the acceptance and application of guidelines in daily practice.  ...  This aim of this chapter is to provide an overview of well-known approaches and to formulate a set of (minimal) requirements that can be used in the process of developing new CIG approaches or improving  ...  The model must support these types of knowledge and should model them separately to support guideline sharing and to ensure that guidelines can be used in multiple clinical domains and in various modes  ... 
pmid:18806319 pmcid:PMC2858861 fatcat:mrlonzjiefbtxm5nxmzcbfgh3u

Modeling Clinical Guidelines through Petri Nets [chapter]

Marco Beccuti, Alessio Bottrighi, Giuliana Franceschinis, Stefania Montani, Paolo Terenziani
2009 Lecture Notes in Computer Science  
Clinical guidelines (GLs) play an important role to standardize and organize clinical processes according to evidence-based medicine.  ...  Several computer-based GL representation languages have been defined, usually focusing on expressiveness and/or on user-friendliness.  ...  In the future, we plan to investigate PN-based GL verification as well, and to complete the integration (and testing) of our approach within the GLARE system.  ... 
doi:10.1007/978-3-642-02976-9_8 fatcat:rnk2oh23v5fy7hawtniajekrgu

Webifying the Computerized Execution of Clinical Practice Guidelines [chapter]

Tiago Oliveira, Pedro Leão, Paulo Novais, José Neves
2014 Advances in Intelligent Systems and Computing  
Making these guidelines available in Clinical Decision Support Systems renders their application more personal and thus acceptable at the moment of care.  ...  The means through which Clinical Practice Guidelines are disseminated and become accessible are a crucial factor in their later adoption by health care professionals.  ...  para a Ciência e a Tecnologia (Portuguese Foundation for Science and Technology) within project FCOMP-01-0124-FEDER-028980 (PTDC/EEI-SII/1386/2012).  ... 
doi:10.1007/978-3-319-07476-4_18 fatcat:vrxth5ayufcstaba35fzo4rtsy

Visualization methods to support guideline-based care management

Wolfgang Aigner, Katharina Kaiser, Silvia Miksch
2008 Studies in Health Technology and Informatics  
Furthermore, to analyze the effectiveness and usefulness of clinical guidelines they need to be shown in connection with the patients' data.  ...  In this overview book chapter we present different methods to visualize clinical guidelines, patients' data, and the connection thereof.  ...  Clinical Algorithm Maps- The most widely used visual representation of clinical guidelines are so-called flowchart algorithms, also known as clinical algorithm maps [9] .  ... 
pmid:18806325 pmcid:PMC2858819 fatcat:fce6ykb3hfdnbpj4dd7qqzlbxu

Representing Clinical Guidelines in GLIF: Individual and Collaborative Expertise

V. L. Patel, V. G. Allen, J. F. Arocha, E. H. Shortliffe
1998 JAMIA Journal of the American Medical Informatics Association  
Objective: An evaluation of the cognitive processes used in the translation of a text clinical guideline into an encoded form so that it can be shared among medical institutions.  ...  Measurements: Using theories and methods of cognitive science, the present study involves a detailed analysis of the cognitive processes used in generating representations in GLIF.  ...  This paper has greatly benefited from the critical comments of Jim Cimino and two anonymous reviewers of earlier versions of the manuscript.  ... 
doi:10.1136/jamia.1998.0050467 pmid:9760394 pmcid:PMC61328 fatcat:kh2rkzx66vdflfzq4uub774hjm

What's nice about the new NICE guideline?

J. O'Reilly, M. Rudolf
2010 Thorax  
secondary care and patient representation.  ...  It is good to see that the new NICE guideline now agrees with other international guidelines both in recommending the use of postbronchodilator spirometry for confirmation of diagnosis and also in using  ...  Competing interests Both authors were members of the Guideline Development Group for the NICE guideline (JO'R the Clinical Advisor and MR the Chair).  ... 
doi:10.1136/thx.2010.144451 pmid:21097818 fatcat:jifix4y7q5f5jelyqnd7tdnifa

The Role of Ontologies for an Effective and Unambiguous Dissemination of Clinical Guidelines [chapter]

Domenico M. Pisanelli, Aldo Gangemi, Geri Steve
2000 Lecture Notes in Computer Science  
Guidelines for clinical practice are being introduced in an extensive way in more and more different fields of medicine They have the potential to improve the quality and cost-efficiency of care in a complex  ...  In this paper we present our library of generic and domain ontologies and point out its role for integrating existing guideline models and defining standard representations.  ...  "Clinical activities" is one ontology included by "guidelines", meaning that its concepts and relationships are used by the former one.  ... 
doi:10.1007/3-540-39967-4_10 fatcat:cpijteirsrcdhfdzpuonncvmke

Incremental guideline formalization with tool support [chapter]

Radu Serban, Anna Puig-Centelles, Annette ten Teije
2006 IFIP International Federation for Information Processing  
Guideline formalization is recognized as an important component in improving computerized guidelines, which in turn leads to better informedness, lower inter-practician variability and, ultimately, to  ...  We give a general evaluation of usefulness and state the main requirements for tools that reuse medical knowledge and support authoring of guidelines.  ...  Conclusions We compared the implementations of two knowledge transformation principles for guideline formalization, embodied by two of the very few tools that can be used in practice for improving the  ... 
doi:10.1007/0-387-34224-9_13 fatcat:bumccnxxuba7blsno4zbioropm

Using OWL Ontologies for Clinical Guidelines Based Comorbid Decision Support

Samina Abidi, Jafna Cox, Michael Shepherd, S. Sibte Raza Abidi
2012 2012 45th Hawaii International Conference on System Sciences  
In this paper we present an ontology-based clinical decision-support framework for handling comorbidities by alignment of ontology modeled clinical practice guidelines (CPG).  ...  sources; (b) knowledge modeling to abstract medical and procedural knowledge from the CP; (c) knowledge representation to computerize the CP in terms of a CP ontology; and (d) knowledge alignment by aligning  ...  The application of evidencebased Clinical Practice Guidelines (CPG) and clinical pathways (CP), at the point-of-care has the potential to reduce this care gap.  ... 
doi:10.1109/hicss.2012.629 dblp:conf/hicss/AbidiCAS12 fatcat:wsoiewwbrzdqpnlekloixthvea

Approaches for creating computer-interpretable guidelines that facilitate decision support

Paul A de Clercq, Johannes A Blom, Hendrikus H.M Korsten, Arie Hasman
2004 Artificial Intelligence in Medicine  
This slot may hold the values 'testing', 'research' (approved for clinical research), 'production' (approved for clinical care) and 'expired' (no longer in use).  ...  Various studies, covering a wide range of clinical settings and tasks, concluded that the use of these systems significantly improves the quality of care, especially when used in combination with clinical  ... 
doi:10.1016/j.artmed.2004.02.003 pmid:15182844 fatcat:lmjpz4wmqfcmflkuaieleupdeu

Free and open source enabling technologies for patient-centric, guideline-based clinical decision support: a survey

T Y Leong, K Kaiser, S Miksch
2007 IMIA Yearbook of Medical Informatics  
In this paper, we survey the current FOS enabling technologies for patient-centric, guideline-based care, and discuss the current trends and future directions of their role in clinical decision support  ...  We searched PubMed, major biomedical informatics websites, and the web in general for papers and links related to FOS health care IT systems.  ...  in health care IT and clinical decision support solutions [9, 12] .  ... 
pmid:17700908 pmcid:PMC2858818 fatcat:fkc77mkr6bgztgeadhaacxekta

Efficient management of multi-version clinical guidelines

Fabio Grandi, Federica Mandreoli, Riccardo Martoglia
2012 Journal of Biomedical Informatics  
Clinical medicine and health-care developments in recent years testified a tremendous increase in the number of available guidelines, i.e., "best practices" encoding and standardizing care procedures for  ...  In this work, we will introduce techniques to model and to provide efficient personalized access to very large collections of multi-version clinical guidelines, which can be stored both in textual and  ...  In other words, clinical guidelines are best practices encoding and standardizing care procedures for a given disease [2] .  ... 
doi:10.1016/j.jbi.2012.07.005 pmid:22890019 fatcat:drztcy3zsncxfaawq35sukby6m

Use of medical informatics to implement and develop clinical practice guidelines

D K Owens
1998 Western Journal of Medicine  
Clinical practice guidelines have enormous potential to improve the quality of and accountability in health care.  ...  In addition, using decision models to produce guidelines enables developers to structure guideline problems systematically, to prioritize information acquisition, to develop site-specific guidelines, and  ...  Cody, and Lyn Dupre for comments on the manuscript; and Andria Cardinalli for help with background research.  ... 
pmid:9549415 pmcid:PMC1304856 fatcat:epc5yacg6fhlxkca36ntfqhulm

Zinc transporter Slc39a8 is essential for cardiac ventricular compaction

Wen Lin, Deqiang Li, Lan Cheng, Li Li, Feiyan Liu, Nicholas J. Hand, Jonathan A. Epstein, Daniel J. Rader
2018 Journal of Clinical Investigation  
The extracellular matrix (ECM) that separates endocardium from myocardium plays a critical but poorly understood role in ventricular trabeculation and compaction.  ...  Here, we have shown that Slc39a8 is expressed by endothelial cells in the developing mouse heart, where it serves to maintain cellular Zn levels.  ...  We thank the Penn CVI Histology Core and the Flow Cytometry and Cell Sorting Resource Laboratory for technical assistance and the  ... 
doi:10.1172/jci96993 pmid:29337306 pmcid:PMC5785267 fatcat:i4bu36y7ebaonk5zehyijkm334

From Clinical Practice Guideline to Clinical Pathway –Issues of Reference Model-Based Approach [chapter]

Hannes Schlieter, Werner Esswein
2010 IFIP Advances in Information and Communication Technology  
In contrast, Clinical Practice Guidelines (CPGs) aggregate the evident medical knowledge in a compact form to support physicians in their practice.  ...  They allow to transfer evident knowledge in practice and they are the central point of clinical quality management.  ...  Comparison of Clinical Practice Guideline and Clinical Pathway The evaluation criteria that are used based on the concept definition.  ... 
doi:10.1007/978-3-642-15961-9_30 fatcat:a5yvu4tuybcj5ecudtykieeo3e
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