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Neurocircuity of Eating Disorders [chapter]

Walter H. Kaye, Angela Wagner, Julie L. Fudge, Martin Paulus
2010 Current topics in behavioral neurosciences  
The DPLFC can switch between competing behavioral programs based on the error signal it receives from the ACC (Kerns et al. 2004 ).  ...  In animals, DA modulates the influence of limbic inputs on striatal activity (Goto and Grace 2005; Montague et al. 2004; Schultz 2004; Yin and Knowlton 2006) and mediates the "binding" of hedonic evaluation  ... 
doi:10.1007/7854_2010_85 pmid:21243469 pmcid:PMC5957512 fatcat:4lp2kwurpvakfhdnjmjspqhwcm

Emotion and Decision Making: Multiple Modulatory Neural Circuits

Elizabeth A. Phelps, Karolina M. Lempert, Peter Sokol-Hessner
2014 Annual Review of Neuroscience  
Studies show two potential mechanisms for affect's modulation of the computation of subjective value and decisions.  ...  Although the prevalent view of emotion and decision making is derived from the notion that there are dual systems of emotion and reason, a modulatory relationship more accurately reflects the current research  ...  This work was partially funded by a grant from the National Institutes of Health (AG039283) to E.A.P. LITERATURE CITED  ... 
doi:10.1146/annurev-neuro-071013-014119 pmid:24905597 fatcat:7pplwpbfvzb3letzat65cf3qs4

Striatal direct and indirect pathways control decision-making behavior

Tom Macpherson, Makiko Morita, Takatoshi Hikida
2014 Frontiers in Psychology  
Despite our ever-changing environment, animals are remarkably adept at selecting courses of action that are predictive of optimal outcomes.  ...  Here we review current models of striatal-based decision-making, discuss recent developments in defining the functional roles of striatal output pathways, and assess how striatal dysfunction may contribute  ...  ACKNOWLEDGMENTS This work was supported by Grant-In-Aid for Scientific Research on Innovative Areas "Elucidation of the Neural Computation for Prediction and Decision Making" (23120011) and Grant-In-Aid  ... 
doi:10.3389/fpsyg.2014.01301 pmid:25429278 pmcid:PMC4228842 fatcat:bvqx6a7ee5azxkmhkuvhf4z6ue

The Roles of Dopamine and Serotonin in Decision Making: Evidence from Pharmacological Experiments in Humans

Robert D Rogers
2010 Neuropsychopharmacology  
Finally, I suggest that the role played by serotonin in the regulation of cognitive biases, and representation of context in learning, point toward a role in the cortically mediated cognitive appraisal  ...  of reinforcers when selecting between actions, potentially accounting for its influence upon the processing salient aversive outcomes and social choice.  ...  In addition, analysis of the magnitude of both BOLD signals associated with positive striatal prediction errors (increases in signal associated with the delivery of winning outcomes) and negative prediction  ... 
doi:10.1038/npp.2010.165 pmid:20881944 pmcid:PMC3055502 fatcat:krmzwdtswzhivist4ogscqudkm

Cognition-Emotion Dysinteraction in Schizophrenia

Alan Anticevic, Philip R. Corlett
2012 Frontiers in Psychology  
We focus on three research areas that highlight cognition-emotion dysinteractions in schizophrenia: First, we discuss the role of cognitive deficits in the "maintenance" of emotional information.  ...  We discuss these diverse domains of function from the perspective of disrupted neural circuits involved in "cold" cognitive vs. "hot" affective operations and the interplay between these processes.  ...  Its contents are solely the responsibility of the authors and do not necessarily represent the official view of NIH.  ... 
doi:10.3389/fpsyg.2012.00392 pmid:23091464 pmcid:PMC3470461 fatcat:mf5ciwlbebctzgiax2xkajjfbu

Nucleus accumbens and impulsivity

Koray Basar, Thibaut Sesia, Henk Groenewegen, Harry W.M. Steinbusch, Veerle Visser-Vandewalle, Yasin Temel
2010 Progress in Neurobiology  
These findings on the representation of prediction error support the contribution of the activity in the ventral striatum/NAc in outcome evaluation.  ...  The NAc functions as a key element of cortico-striatal circuits regulating cognitive and behavioral processes.  ... 
doi:10.1016/j.pneurobio.2010.08.007 pmid:20831892 fatcat:rshmp37qczd57iiinv3pqagjhi

Delta Opioid Receptors: Learning and Motivation [chapter]

L. P. Pellissier, C. N. Pujol, J. A. J. Becker, J. Le Merrer
2016 Handbook of Experimental Pharmacology  
In this review, we will focus on the involvement of delta opioid receptor in modulating different types of hippocampal-and striatal-dependent learning processes, as well as motor function, motivation and  ...  reward.Remarkably, DOR seems to play a key role in balancing hippocampal and striatal functions, with major implications for the control of cognitive performance and motor function under healthy and pathological  ...  We focused here on the involvement of this receptor in modulating learning and memory processes, motor function and reward/motivation, notably by regulating the balance between hippocampal and striatal  ... 
doi:10.1007/164_2016_89 pmid:28035528 fatcat:wclqerh3hvbgxlrknzvwupbvxe

Homeostatic regulation of memory systems and adaptive decisions

Sheri J.Y. Mizumori, Yong Sang Jo
2013 Hippocampus  
A homeostatic-regulated prediction model of memory is presented that considers the existence of a single memory system that is based on a multilevel coordinated and integrated network (from cells to neural  ...  systems) that determines the extent to which events and outcomes occur as predicted.  ...  Acknowledgments The authors thank Wambura Fobbs, Sujean Oh, Marsha Penner, Van Redila, and Valerie Tryon for early discussions of different segments of this article.  ... 
doi:10.1002/hipo.22176 pmid:23929788 pmcid:PMC4165303 fatcat:dedz2bmnj5agdgklpojwe3a7pq

A systematic review of fMRI reward paradigms used in studies of adolescents vs. adults: The impact of task design and implications for understanding neurodevelopment

Jessica M. Richards, Rista C. Plate, Monique Ernst
2013 Neuroscience and Biobehavioral Reviews  
The present review will examine task design as one source of variability across findings by compiling this literature along three dimensions: (1) task structures, (2) cognitive processes, and (3) neural  ...  influence these findings.  ...  In essence, these models describe a cognitive regulatory system that modulates the activity of an emotional/motivational system.  ... 
doi:10.1016/j.neubiorev.2013.03.004 pmid:23518270 pmcid:PMC3809756 fatcat:tey7ex5manduhnefdzwkidrq2e

Cortico-Striatal-Thalamic Loop Circuits of the Orbitofrontal Cortex: Promising Therapeutic Targets in Psychiatric Illness

Peter Fettes, Laura Schulze, Jonathan Downar
2017 Frontiers in Systems Neuroscience  
Frontiers in Systems Neuroscience | www.frontiersin.org FIGURE 1 | Structure of the cortico-striatal loops stemming from the orbitofrontal cortex (OFC) subregions.  ...  (A) Schematic showing the entire medial OFC (mOFC) cortico-striatal loop, originating from the mOFC shown in red.  ...  The lOFC is prominently active during the cognitive reappraisal of emotional stimuli (Wager et al., 2008) and the tracking of counterfactual incentive signals (reward fictive error; Boorman et al.,  ... 
doi:10.3389/fnsys.2017.00025 pmid:28496402 pmcid:PMC5406748 fatcat:nnyxkd6tungtnk2gvpohhbbyeu

Beyond Simple Models of Self-Control to Circuit-Based Accounts of Adolescent Behavior

B. J. Casey
2015 Annual Review of Psychology  
We present evidence that these alarming health statistics are in part due to diminished self-controlthe ability to inhibit inappropriate desires, emotions, and actions in favor of appropriate ones.  ...  Adolescence is the transition from childhood to adulthood that begins around the onset of puberty and ends with relative independence from the parent.  ...  (a) Proportion of false alarm errors to distractor smiling faces relative to calm faces by age. (b) Localization of ventral striatal activity to smiling faces on a representative axial image.  ... 
doi:10.1146/annurev-psych-010814-015156 pmid:25089362 fatcat:o5ptblwfandn5javgh4dtcrci4

Stress potentiates decision biases: A stress induced deliberation-to-intuition (SIDI) model

Rongjun Yu
2016 Neurobiology of Stress  
It is possible that stress influences the arbitration between the emotion responses in subcortical regions and deliberative processes in the prefrontal cortex, so that final decisions are based on unexamined  ...  , and predict that this switch is associated with diminished activity in the prefrontal executive control regions and exaggerated activity in subcortical reactive emotion brain areas.  ...  The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.  ... 
doi:10.1016/j.ynstr.2015.12.006 pmid:27981181 pmcid:PMC5146206 fatcat:h72qs6bonjfevd4empeffwrwi4

A Dynamic Affective Core to bind the Contents, Context, and Value of Conscious Experience [article]

Kenneth T. Kishida, L. Paul Sands
2021 bioRxiv   pre-print
This research is beginning to reveal an explicit connection between the dynamics of dopaminergic signals and dynamic changes in subjective affect.  ...  ' of explaining how subjective phenomenal experience can arise from neural activity but set it aside and focus on the 'easier' problems associated with information representation and behavior.  ...  Acknowledgements This work was supported by funding from the NIH. KTK was supported by the NIH-NIDA (R01-DA048096), NIH-NIMH (R01-MH121099), NIH-NINDS (R01-NS092701), and NIH-NCATS (KL2TR001421).  ... 
doi:10.1101/2021.05.20.444839 fatcat:pukizpozhbb3zbzn45gjggn3zi

Predictive Reward Signal of Dopamine Neurons

Wolfram Schultz
1998 Journal of Neurophysiology  
Thus dopamine neurons label environmental stimuli with appe-Despite their importance, rewards do not influence the brain titive value, predict and detect rewards and signal alerting and through dedicated  ...  processing them. as good as predicted, and are depressed by events that are worse One of the principal neuronal systems involved in prothan predicted.  ...  inputs i1-i4 replicate the actor input, and the divergent projection of dopamine neurons R on multiple spines of multiple striatal neurons o1-o3 replicates the global influence of the critic on the actor  ... 
doi:10.1152/jn.1998.80.1.1 pmid:9658025 fatcat:ou4ao2xyibabvgatpi3xyymxke

Age-related variability in decision-making: Insights from neurochemistry

Anne S. Berry, William J. Jagust, Ming Hsu
2018 Cognitive, Affective, & Behavioral Neuroscience  
In an effort to provide clarity to the field and advance productive hypothesis testing, we propose ways in which in vivo dopamine imaging can be leveraged to disambiguate dopaminergic influences on decision-making  ...  We propose that some of the conflicting findings in age-related effects on decision-making may be reconciled if we can observe the underlying dopamine components within individuals.  ...  This work was supported by National Institute on Aging Grants K99 AG058748 (A.S.B.) and R01 AG044292 (W.J.J.), National Science Foundation award BSC-0821855, and the Alzheimer's Association Research Fellowship  ... 
doi:10.3758/s13415-018-00678-9 pmid:30536205 pmcid:PMC6684213 fatcat:plxfp6d2yrb3phvryx754mceqi
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