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Conclusions: CodingMotif provides a theoretically and empirically-demonstrated advance for the detection of motifs overrepresented in coding sequences. ... These sequence motifs are expected to be overrepresented in nucleotide sequences bound by a common protein or small RNA. ... JHC was supported by National Science Foundation Award 0850155 as part of the American Recovery and Reinvestment Act. ...doi:10.1186/1471-2105-13-32 pmid:22333114 pmcid:PMC3298695 fatcat:ek7aej3b3remvgj3l6ket62fsm