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Clinical Validation of Single-Chamber Model-Based Algorithms Used to Estimate Respiratory Compliance [article]

Gregory Rehm, Jimmy Nguyen, Chelsea Gilbeau, Marc T Bomactao, Chen-Nee Chuah, Jason Adams
2021 arXiv   pre-print
Next, we use this data to evaluate 15 different algorithms that use the "single chamber" model of estimating respiratory compliance.  ...  Non-invasive estimation of respiratory physiology using computational algorithms promises to be a valuable technique for future clinicians to detect detrimental changes in patient pathophysiology.  ...  And finally, contributing respiratory therapists: Kenneth Ablog, Sarah Fonteno, Jonathan Lahola, Justin Griffiths, and Nazariy Siryy who assisted with the gathering of subject data and conducting end-inspiratory  ... 
arXiv:2109.10224v1 fatcat:kp7bfyyuz5h75f4dbhd4poyaeq

PEEP/ ARDSNet Scale Grouping of a Single Ventilator for Two Patients: Modeling Tidal Volume Response

Vitaly O Kheyfets, Steven R Lammers, Jennifer Wagner, Karsten Bartels, Jerome Piccoli, Bradford J Smith
2020 Respiratory care  
Using this model to perform a parametric study, we provide proof-of-concept for an algorithm to better match patients in different hypothetical scenarios of a single ventilator shared by > 1 patient.  ...  We emphasize that our results are currently based on a computational model that has not been validated against any preclinical or clinical data.  ...  This study was used to validate the current computational model. They reported that differences in lung compliance between simulated patients had a higher impact of V T inequality than resistance.  ... 
doi:10.4187/respcare.07931 pmid:32712582 pmcid:PMC7538006 fatcat:jqhldmpaffhr3bwr2sfxzvwn44

Use of a Single Ventilator to Support Multiple Patients: Modeling Tidal Volume Response to Heterogeneous Lung Mechanics [article]

Vitaly Oleg Kheyfets, Steven Lammers, Jennifer Wagner, Karsten Bartels, Bradford Smith
2020 medRxiv   pre-print
We emphasize that our results are currently based on a computational model that has not been validated against any pre-clinical/clinical data.  ...  Using this model to perform a parametric study, we provide proof-of-concept for an algorithm to better match patients in different hypothetical scenarios of a single ventilator shared by more than one  ...  Using this model to perform a parametric study, we provide proof-of-concept for an algorithm to better match patients in different hypothetical scenarios of a single ventilator shared by more than one  ... 
doi:10.1101/2020.04.07.20056671 fatcat:rrpm44h3w5dnri7vaxptuj266a

Human versus Computer Controlled Selection of Ventilator Settings: An Evaluation of Adaptive Support Ventilation and Mid-Frequency Ventilation

Eduardo Mireles-Cabodevila, Enrique Diaz-Guzman, Alejandro C. Arroliga, Robert L. Chatburn
2012 Critical Care Research and Practice  
A lung simulator programmed with each scenario's respiratory system characteristics was ventilated using the clinician, ASV, and MFV settings.Results.  ...  There are modes of mechanical ventilation that can select ventilator settings with computer controlled algorithms (targeting schemes).  ...  Acknowledgment No source of funding to report. Portions of this study were presented as an abstract/oral presentation at the CHEST meeting in Philadelphia, USA, in 2008.  ... 
doi:10.1155/2012/204314 pmid:23119152 pmcid:PMC3478732 fatcat:ssz6gkcykfh6rdg3lmulb4qohm

Computerised Analysis of Telemonitored Respiratory Sounds for Predicting Acute Exacerbations of COPD

Miguel Fernandez-Granero, Daniel Sanchez-Morillo, Antonio Leon-Jimenez
2015 Sensors  
In a 6-month pilot study, 16 patients with COPD were equipped with a home base-station and a sensor to daily record their respiratory sounds.  ...  This exploratory study aimed to evaluate the feasibility of using: (a) a respiratory sensor embedded in a self-tailored housing for ageing users; (b) a telehealth framework; (c) CARS and (d) machine learning  ...  The system detected seven out of 10 exacerbations. In the study of Yañez et al. [56] , a threshold-based algorithm that used home-based collected respiratory rate was assessed.  ... 
doi:10.3390/s151026978 pmid:26512667 pmcid:PMC4634495 fatcat:ccsrevzzjvdtdisp3sbhjqlvhy

Hemodynamic monitoring in thoracic surgical patients

Jacob Raphael, Lindsay A. Regali, Robert H. Thiele
2017 Current Opinion in Anaesthesiology  
Extravascular lung water measurements are well validated, predict postoperative lung function, but require the use of transpulmonary thermodilution.  ...  Understanding the scientific basis of these devices is the key to using them effectively. is to describe these advanced hemodynamic monitoring devices, with a particular focus on the underlying technology  ...  Financial support and sponsorship This work was supported by the Department of Anaesthesiology, University of Virginia, Charlottesville, VA, USA.  ... 
doi:10.1097/aco.0000000000000408 pmid:28030449 fatcat:pnz3k7xwjbffjeuvrelovlb6q4

Fractional-order impulse response of the respiratory system

Clara Ionescu, Jose Tenreiro Machado, Robin De Keyser
2011 Computers and Mathematics with Applications  
Fractional order (FO) models are identified on the measured impedance to quantify the respiratory mechanical properties.  ...  The results of the identified FO models for the respiratory admittance are presented by means of their average values for each group of patients.  ...  (A.1) This represents the first order equation in the motion-equation for a single compartment model of the respiratory system: a single balloon with compliance C on a pipeline with a resistance R.  ... 
doi:10.1016/j.camwa.2011.04.021 fatcat:s3gckszycvha7fzivfv6b6kksu

Cardiac MR: From Theory to Practice

Tevfik F. Ismail, Wendy Strugnell, Chiara Coletti, Maša Božić-Iven, Sebastian Weingärtner, Kerstin Hammernik, Teresa Correia, Thomas Küstner
2022 Frontiers in Cardiovascular Medicine  
However, diversity and complexity of imaging, reconstruction and analysis methods pose some limitations to the widespread use of CMR.  ...  The handling of respiratory and cardiac motion strategies as well as their integration into the reconstruction processes is showcased. (5) Recent advances on deep learning-based reconstructions for this  ...  ., identification of model overfitting. However, the validation data set is not used to update the model parameters of the network.  ... 
doi:10.3389/fcvm.2022.826283 pmid:35310962 pmcid:PMC8927633 fatcat:j3vd446nxnajvgajkhazwbvgia

Quantification of Lung Fibrosis and Emphysema in Mice Using Automated Micro-Computed Tomography

Ellen De Langhe, Greetje Vande Velde, Jeroen Hostens, Uwe Himmelreich, Benoit Nemery, Frank P. Luyten, Jeroen Vanoirbeek, Rik J. Lories, Martin R. J. Kolb
2012 PLoS ONE  
This study aimed to develop and validate such an automated micro-computed tomography analysis algorithm for quantification of aerated lung volume in mice; an indicator of pulmonary fibrosis and emphysema  ...  In vivo high-resolution micro-computed tomography allows for longitudinal image-based measurements in animal models of lung disease.  ...  Acknowledgments The authors are grateful to Prof. Ria Bogaerts (Experimental Radiotherapy, KU Leuven) for her help with radiation dosage measurements. Author Contributions  ... 
doi:10.1371/journal.pone.0043123 pmid:22912805 pmcid:PMC3418271 fatcat:cwkll2gzffgyhfoh2rewd5itne

Journal of clinical monitoring and computing 2014 end of year summary: respiration

D. S. Karbing, S. E. Rees, M. B. Jaffe
2015 Journal of clinical monitoring and computing  
In the paper, Baldoli et al. presented as proof of concept a single chamber implementation of the system, with which they performed three clinical simulation scenarios: spontaneous breathing, controlled  ...  The system consists of five chambers with variable volumes connected to a mechanical ventilator with individual sensor and individually controlled pistons to simulate different compliances and resistances  ... 
doi:10.1007/s10877-015-9676-9 pmid:25735264 fatcat:yr6jvqvl55b63ik6g5h7to3f6q

Burden of Occupationally Acquired Pulmonary Tuberculosis among Healthcare Workers in the USA: A Risk Analysis

Rachael M. Jones
2017 Annals of Work Exposures and Health  
) in the USA, and to estimate the impact of increased compliance with respiratory protection.  ...  We used a risk analysis approach, in which occupational exposures were modeled using a compartmental model of bacilli transport and fate, and infection risk was estimated using two dose-response (DR) functions  ...  The author has no conflicts of interest to declare relating to this article. The contents of the article, including any  ... 
doi:10.1093/annweh/wxw015 pmid:28395347 fatcat:zga7qf7vefaz3kemaxefsyof5q

Pulse waveform hemodynamic monitoring devices: recent advances and the place in goal-directed therapy in cardiac surgical patients

2016 Romanian Journal of Anaesthesia and Intensive Care  
According to the data from the three GDTrandomized control trials performed in cardiac surgery (using two types of APW techniques PiCCO and FloTrac/Vigileo), these devices did not demonstrate that they  ...  The technological advances have led to innovating calibrated or not, but minimally invasive and noninvasive devices based on arterial pressure waveform (APW) analysis.  ...  can be estimated using a sophisticated algorithm (based on gender, age, height, weight).  ... 
doi:10.21454/rjaic.7518.231.wvf pmid:28913477 pmcid:PMC5505364 fatcat:qf46nszgpvgpjmlyxjhreivhwm

Non-Contact Vital Sign Monitoring in the Clinic

Mauricio Villarroel, Joao Jorge, Chris Pugh, Lionel Tarassenko
2017 2017 12th IEEE International Conference on Automatic Face & Gesture Recognition (FG 2017)  
Using an off-the-shelf camera and standard ambient light, this thesis proposes data fusion algorithms to compute estimates of heart rate and respiratory rate, and also to detect changes in 2 in a real  ...  Using an off-the-shelf camera and standard ambient light, this thesis proposes data fusion algorithms to compute estimates of heart rate and respiratory rate, and also to detect changes in 2 in a real  ...  Chapter 8 Respiratory rate estimation using a video camera Introduction This chapter discusses the algorithms and methodology to estimate respiratory rate from the video camera used in the clinical study  ... 
doi:10.1109/fg.2017.43 dblp:conf/fgr/VillarroelJPT17 fatcat:n6gzfcfyondipcdkstic57blie

Reconstruction techniques for cardiac cine MRI

Rosa-María Menchón-Lara, Federico Simmross-Wattenberg, Pablo Casaseca-de-la-Higuera, Marcos Martín-Fernández, Carlos Alberola-López
2019 Insights into Imaging  
Additionally, clinical relevance, main challenges, and future trends of this image modality are outlined.  ...  Thus, this paper aims to provide a general vision about cine MRI as the standard procedure in functional evaluation of the heart, focusing on technical methodologies.  ...  In [97] , Jeong et al. perform a validation study of 3D cine MRI of the heart in a single BH using kat-ARC, which is an auto-calibrating PI method for Cartesian sampling.  ... 
doi:10.1186/s13244-019-0754-2 pmid:31549235 pmcid:PMC6757088 fatcat:s5574wj5pjadhbq5rah7k3h6lu

What links ventilator driving pressure with survival in the acute respiratory distress syndrome? A computational study

Anup Das, Luigi Camporota, Jonathan G. Hardman, Declan G. Bates
2019 Respiratory Research  
Each of these in silico patients was subjected to the same range of values of driving pressure and positive end expiratory pressure (PEEP) used in the previous analyses of clinical trial data.  ...  These findings await full validation in prospective clinical trials.  ...  [23] , using a genetic-algorithm based optimization strategy, as previously described in [17] .  ... 
doi:10.1186/s12931-019-0990-5 pmid:30744629 pmcid:PMC6371576 fatcat:ebiqyvfbdzcc7az7irw7txlbqu
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