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ABNORMALITIES OF CORTICAL NEURAL SYNCHRONIZATION MECHANISMS IN SUBJECTS WITH MILD COGNITIVE IMPAIRMENT DUE TO ALZHEIMER'S AND PARKINSON'S DISEASES: AN EEG STUDY

Roberta Lizio, Claudio Del Percio, Susanna Cordone, Susanna Lopez, Andrea Soricelli, Raffaele Ferri, Flavio Nobili, Francesco Famà, Dag Aarsland, Francesco Orzi, Carla Buttinelli, Franco Giubilei (+16 others)
2017 Alzheimer's & Dementia  
synchronization in groups of patients with mild cognitive impairment due to Alzheimer's disease (ADMCI) and Parkinson's disease (PDMCI) as compared to healthy subjects.  ...  The aim of this retrospective and exploratory study was that the cortical sources of resting state eyes-closed electroencephalographic (rsEEG) rhythms might reveal different abnormalities in cortical neural  ...  with mild cognitive impairment due to Alzheimer's disease (ADMCI) and Parkinson's disease (PDMCI) and education.  ... 
doi:10.1016/j.jalz.2017.06.1411 fatcat:ljijnyhblrhkznkiuk7ljo5vae

Classification of Healthy Subjects and Alzheimer's Disease Patients with Dementia from Cortical Sources of Resting State EEG Rhythms: A Study Using Artificial Neural Networks

Antonio I. Triggiani, Vitoantonio Bevilacqua, Antonio Brunetti, Roberta Lizio, Giacomo Tattoli, Fabio Cassano, Andrea Soricelli, Raffaele Ferri, Flavio Nobili, Loreto Gesualdo, Maria R. Barulli, Rosanna Tortelli (+15 others)
2017 Frontiers in Neuroscience  
Previous evidence showed a 75.5% best accuracy in the classification of 120 Alzheimer's disease (AD) patients with dementia and 100 matched normal elderly (Nold) subjects based on cortical source current  ...  density and linear lagged connectivity estimated by eLORETA freeware from resting state eyes-closed electroencephalographic (rsEEG) rhythms (Babiloni et al., 2016a) .  ...  ACKNOWLEDGMENTS The present study was developed and granted in the framework of the following projects: "Smart Health 2.  ... 
doi:10.3389/fnins.2016.00604 pmid:28184183 pmcid:PMC5266711 fatcat:prcztuptvnf6hppn5z3qq5mhzq

Functional cortical source connectivity of resting state electroencephalographic alpha rhythms shows similar abnormalities in patients with mild cognitive impairment due to Alzheimer's and Parkinson's diseases

Claudio Babiloni, Claudio Del Percio, Roberta Lizio, Giuseppe Noce, Susanna Lopez, Andrea Soricelli, Raffaele Ferri, Maria Teresa Pascarelli, Valentina Catania, Flavio Nobili, Dario Arnaldi, Francesco Famà (+26 others)
2018 Clinical Neurophysiology  
Functional cortical source connectivity of resting state electroencephalographic alpha rhythms shows similar abnormalities in patients with mild cognitive impairment due to Alzheimer's and Parkinson's  ...  diseases.  ...  Acknowledgements The present study was developed based on the data of the informal European Consortium PDWAVES and European Consortium of Dementia with Lewy Body.  ... 
doi:10.1016/j.clinph.2018.01.009 pmid:29448151 fatcat:klmcvdapurbaboesn6wvoarule

Abnormalities of Cortical Sources of Resting State Delta Electroencephalographic Rhythms Are Related to Epileptiform Activity in Patients With Amnesic Mild Cognitive Impairment Not Due to Alzheimer's Disease

Claudio Babiloni, Giuseppe Noce, Carlo Di Bonaventura, Roberta Lizio, Maria Teresa Pascarelli, Federico Tucci, Andrea Soricelli, Raffaele Ferri, Flavio Nobili, Francesco Famà, Eleonora Palma, Pierangelo Cifelli (+4 others)
2020 Frontiers in Neurology  
In the present exploratory and retrospective study, we hypothesized that cortical sources of resting state eyes-closed electroencephalographic (rsEEG) rhythms might be more abnormal in patients with epileptiform  ...  Individual alpha frequency peak (IAF) was used to determine the delta, theta, and alpha frequency bands of rsEEG rhythms. Fixed beta and gamma bands were also considered.  ...  The present study was developed based on the data of the European-Asiatic Consortium PDWAVES and European Consortia of Dementia with Lewy Body and FP7-IMI PharmaCog (www.pharmacog.org) projects.  ... 
doi:10.3389/fneur.2020.514136 pmid:33192962 pmcid:PMC7644902 fatcat:jyoneyonxrevpghciaprcxyk4q

ABNORMALITIES OF RESTING STATE FUNCTIONAL CORTICAL CONNECTIVITY IN PATIENTS WITH DEMENTIA DUE TO ALZHEIMER'S AND LEWY BODY DISEASES: AN EEG STUDY

Claudio Babiloni, Claudio Del Percio, Roberta Lizio, Giuseppe Noce, Susanna Lopez, Andrea Soricelli, Raffaele Ferri, Flavio Mariano Nobili, Dario Arnaldi, Francesco Famà, Dag Aarsland, Francesco Orzi (+21 others)
2018 Alzheimer's & Dementia  
Previous evidence showed abnormal posterior sources of resting state delta (<4Hz) and alpha (8-12 Hz) rhythms in patients with Alzheimer's disease with dementia (ADD), Parkinson's disease with dementia  ...  Resting state eyes-closed electroencephalographic (rsEEG) rhythms had been collected in 42 ADD, 42 PDD, 34 DLB, and 40 normal healthy elderly (Nold) subjects. eLORETA freeware estimated the functional  ...  The members and institutional affiliations of the Consortium are reported in the cover page of this manuscript.  ... 
doi:10.1016/j.jalz.2018.06.2387 fatcat:kuw5jvorqrfznh26npdx2juhhq

Abnormalities of resting-state EEG in patients with prodromal and overt dementia with Lewy bodies: Relation to clinical symptoms

Maria Teresa Pascarelli, Claudio Del Percio, Maria Francesca De Pandis, Raffaele Ferri, Roberta Lizio, Giuseppe Noce, Susanna Lopez, Marco Rizzo, Andrea Soricelli, Flavio Nobili, Dario Arnaldi, Francesco Famà (+29 others)
2020 Clinical Neurophysiology  
Here we tested if cortical sources of resting state electroencephalographic (rsEEG) rhythms may differ in sub-groups of patients with prodromal and overt dementia with Lewy bodies (DLB) as a function of  ...  We extracted clinical, demographic and rsEEG datasets in matched DLB patients (N = 60) and control Alzheimer's disease (AD, N = 60) and healthy elderly (Nold, N = 60) seniors from our international database  ...  Acknowledgements The present study was developed based on the data of the informal European Consortium PDWAVES and European Consortium of Dementia with Lewy Bodies.  ... 
doi:10.1016/j.clinph.2020.09.004 pmid:33039748 fatcat:otyoyvnhijhsdkmuixkri35564

What Electrophysiology Tells Us About Alzheimer's Disease: A Window into the Synchronization and Connectivity of Brain Neurons

Claudio Babiloni, Katarzyna Blinowska, Laura Bonanni, Andrej Cichocki, Willem De Haan, Claudio del Percio, Bruno Dubois, Javier Escudero, Alberto Fernández, Giovanni Frisoni, Bahar Guntekin, Mihaly Hajos (+29 others)
2019 Neurobiology of Aging  
However, current international guidelines do not endorse the use of electroencephalographic (EEG)/magnetoencephalographic (MEG) biomarkers in clinical trials performed in patients with Alzheimer's disease  ...  Converging evidence shows relationships between abnormalities in EEG/MEG markers and cognitive deficits in groups of AD patients at different disease stages.  ...  Furthermore, a combination of linear and nonlinear measures of interdependence of rsEEG rhythms reached a classification accuracy of 80-85% in the discrimination of Nold and MCI individuals (Dauwels et  ... 
doi:10.1016/j.neurobiolaging.2019.09.008 pmid:31739167 fatcat:4qovqzkklfduvane3tuttfnfem

Revolution of Alzheimer Precision Neurology. Passageway of Systems Biology and Neurophysiology

Harald Hampel, Nicola Toschi, Claudio Babiloni, Filippo Baldacci, Keith L. Black, Arun L.W. Bokde, René S. Bun, Francesco Cacciola, Enrica Cavedo, Patrizia A. Chiesa, Olivier Colliot, Cristina-Maria Coman (+32 others)
2018 Journal of Alzheimer's Disease  
different diseases and subgroups at different stages of pathophysiological progression.  ...  neurodegenerative disease (ND) populations, within the wide continuous biological and clinical spectrum of ND, applying high-throughput and Hampel et al.  ...  of AD patients), specificity (detection of healthy subjects or patients with other diseases), and global classification accuracy.  ... 
doi:10.3233/jad-179932 pmid:29562524 pmcid:PMC6008221 fatcat:j3u6gkzfqbg47kv4o2hpkjadn4

A Review of EEG Signal Analysis for Diagnosis of Neurological Disorders using Machine Learning

Vandana Joshi, Nirali Nanavati
2021 Journal of Biomedical Photonics & Engineering  
These disorders include epilepsy, Alzheimer's disease, dementia, cerebrovascular diseases including stroke, migraine, Parkinson's disease and numerous other disorders.  ...  Neurological disorders are diseases that affect the brain and the central autonomic nervous systems. These disorders take a huge toll on an individual's health and general well-being.  ...  Disclosures All authors declare that there is no conflict of interests in this paper.  ... 
doi:10.18287/10.18287/jbpe21.07.040201 fatcat:kmehkwolyvcgjamcz4xcn3k45y

Index [chapter]

2020 Diagnosis and Management in Dementia  
See Resting state eyes-closed electroencephalographic rhythms (rsEEG rhythms) rTMS. See Repetitive transcranial magnetic stimulation (rTMS) RUDAS.  ...  See Regions of interest (ROIs) ROS. See Reactive oxygen species (ROS) Rowland Universal Dementia Assessment Scale (RUDAS), 380 rsEEG rhythms.  ... 
doi:10.1016/b978-0-12-815854-8.20001-3 fatcat:7mlndjaemjae3nsbgjfczcnrcu

19th biennial IPEG Meeting

Igor Timofeev, Leon Kenemans, P. F. Fabene, A. Ahnaou, Sebastian Olbrich, Robert Oostenveld, Martijn Arns, Nash Boutros, Fernando Lopes da Silva, Igor Timofeev, Ole Jensen, Sandra K. Loo (+404 others)
2016 Neuropsychiatric Electrophysiology  
research program SGS (SGS15/229/OHK4/3 T/17), MH CZ -DRO ("National Institute of Mental Health -NIMH) project nr.: 00023752 and PRVOUK34.  ...  I declare no conflict of interests.  ...  instrumental assessment of patients with Alzheimer's disease (AD).  ... 
doi:10.1186/s40810-016-0021-4 fatcat:iynffofbojdx3nspgskpizfwt4

Robust EEG-Based Biomarkers to Detect Alzheimer's Disease

Ali H. Al-Nuaimi, Marina Blūma, Shaymaa S. Al-Juboori, Chima S. Eke, Emmanuel Jammeh, Lingfen Sun, Emmanuel Ifeachor
2021 Brain Sciences  
Biomarkers to detect Alzheimer's disease (AD) would enable patients to gain access to appropriate services and may facilitate the development of new therapies.  ...  A large number of existing and novel EEG biomarkers associated with slowing of EEG, reduction in EEG complexity. and decrease in EEG connectivity were investigated.  ...  Curie ITN-ETN project with the short title "BBDiag" (http://bbdiag-itn-etn.eu) is grate-fully acknowledged. Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/brainsci11081026 fatcat:xqjzdadktnfkfbkb5atj562ody

ACNP 58th Annual Meeting: Poster Session III

2019 Neuropsychopharmacology  
Methods: A total of 23 individuals with PTSD (13M, 10F) and 26 trauma-exposed and non-exposed otherwise healthy individuals (18M, 8F) were imaged.  ...  Cognitive dysfunction in Alzheimer's disease (AD) is usually accompanied by various behavioral and psychological symptoms of dementia (BPSD) and dysfunctions in daily activities.  ...  , and Parkinson's disease.  ... 
doi:10.1038/s41386-019-0547-9 pmid:31801974 pmcid:PMC6957926 fatcat:dd7d43ysfvc5bbbstfl73szya4

Proceedings of the 3rd International Mobile Brain/Body Imaging Conference

(:Unkn) Unknown, Technische Universität Berlin, Technische Universität Berlin, Klaus Gramann
2018
investigate brain activity while participants actively move in and interact with their environment.  ...  This imaging approach will lead to new insights into the brain functions underlying active behavior and the impact of behavior on brain dynamics and vice versa, it can be used for the development of more  ...  the neural underpinnings of mobility in aging.  ... 
doi:10.14279/depositonce-7236 fatcat:cvldfxw4yvgh5dis4vkzi2aqfy