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Conformance Control for Tight Oil Cyclic Gas Injection Using Foam

Falin Wei, Song Zhang, Yilin Xi, Zhouyuan Zhu, Chunming Xiong, Chuanzhen Zang, Junjian Li, Kouqi Liu
2022 Geofluids  
Cyclic gas injection has been proven to be an effective enhanced oil recovery (EOR) technique for tight oil reservoirs. During such processes, we expect recovery mechanisms such as oil swelling, oil viscosity reduction, vaporization, and pressure support, which highly relies on the successful conformance control of the injected gas. In this work, we present the numerical simulation study of using foam for improving the conformance control of cyclic gas injection in tight oil reservoir. We focus
more » ... on improving two categories of conformance control problems using foam, making the injection profile for single well more evenly distributed and mitigating the gas breakthrough to adjacent wells through the connected hydraulic fractures in a multiwell setting. The simulation results show that foam has shown major impact in improving the gas conformance control in both cases. Typical recovery factor improvements are estimated to be up to 1% for lean gas injection in this tight oil reservoir. In conclusion, we have demonstrated the great potential of using foam to improve the conformance in tight oil cyclic gas injection process.
doi:10.1155/2022/6571525 fatcat:3pja36cws5fixa3ct3gryonh5y

Architecture, implementation and application of complex event processing in enterprise information systems based on RFID

Chuanzhen Zang, Yushun Fan, Renjing Liu
2008 Information Systems Frontiers  
Chuanzhen Yushun Renjing  ...  Zang received the Ph.D. degree in Control Theory and Engineering from the Department of Automation, Tsinghua University.  ... 
doi:10.1007/s10796-008-9109-0 fatcat:p7mj37hob5hzhdyjztdxshvpse

A20/TNFAIP3 Regulates the DNA Damage Response and Mediates Tumor Cell Resistance to DNA-Damaging Therapy

Chuanzhen Yang, Weicheng Zang, Zefang Tang, Yapeng Ji, Ruidan Xu, Yongfeng Yang, Aiping Luo, Bin Hu, Zemin Zhang, Zhihua Liu, Xiaofeng Zheng
2017 Cancer Research  
A competent DNA damage response (DDR) helps prevent cancer, but once cancer has arisen, DDR can blunt the efficacy of chemotherapy and radiotherapy that cause lethal DNA breakage in cancer cells. Thus, blocking DDR may improve the efficacy of these modalities. Here, we report a new DDR mechanism that interfaces with inflammatory signaling and might be blocked to improve anticancer outcomes. Specifically, we report that the ubiquitin-editing enzyme A20/TNFAIP3 binds and inhibits the E3 ubiquitin
more » ... ligase RNF168, which is responsible for regulating histone H2A turnover critical for proper DNA repair. A20 induced after DNA damage disrupted RNF168-H2A interaction in a manner independent of its enzymatic activity. Furthermore, it inhibited accumulation of RNF168 and downstream repair protein 53BP1 during DNA repair. A20 was also required for disassembly of RNF168 and 53BP1 from damage sites after repair. Conversely, A20 deletion increased the efficiency of error-prone nonhomologous DNA end-joining and decreased errorfree DNA homologous recombination, destablizing the genome and increasing sensitivity to DNA damage. In clinical specimens of invasive breast carcinoma, A20 was widely overexpressed, consistent with its candidacy as a therapeutic target. Taken together, our findings suggest that A20 is critical for proper functioning of the DDR in cancer cells and it establishes a new link between this NFkBregulated ubiquitin-editing enzyme and the DDR pathway. Significance: This study identifies the ubiquitin-editing enzyme A20 as a key factor in mediating cancer cell resistance to DNAdamaging therapy, with implications for blocking its function to leverage the efficacy of chemotherapy and radiotherapy. Cancer Res; 78(4); 1069-82. Ó2017 AACR.
doi:10.1158/0008-5472.can-17-2143 pmid:29233925 fatcat:wp5newjunffwdoubeudlw3plqa

Critical regulation of CD4+ T cell survival and autoimmunity by β-arrestin 1

Yufeng Shi, Yan Feng, Jiuhong Kang, Chang Liu, Zhenxin Li, Dangsheng Li, Wei Cao, Ju Qiu, Zhengliang Guo, Enguang Bi, Lei Zang, Chuanzhen Lu (+2 others)
2007 Nature Immunology  
doi:10.1038/ni1489 pmid:17618287 fatcat:emdwkdjkynhjnj3nw4hsnzy3hm

Cellular redox sensor HSCARG negatively regulates the translesion synthesis pathway and exacerbates mammary tumorigenesis

Weicheng Zang, Chuanzhen Yang, Tingting Li, Liming Liao, Xiaofeng Zheng
2019 Proceedings of the National Academy of Sciences of the United States of America  
| Zang et al. | Zang et al. | Zang et al.  ...  | Zang et al.  ... 
doi:10.1073/pnas.1910250116 pmid:31796584 pmcid:PMC6926050 fatcat:aosmgkew75hcxm4d47aousjm54

Ribosomal protein L6 (RPL6) is recruited to DNA damage sites in a poly(ADP-ribose) polymerase–dependent manner and regulates the DNA damage response

Chuanzhen Yang, Weicheng Zang, Yapeng Ji, Tingting Li, Yongfeng Yang, Xiaofeng Zheng
2018 Journal of Biological Chemistry  
Ribosomal proteins are the building blocks of ribosome biogenesis. Beyond their known participation in ribosome assembly, the ribosome-independent functions of ribosomal proteins are largely unknown. Here, using immunoprecipitation, subcellular fractionation, His-ubiquitin pulldown, and immunofluorescence microscopy assays, along with siRNA-based knockdown approaches, we demonstrate that ribosomal protein L6 (RPL6) directly interacts with histone H2A and is involved in the DNA damage response
more » ... DR). We found that in response to DNA damage, RPL6 is recruited to DNA damage sites in a poly(ADP-ribose) polymerase (PARP)-dependent manner, promoting its interaction with H2A. We also observed that RPL6 depletion attenuates the interaction between mediator of DNA damage checkpoint 1 (MDC1) and H2A histone family member X, phosphorylated (γH2AX), impairs the accumulation of MDC1 at DNA damage sites, and reduces both the recruitment of ring finger protein 168 (RNF168) and H2A Lys-15 ubiquitination (H2AK15ub). These RPL6 depletion-induced events subsequently inhibited the recruitment of the following downstream repair proteins: tumor protein P53-binding protein 1 (TP53BP1) and BRCA1, DNA repair-associated (BRCA1). Moreover, the RPL6 knockdown resulted in defects in the DNA damage-induced G2-M checkpoint, DNA damage repair, and cell survival. In conclusion, our study identifies RPL6 as a critical regulatory factor involved in the DDR. These findings expand our knowledge of the extraribosomal functions of ribosomal proteins in cell physiology and deepen our understanding of the molecular mechanisms underlying DDR regulation.
doi:10.1074/jbc.ra118.007009 pmid:30598506 pmcid:PMC6393625 fatcat:arg4xwf23vcopf6jrllw4xu36q

Cooperative mixed strategy for service selection in service oriented architecture

Yimin Shen, Yushun Fan
2007 2007 IEEE International Conference on Systems, Man and Cybernetics  
ACKNOWLEDGMENT Yimin Shen would like to thank Sen Zeng, Wei Tan, John He, Jian Zhou, Suiping Jiang, Xiaoyan Bin, and Chuanzhen Zang for their comments which led to improvements of this paper.  ... 
doi:10.1109/icsmc.2007.4413993 dblp:conf/smc/ShenF07 fatcat:ntlzfqovofe7lhz6z5y6ckha2q

Research of Fracture Mechanics Applied in the Cutting Process of Plastic Metals

Hongyan Shi, Xianfeng Zhao, Ziqin Wang, Xueting Jiang, Zichuan Zou, Xiaolong Hu
2019 Xibei Gongye Daxue Xuebao/Journal of Northwestern Polytechnical University  
Jour• nal of Manufacture Science and Engineering, 2015, 137(6) : 061002 [ 59] JIAN Zang, JUN Zhao, ANHAI Li, et al.  ...  International Journal Advanced Manufacturing Technology, 2018, 98: 119•127 [60] SU Rui, HUANG Chuanzhen, XU Longhua.  ... 
doi:10.1051/jnwpu/20193761209 fatcat:qovv7rd6yveenipvu5fcthulea

European Benchmarks for the Chinese Language (EBCL) [article]

(:Unkn) Unknown, Universitätsbibliothek Der FU Berlin, Universitätsbibliothek Der FU Berlin, Andreas Guder
chéngjì 城市 chéngshì 橙色 chéngsè 橙汁 chéngzhī 吃 chī 吃饭 chīfàn 迟到 chídào 出 chū 出发 chūfā 出国 chūguó 出口 chūkǒu 出来 chūlái 出去 chūqù 出生 chūshēng 出租(汽)车 chūzū (qì)chē 初中 chūzhōng 除了 chúle 厨房 chúfáng 穿 chuān 传真 chuánzhēn  ...  ) hēi (sè) 红(色) hóng (sè) 蓝(色) lán (sè) 绿(色) lǜ (sè) 橙色 chéngsè 粉红色 fěnhóngsè 灰色 huīsè 紫色 zǐsè 棕色 zōngsè 5.2.6 Material / Material 木头 mùtou 石头 shítou 丝/丝绸 sī/sīchóu 5.2.7 Others / Andere 干净 gānjìng 脏 zàng  ... 
doi:10.17169/refubium-19534 fatcat:yibb2hsbxnf35dgeyriul2zelu