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Chronos

Rishi Kapoor, George Porter, Malveeka Tewari, Geoffrey M. Voelker, Amin Vahdat
2012 Proceedings of the Third ACM Symposium on Cloud Computing - SoCC '12  
We propose Chronos, a framework to deliver predictable, low latency in data center applications.  ...  In data center applications, predictability in service time and controlled latency, especially tail latency, are essential for building performant applications.  ...  To address these challenges, we propose Chronos, a communication framework that leverages both kernel bypass and NIC-level request dispatch to deliver predictable low latency for data center applications  ... 
doi:10.1145/2391229.2391238 dblp:conf/cloud/KapoorPTVV12 fatcat:5p6aqwgqwfbrtdwtjjclhl5l6i

Ultrafast optogenetic stimulation of the auditory pathway by targeting‐optimized Chronos

Daniel Keppeler, Ricardo Martins Merino, David Lopez de la Morena, Burak Bali, Antoine Tarquin Huet, Anna Gehrt, Christian Wrobel, Swati Subramanian, Tobias Dombrowski, Fred Wolf, Vladan Rankovic, Andreas Neef (+1 others)
2018 EMBO Journal  
Optogenetic tools, providing non-invasive control over selected cells, have the potential to revolutionize sensory prostheses for humans.  ...  In order to enhance neural expression, we improved its trafficking to the plasma membrane (Chronos-ES/TS).  ...  Edward Boyden for providing the Chronos-EGFP construct and Rachel Care for contributing in the initial phase of the project.  ... 
doi:10.15252/embj.201899649 pmid:30396994 pmcid:PMC6293277 fatcat:5p5z3bkbnzfr3ibxwk4xh2aygi

High-fidelity optical excitation of cortico-cortical projections at physiological frequencies

Charles A. Hass, Lindsey L. Glickfeld
2016 Journal of Neurophysiology  
However, because of the difficulty of measuring activity in axons, our knowledge of the reliability of optogenetic axonal stimulation has relied on data from somatic recordings.  ...  Repetitive stimulation of axons with ChR2 resulted in a 70% reduction in the fiber volley amplitude and a 60% increase in the latency at all frequencies tested (10 -40 Hz).  ...  ACKNOWLEDGMENTS We thank Emily Burke, Amy Kristl, Courtney Dobrott, and Kyra Leonard for technical assistance with viral injections and post hoc histology; Greg Horwitz and Yasmine El-Shamayleh for the  ... 
doi:10.1152/jn.00456.2016 pmid:27489370 pmcid:PMC5102304 fatcat:4nspqpwf6jfkjiq3qdhbpkhnxe

5GWF 2018 Subject Index

2018 2018 IEEE 5G World Forum (5GWF)  
To IoT Applications On the Ultra-Dense Small Cell Deployment for 5G Networks Optimal Frequency Hopping Patterns for FH-SCMA Optimizing Over-The-Air Virtual Reality Broadcast Transmissions with Low-Latency  ...  Evaluating Power Density for 5G Applications Learning-Based Resource Allocation for Data-Intensive and Immersive Tactile ApplicationsLinear GFDM: A Low Out-of-band Emission Configuration for 5G Air  ... 
doi:10.1109/5gwf.2018.8516982 fatcat:inelckftp5euxcsjrhezfl5u5y

WCET Analysis of the mC/OS-II Real-Time Kernel

Mingsong Lv, Nan Guan, Yi Zhang, Rui Chen, Qingxu Deng, Ge Yu, Wang Yi
2009 2009 International Conference on Computational Science and Engineering  
Traditionally, WCET analysis mainly deals with application programs, while it is crucial to know whether the RTOS also behaves in a timely predictable manner.  ...  In complex systems with real-time operating systems (RTOS), the timing properties of the system are decided by both the applications and the RTOS.  ...  Simply applying static analysis techniques designed for applications may yield low-quality or even incorrect results.  ... 
doi:10.1109/cse.2009.82 dblp:conf/cse/LvGZCDYY09 fatcat:pfixmuts35hrdfdcdqhuv2dwq4

The HLA-B14 peptide binding site can accommodate peptides with different combinations of anchor residues

M DiBrino, K C Parker, D H Margulies, J Shiloach, R V Turner, W E Biddison, J E Coligan
1994 Journal of Biological Chemistry  
By using binding data to calculate the contribution to binding of each amino acid at anchor positions and predicting the stability of all possible nonapeptide complexes that could be formed from antigenic  ...  Combinations of any three of these amino acids sufficed for binding to HLA-B14 in vitro.  ...  ACKNOWLEDGEMENTS We thank Marta Gajowa and Fabio Simony-Conesa for performing part of mice viral injections; Cecile Jouffret for help in cell culture maintenance; Oscar Hernandez for contributing simulation  ... 
pmid:7528217 fatcat:psigsokvfraa5exampkgc7zlva

RIoTBench: An IoT benchmark for distributed stream processing systems

Anshu Shukla, Shilpa Chaturvedi, Yogesh Simmhan
2017 Concurrency and Computation  
The applications are based on common IoT patterns for data pre-processing, statistical summarization and predictive analytics.  ...  The inherent closedloop responsiveness and decision making of IoT applications make them ideal candidates for using low latency and scalable stream processing platforms.  ...  The experiments on Microsoft Azure were supported through a grant from Azure for Research.  ... 
doi:10.1002/cpe.4257 fatcat:rivgwd7jqbdr5gu7lc6rkshzne

Optogenetic activation of the inhibitory nigro-collicular circuit evokes orienting movements in mice [article]

Claudio A Villalobos, Michele A Basso
2020 bioRxiv   pre-print
The latency of orienting movements relative to the stimulation in vivo was similar to the latency of rebound spiking in vitro.  ...  In contrast to predictions from the current model of basal ganglia (BG) function, we report here that increasing inhibition from the BG to the superior colliculus (SC) through the substantia nigra (nigra  ...  The circles represent the two nigrae, the two SCs and the two BS centers and the images 624 below show predicted outcomes of optogenetic activation of the nigro-collicular circuit.  ... 
doi:10.1101/2020.05.21.107680 fatcat:yat5gtop6vei7gumxuoudr7wai

Static worst-case execution time analysis of the μC/OS-II real-time kernel

Mingsong Lv, Nan Guan, Qingxu Deng, Ge Yu, Yi Wang
2010 Frontiers of Computer Science in China  
Traditionally, WCET analysis mainly deals with application programs, while it is crucial to know whether RTOS also behaves in a timely predictable manner.  ...  In complex systems with real-time operating systems (RTOS), the timing properties of the system are decided by both the applications and RTOS.  ...  Simply applying static analysis techniques designed for applications may yield low-quality or even incorrect results. In an RTOS, certain parts of the system code are particularly time-critical.  ... 
doi:10.1007/s11704-009-0073-8 fatcat:4kzvphjpdbdvfaefhbefifgo3u

Tales of the Tail

Jialin Li, Naveen Kr. Sharma, Dan R. K. Ports, Steven D. Gribble
2014 Proceedings of the ACM Symposium on Cloud Computing - SOCC '14  
models alone predict.  ...  To deliver fast responses, the median and tail latencies of a service's components must be low.  ...  Acknowledgements We thank the anonymous reviewers and our shepherd Ymir Vigfusson for their feedback.  ... 
doi:10.1145/2670979.2670988 dblp:conf/cloud/LiSPG14 fatcat:56cac52pqjebbbbqhmrnr3dbrm

Understanding Skin Chronobiology to Unveil and Transform Dermal Chronotherapeutics: Paving the Way for the Future

Jagruti Thoke, Shivangi Patel, Anuradha Majumdar
2021 Chronobiology in Medicine  
The recent application of chronopharmacological studies in age prediction, wound healing, and fat metabolism is summarized.  ...  Chrono pharmacology elaborates on how the outcomes of drug changes with biological timing and endogenous rhythm.  ...  Table 3 . 3 Studies on chrono therapeutics Class Dosage form Drug Clinical application Chrono therapeutics Reference Vitamin Cream Maxacalcitol Used in skin inflammation (psoriasis) Drug effective  ... 
doi:10.33069/cim.2020.0032 fatcat:y2g7urt2jbgptengsceqa7zane

Experience-dependent plasticity in an innate social behavior is mediated by hypothalamic LTP [article]

Stefanos Stagkourakis, Giada Spigolon, Grace Liu, David J. Anderson
2020 biorxiv/medrxiv   pre-print
Together, these findings reveal that LTP at a hypothalamic circuit node mediates a form of experience-dependent plasticity in an innate social behavior, and a potential hormone-dependent basis for individual  ...  demonstrate further that the optogenetic induction of such LTP in vivo facilitates, while optogenetic long-term depression (LTD) diminishes, the behavioral effect of aggression training, implying a causal role for  ...  (C) Overlay of reconstruction data generated in Imaris against 3D rendering for the dendritic segment presented in B.  ... 
doi:10.1101/2020.07.21.214619 fatcat:qpwuclmb6bb5nga456ui74mnia

Experience-dependent plasticity in an innate social behavior is mediated by hypothalamic LTP

Stefanos Stagkourakis, Giada Spigolon, Grace Liu, David J. Anderson
2020 Proceedings of the National Academy of Sciences of the United States of America  
Together, these findings reveal that LTP at a hypothalamic circuit node mediates a form of experience-dependent plasticity in an innate social behavior, and a potential hormone-dependent basis for individual  ...  demonstrate further that the optogenetic induction of such LTP in vivo facilitates, while optogenetic long-term depression (LTD) diminishes, the behavioral effect of aggression training, implying a causal role for  ...  (C) Overlay of reconstruction data generated in Imaris against 3D rendering for the dendritic segment presented in B.  ... 
doi:10.1073/pnas.2011782117 pmid:32973099 fatcat:tshpib62abdtpihthltfdwnjqy

Theoretical Analysis for Scale-down-Aware Service Allocation in Cloud Storage Systems

Angli Liu
2013 International Journal of Electrical and Computer Engineering (IJECE)  
placement in data centers.  ...  In this paper we propose an algorithm in which to maximize the number of freed-up machines in data centers, machines that host purely scale-down instances, which are reuiqred to be shut down for energy  ...  Chronos [25] changes the current status of setting low utilization to rein in latency outliers.  ... 
doi:10.11591/ijece.v3i1.1792 fatcat:qllic7icybdtpmdxmfi4narmxa

The Proceedings of First Work-in-Progress Session of The CSI International Symposium on Real-Time and Embedded Systems and Technologies [article]

Ali Behnoudfar, Seyyed Hossein Hosseini Zahani, Mojtaba Hatami, Mahmoud Naghibzadeh, Boshra Taheri, Fathieh Faghih, Mehdi Kargahi
2019 arXiv   pre-print
The program committee of RTEST 2018 consists of 54 top researchers in the mentioned fields from top universities, industries, and research centers around the world.  ...  Each submission has been reviewed by 3 to 5 independent referees, for its quality, originality, contribution, clarity of presentation, and relevance to the symposium topics.  ...  Energy hotspots for the sensor, based on what is presented in this article, are equivalent to the low productivity of the data reported by the sensor.  ... 
arXiv:1904.06995v1 fatcat:7lvriwiw5fd55njqithwclrxru
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