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White matter mapping is needed
<span title="">2004</span>
<i title="Elsevier BV">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/h77v7bacwjdqjifp5ymnikreee" style="color: black;">Neurobiology of Aging</a>
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Bilingualism affects picture naming but not picture classification
<span title="">2005</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ajltsigzdbc6zo6q2oqboml2gi" style="color: black;">Memory & Cognition</a>
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Bilinguals named pictures in their dominant language more slowly (and with more errors) than did monolinguals. In contrast, bilinguals named the same pictures as quickly as did monolinguals on the fifth presentation (in Experiment 2) and classified them (as human made or natural) as quickly and accurately as did monolinguals (in Experiment 1). In addition, bilinguals retrieved English picture names more quickly if they knew the name in both Spanish and English (on the basis of a translation
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... that bilinguals completed after the timed tasks), and monolingual response times for the same materials suggested that this finding was not obtained simply because names that were easier to translate were easier in general. These findings suggest that bilinguals differ from monolinguals at a postconceptual processing level, that implicit activation of lexical representations in the nontarget language can facilitate retrieval in the target language, and that being bilingual is analogous to having a lexicon full of lower frequency words, relative to monolinguals.
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Regional shape abnormalities in mild cognitive impairment and Alzheimer's disease
<span title="">2009</span>
<i title="Elsevier BV">
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., 2000; Fennema-Notestine et al., in press ). ...
., 2001; Fennema-Notestine et al., in press) and ventricular enlargement in both MCI and AD (Chetelat and Baron, 2003; Ridha et al., 2008; Fennema-Notestine et al., in press ). ...
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Cumulative trauma, adversity and grief symptoms associated with fronto-temporal regions in life-course persistent delinquent boys
<span title="">2016</span>
<i title="Elsevier BV">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/pqgqyradj5fpvb5x22wo3ecaui" style="color: black;">Psychiatry Research : Neuroimaging</a>
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Early childhood adversity is associated with cognitive, psychiatric and neurologic sequelae that persist into adulthood (Fennema-Notestine et al., 2002; Hart and Rubia, 2012; McCrory et al., 2010; Sheriday ...
First, a multivariate tissue segmentation technique that employs the T1, T2, and PD (based on Jernigan et al., 2011; Fennema-Notestine et al, 2013 ) measured global gray and white matter volumes; abnormal ...
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More ?mapping? in brain mapping: Statistical comparison of effects
<span title="2003-05-21">2003</span>
<i title="Wiley">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/wtsn7qcbmrhjppax2iuhu4xj2m" style="color: black;">Human Brain Mapping</a>
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The term "mapping" in the context of brain imaging conveys to most the concept of localization; that is, a brain map is meant to reveal a relationship between some condition or parameter and specific sites within the brain. However, in reality, conventional voxel-based maps of brain function, or for that matter of brain structure, are generally constructed using analyses that yield no basis for inferences regarding the spatial nonuniformity of the effects. In the normal analysis path for
<span class="external-identifiers">
<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1002/hbm.10108">doi:10.1002/hbm.10108</a>
<a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/12768533">pmid:12768533</a>
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... nal images, for example, there is nowhere a statistical comparison of the observed effect in any voxel relative to that in any other voxel. Under these circumstances, strictly speaking, the presence of significant activation serves as a legitimate basis only for inferences about the brain as a unit. In their discussion of results, investigators rarely are content to confirm the brain's role, and instead generally prefer to interpret the spatial patterns they have observed. Since "pattern" implies nonuniform effects over the map, this is equivalent to interpreting results without bothering to test their significance, a practice most of the experimentally-trained would eschew in other contexts. In this review, we appeal to investigators to adopt a new standard of data presentation that facilitates comparison of effects across the map. Evidence for sufficient effect size difference between the effects in structures of interest should be a prerequisite to the interpretation of spatial patterns of activation. Hum. Brain Mapping 19:90 -95, 2003.
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The Cerebral Blood Flow Biomedical Informatics Research Network (CBFBIRN) data repository
<span title="">2016</span>
<i title="Elsevier BV">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a>
</i>
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Arterial spin labeling (ASL) MRI provides an accurate and reliable measure of cerebral blood flow (CBF). A rapidly growing number of CBF measures are being collected both in clinical and research settings around the world, resulting in a large volume of data across a wide spectrum of study populations and health conditions. Here, we describe a central CBF data repository with integrated processing workflows, referred to as the Cerebral Blood Flow Biomedical Informatics Research Network
<span class="external-identifiers">
<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2015.05.059">doi:10.1016/j.neuroimage.2015.05.059</a>
<a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/26032887">pmid:26032887</a>
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... . The CBFBIRN provides an integrated framework for the analysis and comparison of CBF measures across studies and sites. In this work, we introduce the main capabilities of the CBFBIRN (data storage, processing and sharing), describe what types of data are available, explain how users can contribute to the data repository and access existing data from it, and discuss our long term plans for the CBFBIRN.
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Changes in cognitive function in women with HIV infection and early life stress
<span title="2016-07-11">2016</span>
<i title="Informa UK Limited">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ktoyac6yu5exzklskadyxor4ai" style="color: black;">AIDS Care</a>
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., 2013; Spies, Fennema-Notestine, Archibald, Cherner, & Seedat, 2012; Troeman et al., 2011) , and may exacerbate HIV-related deficits. ...
brain alterations and immune recovery, with the largest increases in abnormal white matter and subcortical grey matter volumes evident in subjects with CD4+ T cell increases of at least 50 cells/μl (Fennema-Notestine ...
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Brain structure mediates the association between height and cognitive ability
[article]
<span title="2017-09-01">2017</span>
<i title="Cold Spring Harbor Laboratory">
bioRxiv
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<span class="release-stage" >pre-print</span>
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., Fennema-Notestine, C., Neale, M.C., Jak, A., Jernigan, T.L., Fischl, B., Franz, C.E., Lyons, M.J., Grant, M., Prom-Wormley, E., Seidman, L.J., Tsuang, M.T., Fiecas, M.J., Dale, A.M., Kremen, W.S., 2012 ...
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The bilingual effect on Boston Naming Test performance
<span title="2007-02-02">2007</span>
<i title="Cambridge University Press (CUP)">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/xvr5kau3hzbntoja7v53bdyqga" style="color: black;">Journal of the International Neuropsychological Society</a>
</i>
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Mental health outcomes in HIV and childhood maltreatment: a systematic review
<span title="2012-06-28">2012</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/6t2o5x3lszbsjevqwugrx5vzzu" style="color: black;">Systematic Reviews</a>
</i>
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High rates of childhood maltreatment have been documented in HIV-positive men and women.
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<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/2046-4053-1-30">doi:10.1186/2046-4053-1-30</a>
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Repetition priming with nonverbal stimuli in patients with dementia of the Alzheimer type
<span title="">1998</span>
<i title="American Psychological Association (APA)">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/eeplguwqcfcnne6r43rkybseme" style="color: black;">Neuropsychology</a>
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Perceptual repetition priming was examined in patients with dementia of the Alzheimer type (DAT) and normal control (NC) participants using a task involving the discrimination of geometric designs that had either a continuous ("closed") or discontinuous ("open") perimeter. With the open stimuli, the groups displayed significant and equivalent levels of priming after immediate repetition of the stimuli, whereas only the NC group primed significantly over a delay of three intervening items.
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<a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1037//0894-4105.12.1.43">doi:10.1037//0894-4105.12.1.43</a>
<a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/9460734">pmid:9460734</a>
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... r group demonstrated significant priming with the closed stimuli. Results indicate that under some conditions DAT patients can exhihit normal repetition priming with stimuli that do not have preexisting representations but that (due possibly to a deficiency in the level of steady-state cortical activation) this priming dissipates more rapidly in DAT patients than in NC participants. A number of studies have shown that patients with dementia of the Alzheimer type (DAT) are impaired on word-
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Cognitive phenotypes, brain morphometry and the detection of cognitive decline in preclinical AD
<span title="">2009</span>
<i title="Hindawi Limited">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/lplhrqfxibdapixms7fsblzldu" style="color: black;">Behavioural Neurology</a>
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findings have been partially attributed to differences in methodologies [47] , and a paucity of large-scale studies with sufficient sample sizes, or prospective longitudinal designs [21, 22] (see Fennema-Notestine ...
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Repetition priming with nonverbal stimuli in patients with dementia of the Alzheimer type
<span title="">1998</span>
<i title="American Psychological Association (APA)">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/eeplguwqcfcnne6r43rkybseme" style="color: black;">Neuropsychology</a>
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Perceptual repetition priming was examined in patients with dementia of the Alzheimer type (DAT) and normal control (NC) participants using a task involving the discrimination of geometric designs that had either a continuous ("closed") or discontinuous ("open") perimeter. With the open stimuli, the groups displayed significant and equivalent levels of priming after immediate repetition of the stimuli, whereas only the NC group primed significantly over a delay of three intervening items.
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... r group demonstrated significant priming with the closed stimuli. Results indicate that under some conditions DAT patients can exhihit normal repetition priming with stimuli that do not have preexisting representations but that (due possibly to a deficiency in the level of steady-state cortical activation) this priming dissipates more rapidly in DAT patients than in NC participants. A number of studies have shown that patients with dementia of the Alzheimer type (DAT) are impaired on word-
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Federated Web-accessible Clinical Data Management within an Extensible NeuroImaging Database
<span title="2010-06-22">2010</span>
<i title="Springer Nature">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/u22dt24i4vfrpip5iefcgkkzbi" style="color: black;">Neuroinformatics</a>
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Managing vast datasets collected throughout multiple clinical imaging communities has become critical with the ever increasing and diverse nature of datasets. Development of data management infrastructure is further complicated by technical and experimental advances that drive modifications to existing protocols and acquisition of new types of research data to be incorporated into existing data management systems. In this paper, an extensible data management system for clinical neuroimaging
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... ies is introduced: The Human Clinical Imaging Database (HID) and Toolkit. The database schema is constructed to support the storage of new data types without changes to the underlying schema. The complex infrastructure allows management of experiment data, such as image protocol and behavioral task parameters, as well as subject-specific data, including demographics, clinical assessments, and behavioral task performance metrics. Of significant interest, embedded clinical data entry and management tools enhance both consistency of data reporting and automatic entry of data into the database. The Clinical Assessment Layout Manager (CALM) allows users to create on-line data entry forms for use within and across sites, through which data is pulled into the underlying database via the generic clinical assessment management engine (GAME). Importantly, the system is designed to operate in a distributed environment, serving both human users and client applications in a service-oriented manner. Querying capabilities use a built-in multi-database parallel query builder/result combiner, allowing web-accessible queries within and across multiple federated databases. The system along with its documentation is open-source and available from the Neuroimaging Informatics Tools and Resource Clearinghouse (NITRC) site.
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Lexical and sentential priming in competition: Implications for two-stage theories of lexical access
<span title="">2001</span>
<i title="Cambridge University Press (CUP)">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/kq7pbys4ljd3vhwoyxftynl5la" style="color: black;">Applied Psycholinguistics</a>
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Fennema-Notestine, and a McDonnell-Pew Center for Cognitive Neuroscience Post-Doctoral Fellowship to Arturo Hernandez. ...
NIDCD Grant #2-ROI-DC00216-10), the grant "Aging and Bilingualism" (NIA Grant #5-R01-AG13474-02), National Science Foundation and McDonnell-Pew Center for Cognitive Neuroscience Graduate Fellowships to Christine ...
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