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Changes in the intracranial volume from early adulthood to the sixth decade of life: A longitudinal study [article]

Yaron Caspi, Rachel M. Brouwer, Hugo G. Schnack, Marieke E. van de Nieuwenhuijzen, Wiepke Cahn, Rene S. Kahn, Wiro J. Niessen, Aad van der Lugt, Hilleke Hulshoff Pol
2019 bioRxiv   pre-print
In conclusion, human intracranial volume does not stay constant during adulthood but instead shows small increases during young adulthood and decreases from the fourth decade of life.  ...  We report statistically significant increases in the ICV in adulthood until the fourth decade of life (average change +0.03%/y, or about 0.5 ml/y, at age 20), and decreases in the ICV afterward (-0.09%  ...  values from young adulthood to the sixth decade of life.  ... 
doi:10.1101/677898 fatcat:ezueg36nb5entob2inrbcdxcku

Changes in the intracranial volume from early adulthood to the sixth decade of life: A longitudinal study

Yaron Caspi, Rachel M. Brouwer, Hugo G. Schnack, Marieke E. van de Nieuwenhuijzen, Wiepke Cahn, René S. Kahn, Wiro J. Niessen, Aad van der Lugt, Hilleke Hulshoff Pol
2020 NeuroImage  
In conclusion, human intracranial volume does not stay constant during adulthood but instead shows small increase during young adulthood and a decrease thereafter from the fourth decade of life.  ...  We report statistically significant increases in the ICV in adulthood until the fourth decade of life (average change +0.03%/y, or about 0.5 ml/y, at age 20), and decreases in the ICV afterward (-0.09%  ...  Acknowledgments The authors would like to thank Hakim Achterberg, Marcel Koek, Adriaan Versteeg, Thomas Phil, Thomas Kroes, Baldur van Lew, Marcel Zwiers and Seyed Mostafa Kia for a collaboration within  ... 
doi:10.1016/j.neuroimage.2020.116842 pmid:32339774 fatcat:gfg5aalixnaqlcrtlr5ln46y7m

Ophthalmologic complications of meningomyelocele: a longitudinal study

A W Biglan
1990 Transactions of the American Ophthalmological Society  
Children with spina bifida should have frequent examinations by an ophthalmologist who is familiar with the diagnosis and management of the defects recorded in this study.  ...  Most of the problems are related to the hydrocephalus, which is caused by the coexisting Arnold-Chiari malformation.  ...  If hydrocephalus is present early in life, the head will enlarge. If glaucoma occurs early in life the eye will enlarge, and become buphthalmic.  ... 
pmid:2095031 pmcid:PMC1298598 fatcat:piyt4a6lnbbjpgn5ckiug4wosu

Life-Span Changes of the Human Brain White Matter: Diffusion Tensor Imaging (DTI) and Volumetry

L. T. Westlye, K. B. Walhovd, A. M. Dale, A. Bjornerud, P. Due-Tonnessen, A. Engvig, H. Grydeland, C. K. Tamnes, Y. Ostby, A. M. Fjell
2009 Cerebral Cortex  
Although the volumetric data supported protracted growth into the sixth decade, DTI indices plateaued early in the fourth decade across all tested regions and then declined slowly into late adulthood followed  ...  Tractwise and voxel-based analyses yielded regional differences in development and aging but did not provide ample evidence in support of a simple last-in-firstout hypothesis of life-span changes.  ...  28.6 Note: The FA values were computed as mean values in regions encompassing both the TBSS skeleton and the atlas-based tract. t 5 t value, F 5 F value, R 2 5 adjusted R 2 , age at maxima 5 age at LOESS  ... 
doi:10.1093/cercor/bhp280 pmid:20032062 fatcat:genhrhvwzvdobfa4dlkcy62tsi

Coupled changes in hippocampal structure and cognitive ability in later life

Devasuda Anblagan, Maria C. Valdés Hernández, Stuart J. Ritchie, Benjamin S. Aribisala, Natalie A. Royle, Iona F. Hamilton, Simon R. Cox, Alan J. Gow, Alison Pattie, Janie Corley, John M. Starr, Susana Muñoz Maniega (+3 others)
2018 Brain and Behavior  
Methods: In a longitudinal study of community-dwelling adults, we investigated whether there were coupled changes in hippocampal structure and verbal memory, working memory, and processing speed between  ...  Hippocampal structure was indexed by hippocampal volume, hippocampal volume as a percentage of intracranial volume (H_ICV), fractional anisotropy (FA), mean diffusivity (MD), and longitudinal relaxation  ...  A previous study showed that T1 declines throughout adolescence and early adulthood, achieving a minimum value in the fourth to sixth decade of life, and then T1 begins increasing (Cho, Jones, Reddick  ... 
doi:10.1002/brb3.838 pmid:29484252 pmcid:PMC5822578 fatcat:v4vkqkwqhzdatoha2if6wss2rm

Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study

Christopher A Lane, Josephine Barnes, Jennifer M Nicholas, Carole H Sudre, David M Cash, Thomas D Parker, Ian B Malone, Kirsty Lu, Sarah-Naomi James, Ashvini Keshavan, Heidi Murray-Smith, Andrew Wong (+13 others)
2019 Lancet Neurology  
High and increasing blood pressure from early adulthood into midlife seems to be associated with increased WMHV and smaller brain volumes at 69-71 years of age.  ...  Participants were from Insight 46, a neuroscience substudy of the ongoing longitudinal Medical Research Council National Survey of Health and Development, a birth cohort that initially comprised 5362 individuals  ...  Acknowledgments We are very grateful to those study members who helped in the design of the study through focus groups, and to the participants both for their contributions to Insight 46 and for their  ... 
doi:10.1016/s1474-4422(19)30228-5 pmid:31444142 pmcid:PMC6744368 fatcat:edrx63jygbakjjnjuw7xbw4sc4

The association of mid-to late-life systemic inflammation with white matter structure in older adults: The Atherosclerosis Risk in Communities Study

Keenan A. Walker, B. Gwen Windham, Melinda C. Power, Ron C. Hoogeveen, Aaron R. Folsom, Christie M. Ballantyne, David S. Knopman, Elizabeth Selvin, Clifford R. Jack, Rebecca F. Gottesman
2018 Neurobiology of Aging  
These results suggest that increasing and persistent inflammation in the decades spanning middle-to late-life may promote WM disease in older adults.  ...  Compared to the group with low CRP at all three visits, the group which transitioned from low to elevated CRP during midlife demonstrated greatest WMH volume and poorest WM microstructural integrity, after  ...  Acknowledgments The Atherosclerosis Risk in Communities Study is carried out as a collaborative study supported by National Heart, Lung, and Blood Institute contracts (HHSN268201100005C, HHSN268201100006C  ... 
doi:10.1016/j.neurobiolaging.2018.03.031 pmid:29702373 pmcid:PMC6010227 fatcat:oggkimhkszdlnlibjbtw7g5vgi

Corticolimbic Circuit Structure Moderates an Association Between Early Life Stress and Later Trait Anxiety

M. Justin Kim, Madeline J. Farber, Annchen R. Knodt, Ahmad R. Hariri
2019 NeuroImage: Clinical  
These structural properties of the corticolimbic circuit may capture a neural profile of relative resiliency to early life stress, especially against the negative effects of childhood adversity on later  ...  Here, we examined how individual variability in structural features of the corticolimbic circuit, which plays a key role in emotional reactivity, moderates the association between childhood adversity and  ...  Acknowledgments We thank the Duke Neurogenetics Study participants as well as the staff of the Laboratory of NeuroGenetics.  ... 
doi:10.1016/j.nicl.2019.102050 pmid:31677585 pmcid:PMC6838553 fatcat:tui3sbr27raohkuqprmeegw27e

Correlations among Brain Gray Matter Volumes, Age, Gender, and Hemisphere in Healthy Individuals

Yasuyuki Taki, Benjamin Thyreau, Shigeo Kinomura, Kazunori Sato, Ryoi Goto, Ryuta Kawashima, Hiroshi Fukuda, Yong He
2011 PLoS ONE  
Our study may contribute to clarifying the mechanism(s) of normal brain aging in each brain region.  ...  Analysis of global gray matter volume revealed a significant negative correlation between gray matter ratio (gray matter volume divided by intracranial volume) and age in both genders, and a significant  ...  Acknowledgments We would like to thank Drs. Kentaro Inoue and Ken Okada for collecting the data. Author Contributions  ... 
doi:10.1371/journal.pone.0022734 pmid:21818377 pmcid:PMC3144937 fatcat:fq7ngozuj5gwhmaecvgk6af6cm

Hominin life history: reconstruction and evolution

Shannen L. Robson, Bernard Wood
2008 Journal of Anatomy  
In this review we attempt to reconstruct the evolutionary history of hominin life history from extant and fossil evidence.  ...  We compare the life history variables of modern great apes and identify traits that are likely to be shared by the last common ancestor of Pan-Homo and those likely to be derived in hominins.  ...  Acknowledgements We thank Matthew Skinner for several of the figures and illustrations, and Robin Bernstein, Sarah Elton, Kristen Hawkes, Earl Keefe, and James O'Connell for helpful comments.  ... 
doi:10.1111/j.1469-7580.2008.00867.x pmid:18380863 fatcat:u3y4ankb35bpnmscxobjdv6e2y

Brain Morphometry and Cognitive Performance in Normal Brain Aging: Age- and Sex-Related Structural and Functional Changes

Yauhen Statsenko, Tetiana Habuza, Darya Smetanina, Gillian Lylian Simiyu, Liaisan Uzianbaeva, Klaus Neidl-Van Gorkom, Nazar Zaki, Inna Charykova, Jamal Al Koteesh, Taleb M. Almansoori, Maroua Belghali, Milos Ljubisavljevic
2022 Frontiers in Aging Neuroscience  
It is challenging to segregate normal brain aging from the accelerated one.ObjectiveTo work out a descriptive model of brain structural and functional changes in normal aging.Materials and MethodsBy using  ...  They should be viewed as signs of a disease. There is a sex difference in the speed and/or in the onset of the gray matter atrophy. It either starts earlier or goes faster in males.  ...  A steep increase in the volume of ventricles began in the fifth decade in men and in the sixth decade in women.  ... 
doi:10.3389/fnagi.2021.713680 pmid:35153713 pmcid:PMC8826453 fatcat:det7xklw6rgk3e3pni7gdkyala

Entorhinal Cortex Thickness across the Human Lifespan

Khader M. Hasan, Benson Mwangi, Bo Cao, Zafer Keser, Nicholas J. Tustison, Peter Kochunov, Richard E. Frye, Mirjana Savatic, Jair Soares
2015 Journal of Neuroimaging  
Here, we sought to fill this gap in knowledge by quantifying the ERC thickness in a very large cohort of subjects spanning nine decades of life.  ...  of ERC thickness in 1660 healthy controls ranging from 2 to 94 years of age.  ...  Acknowledgements This work is funded by the National Institutes of Health (NIH/NINDS R01-NS052505-04) and the Dunn Research Fund to K.M.H., NS046565 to R.E.F, NIMH Grant R01 MH 085667 and the Pat Rutherford  ... 
doi:10.1111/jon.12297 pmid:26565394 pmcid:PMC4826319 fatcat:m4pvo2y6u5hxhcyocrxncfo32y

Is Autosomal Dominant Polycystic Kidney Disease Becoming a Pediatric Disorder?

Stéphanie De Rechter, Luc Breysem, Djalila Mekahli
2017 Frontiers in Pediatrics  
As renal cyst formation and expansion begins early in life, frequently in utero, ADPKD should no longer be considered an adult-onset disease.  ...  Autosomal dominant polycystic kidney disease (ADPKD) affects 1 in 400 to 1,000 live births, making it the most common monogenic cause of renal failure.  ...  Importantly, mathematical models computing volume changes of solitary and multiple cysts in function of time show that cysts formed early in life, are the main contributors to the final total cyst volume  ... 
doi:10.3389/fped.2017.00272 pmid:29326910 pmcid:PMC5742347 fatcat:r6qcpt2gebdebmi5bxdyejjyqa

White Matter Changes of Neurite Density and Fiber Orientation Dispersion during Human Brain Maturation

Yi Shin Chang, Julia P. Owen, Nicholas J. Pojman, Tony Thieu, Polina Bukshpun, Mari L. J. Wakahiro, Jeffrey I. Berman, Timothy P. L. Roberts, Srikantan S. Nagarajan, Elliott H. Sherr, Pratik Mukherjee, Gaolang Gong
2015 PLoS ONE  
after the fourth decade of life.  ...  Our results suggest that the rise of FA during the first two decades of life is dominated by increasing NDI, while the fall in FA after the fourth decade is driven by the exponential rise of ODI that overcomes  ...  Acknowledgments We are grateful to all of the families at the participating Simons Variation in Individuals Project (Simons VIP) sites, as well as the Simons VIP working group (Simons VIP Consortium, Neuron  ... 
doi:10.1371/journal.pone.0123656 pmid:26115451 pmcid:PMC4482659 fatcat:khyfuld3bbgrdfemsnjhfqxjkm

Childhood self-control forecasts the pace of midlife aging and preparedness for old age

Leah S. Richmond-Rakerd, Avshalom Caspi, Antony Ambler, Tracy d'Arbeloff, Marieke de Bruine, Maxwell Elliott, HonaLee Harrington, Sean Hogan, Renate M. Houts, David Ireland, Ross Keenan, Annchen R. Knodt (+11 others)
2021 Proceedings of the National Academy of Sciences of the United States of America  
We studied the association between self-control and midlife aging in a population-representative cohort of children followed from birth to age 45 y, the Dunedin Study.  ...  The ability to control one's own emotions, thoughts, and behaviors in early life predicts a range of positive outcomes in later life, including longevity. Does it also predict how well people age?  ...  WMH volume is measured in Montreal Neurological Institute space, removing the influence of differences in brain volume and intracranial volume on WMH volume.  ... 
doi:10.1073/pnas.2010211118 pmid:33397808 pmcid:PMC7826388 fatcat:6l4mn7s5ojaw5e6bautgle4jwa
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