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Cervix Cancer Spatial Modelling for Brachytherapy Applicator Analysis

Peter Rogelj, Muhamed Barakovi´cbarakovi´c
2015 Informatica   unpublished
Standard applicators for cervix cancer brachytherapy (BT) do not always enable a sufficient radiation dose coverage of the target structure (HR-CTV).  ...  The aim of this study was to develop methodology for building models of the BT target from a cohort of cervix cancer patients, which would enable BT applicator testing.  ...  The obtained VP data was used for analysis and development of BT applicators for cervix cancer [12] .  ... 
fatcat:63cj445lxbg3rpbczbwbrpl3sy

Impact of heterogeneity-corrected dose calculation using a grid-based Boltzmann solver on breast and cervix cancer brachytherapy

Julia Hofbauer, Christian Kirisits, Alexandra Resch, Yingjie Xu, Alina Sturdza, Richard Pötter, Nicole Nesvacil
2016 Journal of Contemporary Brachytherapy  
(GBBS), and to evaluate the shielding effects of different cervix brachytherapy applicators.  ...  Material and methods: Calculations with TG-43 and Acuros were based on computed tomography (CT) retrospectively, for 10 cases of accelerated partial breast irradiation and 9 cervix cancer cases treated  ...  Disclosure The Department of Radiotherapy at the Medical University of Vienna receives financial and/or equipment support for research and educational purposes from Elekta AB and Varian Medical Systems  ... 
doi:10.5114/jcb.2016.59352 pmid:27257419 pmcid:PMC4873554 fatcat:vgove7qeqjcapkhqqmjmsrlmka

Magnetic Resonance Image Guided Brachytherapy

Kari Tanderup, Akila N. Viswanathan, Christian Kirisits, Steven J. Frank
2014 Seminars in Radiation Oncology  
Clinical improvements in cervix cancer outcomes have been linked to the application of repeated MRI for identification of residual tumor volumes during radiotherapy.  ...  The application of MRI-guided brachytherapy has demonstrated significant growth during the last two decades.  ...  Clinical outcome of MRI guided brachytherapy Cervix cancer Clinical outcome for MRI-guided brachytherapy in cervix cancer has been reported by several institutions (4; 5; 67-69).  ... 
doi:10.1016/j.semradonc.2014.02.007 pmid:24931089 pmcid:PMC4147854 fatcat:zcibiqmwtjgwpmiqjrxdcpgy3y

Does Change in the Effect of Source Strength of the High Dose Rate 192Iridium Radio-Isotope on Local Control and Late Normal Tissue Toxicity (Bladder and Rectum) in the Treatment of Carcinoma Cervix

K. Sudhakar, K. Gunaseelan, K. S. Reddy, K. Saravanan, N. V. Vinin
2014 International Journal of Medical Physics Clinical Engineering and Radiation Oncology  
Materials and Methods: One hundred and two cases of carcinoma cervix were included in the study.  ...  Aim: To analyse and assess the effect of dose rate of 192 ir-source strength on late complications and local control rate during treatment of carcinoma cervix.  ...  It also has been reported to have advantages of better spatial reproducibility and fixed applicator geometry [5] . Shang-Wen Chen et al., reported 5-year overall survival was 75% for all patients.  ... 
doi:10.4236/ijmpcero.2014.34027 fatcat:77ramiuyybeclecorzkmcbkb2e

WITHDRAWN: Image-guided navigation systems for interstitial brachytherapy

Yan-Yan Hu, Xiao-Ling Yu
2017 OncoTarget  
This article reviews the existing navigation systems and techniques for brachytherapy and discusses the relevant clinical applications.  ...  Prior to the navigation techniques with quantitative imaging feedback during the procedure, the safety and accuracy of interstitial brachytherapy mainly depended upon the operator's experience, spatial  ...  However, the weaknesses such as requirement for manual sketch, not applicable to all body parts, and not providing standard dose models for corresponding lesions limit their applications.  ... 
doi:10.18632/oncotarget.18965 fatcat:ubpr72egmjgpdfbi6muqboiclq

MRI assisted cervix cancer brachytherapy pre-planning, based on insertion of the applicator in para-cervical anaesthesia: preliminary results of a prospective study

Primoz Petric, Robert Hudej, Maja Music
2009 Journal of Contemporary Brachytherapy  
In six locally advanced cervix cancer patients, five days before the first brachytherapy fraction, tandem & ring applicator was inserted under para-cervical anaesthesia, MRI performed and applicator removed  ...  To report on preliminary results of a prospective study on MRI-assisted cervix cancer brachytherapy pre-planning.  ...  cervix cancer since August 2006.  ... 
pmid:27807460 pmcid:PMC5086485 fatcat:mhdrdh34y5dhppynvk7hefqn3i

Design and implementation of a film dosimetry audit tool for comparison of planned and delivered dose distributions in high dose rate (HDR) brachytherapy

Antony L Palmer, Chris Lee, Ailsa J Ratcliffe, David Bradley, Andrew Nisbet
2013 Physics in Medicine and Biology  
The brachytherapy applicator dosimetry test object consists of a near full-scatter water tank with applicator and film supports constructed of Solid Water, accommodating any typical cervix applicator.  ...  The phantom was funded by IPEM and will be used for a UK national brachytherapy dosimetry audit.  ...  Acknowledgments The authors gratefully acknowledge: Peter Pryce and colleagues in the engineering workshop at the Clatterbridge Cancer Centre for construction of the audit tool; the Institute of Physics  ... 
doi:10.1088/0031-9155/58/19/6623 pmid:24018542 fatcat:6ndpzx3pvrg3fgnooma626s2ua

Retrospective feasibility study of simultaneous integrated boost in cervical cancer using tomotherapy: the impact of organ motion and tumor regression

Fernanda G Herrera, Sharon Callaway, Ela Delikgoz-Soykut, Mehtap Coskun, Laetitia Porta, Jean-Yves Meuwly, Joao Soares-Rodrigues, Leonie Heym, Raphael Moeckli, Mahmut Ozsahin
2013 Radiation Oncology  
The Dice's similarity coefficient (DSC) was used to assess the spatial overlap of CTV-SIBs between scans. A cumulative dose-volume histogram modeled estimated delivered doses.  ...  Methods and materials: Ten patients treated with standard doses of CRT and brachytherapy were retrospectively re-planned using a helical Tomotherapy -SIB technique for the hypothetical scenario of this  ...  Acknowledgement Laurence Collette senior statistician EORTC for her advice on statistical methods. Author details  ... 
doi:10.1186/1748-717x-8-5 pmid:23286694 pmcid:PMC3551799 fatcat:ql4xajeqyfdfjlavn333hsljpy

SP-0118: Genetic tools for prediction of normal tissue response; Perspectives and obstacles

C.N. Andreassen
2013 Radiotherapy and Oncology  
DVH reduction models have shown some success in predicting clinical outcomes, but all spatial dosimetric information is lost.  ...  Interestingly, non-dosimetric factors were also included in this modelling and submandibular gland removal was shown to be an independent risk factor for xerostomia.  ...  Therefore brachytherapy tends to be most adopted as an alternative or additional modality to external beam delivery in the treatment of cancers in cervix, anus, rectum, head and neck, prostate, breast  ... 
doi:10.1016/s0167-8140(15)32424-5 fatcat:pzkn4v3sonhfnnmmasdm7fwxwq

SP-0117: Comorbidity

J. Andreyev
2013 Radiotherapy and Oncology  
DVH reduction models have shown some success in predicting clinical outcomes, but all spatial dosimetric information is lost.  ...  Interestingly, non-dosimetric factors were also included in this modelling and submandibular gland removal was shown to be an independent risk factor for xerostomia.  ...  Therefore brachytherapy tends to be most adopted as an alternative or additional modality to external beam delivery in the treatment of cancers in cervix, anus, rectum, head and neck, prostate, breast  ... 
doi:10.1016/s0167-8140(15)32423-3 fatcat:dzxljyfzundkje4oq42tcfpgue

Is 3D printing-gided three-dimensional brachytherapy suitable for cervical cancer: from one single research institute?

2020 European Journal of Gynaecological Oncology  
Conclusion: 3D printing model can well display relationship with the surrounding normal tissues and effectively guide doctors to conduct individualized brachytherapy for cervical cancer.  ...  Objective: To investigate the guidance value of 3D printing in brachytherapy for cervical cancer and its role in the doctorpatient communication.  ...  .: 2017J01222), We would like to express my gratitude to all those who helped me during the writing of this manuscript, Thanks to all the peer reviewers and editors for their opinions and sugges tions.  ... 
doi:10.31083/j.ejgo.2020.04.4932 fatcat:67v7rpmosjho7e54snv3gkdc2y

Endocervical ultrasound applicator for integrated hyperthermia and HDR brachytherapy in the treatment of locally advanced cervical carcinoma

Jeffery H. Wootton, I-Chow Joe Hsu, Chris J. Diederich
2011 Medical Physics (Lancaster)  
Existing technologies for thermal treatment of the cervix have limited spatial control or rapid energy falloff.  ...  Methods: Treatment planning images from 35 patients who underwent HDR brachytherapy for locally advanced cervical cancer were inspected to assess the dimensions of radiation clinical target volumes ͑CTVs͒  ...  The ultrasound applicators are housed within a custom catheter modeled after an endocervical brachytherapy tandem.  ... 
doi:10.1118/1.3512803 pmid:21452697 pmcid:PMC3033875 fatcat:tp2jhb25pjb5plrqzvopxgikti

Brachytherapy in the treatment of cervical cancer: a review

Mitchell Kamrava, Robyn Banerjee
2014 International Journal of Women's Health  
brachytherapy Intracavitary brachytherapy remains the most commonly practiced form of brachytherapy for cervical cancer. 30 A wide variety of commercially available applicators exists for intracavitary  ...  Applicator selection Brachytherapy for cervical cancer can be performed using an intracavitary, interstitial, or combination approach.  ... 
doi:10.2147/ijwh.s46247 pmid:24920937 pmcid:PMC4045176 fatcat:hya2r4nadjfbfgtk6hsqhxroji

Knowledge-Based Three-Dimensional Dose Prediction for Tandem-And-Ovoid Brachytherapy [article]

Katherina G. Cortes, Aaron Simon, Karoline Kallis, Jyoti Mayadev, Sandra Meyers, Kevin L. Moore
2021 arXiv   pre-print
Purpose: To develop a knowledge-based voxel-wise dose prediction system using a convolution neural network for high-dose-rate brachytherapy cervical cancer treatments with a tandem-and-ovoid (T&O) applicator  ...  Conclusion: 3D knowledge-based dose predictions for T&O brachytherapy provide accurate voxel-level and DVH metric estimates.  ...  Acknowledgements We thank Kelly Kisling, Xenia Ray, and Aaron Babier for helpful discussions.  ... 
arXiv:2102.11384v1 fatcat:lbhthso2drg33mmbmvsdh4jx2a

CT Based 3-Dimensional Treatment Planning of Intracavitary Brachytherapy for Cancer of the Cervix : Comparison between Dose-Volume Histograms and ICRU Point Doses to the Rectum and Bladder

Natasha Hashim, Zulaikha Jamalludin, Ngie Min Ung, Gwo Fuang Ho, Rozita Abdul Malik, Vincent Chee Ee Phua
2014 Asian Pacific Journal of Cancer Prevention  
For some developed country, image-guided brachytherapy is the new gold standard for cervix cancer brachytherapy.  ...  Tan LT and colleagues from Addenbrooke has reported their 3 years experience of chemoradiotherapy for cervical cancer with CT-based image-guided HDR brachytherapy using the tandem-ring applicator (Tan  ... 
doi:10.7314/apjcp.2014.15.13.5259 fatcat:vzgjqszqmneh3fvchckxbglxwa
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