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Utilização do Sistema Sonar (bandinha digital) na avaliação auditiva comportamental de lactentes

Helenice Yemi Nakamura, María Cecília Marconi Pinheiro Lima, Vanda Maria Gimenes Gonçalves
2006 Pró-Fono  
(Nakamura, 1996) .  ...  (Nakamura, 2005) . (A) (B) (C) (A) FIGURE 1. Sonar System graph A: sound box support; B: hinge to fix the support (possibilitates the modification of height); C: metallic tube.  ... 
doi:10.1590/s0104-56872006000100008 pmid:16625872 fatcat:tb4dl3zozfartewljnvc4a7xjq

Abietatrienes diterpenoids from Sagittaria montevidensis SSP Montevidensis

Clara M. A. Tanaka, Vanessa S. C. O. Radke, Cleuza C. da Silva, Celso V. Nakamura, Pollyanna L. de Oliveira, Lucilia Kato, Cecília M. A. de Oliveira
2010 Química Nova  
Recebido em 1/10/08; aceito em 14/7/09; publicado na web em 25/11/09 The antimicrobial properties of the hexane, hexane/EtOAc and methanol fractions of the fresh petioles of Sagittaria montevidensis ssp montevidensis (Alismataceae) were evaluated against fungi and Gram-negative and Gram-positive bacteria. A new abietatrienetype diterpenoid, 3β,7α-dihydroxi-abieta-8,11,13-triene and the known 3β-hydroxy-abieta-8,11,13-trien-7-one were isolated from the most active fraction tested and the
more » ... es of these compounds were elucidated by data including IR, EIMS, and 1D and 2D NMR spectra.
doi:10.1590/s0100-40422010000100006 fatcat:ggkh63db25h5jejut63pdhwx54

Experiences of homonegativity and sexual risk behaviour in a sample of Latino gay and bisexual men

Nadine Nakamura, Maria Cecilia Zea
2010 Culture, Health and Sexuality  
This study examines the relationship between homonegativity, racism, and poverty on HIV risk related behaviour with an internet-based sample of 226 Latino gay and bisexual men. Participants had a median level of education at "graduate school level or higher" and a median monthly income in the $1600-$2400 range. Income and education in this sample are higher than participants in most other studies of Latino gay and bisexual men, providing information about HIV risk in a previously understudied
more » ... gment of the population. Three negative binomial regressions were employed to predict unprotected receptive anal intercourse, unprotected insertive anal intercourse and unprotected sex under the influence of drugs in the past 30 days, with education, Latino acculturation, income, experiences of racism, and homonegativity as predictors. Greater experiences of homonegativity, fewer experiences of racism, lower income, and higher Latino acculturation predicted unprotected receptive anal intercourse. Only lower Latino acculturation predicted unprotected insertive anal intercourse. Greater experiences of homonegativity, higher income, and higher Latino acculturation predicted unprotected sex under the influence of drugs. This suggests that experiences of homonegativity have a detrimental impact on health behaviours. Future research should aim to further understand the relationship between experiencing homonegativity and engaging in risky sexual behaviour. Keywords Sexual risk; men who have sex with men; drug use; homonegativity
doi:10.1080/13691050903089961 pmid:19637067 pmcid:PMC3646569 fatcat:nu7o6yrmuzd2xbf7p72p762eum

Arthroscopic osteochondral autologous transplantation for the treatment of osteochondritis dissecans of the femoral head

Soshi Uchida, Hajime Utsunomiya, Eisaburo Honda, Shiho Kanezaki, Eiichiro Nakamura, Cecilia Pascual-Garrido, Akinori Sakai
2017 SICOT-J  
Osteochondritis dissecans (OCD) of the femoral head is an unusual cause of hip pain. It can be associated with other intra-articular pathologies including: acetabular labral tears or bone deformities such as Legg-Calve-Perthes Disease (LCPD). In this article, we propose a modern surgical technique using an arthroscopic antegrade and retrograde osteochondral autologous transplantation (OAT) procedure for assessing and treating OCD lesions of the femoral head.
doi:10.1051/sicotj/2016044 pmid:29792398 pmcid:PMC5966838 fatcat:2evszwnsabhbbhonmjjkn4o3cy

UV curable liquid crystalline acrylates used as retardation film for reflective guest-host liquid crystal display

Fumiaki Yamada, Cecilia Hellermark, Hajime Nakamura
2000 ITE Technical Report  
Refiective liquid crystal display is suitable for portable devices because the pewer consumption is lower by not using a backlight. It is recognized that the key fbr the better quality display are the refiectivity and the contrast ratio. Guest-host type liquid crystal display .with quarteT-lambda plate (QWP) is expected to have high contrast and refle ¢ tivity. We fabricated a quarter lambda plate using several photo polymerizable liquid crystal mQnomers and evaluated their optical performances.
doi:10.11485/itetr.24.58.0_189 fatcat:5wio4hmx7zggzmjylzhziorudi

ESTIMATIVA DE VALORES ECONOMIZADOS COM A CESSAÇÃO DO TABAGISMO

Cecília Fanha Dornelles, Matheo Augusto Morandi Stumpf, Maki Caroline Nakamura, Samuel Cavalli Kluthcovsky, Bruna Trevisan Vernizi, Erildo Vicente Muller, Ana Claudia Garabeli Cavalli Kluthcovsky
2019 Revista Interdisciplinar de Estudos em Saúde  
<p class="resumo">Este estudo objetivou estimar o valor financeiro que o tabagista economizaria ao longo dos anos, caso depositasse em uma aplicação financeira o valor utilizado na compra de cigarros a cada mês. Trata-se de um estudo transversal e quantitativo, com dados de 119 pacientes atendidos em um projeto de extensão universitária, entre 2015 e 2016. Foram analisadas as informações sobre a idade, gênero, data do início do tratamento e número de cigarros consumidos por dia. A partir do
more » ... r que seria depositado mensalmente em caderneta de poupança, por paciente, caso deixasse de fumar, foram calculadas as estimativas dos valores brutos que seriam economizados em 10 anos e segundo a expectativa de vida. A comparação entre os gêneros foi realizada pelo teste de Mann-Whitney e o nível de significância foi de 5%. Foi observado que, independente da faixa etária, o valor a ser depositado mensalmente, que corresponderia ao gasto mensal com o cigarro, foi muito semelhante, variando de R$170,39 a R$197,41. O valor bruto que seria economizado ao longo da vida é considerável, especialmente na faixa etária mais jovem, chegando a mais de dois milhões de reais. Nenhuma variável na comparação entre os gêneros apresentou diferença significativa, demonstrando que o valor depositado mensalmente e economizado ao longo da vida seria semelhante em ambos os grupos. Os resultados obtidos devem ser apresentados à população tabagista servindo como incentivo para a cessação do tabagismo.</p><p class="resumo"><strong>Palavras-chave</strong>: Tabagismo. Economia. Abandono do uso de tabaco.</p><p class="resumo"> </p><h3><strong>ESTIMATION OF VALUES SAVED WITH CESSATION OF SMOKING</strong></h3><p class="resumo"> </p><div><p class="abstractCxSpFirst"><strong>ABSTRACT: </strong>This study aim to estimate the financial value that a smoker would save along years if he deposited the value used in the purchase of cigarettes each month in a saving account. Cross-sectional quantitative study, with 119 patients attended in a university extension project, between 2015 and 2016. Age, gender, treatment initiation date and number of cigarettes consumed per day were analysed. From the value that is monthly deposited in savings account, per patient, if the smoker stopped smoking, was calculated an estimative of the gross values that would be saved in 10 years and according to life expectancy. Mann-Whitney test was used for gender comparison and the significance level used was 5%. It was observed that, regardless of the age group, the amount to be deposited monthly, which corresponds to the monthly expenditure with cigarette, was very similar, from R$ 170,39 to R$ 197,41. The gross amount that is saved along life is considerable, especially in the younger age group, reaching more than two million reais. There was no variable in the comparison between the genders that had statistic difference, demonstrating that the value deposited monthly and the value saved calculated by life expectancy were similar in both groups. The results obtained should be disclosed to smokers and serve as another incentive for smoking cessation.</p><p class="abstractCxSpLast"><strong>Keywords: </strong>Tobacco use disorders. Economics. Tobacco use cessation.</p></div>
doi:10.33362/ries.v7i2.1422 fatcat:wzn2spjqlfcrxn2wjufvc6bgwy

Antitrypanosomal Activity of Novel Benzaldehyde-Thiosemicarbazone Derivatives from Kaurenoic Acid †

Shirani K. Haraguchi, Adriano A. Silva, Gentil J. Vidotti, Phercyles V. Dos Santos, Francielle P. Garcia, Raissa B. Pedroso, Celso V. Nakamura, Cecília M. A. De Oliveira, Cleuza C. Da Silva
2011 Molecules  
A series of new thiosemicarbazones derived from natural diterpene kaurenoic acid were synthesized and tested against the epimastigote forms of Trypanosoma cruzi to evaluate their antitrypanosomal potential. Seven of the synthesized thiosemicarbazones were more active than kaurenoic acid with IC₅₀ values between 2-24.0 mM. The o-nitro-benzaldehyde-thiosemicarbazone derivative was the most active compound with IC₅₀ of 2.0 mM. The results show that the structural modifications accomplished
more » ... the antitrypanosomal activity of these compounds. Besides, the thiocyanate, thiosemicarbazide and the p- methyl, p-methoxy, p-dimethylamine, m-nitro and o-chlorobenzaldehyde-thiosemicarbazone derivatives displayed lower toxicity for LLMCK₂ cells than kaurenoic acid, exhibing an IC₅₀ of 59.5 mM.
doi:10.3390/molecules16021166 pmid:21270733 pmcid:PMC6259918 fatcat:72ty7kmblff63c7xgjts5wq5gy

A Modularized Cognitive-Behavioral Intervention for Water Phobia in an Adolescent with Childhood-Onset Schizophrenia

Brad J. Nakamura, Jason Schiffman, Cecilia W. Lam, Kimberly D. Becker, Bruce F. Chorpita
2006 Child & family behavior therapy (Print)  
Nakamura, MA (  ... 
doi:10.1300/j019v28n03_02 fatcat:boy4v7ddf5hznoqpu6v4nxqxze

Initial characterization, dosimetric benchmark and performance validation of Dynamic Wave Arc

Manuela Burghelea, Dirk Verellen, Kenneth Poels, Cecilia Hung, Mitsuhiro Nakamura, Jennifer Dhont, Thierry Gevaert, Robbe Van den Begin, Christine Collen, Yukinori Matsuo, Takahiro Kishi, Viorica Simon (+2 others)
2016 Radiation Oncology  
Dynamic Wave Arc (DWA) is a clinical approach designed to maximize the versatility of Vero SBRT system by synchronizing the gantry-ring noncoplanar movement with D-MLC optimization. The purpose of this study was to verify the delivery accuracy of DWA approach and to evaluate the potential dosimetric benefits. Methods: DWA is an extended form of VMAT with a continuous varying ring position. The main difference in the optimization modules of VMAT and DWA is during the angular spacing, where the
more » ... A algorithm does not consider the gantry spacing, but only the Euclidian norm of the ring and gantry angle. A preclinical version of RayStation v4.6 (RaySearch Laboratories, Sweden) was used to create patient specific wave arc trajectories for 31 patients with various anatomical tumor regions (prostate, oligometatstatic cases, centrally-located non-small cell lung cancer (NSCLC) and locally advanced pancreatic cancer-LAPC). DWA was benchmarked against the current clinical approaches and coplanar VMAT. Each plan was evaluated with regards to dose distribution, modulation complexity (MCS), monitor units and treatment time efficiency. The delivery accuracy was evaluated using a 2D diode array that takes in consideration the multi-dimensionality of DWA during dose reconstruction. Results: In centrally-located NSCLC cases, DWA improved the low dose spillage with 20 %, while the target coverage was increased with 17 % compared to 3D CRT. The structures that significantly benefited from using DWA were proximal bronchus and esophagus, with the maximal dose being reduced by 17 % and 24 %, respectively. For prostate and LAPC, neither technique seemed clearly superior to the other; however, DWA reduced with more than 65 % of the delivery time over IMRT. A steeper dose gradient outside the target was observed for all treatment sites (p < 0.01) with DWA. Except the oligometastatic cases, where the DWA-MCSs indicate a higher modulation, both DWA and VMAT modalities provide plans of similar complexity. The average ɣ (3 % /3 mm) passing rate for DWA plans was 99.2 ± 1 % (range from 96.8 to 100 %). Conclusions: DWA proven to be a fully functional treatment technique, allowing additional flexibility in dose shaping, while preserving dosimetrically robust delivery and treatment times comparable with coplanar VMAT.
doi:10.1186/s13014-016-0633-7 pmid:27130434 pmcid:PMC4850693 fatcat:porq5a5p4rhefjqhfejhva6gxq

Enhanced immunization techniques to obtain highly specific monoclonal antibodies

Rodrigo de Almeida, Cecília Naomi Nakamura, Marina de Lima Fontes, Elenice Deffune, Sérgio Luis Felisbino, Ramon Kaneno, Wagner José Fávaro, Athanase Billis, Marcel Otavio Cerri, Ana Marisa Fusco-Almeida, Maria José Mendes Giannini, Andrei Moroz
2017 mAbs  
Despite fast advances in genomics and proteomics, monoclonal antibodies (mAbs) are still a valuable tool for areas such as the evolution of basic research in stem cells and cancer, for immunophenotyping cell populations, diagnosing and prognosis of diseases, and for immunotherapy. To summarize different subtractive immunization approaches successfully used for the production of highly specific antibodies, we identified scientific articles in NCBI PubMed using the following search terms:
more » ... ive immunization, monoclonal antibody, tolerization, neonatal, high-zone tolerance, masking immunization. Patent records were also consulted. From the list of results, we included all available reports, from 1985 to present, that used any enhanced immunization technique to produce either polyclonal or monoclonal antibodies. Our examination yielded direct evidence that these enhanced immunization techniques are efficient in obtaining specific antibodies to rare epitopes, with different applications, such as to identify food contaminants or tumor cells.
doi:10.1080/19420862.2017.1331804 pmid:28581886 pmcid:PMC5800380 fatcat:xnkqcl62g5gltdejt5i2ivf4my

Associations between nucleosome phasing, sequence asymmetry, and tissue-specific expression in a set of inbred Medaka species

Yoichiro Nakatani, Cecilia C. Mello, Shin-ichi Hashimoto, Atsuko Shimada, Ryohei Nakamura, Tatsuya Tsukahara, Wei Qu, Jun Yoshimura, Yutaka Suzuki, Sumio Sugano, Hiroyuki Takeda, Andrew Fire (+1 others)
2015 BMC Genomics  
Transcription start sites (TSSs) with pronounced and phased nucleosome arrays downstream and nucleosome-depleted regions upstream of TSSs are observed in various species. Results: We have characterized sequence variation and expression properties of this set of TSSs (which we call "Nucleocyclic TSSs") using germline and somatic cells of three medaka (Oryzias latipes) inbred isolates from different locations. We found nucleocyclic TSSs in medaka to be associated with higher gene expression and
more » ... aracterized by a clear boundary in sequence composition with potentially-nucleosome-destabilizing A/T-enrichment upstream (p < 10 −60 ) and nucleosome-accommodating C/G-enrichment downstream (p < 10 −40 ) that was highly conserved from an ancestor. A substantial genetic distance between the strains facilitated the in-depth analysis of patterns of fixed mutations, revealing a localization-specific equilibrium between the rates of distinct mutation categories that would serve to maintain the conserved sequence anisotropy around TSSs. Downstream of nucleocyclic TSSs, C to T, T to C, and other mutation rates on the sense strand increased around first nucleosome dyads and decreased around first linkers, which contrasted with genomewide mutational patterns around nucleosomes (p < 5 %). C to T rates are higher than G to A rates around nucleosome associated with germline nucleocyclic TSS sites (p < 5 %), potentially due to the asymmetric effect of transcription-coupled repair. Conclusions: Our results demonstrate an atypical evolutionary process surrounding nucleocyclic TSSs.
doi:10.1186/s12864-015-2198-5 pmid:26584643 pmcid:PMC4653950 fatcat:ibcy4o7srzfg7aj5rwgd3khfoy

Antiprotozoal alkaloids from Psychotria prunifolia (Kunth) Steyerm

Kato Lucilia, Cecília M. A. de Oliveira, Emiret O. Faria, Laryssa C. Ribeiro, Brenda G. Carvalho, Cleuza C. da Silva, Ivânia T. A. Schuquel, Silvana M. O. Santin, Celso V. Nakamura, Elisandra A. Britta, Nathielle Miranda, Amadeu H. Iglesias (+1 others)
2012 Journal of the Brazilian Chemical Society  
A continuidade do estudo fitoquímico de P. prunifolia com a análise dos extratos etanólicos obtidos a partir de suas raízes e galhos levou ao isolamento de cinco alcaloides indol-b-carbolínicos dos quais, dois derivados, o 10-hidróxi-iso-deppeaninol e o N-óxido-10-hidróxi-antirhina são descritos pela primeira vez. As estruturas foram determinadas por análise de técnicas espectroscópicas de IV, EMAR e RMN ( 1 H e 13 C, 1D e 2D). A avaliação da atividade frente à Leishmania amazonensis e
more » ... ma cruzi, mostrou que os extratos brutos e os alcaloides 14-oxoprunifoleína e estrictosamida inibiram as formas promastigotas de L. amazonensis, com valores de CI 50 de 16,0 e 40,7 mg per mL, respectivamente. The continuity of the phytochemical study of crude extracts of P. prunifolia's roots and branches led to the isolation of five indole-b-carboline alkaloids. Among them, the 10-hydroxyiso-deppeaninol and N-oxide-10-hydroxy-antirhine derivatives are described here for the first time. The structures were achieved through 1D and 2D NMR, IR and HRMS analyses. The branches and roots crude extracts and the alkaloids 14-oxoprunifoleine and strictosamide showed selective activity against L. amazonensis, with IC 50 values of 16.0 and 40.7 mg per mL, respectively.
doi:10.1590/s0103-50532012000200024 fatcat:semq4ugglres3j2j22kywb33qq

ANÁLISE DA CESSAÇÃO DO TABAGISMO DURANTE E APÓS O TRATAMENTO E FATORES ASSOCIADOS

Ana Claudia Garabeli Cavalli Kluthcovsky, Cecília Fanha Dornelles, Erildo Vicente Muller, Allan Catarino Kiska Torrani, Alisson Ferreira Pupulim, Carlos Rory Pucci Filho, Maki Caroline Nakamura, Matheo Augusto Morandi Stumpf
2019 Revista Interdisciplinar de Estudos em Saúde  
<p class="resumo">O tabagismo possui relação com diversas doenças e seu tratamento traz benefícios para fumantes ativos e passivos. O objetivo desse estudo foi analisar os resultados do tratamento em pacientes tabagistas e possíveis fatores associados. Estudo retrospectivo com análise dos dados de 62 pacientes tratados em um projeto de extensão universitária. Foram coletados dados socioeconômicos, clínicos, referentes ao tabagismo e sobre os resultados da cessação do tabagismo durante o período
more » ... de tratamento e após o tratamento (tempo médio de 8,0<span style="text-decoration: underline;">+</span>2,0 meses após o início do tratamento). Para as análises estatísticas foram utilizados os testes Qui-quadrado e Exato de Fisher, com nível de significância de 5%. Durante o período de tratamento 51,6% dos pacientes pararam de fumar e 37,1% reduziram o número de cigarros por dia. Dos 54 pacientes que responderam aos contatos telefônicos após o tratamento, 31,5% permaneciam sem fumar, 27,8% estavam fumando número reduzido de cigarros por dia e 16,6% apresentaram recaída. Frequência de presenças aos encontros durante o tratamento inferior a 5 vezes (p&lt;0,001) e grau de dependência à nicotina elevado ou muito elevado (p=0,03) foram associados a não parar de fumar durante o tratamento. Observou-se uma boa proporção de cessação do tabagismo durante e após o tratamento. Incentivo deve ser dado para que os pacientes compareçam aos encontros de tratamento, com atenção especial para aqueles com grau de dependência à nicotina elevado ou muito elevado.</p><p class="resumo"><strong>Palavras-chave</strong>: Tabagismo. Abandono do uso do tabaco. Produtos para o abandono do uso de tabaco. Programa Nacional de Controle do Tabagismo.</p><p class="resumo"> </p><h3>ANALYSIS OF SMOKE CESSATION DURING AND AFTER TREATMENT AND ASSOCIATED FACTORS</h3><div><p class="abstractCxSpFirst"><strong>ABSTRACT: </strong>Smoking is related to several diseases and its treatment brings benefits to active and passive smokers. This study aimed to analyze the treatment results in smokers and possible associated factors. A retrospective study was carried out, with data from 62 patients treated in a university extension project<strong>. </strong>Socioeconomic, clinical and smoking data were collected. Data on smoking cessation outcomes were also collected during the treatment period and after treatment (mean time 8.0<span style="text-decoration: underline;">+</span>2,0 months after initiation of treatment). Statistical analyzes were performed using the Chi-square test and Fisher Exact test. The level of significance was 5%. During the treatment period 51.6% of the patients stopped smoking and 37.1% reduced the number of cigarettes per day. Out of the 54 patients who responded to telephone contacts after treatment, 31.5% remained smoking-free, 27.8% were smoking less cigarettes per day and 16.6% relapsed. At least 5 times during treatment (p&lt;0,001) and high or very high nicotine dependence level (p=0,03) were associated with non-stop smoking during treatment. A good proportion of smoking cessation was observed during and after treatment. An encouragement must be given for patients to attend treatment meetings, with special attention for those with high or very high nicotine dependence.</p><p class="abstractCxSpLast"><strong>Keywords: </strong>Tobacco use disorder. Tobacco use cessation. Tobacco use cessation products. National Program of Tobacco Control.</p></div>
doi:10.33362/ries.v8i1.1450 fatcat:jasvwyt5djfenjul4ojcd6k3tu

Multiple Tolerization Reduces Antibody Binding Against Tolerogen Cells: Implications for the Production of Monoclonal Antibodies

Rodrigo de Almeida, Cecília Naomi Nakamura, Marina de Lima Fontes, Julia Paiola da Silva, Matheus Bertanha, Elenice Deffune, Ana Marisa Fusco-Almeida, Andrei Moroz
2018 Monoclonal antibodies in immunodiagnosis and immunotherapy  
We report an immunization technique that can update the production of monoclonal antibodies (mAbs): the multiple tolerization subtractive immunization (MTSI). A total of 10 BALB/C mice were used. Animals in group 1 received one inoculation of RWPE-1 cells (nontumoral), followed by cyclophosphamide, and then received serial inoculations of nonirradiated PC3 cells (tumoral). Animals in group 2 received our MTSI protocol, as follows: one inoculation of RWPE-1 cells, followed by cyclophosphamide
more » ... ). This whole tolerization step was repeated three other times, with 14-day intervals between the last Cy exposure and the next RWPE-1 cell inoculation. Finally, the animals received the same nonirradiated PC3 cell exposure as group 1. Blood was taken from each animal, and their polyclonal sera individually tested against the nontumoral RWPE-1 cells in flow cytometry. We found out that, after the MTSI was employed, the serum of the immunized animals, in group 2, contained considerably less antibodies that reacted against the tolerogenic cells, compared with the serum of the animals that underwent regular subtractive immunization. We showed that, by repeating the tolerization cycles, the polyclonal antibodies produced by mice have a reduced specificity toward common/immunodominant epitopes present at nontumoral cells, and thus this technique can be readily used by others in studies involving murine mAb protocols.
doi:10.1089/mab.2017.0055 pmid:29708868 fatcat:exjitsniu5dwlbgezrytjss6t4

Comparative study between fructose 1-6 bisphosphate and histidine-tryptophan-ketoglutarate in liver preservation in rats submitted to total cold ischemia

Fernanda Bombonato Smecellato, Lucas Ricardo Benfatti Marsilli, Julia Eico Nakamura, Maria Cecília Jordani, Paulo Roberto Barbosa Évora, Orlando Castro-e-Silva
2020 Acta Cirurgica Brasileira  
Purpose To compare Fructose-1,6-Bisphosphate (FBP) to Histidine-Tryptophan-Ketoglutarate (HTK) in liver preservation at cold ischemia. Methods Male rats (Sprague-Dawley: 280-340g) divided into three groups (n=7): Control; Fructose-1,6-bisphosphate (FBP); Histidine-Tryptophan-Ketoglutarate (HTK). Animals underwent laparotomy-thoracotomy for perfusion of livers with saline. Livers were removed and deposited into solutions. Mitochondria were isolated to determine State 3 (S3), State 4 (S4),
more » ... tory Control Ratio (RCR) and Swelling (S). Liver enzymes (AST, ALT, LDH) were determined in solution. At tissue, Malondialdehyde (MDA) and Nitrate (NOx) were determined. All parameters were analyzed at 0.6 and 24 hours of hypothermic preservation. Statistics analysis were made by Mann-Whitney test (p<0.05). Results Regarding ALT, there was a difference between FBP-6h/HTK-6h, lower in HTK. Regarding AST, there was a significant difference between FBP-24h/HTK-24h, lower in FBP. Regarding NOx, there was a difference between 0h and 6h, as well as 0h and 24h for both solutions. Regarding S3, there was a significant difference in 24h compared to Control-0h for both solutions, and a significant difference between FBP-6h/FBP-24h. Regarding S4, there was a difference between Control-0h/HTK-24h and FBP-24h/HTK-24h, higher in HTK. There was a difference between Control-0h/FBP-24h for Swelling, higher in FBP. Conclusion Fructose-1,6-Bisphosphate showed better performance at nitrate and aspartate aminotransferase compared to histidine-tryptophan-ketoglutarate.
doi:10.1590/s0102-865020200060000003 pmid:32667586 fatcat:th7kn7exkjdnhfozz6ntxzemfq
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