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CNAnova: a new approach for finding recurrent copy number abnormalities in cancer SNP microarray data

Sergii Ivakhno, Simon Tavaré
2010 Computer applications in the biosciences : CABIOS  
Results: We present a novel approach for finding regions of recurrent copy number aberrations, called CNAnova, from Affymetrix SNP 6.0 array data.  ...  The availability of high-density, large sample-size SNP array datasets makes the identification of recurrent copy number changes in cancer, an important issue that can be addressed using the cross-sample  ...  DISCUSSION We have presented a novel framework, CNAnova, for using unsegmented SNP microarray data to identify recurrent copy number aberrations in cancer.  ... 
doi:10.1093/bioinformatics/btq145 pmid:20403815 fatcat:zzc3m4e3zfgtlmnhfywmlt5aci