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and practical complexities facing the medical diagnostic, prognostic and monitoring field today. ... This year's symposium focussed on the following conference themes: How to develop and apply prediction models and diagnostic tests High-dimensional data and genetic prediction Machine learning for evaluation ... Background: Analysis using random effects linear models is the established method used in biological variability studies to attribute the observed variability arising from between-patient differences, ...doi:10.1186/s41512-021-00094-7 pmid:33789755 fatcat:qpy3vxjtifezzirbuaevywfz3y