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Broadband changes in the cortical surface potential track activation of functionally diverse neuronal populations

Kai J Miller, Christopher J Honey, Dora Hermes, Rajesh PN Rao, Marcel denNijs, Jeffrey G Ojemann
2014 NeuroImage  
These broadband changes are shown to be a generic correlate of local cortical function across a variety of brain areas and behavioral tasks.  ...  We illustrate a general principal of electrical potential measurements from the surface of the cerebral cortex, by revisiting and reanalyzing experimental work from the visual, language and motor systems  ...  The data indicate that this broadband spectral signature is robustly linked to function across cortical areas and behaviors, thereby generically tracking the activation of cortical populations with high  ... 
doi:10.1016/j.neuroimage.2013.08.070 pmid:24018305 pmcid:PMC4347924 fatcat:z4knumbtfbceza6vvxgdrldlqi

Dynamic Modulation of Local Population Activity by Rhythm Phase in Human Occipital Cortex During a Visual Search Task

Kai J. Miller, Dora Hermes, Christopher J. Honey, Mohit Sharma, Rajesh P. N. Rao, Marcel den Nijs, Eberhard E. Fetz, Terrence J. Sejnowski, Adam O. Hebb, Jeffrey G. Ojemann, Scott Makeig, Eric C. Leuthardt
2010 Frontiers in Human Neuroscience  
Comparison of visual search epochs with a blank screen baseline revealed changes in the raw potential, the amplitude of rhythmic activity, and in the decoupled broadband spectral amplitude.  ...  We quantified the interaction between broadband spectral change and brain rhythms on a second-to-second basis in electrocorticographic (ECoG) measurement of brain surface potentials in five human subjects  ...  Close inspection of the figures IntroductIon Recent electrocorticographic (ECoG) and local field potential (LFP) measurements have revealed a link between neuronal population activity and changes in  ... 
doi:10.3389/fnhum.2010.00197 pmid:21119778 pmcid:PMC2990655 fatcat:ae5pn6d37zcmbhqdo74nzfre7a

Developmental overproduction of cortical superficial neurons impairs adult auditory cortical processing [article]

Mirna Merkler, Nancy Y Ip, Shuzo Sakata
2022 bioRxiv   pre-print
Here we show that the overproduction of cortical superficial neurons leads to hyposensitivity to auditory stimuli in mice.  ...  Still, little is known about how the overproduction of cortical neurons during development affects cortical processing and behavior in later life.  ...  Acknowledgements This work was supported by the BBSRC (BB/M009050X/1) and Horizon2020-RIA (DEEPER, 101016787) to SS, and the Area of Excellence Scheme of the University Grants Committee (AoE/M-604/16)  ... 
doi:10.1101/2022.02.09.479758 fatcat:vgqvjgzvrbe3pa6yruhgtizcli

Dynamic Network Communication as a Unifying Neural Basis for Cognition, Development, Aging, and Disease

Bradley Voytek, Robert T. Knight
2015 Biological Psychiatry  
A complete model of cognitive function and dysfunction must account for a diversity of factors including, but not limited to, brain structure and genetics, rapid neuronal temporal dynamics and neuroplasticity  ...  Our theory is predicated on evidence that neuronal oscillations bias the probability of spiking such that action potentials are more likely to occur during periods of interregional oscillatory coherence  ...  All authors report no biomedical financial interests or potential conflicts of interest.  ... 
doi:10.1016/j.biopsych.2015.04.016 pmid:26005114 pmcid:PMC4443259 fatcat:akkl7bmeova5tgjvuqhqhg4cba

State-dependent and cell type-specific temporal processing in auditory thalamocortical circuit

Shuzo Sakata
2016 Scientific Reports  
While neurons in both areas showed diverse response proiles, auditory cortical neurons typically showed a large onset response followed by brief suppression and rebound activation regardless of cortical  ...  Although the functional role of this quicker rebound activity in auditory processing is uncertain, one functional implication is the improvement of temporal tuning (Fig. 7) .  ...  Author Contributions S.S. performed all experiments and data analysis, and wrote the manuscript. Additional Information Supplementary information accompanies this paper at  ... 
doi:10.1038/srep18873 pmid:26728584 pmcid:PMC4700423 fatcat:jd6mf7j2yrci3k64jgbyy6vf4m

A Switch and Wave of Neuronal Activity in the Cerebral Cortex During the First Second of Conscious Perception

Wendy X. Herman, Rachel E Smith, Sharif I Kronemer, Rebecca E Watsky, William C Chen, Leah M. Gober, George J Touloumes, Meenakshi Khosla, Anusha Raja, Corey L Horien, Elliot C. Morse, Katherine L. Botta (+5 others)
2017 Cerebral Cortex  
Surface maps and k-means clustering analysis showed initial activation of visual cortex for both perceived and non-perceived stimuli.  ...  Faces were presented at individually titrated visual threshold for 9 subjects while measuring broadband 40-115 Hz gamma power in a total of 1621 intracranial electrodes widely distributed in both hemispheres  ...  We thank Rachel Denison, Marisa Carrasco-Queijeiro, and David Heeger for making us aware of the similarity of our results to modulation of the SSVEP.  ... 
doi:10.1093/cercor/bhx327 pmid:29194517 fatcat:3nlalbjk55bwdfathmhqmevgki

Stimulus-dependent spiking relationships with the EEG

Adam C. Snyder, Matthew A. Smith
2015 Journal of Neurophysiology  
Linking spontaneous activity of single cortical neurons and the underlying functional architecture. Science 286: 1943-1946, 1999. van Burik M, Peters M. EEG and implanted sources in the brain.  ...  Frequency-band coupling in surface EEG reflects spiking activity in monkey visual cortex. Neuron 64: 281-289, 2009. Yoshioka T, Levitt JB, Lund JS.  ...  of Pittsburgh.  ... 
doi:10.1152/jn.00427.2015 pmid:26108954 pmcid:PMC4556847 fatcat:wvvymgzokbe6nk3sfegk5d67r4

Laminar-dependent effects of cortical state on auditory cortical spontaneous activity

Shuzo Sakata, Kenneth D. Harris
2012 Frontiers in Neural Circuits  
Cortical circuits spontaneously generate coordinated activity even in the absence of external inputs. The character of this activity depends on cortical state.  ...  We investigated how state affects the organization of spontaneous activity across layers of rat auditory cortex in vivo, using juxtacellular recording of morphologically identified neurons and large-scale  ...  Nevertheless, the details of how state affects patterns of cortical population activity are not yet fully clear, for example, with regards to how state changes affect the activity of different cortical  ... 
doi:10.3389/fncir.2012.00109 pmid:23267317 pmcid:PMC3527822 fatcat:kghq476jtfa4xmsl4h7rc4lwta

Arousal dependent modulation of thalamo-cortical functional interaction

Iain Stitt, Zhe Charles Zhou, Susanne Radtke-Schuller, Flavio Fröhlich
2018 Nature Communications  
Thus, neuromodulators may play a role in dynamically sculpting the patterns of thalamo-cortical functional interaction that underlie visual processing.  ...  Furthermore, the presentation of naturalistic video stimuli induces thalamo-cortical network states closely resembling epochs of high arousal in the absence of visual input.  ...  I.S., Z.C.Z., and F.F. wrote the paper. All authors contributed to the discussion of the results and revision of the manuscript.  ... 
doi:10.1038/s41467-018-04785-6 pmid:29941957 pmcid:PMC6018110 fatcat:x5kb4f2k65etvah4urmrs7mtla

Sensory overamplification in layer 5 auditory corticofugal projection neurons following cochlear nerve synaptic damage

Meenakshi M. Asokan, Ross S. Williamson, Kenneth E. Hancock, Daniel B. Polley
2018 Nature Communications  
We track daily changes in sound processing using chronic widefield calcium imaging of L5 axon terminals on the dorsal cap of the IC in awake, adult mice.  ...  Sustained potentiation of excitatory ACtx projection neurons that innervate multiple limbic and subcortical auditory centers may underlie hyperexcitability and aberrant functional coupling of distributed  ...  Acknowledgements We thank the UAB Vector Core, GENIE Program, the Janelia Farm Research Campus and Penn Vector Core in the Gene Therapy Program of the University of Pennsylvania for providing the GCaMP6s  ... 
doi:10.1038/s41467-018-04852-y pmid:29941910 pmcid:PMC6018400 fatcat:a75faphxxnbxtj46ri6ere3vuu

Multimodal in vivo recording using transparent graphene microelectrodes illuminates spatiotemporal seizure dynamics at the microscale [article]

Nicolette Driscoll, Richard E Rosch, Brendan B. Murphy, Arian Ashourvan, Ramya Vishnubhotla, Olivia O. Dickens, A.T. Charlie Johnson, Kathryn A. Davis, Brian Litt, Danielle S Bassett, Hajime Takano, Flavia Vitale
2020 bioRxiv   pre-print
This integrated analysis of multimodal data reveals otherwise hidden state transitions in the spatial and temporal progression of acute seizures.  ...  progression of ictal electrophysiology is linked to the spatial evolution of the recruited seizure core.  ...  Any opinions, findings, conclusions, or recommendations expressed in this material are those of the authors and do not necessarily reflect the views of the National Science Foundation.  ... 
doi:10.1101/2020.06.04.134189 fatcat:bdax4w3gt5grzm7h27drq7xijq

Multimodal in vivo recording using transparent graphene microelectrodes illuminates spatiotemporal seizure dynamics at the microscale

Nicolette Driscoll, Richard E. Rosch, Brendan B. Murphy, Arian Ashourvan, Ramya Vishnubhotla, Olivia O. Dickens, A. T. Charlie Johnson, Kathryn A. Davis, Brian Litt, Danielle S. Bassett, Hajime Takano, Flavia Vitale
2021 Communications Biology  
This integrated analysis of multimodal data reveals otherwise hidden state transitions in the spatial and temporal progression of acute seizures.  ...  progression of ictal electrophysiology is linked to the spatial evolution of the recruited seizure core.  ...  Acknowledgements This material is based upon work supported by the National Science Foundation Graduate Research Fellowship Program (DGE-1845298 to Driscoll, Murphy) and was carried out in part at the  ... 
doi:10.1038/s42003-021-01670-9 pmid:33514839 fatcat:sy4nsoxe6nhqtemdgif7oao564

Selective Participation of Single Cortical Neurons in Neuronal Avalanches

Timothy Bellay, Woodrow L. Shew, Shan Yu, Jessica J. Falco-Walter, Dietmar Plenz
2021 Frontiers in Neural Circuits  
Neuronal avalanches are scale-invariant neuronal population activity patterns in the cortex that emerge in vivo in the awake state and in vitro during balanced excitation and inhibition.  ...  Our results support the view that avalanches represent the selective, scale-invariant formation of neuronal groups in line with the idea of Hebbian cell assemblies underlying cortical information processing  ...  ACKNOWLEDGMENTS We thank members of the Plenz lab for discussions and Drs. Richard Saunders (NIMH) and Andy Mitz (NIMH) for help with the nonhuman primate surgery and electrophysiological recording.  ... 
doi:10.3389/fncir.2020.620052 pmid:33551757 pmcid:PMC7862716 fatcat:zrd5apueebcivmpa6oqihwdkre

Frontal Cortex Activation Causes Rapid Plasticity of Auditory Cortical Processing

D. E. Winkowski, S. Bandyopadhyay, S. A. Shamma, P. O. Kanold
2013 Journal of Neuroscience  
How or whether activity in frontal areas can influence activity and sensory processing in A1 and the detailed changes occurring in A1 on the level of single neurons and in neuronal populations remain uncertain  ...  The source of a signal to A1 that triggers these changes is suspected to be in frontal cortical areas.  ...  First, the observed diversity in response change may be a consequence of the local heterogeneity Figure 11 . Discrimination performance as a function of population size.  ... 
doi:10.1523/jneurosci.0180-13.2013 pmid:24227723 pmcid:PMC3828466 fatcat:kztqjs5dpnennioohe3amditki

Laminar analysis of slow wave activity in humans

Richárd Csercsa, Balázs Dombovári, Dániel Fabó, Lucia Wittner, Loránd Erőss, László Entz, András Sólyom, György Rásonyi, Anna Szűcs, Anna Kelemen, Rita Jakus, Vera Juhos (+10 others)
2010 Brain  
To elucidate the intracortical neuronal mechanisms of slow wave activity in humans, novel, laminar multichannel microelectrodes were chronically implanted into the cortex of patients with drug-resistant  ...  Neuronal firing in the up-state was sparse and the average discharge rate of single cells was less than expected from animal studies.  ...  Since cortical neuronal populations and synaptic inputs are organized into distinct layers, these recordings allowed us to resolve the cortical generators underlying slow wave activity in humans.  ... 
doi:10.1093/brain/awq169 pmid:20656697 pmcid:PMC3105490 fatcat:5ybdtcnigbfgxko4v2vxuymdz4
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