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BioNetCAD: design, simulation and experimental validation of synthetic biochemical networks

Stéphanie Rialle, Liza Felicori, Camila Dias-Lopes, Sabine Pérès, Sanaâ El Atia, Alain R. Thierry, Patrick Amar, Franck Molina
<span title="2010-07-13">2010</span> <i title="Oxford University Press (OUP)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/4r72gbmtcrde5no3fwwogjs3cu" style="color: black;">Computer applications in the biosciences : CABIOS</a> </i> &nbsp;
Results: We describe a methodology for the construction of synthetic biochemical networks based on three main steps: design, simulation and experimental validation.  ...  We demonstrate with a case study that BioNetCAD can rationalize and reduce further experimental validation during the construction of a biochemical network.  ...  Finally, the network can be experimentally validated. Fig Fig. 2.Step-wise network design/implementation and simulation using BioNetCAD.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1093/bioinformatics/btq409">doi:10.1093/bioinformatics/btq409</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/20628073">pmid:20628073</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC2935418/">pmcid:PMC2935418</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/jkdaga2qvbejjhh47iuhszjc2i">fatcat:jkdaga2qvbejjhh47iuhszjc2i</a> </span>
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