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Big GABA: Edited MR spectroscopy at 24 research sites

Mark Mikkelsen, Peter B. Barker, Pallab K. Bhattacharyya, Maiken K. Brix, Pieter F. Buur, Kim M. Cecil, Kimberly L. Chan, David Y.-T. Chen, Alexander R. Craven, Koen Cuypers, Michael Dacko, Niall W. Duncan (+48 others)
<span title="">2017</span> <i title="Elsevier BV"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/sa477uo7lveh7hchpikpixop5u" style="color: black;">NeuroImage</a> </i> &nbsp;
Nevertheless, implementations of GABA-edited MRS remain diverse across research sites, making comparisons between studies challenging.  ...  This large-scale multi-vendor, multi-site study seeks to better understand the factors that impact measurement outcomes of GABA-edited MRS.  ...  Results GABA-edited MRS data were successfully acquired at all 24 sites.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2017.07.021">doi:10.1016/j.neuroimage.2017.07.021</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28716717">pmid:28716717</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5700835/">pmcid:PMC5700835</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/t5ernqj6s5cdfhq2twugxt5jjm">fatcat:t5ernqj6s5cdfhq2twugxt5jjm</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20191118094944/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5700835&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/cb/83/cb83fd1d9164dbd74d1bbd89ae4051a55e020d24.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1016/j.neuroimage.2017.07.021"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> elsevier.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700835" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Feasibility of Measuring GABA Levels in the Upper Brainstem in Healthy Volunteers Using Edited MRS

Yulu Song, Tao Gong, Richard A. E. Edden, Guangbin Wang
<span title="2020-08-14">2020</span> <i title="Frontiers Media SA"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/7qi7czvcwfgankg6qiypfrijvm" style="color: black;">Frontiers in Psychiatry</a> </i> &nbsp;
The MEGA-PRESS sequence was used to edit GABA signal from a 10x25x30 mm3 voxel in the upper brain stem.  ...  The GABA+ levels were 2.66 ± 0.75 i.u. in the upper brainstem of healthy volunteers, ranging from 1.50 to 4.40 i.u.  ...  In spite of the relatively unfavorable anatomy, the linewidth achieved (median 7.8 Hz) is comparable to that seen in parietal lobe of the Big GABA multi-site study (mean 7.7 Hz (31)).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3389/fpsyt.2020.00813">doi:10.3389/fpsyt.2020.00813</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/32922319">pmid:32922319</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7456914/">pmcid:PMC7456914</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/a3abv25omrh7bnyzvkplkmtfeq">fatcat:a3abv25omrh7bnyzvkplkmtfeq</a> </span>
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The trajectory of cortical GABA levels across the lifespan: An individual participant data meta-analysis of edited MRS studies [article]

Eric C Porges, Greg Jensen, Brent Foster, Richard A E Edden, Nicolaas A J Puts
<span title="2020-07-24">2020</span> <i title="Cold Spring Harbor Laboratory"> bioRxiv </i> &nbsp; <span class="release-stage" >pre-print</span>
GABA is the principal inhibitory neurotransmitter in the human brain and can be measured with Magnetic Resonance Spectroscopy (MRS).  ...  Conflicting accounts report decreases and increases in cortical GABA levels across the lifespan.  ...  The most widely used edited MRS technique is MEGA-PRESS (Mescher et al., 1998) , in which a GABA-selective editing pulse at 1.9 ppm is applied in half of the experiment (edit-ON).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/2020.07.23.218792">doi:10.1101/2020.07.23.218792</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/cpzgoofh55aifhh5zbjdybyt6a">fatcat:cpzgoofh55aifhh5zbjdybyt6a</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20201103040240/https://www.biorxiv.org/content/biorxiv/early/2020/07/24/2020.07.23.218792.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/37/9d/379d9b345d661a5ba8d5b06e1fcb0b892ec61e8e.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1101/2020.07.23.218792"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> biorxiv.org </button> </a>

Autoregulation of neuronal activity by presynaptic GABA ARs

Sheyla Mejia-Gervacio, Alain Marty
<span title="2006-09-01">2006</span> <i title="The Physiological Society"> Physiology News </i> &nbsp;
David was passionate about research and during his early career made seminal contributions to the field of capillary permeability, studying microvascular permeability in the isolated perfused gastric mucosa  ...  glycolytic metabolism at these sites.  ...  The depolarization of the axon induces GABA release which binds back to receptors located near the release site in the axon.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.36866/pn.64.19">doi:10.36866/pn.64.19</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/x2zopbut7vcvrm76v3orwdogmy">fatcat:x2zopbut7vcvrm76v3orwdogmy</a> </span>
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Suppression and facilitation of human neural responses

Michael-Paul Schallmo, Alexander M Kale, Rachel Millin, Anastasia V Flevaris, Zoran Brkanac, Richard AE Edden, Raphael A Bernier, Scott O Murray
<span title="2018-01-29">2018</span> <i title="eLife Sciences Publications, Ltd"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/en4qj5ijrbf5djxx7p5zzpjyoq" style="color: black;">eLife</a> </i> &nbsp;
that evokes behavioral suppression and facilitation, and combining five different methodologies (behavioral psychophysics, computational modeling, functional MRI, pharmacology, and magnetic resonance spectroscopy  ...  , (2) neural suppression and facilitation in the motion-selective area MT mirror perception, but strong suppression also occurs in earlier visual areas, and (3) suppression is not primarily driven by GABA-mediated  ...  resonance spectroscopy (MRS).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.7554/elife.30334">doi:10.7554/elife.30334</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/29376822">pmid:29376822</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5812713/">pmcid:PMC5812713</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/f4pkjrziinhalaoqzi5xf62ao4">fatcat:f4pkjrziinhalaoqzi5xf62ao4</a> </span>
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An Update of the Classical and Novel Methods Used for Measuring Fast Neurotransmitters During Normal and Brain Altered Function

Victor Castro, Carmen Valenzuela, Juan Sanchez, Kenia Pena, Silvia Perez, Jorge Ibarra, Alberto Villagran
<span title="2015-02-17">2015</span> <i title="Bentham Science Publishers Ltd."> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/4puludp4rrgqjn6gqz5233oagy" style="color: black;">Current Neuropharmacology</a> </i> &nbsp;
Immediate response of the brain to environmental conditions is related with the release of the fast acting neurotransmission by glutamate (Glu), γ-aminobutyric acid (GABA) and acetylcholine (ACh) through  ...  biosensor the drawback of temporal resolution has been improved considerably, however other inconveniences have merged, such as stability, reproducibility and the lack of reliable biosensors mainly for GABA  ...  There are three approaches to resolve GABA signals by MRS: (1) using an editing method, which includes J-difference editing, like the MEGA-PRESS (J-difference edited point-resolved spectroscopy) method  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.2174/1570159x13666141223223657">doi:10.2174/1570159x13666141223223657</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/25977677">pmid:25977677</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4428024/">pmcid:PMC4428024</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/meb2k7kqebcjfkwpq64zvzjbo4">fatcat:meb2k7kqebcjfkwpq64zvzjbo4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190222174756/http://pdfs.semanticscholar.org/3ad9/fccc61f138f7eaa0a24fe39d2d1786f4b4e1.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/3a/d9/3ad9fccc61f138f7eaa0a24fe39d2d1786f4b4e1.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.2174/1570159x13666141223223657"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428024" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Pain Perception, Brain Connectivity, and Neurochemistry in Healthy, Capsaicin-Sensitive Subjects

Stefanie Heba, Matthias Sczesny-Kaiser, Kirsten Sucker, Jürgen Bünger, Thomas Brüning, Martin Tegenthoff, Tobias Schmidt-Wilcke, Carlo Cavaliere
<span title="2020-10-28">2020</span> <i title="Hindawi Limited"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/7swofhydobailpabrdytoscy2a" style="color: black;">Neural Plasticity</a> </i> &nbsp;
Edden and his group for the permission to utilize (RAEE) and their continuous helpful support in the GABA-edited magnetic resonance spectroscopy.  ...  Thus, GABA+ in this study refers to GABA including macromolecules. MRS sessions were scheduled so as to avoid the effects of frequency drift on GABA+-edited MRS [38, 39] .  ...  First, we chose the SMN as it conveys sensory and nociceptive input and, therein, opted for the thalamus being the central hub at a precortical stage as magnetic resonance spectroscopy (MRS) target.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1155/2020/9125913">doi:10.1155/2020/9125913</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33178262">pmid:33178262</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7644335/">pmcid:PMC7644335</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/jtcykgk5gnhyth67za2v62ftje">fatcat:jtcykgk5gnhyth67za2v62ftje</a> </span>
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Proton Magnetic Resonance Spectroscopy of the Central Nervous System [chapter]

Evanthia Kousi, Ioannis Tsougos, Kapsalaki Eftychi
<span title="2013-01-09">2013</span> <i title="InTech"> Novel Frontiers of Advanced Neuroimaging </i> &nbsp;
It is obvious that 1 H-MRS may aid in the determination of cerebral metastases origin, nevertheless, further research is needed to determine the exact role of proton MR spectroscopy in the identification  ...  This is reflected by more effective water suppression and improved baseline separation of Jcoupled metabolites such as glutamate, glutamine and GABA, without the need of sophisticated spectral editing  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5772/53892">doi:10.5772/53892</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/trfmtqcmdbflrb5qvkl5tadmze">fatcat:trfmtqcmdbflrb5qvkl5tadmze</a> </span>
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Speaker Abstracts

<span title="">2006</span> <i title="Informa UK Limited"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/outlkxphnzf2zjcoogyjlaf7ky" style="color: black;">International journal of psychiatry in clinical practice</a> </i> &nbsp;
inducible genes and fluorescent proteins to specific organelles such as mitochondria in astrocytes and neurons, in vitro and vivo imaging of Ca 2+ fluxes and NADH formation in cells and brain and 13C-NMR spectroscopy  ...  The initial increase in activity was observed at 5-30 min, followed by a decrease at 1 h, and returning to an increase at 4-24 h.  ...  The AQP4 mRNA expression remained unchanged at 1 h after injury, but a marked decreased at 12 and 24 h after injury (p < 0.05).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1080/13651500601027547">doi:10.1080/13651500601027547</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/24941153">pmid:24941153</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/zsibfd337rdzrj4dizujozsmbu">fatcat:zsibfd337rdzrj4dizujozsmbu</a> </span>
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Role of Hybrid Brain Imaging in Neuropsychiatric Disorders

Amer Burhan, Nicole Marlatt, Lena Palaniyappan, Udunna Anazodo, Frank Prato
<span title="2015-12-04">2015</span> <i title="MDPI AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/abr6zdbfebblxlzh436eqtiagi" style="color: black;">Diagnostics</a> </i> &nbsp;
Circumstantial evidence from MR spectroscopy (MRS) studies indicates that in early stages of schizophrenia, a glutamatergic excess may be seen, which later evolves into a state of glutamatergic deficit  ...  Combining imaging techniques, such as hybrid imaging, will be able to capture the "big picture" of the disease rather than offering only a single pixel at a time; a common result from single modality techniques  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/diagnostics5040577">doi:10.3390/diagnostics5040577</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/26854172">pmid:26854172</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC4728476/">pmcid:PMC4728476</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/jg22ndpmmbaihpn6dr3uo3io2e">fatcat:jg22ndpmmbaihpn6dr3uo3io2e</a> </span>
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Strategies for sensing neurotransmitters with responsive MRI contrast agents

Goran Angelovski, Éva Tóth
<span title="">2017</span> <i title="Royal Society of Chemistry (RSC)"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/qoebttzoxbfgviecxmhjrua4eu" style="color: black;">Chemical Society Reviews</a> </i> &nbsp;
The financial support from the Max Planck Society, CNRS, the Agence Nationale de Recherche, and academic research support program of Région Centre France (project ENZY-NEURO) is gratefully acknowledged  ...  Taking advantage of common NMR spectroscopy principles, neurotransmitters can be directly monitored by means of resolving their 1 H or 13 C spectra, resulting in magnetic resonance spectroscopy (MRS)  ...  MRS measurements need to be performed at high magnetic fields in order to increase sensitivity and resolution.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1039/c6cs00154h">doi:10.1039/c6cs00154h</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/28059423">pmid:28059423</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/roco5istrbandk27xdq57xfppi">fatcat:roco5istrbandk27xdq57xfppi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20190223030913/http://pdfs.semanticscholar.org/3ea1/1484d1e532b234d0cb92d82b73bb4c17b576.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/3e/a1/3ea11484d1e532b234d0cb92d82b73bb4c17b576.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1039/c6cs00154h"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>

Epilepsy Treatment: A Futurist View

Michael Privitera
<span title="">2017</span> <i title="American Epilepsy Society"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/luknhofbpbhu5nzftjpwxx724m" style="color: black;">Epilepsy Currents</a> </i> &nbsp;
Evidence from our human-based research has generated some support for epileptogenic networks using three disparate techniques: microdialysis, 7T MR spectroscopy, and electrophysiological connectivity.  ...  Regarding subcortical/cortical networks NAA/Cr levels, an indicator of mitochondrial function and thus energetics can be measured in the human brain using 7T MR spectroscopy.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5698/1535-7597.17.4.204">doi:10.5698/1535-7597.17.4.204</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/29225520">pmid:29225520</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC5716109/">pmcid:PMC5716109</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/zz56bz2tkfe4dd6pzwhliulol4">fatcat:zz56bz2tkfe4dd6pzwhliulol4</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200211124532/http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5716109&amp;blobtype=pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/47/3c/473cfc9a8b7d5f63de2fb7a14d325977f345275f.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.5698/1535-7597.17.4.204"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> Publisher / doi.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716109" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

The Potential of Metabolomics in the Diagnosis of Thyroid Cancer

Margarida Coelho, Luis Raposo, Brian J. Goodfellow, Luigi Atzori, John Jones, Bruno Manadas
<span title="2020-07-24">2020</span> <i title="MDPI AG"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/3loumxx7kzamnlu4h6x3xoz6ay" style="color: black;">International Journal of Molecular Sciences</a> </i> &nbsp;
This review considers the current results in thyroid cancer biomarker research with a focus on metabolomics.  ...  Technique Method Study site Sample Study design Altered metabolites Reference NMR MRS Spatially resolved information Non-invasive method 8 TC vs. 5 CTR Ch ↑ [46] MRS Non-invasive  ...  (MR) and mass spectrometry (MS).  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/ijms21155272">doi:10.3390/ijms21155272</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/32722293">pmid:32722293</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC7432278/">pmcid:PMC7432278</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/24dv4m6ojrfc5jfizyloe5p2oe">fatcat:24dv4m6ojrfc5jfizyloe5p2oe</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210716051704/https://iris.unica.it/retrieve/handle/11584/304388/432234/ijms-21-05272%20review%20tiroide.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/d2/3c/d23cad6760744d4fbfaf548f6383545bb8dc6a4a.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.3390/ijms21155272"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="unlock alternate icon" style="background-color: #fb971f;"></i> mdpi.com </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432278" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Advances in neuroimaging to support translational medicine in dementia

Thomas Edmund Cope, Rimona Sharon Weil, Emrah Düzel, Bradford C Dickerson, James Benedict Rowe
<span title="2021-02-10">2021</span> <i title="BMJ"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/hy257cksnngbdoh3z3erevh7h4" style="color: black;">Journal of Neurology, Neurosurgery and Psychiatry</a> </i> &nbsp;
Higher MRI field strengths open up the possibility of richer applications of spectroscopy, with signal to noise ratios sufficient for measurement of GABA in patients. 21 Quantitative susceptibility mapping  ...  The transmitter imaging is 7-Tesla MR Spectroscopy (image courtesy of Murley et al). 50 The activity images are 7-Tesla auditory fMRI and source-resolved evoked magnetoencephalography responses from superior  ...  JBR has performed consultancies with Biogen, UCB, Asceneuron, WAVE, Astex, SVHealth; has received research grants from AZ-Medimmune, Lilly, Janssen; and is an editor at Brain.  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1136/jnnp-2019-322402">doi:10.1136/jnnp-2019-322402</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/33568448">pmid:33568448</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC8862738/">pmcid:PMC8862738</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/kfzojf7vpncq7pgln7xiaue324">fatcat:kfzojf7vpncq7pgln7xiaue324</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20210213213753/https://jnnp.bmj.com/content/jnnp/92/3/263.full.pdf" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/4e/0a/4e0a3cf15d3da9fdf410727856bf69f3d3da5bb7.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1136/jnnp-2019-322402"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> bmj.org </button> </a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8862738" title="pubmed link"> <button class="ui compact blue labeled icon button serp-button"> <i class="file alternate outline icon"></i> pubmed.gov </button> </a>

Parallel Session Abstracts

<span title="">2012</span> <i title="Wiley"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/cskrqvzzhrarnjxoboevl3dd6u" style="color: black;">Acta Obstetricia et Gynecologica Scandinavica</a> </i> &nbsp;
Quantitative measurements of GABA levels in the occipital cortex by proton magnetic resonance spectroscopy ( 1 H-MRS) showed a decrease in GABA levels from the follicular to the luteal phase among healthy  ...  Purdy at The Scripps Research Institute, La Jolla, CA, USA (Purdy et al., 1990) .  ... 
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/j.1600-0412.2012.01435_1.x">doi:10.1111/j.1600-0412.2012.01435_1.x</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/22676222">pmid:22676222</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/7df7hkytgjfsvp5ywpe372x6vi">fatcat:7df7hkytgjfsvp5ywpe372x6vi</a> </span>
<a target="_blank" rel="noopener" href="https://web.archive.org/web/20200320095959/http://umu.diva-portal.org/smash/get/diva2:458846/FULLTEXT01" title="fulltext PDF download" data-goatcounter-click="serp-fulltext" data-goatcounter-title="serp-fulltext"> <button class="ui simple right pointing dropdown compact black labeled icon button serp-button"> <i class="icon ia-icon"></i> Web Archive [PDF] <div class="menu fulltext-thumbnail"> <img src="https://blobs.fatcat.wiki/thumbnail/pdf/28/96/289686cee883f69c4051811e8564ec4c2e01513e.180px.jpg" alt="fulltext thumbnail" loading="lazy"> </div> </button> </a> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1111/j.1600-0412.2012.01435_1.x"> <button class="ui left aligned compact blue labeled icon button serp-button"> <i class="external alternate icon"></i> Publisher / doi.org </button> </a>
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