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BN++ – A Biological Information System
2006
Journal of Integrative Bioinformatics
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BN++ is based on a comprehensive and extensible object model (BioCore), which has been implemented as a C++ framework, a Java class library, and a relational database. ...
We illustrate the usefulness of BN++ with a few select example applications.Availability: BN++ is open source software available from our website at www.bnplusplus.org. ...
Acknowledgements The authors would like to thank Thomas Schäfer and Marite Sirava for their work on the BN++ project. We are further grateful to Dr. ...
doi:10.1515/jib-2006-34
fatcat:cyefsqltzbh7bgghndsq77gkze
BN and BN oxide nanosheets based nanosensor for paracetamol adsorption: a first principles simulation
2014
Mexican Journal of Materials Science and Engineering
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The paracetamol molecule promotes also a decrease of the reactivity parameter, which is crucial for biological applications of these systems. ...
That is, these functionalized 2D systems yields appropriate conditions for field emission and they may be used as sensors of such pharmaceutical compound. ...
biological applications. ...
doaj:376a921c11a143578eb3d337398e960c
fatcat:tdg6mfp5ezaxrg3q5qjdk5b6oa
Electrophilic Aromatic Substitution of a BN Indole
2010
Journal of the American Chemical Society
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We report the first examples of a "BN-fused" indole, and we demonstrate that this new family of unnatural indole derivatives undergoes electrophilic aromatic substitution (EAS) reactions with the same ...
X-Ray structural analysis between BN indole and classic indole highlights significant differences in bond distances, in particular for bonds associated with the boron atom. NIH Public Access ...
The bicyclic N-t-Bu-BN-indole 2 consists of a 6-membered 1,2-dihydro-1,2-azaborine heterocycle 14,15 and a lsy@uorgon.edu. Supporting Information Available. ...
doi:10.1021/ja107312u
pmid:21043508
pmcid:PMC2990470
fatcat:ruljl24jyjhd5er7gw7lkjo3ui
Abstract analysis of pathways using the BN++ software framework
2007
BMC Systems Biology
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analysis of pathways using the BN++ software framework ...
With BN++, especially its C++ framework, we presented such a system [2] . In contrast to databases (e.g. ...
However, the sheer amount and heterogeneity of the data pose a major challenge and call for an integrative system, allowing to manage all this information. ...
doi:10.1186/1752-0509-1-s1-p24
fatcat:aymxqsb43fdg7fs2mqv6qwypee
Suppression of 1/f Noise in Near-Ballistic h-BN-Graphene-h-BN Heterostructure Field-Effect Transistors
[article]
2015
arXiv
pre-print
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The device channel was implemented with a single layer graphene encased between two layers of hexagonal boron nitride. ...
We have investigated low-frequency 1/f noise in the boron nitride - grapheme - boron nitride heterostructure field - effect transistors on Si/SiO2 substrates (f is a frequency). ...
A more informative characteristic of 1/f noise level in two-dimensional (2D) materials is the noise spectral density normalized to the device channel area, which we 3 | P a g e denote as parameter =(S ...
arXiv:1506.04083v1
fatcat:yxus4lj5pvf6jbnizm5eluqiwq
Suppression of 1/f noise in near-ballistic h-BN-graphene-h-BN heterostructure field-effect transistors
2015
Applied Physics Letters
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Figure 4(a) shows the noise amplitude in our h-BN-G-h-BN HFET as a function of V GS -V D (V D is the Dirac voltage). ...
Second, the stamp with PPC was brought into contact with the h-BN layer on a substrate using a micromanipulator. ...
doi:10.1063/1.4926872
fatcat:gmkydveyera3rh2jsvwpqgwoma
Use of a geographic information system to explore spatial variation in pathogen virulence and the implications for biological control of locusts and grasshoppers
2007
Agricultural and Forest Entomology
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The aim of the present study is to enhance the utility of this model by linking it with meteorological station data in a geographic information system (GIS) framework to investigate the spatial variation ...
1 In a previous study, we developed a model to predict the effects of temperature on performance of a fungus-based biopesticide for controlling locusts and grasshoppers. ...
Special thanks is extended to A. ...
doi:10.1111/j.1461-9563.2007.00336.x
fatcat:y2bh7k2h7jam7fsjnugex5lxfe
BN+1 Bayesian network expansion for identifying molecular pathway elements
2010
Communicative & Integrative Biology
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Biological interaction networks and pathways have been simulated and analyzed by various computational methods, for example, Bayesian networks, 1,2 mutual information, 3,4 neural network, 5,6 and centrality ...
A Bayesian network (BN) is a representation of a joint probability distribution over a set of random variables. 1 A BN includes two components: a directed acyclic graph (DAG) with vertices representing ...
It would also be ideal to incorporate experimental descriptions and curated information when identifying the biological bases for the underlying interactions inferred by the BN+1 algorithm. ...
doi:10.4161/cib.3.6.12845
pmid:21331236
pmcid:PMC3038060
fatcat:kubkjzmvszcyba27ghyomnhf2y
UV-Photoelectron Spectroscopy of BN Indoles: Experimental and Computational Electronic Structure Analysis
2014
Journal of the American Chemical Society
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Nucleus-independent chemical shifts calculations show that the introduction of boron into an aromatic 6π-electron system leads to a reduction in aromaticity, presumably due to a stronger bond localization ...
Thus, electronic structure consequences resulting from BN/CC isosterism will need to be evaluated individually from system to system. ...
Soc. 2014, 136, 11813−11820 ■ AUTHOR INFORMATION ...
doi:10.1021/ja5063899
pmid:25089659
pmcid:PMC4140474
fatcat:geooirid2bftfo4fz4voqn74cm
Purification and Characterization of the tRNA-processing Enzyme RNase BN
2000
Journal of Biological Chemistry
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RNase BN displays a number of unusual catalytic properties compared with the other exoribonucleases of E. coli. ...
RNase BN, a tRNA-processing enzyme previously shown to be required for the 3-maturation of certain bacteriophage T4-encoded tRNAs, was overexpressed and purified to near homogeneity from Escherichia coli ...
expression system (with changing of the medium to remove -lactamase and to restore ampicillin levels) resulted in a 25-fold overproduction of RNase BN during the 4-h induction period. ...
doi:10.1074/jbc.275.2.1030
pmid:10625642
fatcat:3n3juv7kjjcffhqfcgasecwfba
Thermodynamically Controlled, Dynamic Binding of Diols to a 1,2-BN Cyclohexane Derivative
2013
Organometallics
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The reversible covalent binding of diols to an N-Bn 1,2-BN cyclohexane has been studied by 11B and 1H NMR spectroscopy and single-crystal X-ray diffraction analysis. ...
Deuterium labeling experiments demonstrate that ligand exchange is reversible and rapid at room temperature, and competitive binding studies establish diol association as a thermodynamically controlled ...
The K eq data for systems 8−10 show that preorganization of the ligand into a cis geometry can improve the binding strength. ...
doi:10.1021/om400697r
pmid:25798022
pmcid:PMC4364440
fatcat:zmuu3rpxwfddvi5fv52tkpniaa
p-SCN-Bn-HOPO: A Superior Bifunctional Chelator for 89Zr ImmunoPET
2015
Bioconjugate chemistry
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We successfully synthesized p-SCN-Bn-HOPO, a bifunctional derivative of 3,4,3-(LI-1,2-HOPO) as a potential chelator for 89 Zr. ...
Recently, there has been a surge of interest in the development of an alternative chelator for 89 Zr 4+ to replace DFO, with several novel ligand systems being reported within the past year or so (Figure ...
a difference in biological applications. ...
doi:10.1021/acs.bioconjchem.5b00572
pmid:26550847
pmcid:PMC4962612
fatcat:prfuk5wdtvf6ja6hc3d67jq4fm
NeuroSuites-BNs: An open web framework for massive Bayesian networks focused on neuroscience
[article]
2020
bioRxiv
pre-print
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We present the capabilities of our proposed framework by highlighting a real example of a BN learned from genomic data obtained from Allen Institute for Brain Science. ...
NeuroSuites-BNs is the first web framework for learning, visualizing, and interpreting Bayesian networks (BNs) that can scale to tens of thousands of nodes while providing fast and friendly user experience ...
, and Fernando Rodriguez-820 Sanchez for his research in BN-based probabilistic clustering models and his help in reviewing that section in this paper. ...
doi:10.1101/2020.02.04.934174
fatcat:kt2jyyurdjcclogaohiv4hdeya
Scientific Opinion on the re-evaluation of Brilliant Black BN (E 151) as a food additive
2010
EFSA Journal
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In a recent study, Brilliant Black BN was found positive in a micronucleus test and a Comet assay in vitro. ...
The Panel on Food Additives and Nutrient Sources added to Food provides a scientific opinion re-evaluating the safety of Brilliant Black BN (E 151). ...
Information on existing authorisations and evaluations Brilliant Black BN is permitted as a food additive in the EU under Directive 94/36/EC. ...
doi:10.2903/j.efsa.2010.1540
fatcat:psettv4og5cq7bgbcs2nahckym
Rhodium-Catalyzed B–H Activation of 1,2-Azaborines: Synthesis and Characterization of BN Isosteres of Stilbenes
2014
Organic Letters
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Ten 1,2azaborine-based BN isosteres of stilbenes have been synthesized using this method, including a BN isostere of a biologically active stilbene. ...
It is demonstrated that BN/CC isosterism in the context of stilbenes can lead to significant changes in the observed photophysical properties such as higher quantum yield and a larger Stokes shift. ...
Ten examples of BN stilbenes have been synthesized using this method, including a BN isostere of a biologically active stilbene. ...
doi:10.1021/ol501362w
pmid:24916200
pmcid:PMC4068778
fatcat:fv4yewxjj5g47b5c22gje2ffri
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