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Eigenspectra optoacoustic tomography achieves quantitative blood oxygenation imaging deep in tissues

Stratis Tzoumas, Antonio Nunes, Ivan Olefir, Stefan Stangl, Panagiotis Symvoulidis, Sarah Glasl, Christine Bayer, Gabriele Multhoff, Vasilis Ntziachristos
2016 Nature Communications  
We discover a new principle underlying light fluence in tissues, which describes the wavelength dependence of light fluence as an affine function of a few reference base spectra, independently of the specific  ...  This finding enables the introduction of a previously undocumented concept termed eigenspectra Multispectral Optoacoustic Tomography (eMSOT) that can effectively account for wavelength dependent light  ...  The authors would like to thank Elena Nasonova and Karin Radrich for assisting in the blood phantom preparation and Amir Rosenthal and Juan Aguirre for the valuable discussions.  ... 
doi:10.1038/ncomms12121 pmid:27358000 pmcid:PMC4931322 fatcat:fx72ch7jzjbyjecinh2ebntpnu

2019 Index IEEE Transactions on Biomedical Engineering Vol. 66

2019 IEEE Transactions on Biomedical Engineering  
., +, TBME Jan. 2019 130-137 A Single Sensor Dual-Modality Photoacoustic Fusion Imaging for Compensation of Light Fluence Variation.  ...  ., +, TBME March 2019 802-809 A Single Sensor Dual-Modality Photoacoustic Fusion Imaging for Compensation of Light Fluence Variation.  ... 
doi:10.1109/tbme.2020.2964087 fatcat:mdfzsmdahnao5ccnuj232hycsm

Deep learning in photoacoustic imaging: a review

Handi Deng, Hui Qiao, Qionghai Dai, Cheng Ma
2021 Journal of Biomedical Optics  
For PA imaging (PAI), non-ideal signal detection deteriorates image quality, and quantitative PAI (QPAI) remains challenging due to the unknown light fluence spectra in deep tissue.  ...  Photoacoustic (PA) imaging can provide structural, functional, and molecular information for preclinical and clinical studies.  ...  The authors would like to thank Youwei Bao and Xiangxiu Zhang for assistance with figure copyright application.  ... 
doi:10.1117/1.jbo.26.4.040901 pmid:33837678 pmcid:PMC8033250 fatcat:uwutps2wfbfztfo6bvbv6g5f6y

Proceedings to the 2020 Online Conference of the Particle Therapy Cooperative Group (PTCOG2020Online)

2021 International Journal of Particle Therapy  
photoacoustic tomography.  ...  P 078 Precision for automatic segmentation of pelvic anatomies on CT images using deep neutral networks with multi-slices image inputs Purpose: To evaluate the precision for automatic segmentation of the  ...  application on a cyclotron-based BNCT system had started in Japan for head and neck cancer, and brain cancer.  ... 
doi:10.14338/ijpt.20-ptcog-7.4 pmid:33829075 pmcid:PMC8019577 fatcat:v2kbh3jnazck3jbyjk6fu6ckfi

A design methodology for 2D sparse NDE arrays using an efficient implementation of refracted-ray TFM

Jerzy Dziewierz, Timothy Lardner, Anthony Gachagan
2013 2013 IEEE International Ultrasonics Symposium (IUS)  
Recent advances in the field of tissue engineering include the engineering of skin, cartilage, and bladder, all of which are relatively thin tissues that can rely on diffusion for the delivery of oxygen  ...  venules) and one that more closely resembles capillaries.  ...  The authors acknowledge the ANR and DGA for their support under the project Metactif, grant ANR-11-ASTR-015.  ... 
doi:10.1109/ultsym.2013.0035 fatcat:th5znfh7y5bklfdbmhb4u6iq2i

Proceedings of the World Molecular Imaging Congress 2021, October 5-8, 2021: General Abstracts

2022 Molecular Imaging and Biology  
Conclusions: An efficient, iterative deconvolution algorithm with a novel resolution subsets-based approach that operates on patient DICOM images has been used for quantitative improvement in MRI clinical  ...  Materials and Methods: The method was tested on ACR MRI phantom and DICOM clinical MRI data. Data acquisition was performed on a commercial Siemens MRI system.  ...  We also thank Glenn Fulbright for isotope production and Katie Strychalski for technical support. and U01CA210170 . We thank Dr. Karen Horton for her support. AuNCs (Fig. 1b-c ).  ... 
doi:10.1007/s11307-021-01693-y pmid:34982365 pmcid:PMC8725635 fatcat:4sfb3isoyfdhfbiwxfr55gvqym

Proceedings of the World Molecular Imaging Congress 2020, October 7-9, 2020: General Abstracts

2022 Molecular Imaging and Biology  
Conclusion: Tumor specific uptake of pan800 provided remarkable contrast and a flexible imaging window for fluorescence-guided identification of HGGs despite modest EGFR expression.  ...  Target-to-background ratios maximized at 14 hours post pan800 infusion and reached 19.5 in vivo and 7.6 ex vivo, respectively.  ...  channel (Fig. 1f , and red arrows): microvascular sprouting (D3-D6, Fig. 1j,k ), anastomoses and flow establishment (D7-D9), and development of sinusoidal vessels (D7-D15).  ... 
doi:10.1007/s11307-021-01691-0 pmid:34982363 pmcid:PMC8725637 fatcat:ipn7hwekzzh6nbsk6dr2mzuhhm


2019 Zenodo  
In this work, an attempt was given to increase the specific effectiveness of chemovoltaic converter by changing the planar function of heterojunction on three-dimensional structure with high chemical activity  ...  S5 -Engineering and Industrial Physics The electricity consumption is also follows, using a digital power meter type UPT-210 (built by Algodue Elettronica, Italy).  ...  This information will be further used to implement concrete measures that will make the cooling system more efficient, ensuring both a better functioning of the computer systems and energy saving.  ... 
doi:10.5281/zenodo.2591122 fatcat:cgqeyphd4nbxrgthx36auadk7e

Report to the American Physical Society by the study group on research planning for coal utilization and synthetic fuel production

Bernard R. Cooper, Wayne R. Gruner, Larry Anderson, Robert H. Davis, Paul Engelking, Jose D. Garcia, Edward Gerjuoy, Robert I. Jaffee, Philip G. Kosky, Leonidas Petrakis, Robert T. Poe, Richard Pollina (+10 others)
1981 Reviews of Modern Physics  
The technical topics we have treated rather deal with monitoring and controlling such emissions. ) Such topics form research areas of their own and require considerations differing in generic as well as  ...  based his classification on observations using reflected 1 ight, while Thiessen based his on observations of thin sections by transmitted light.  ...  apt ur e g amma r ay t echn i que s for on-line analysi s of dense phase streams; imp r o v e d the rmocoup1 e sheaths; and laser -based combus t i on -mon i to r in g i n s trumentation, i nclud ing  ... 
doi:10.1103/revmodphys.53.s1 fatcat:3ver7ppwjfbv7mhbswvbeccqyu

Demonstration of chip-to-chip quantum teleportation

Y. Ding, D. Llewellyn, I. Faruque, S. Paesani, D. Bacco, R. Santagati, Y. Qian, Y. Li, Y. Xiao, M. Huber, M. Malik, G. Sinclair (+8 others)
2019 Conference on Lasers and Electro-Optics   unpublished
We engineer quasi 3D structured light fields in which the orbital angular momentum changes locally in both sign and magnitude along the beam's axis and explain how such transitions occur without violating  ...  ., USA Natalia Litchinitser, Univ. at Electrical and Computer Engineering, Univ. of Toronto, Canada; 2 School of Physics, Univ. of the Witwatersrand, South Africa.  ...  and broadband light sources for optical coherence tomography M.  ... 
doi:10.1364/cleo_at.2019.jth5c.4 fatcat:ytixbvycv5e7tlcr5m74negtlu