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Front Matter: Volume 10140
2017
Medical Imaging 2017: Digital Pathology
Preserved Fulltext
Publication of record for individual papers is online in the SPIE Digital Library. SPIEDigitalLibrary.org Paper Numbering: Proceedings of SPIE follow an e-First publication model. ...
Utilization of CIDs allows articles to be fully citable as soon as they are published online, and connects the same identifier to all online and print versions of the publication. ...
(USA) Automated epidermis segmentation in histopathological images of human skin stained with hematoxylin and eosin 10140 0NAutomated cancer stem cell recognition in H and E stained tissue using convolutional ...
doi:10.1117/12.2270372
dblp:conf/midp/X17
fatcat:6yeb63ix6bau7jhipthayjih24
Automated segmentation of skin strata in reflectance confocal microscopy depth stacks
[article]
2015
bioRxiv
pre-print
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However, current use of RCM depends on qualitative examination by a human expert to look for specific features in the different strata of the skin. ...
The probabilities predicted by the classifier in the test set showed that the classifier learned an effective model of the anatomy of human skin. ...
by hematoxylin and eosin staining only a monochrome image showing variation in reflectance at one wavelength is available. ...
doi:10.1101/022137
fatcat:uq6ivoiofzbvtn4tfkf6jgfiiu
Automated Segmentation of Skin Strata in Reflectance Confocal Microscopy Depth Stacks
2016
PLoS ONE
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However, current use of RCM depends on qualitative examination by a human expert to look for specific features in the different strata of the skin. ...
The probabilities predicted by the classifier in the test set showed that the classifier learned an effective model of the anatomy of human skin. ...
by hematoxylin and eosin staining only a monochrome image showing variation in reflectance at one wavelength is available. ...
doi:10.1371/journal.pone.0153208
pmid:27088865
pmcid:PMC4835045
fatcat:yq6sdfl2ave7phy7tbjbh3skpi
A Texture Based Pattern Recognition Approach to Distinguish Melanoma from Non-Melanoma Cells in Histopathological Tissue Microarray Sections
2013
PLoS ONE
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Images representing immunostained melanoma tissue were then digitally processed to segment regions of interest, highlighting Melan-A positive and negative areas. ...
Tedious manual assessment of immunohistochemically stained tissue needs to be fully automated to take full advantage of the potential for high throughput analyses enabled by tissue microarrays and digital ...
Carolina Whä lby at Center for Image analysis, Uppsala University for the fruitful discussions on the data analysis and experimental design.
Author Contributions ...
doi:10.1371/journal.pone.0062070
pmid:23690928
pmcid:PMC3656869
fatcat:dznfhjq6bbap3e5lzpddex7xxm
Electrochemical treatment of ex vivo human abdominal skin and potential use in scar management: A pilot study
2021
Scars, Burns & Healing
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The width of dye color change for each dosimetry pair was calculated. Hematoxylin and eosin staining was used to evaluate samples. ...
The purpose of this study is to examine the acid-base and histological changes in ex vivo human abdominal skin following ECT. ...
Funding The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: ...
doi:10.1177/2059513120988532
pmid:33796338
pmcid:PMC7970177
fatcat:d63xptdodjastbxjhv2ogxkgti
Performance of a simple chromatin-rich segmentation algorithm in quantifying basal cell carcinoma from histology images
2012
BMC Research Notes
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Findings: Haematoxylin and eosin stained basal cell carcinoma histology slides were digitized and analyzed using the open source image analysis program ImageJ. ...
The use of digital imaging and algorithm-assisted identification of regions of interest is revolutionizing the practice of anatomic pathology. ...
and eosin stain components using the built-in H&E vector. ...
doi:10.1186/1756-0500-5-35
pmid:22251818
pmcid:PMC3398325
fatcat:4aitwbhj65c6vl7xkmp3hocbte
Inhibition of DNA damage response at telomeres improves the detrimental phenotypes of Hutchinson–Gilford Progeria Syndrome
2019
Nature Communications
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We also show in vivo that tASO treatment significantly enhances skin homeostasis and lifespan in a transgenic HGPS mouse model. ...
In summary, our results demonstrate an important role for telomeric DDR activation in HGPS progeroid detrimental phenotypes in vitro and in vivo. ...
Data availability The authors state that all data generated during this study are included in the article, its supplementary information file, and the Source Data file, and are available from the corresponding ...
doi:10.1038/s41467-019-13018-3
pmid:31740672
pmcid:PMC6861280
fatcat:4zqzzzwtxff33h3rzsjdg3lhlq
A New Approach to Border Irregularity Assessment with Application in Skin Pathology
2019
Applied Sciences
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The proposed segmentation method has been tested on 25. skin whole slide images of common melanocytic lesions. ...
Our method is particularly well suited for assessing the border irregularity of human epidermis and thus could help develop computer-aided diagnostic algorithms for skin cancer detection. ...
Conflicts of Interest: The authors declare no conflict of interest. ...
doi:10.3390/app9102022
fatcat:7usgtjvgr5csbdm4unzj6jjkuu
Fully Convolutional Network for Melanoma Diagnostics
[article]
2018
arXiv
pre-print
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Given the qualitative and quantitative results, it is possible to overcome the discriminative challenges of the skin and tumour anatomy for segmentation using modern machine learning techniques, though ...
We provide gold standard annotations for three tissue types (tumour, epidermis, and dermis) which are important for the prognostic measurements known as Breslow thickness and Clark level. ...
The gold standard for the diagnosis of melanoma requires full-thickness excisional biopsy of suspected lesions followed by the histopathologic analysis of hematoxylin and eosin (H&E) stained tissue sections ...
arXiv:1806.04765v1
fatcat:ssps2yurbzhzvj2kgkbrutfmdu
Semiquantitative histopathology and 3D magnetic resonance microscopy as collaborative platforms for tissue identification and comparison within teratomas derived from pedigreed primate embryonic stem cells
2010
Stem Cell Research
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Teratomas were subsequently serially sectioned and tissue types identified, semiquantitated, and correlated with MRM images. ...
MRM provides rapid quantitative imaging of intact teratomas that complements histology and identifies sites of interest for additional biological studies. ...
of Pittsburgh for providing the tissue sections and immunohistochemistry presented in this paper. ...
doi:10.1016/j.scr.2010.07.005
pmid:20864427
pmcid:PMC2975385
fatcat:5mou6fsb4jalzn7swchbu3yyzu
Automatic detection of melanoma progression by histological analysis of secondary sites
2012
Cytometry Part A
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We present results from machine classification of melanoma biopsies sectioned and stained with hematoxylin/eosin (H&E) on tissue micro-arrays (TMA). ...
In our experiments we constructed an HE color space by digitally deconvolving the RGB images into separate H (hematoxylin) and E (eosin) channels. ...
Acknowledgments This research was supported by the Intramural Research Program of the NIH, National Institute on Aging (Z01: AG000685-02).
Literature Cited ...
doi:10.1002/cyto.a.22044
pmid:22467531
pmcid:PMC3331954
fatcat:443mj6zu7nfylgnw4jivk3eefe
The Effect of Projection Microstereolithographic Fabricated Implant Geometry on Myocutaneous Revascularization
2014
Surgical Science
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Laser speckle contrast imaging demonstrated flap revascularization in (SP) mice, and markedly reduced distal flap reperfusion in (S) mice. ...
Clark et al. communication between recipient bed and flap with lack of bridging inflammatory cells and neovasculature and resultant distal tissue necrosis. ...
Note the regenerating epidermis and viable panniculus carnosus muscle (Hematoxylin and eosin stain, 100× magnification); (B) Hematoxylin and eosin stain (100× magnification) of corresponding region of ...
doi:10.4236/ss.2014.512079
fatcat:4lrle2pycjfepfzfd2gbquhrsa
The Effect of Projection Microstereolithographic Fabricated Implant Geometry on Myocutaneous Revascularization
2014
Journal of Surgical Research
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Laser speckle contrast imaging demonstrated flap revascularization in (SP) mice, and markedly reduced distal flap reperfusion in (S) mice. ...
Clark et al. communication between recipient bed and flap with lack of bridging inflammatory cells and neovasculature and resultant distal tissue necrosis. ...
Note the regenerating epidermis and viable panniculus carnosus muscle (Hematoxylin and eosin stain, 100× magnification); (B) Hematoxylin and eosin stain (100× magnification) of corresponding region of ...
doi:10.1016/j.jss.2013.11.716
fatcat:ugo2avthabakxl4nfzen4ve6ra
Classification of basal cell carcinoma in human skin using machine learning and quantitative features captured by polarization sensitive optical coherence tomography
2016
Biomedical Optics Express
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We report the first fully automated detection of basal cell carcinoma (BCC), the most commonly occurring type of skin cancer, in human skin using polarization-sensitive optical coherence tomography (PS-OCT ...
Our classifier achieved 95.4% sensitivity and specificity, validated by leave-one-patient-out cross validation (LOPOCV), in detecting BCC in human skin samples collected from 42 patients. ...
Acknowledgments We would like to thank Owen Ma, Jamaica Jensen, Samantha Rodriguez, and Katherine Ransohoff of the Stanford dermatology clinic for their help in collecting human samples. ...
doi:10.1364/boe.7.003721
pmid:27699133
pmcid:PMC5030045
fatcat:takyff6msvf5nmowdqe6lpqdta
Optimization of multimodal spectral imaging for assessment of resection margins during Mohs micrographic surgery for basal cell carcinoma
2014
Biomedical Optics Express
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sample preparation and subjective interpretation of stained frozen-sections. ...
In this study, the MSI algorithm was optimized to maximize the diagnosis accuracy while minimizing the number of Raman spectra: the segmentation of the auto-fluorescence images was optimized according ...
The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health. ...
doi:10.1364/boe.6.000098
pmid:25657878
pmcid:PMC4317116
fatcat:od7bjkjmara73nlpnhtaqzyu4y
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