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Automatic Detection and Classification of Malarial Retinopathy- Associated Retinal Whitening in Digital Retinal Images

Muhammad Usman Akram, Abu Bakar Nisar Alvi, Shoab Ahmed Khan
2017 Mehran University Research Journal of Engineering and Technology  
Malarial retinopathy addresses diseases that are characterized by abnormalities in retinal fundus imaging.  ...  The paper proposes a computerized detection and classification method for malarial retinopathy using retinal whitening as a bio-marker.  ...  of Malarial Retinopathy-Associated Retinal Whitening in Digital Retinal Images FIG. 6.  ... 
doi:10.22581/muet1982.1704.19 fatcat:yu62thfn4zhb7n5dr73uw725x4

Automated Detection of Malarial Retinopathy in Digital Fundus Images for Improved Diagnosis in Malawian Children with Clinically Defined Cerebral Malaria

Vinayak Joshi, Carla Agurto, Simon Barriga, Sheila Nemeth, Peter Soliz, Ian J. MacCormick, Susan Lewallen, Terrie E. Taylor, Simon P. Harding
2017 Scientific Reports  
This automated system for detecting MR using retinal color images has the potential to improve the accuracy of CM diagnosis.  ...  This yielded sensitivity/specificity of 95%/100% for the detection of MR overall, and 65%/94% for retinal whitening, 62%/100% for vessel discoloration, and 73%/96% for hemorrhages.  ...  The retinal image dataset was provided by the Department of Eye and Vision Science at the University of Liverpool.  ... 
doi:10.1038/srep42703 pmid:28198460 pmcid:PMC5309896 fatcat:gsok7g3z7vhgvfajmzihz34a2u

Automated Detection of Malarial Retinopathy-Associated Retinal Hemorrhages

Vinayak S. Joshi, Richard J. Maude, Joseph M. Reinhardt, Li Tang, Mona K. Garvin, Abdullah Abu Sayeed, Aniruddha Ghose, Mahtab Uddin Hassan, Michael D. Abràmoff
2012 Investigative Ophthalmology and Visual Science  
To develop an automated method for the detection of retinal hemorrhages on color fundus images to characterize malarial retinopathy, which may help in the assessment of patients with cerebral malaria.  ...  The method provides an automated means of detecting retinal hemorrhages associated with malarial retinopathy. The results matched well with the reference standard.  ...  toward the detection of diabetic retinopathy and AMD retinal phenotypes.  ... 
doi:10.1167/iovs.12-10191 pmid:22915035 pmcid:PMC3460387 fatcat:zh2hzxsp2bcu3c3wcvtw44ggy4

Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina

Valentina Barrera, Ian James Callum MacCormick, Gabriela Czanner, Paul Stephenson Hiscott, Valerie Ann White, Alister Gordon Craig, Nicholas Alexander Venton Beare, Lucy Hazel Culshaw, Yalin Zheng, Simon Charles Biddolph, Danny Arnold Milner, Steve Kamiza (+3 others)
2018 eLife  
Retinal vessel changes and retinal whitening, distinctive features of malarial retinopathy, can be directly observed during routine eye examination in children with P. falciparum cerebral malaria.  ...  in blood-retinal barrier cells and marked loss/disruption of pericytes.  ...  retinal zones in grading of malarial retinopathy 770 Supplementary file 1 Comparison of children without and with admission retinal exam data 771 Retinal whitening was graded separately from the MR grade  ... 
doi:10.7554/elife.32208 pmid:29578406 pmcid:PMC5898913 fatcat:3ic4vrjodfewfhnxdzhpa2mftm

Automated Detection of Leakage in Fluorescein Angiography Images with Application to Malarial Retinopathy

Yitian Zhao, Ian J. C. MacCormick, David G. Parry, Sophie Leach, Nicholas A. V. Beare, Simon P. Harding, Yalin Zheng
2015 Scientific Reports  
The detection and assessment of leakage in retinal fluorescein angiogram images is important for the management of a wide range of retinal diseases.  ...  We have developed a framework that can automatically detect three types of leakage (large focal, punctate focal, and vessel segment leakage) and validated it on images from patients with malarial retinopathy  ...  The support of these groups was essential for the success of this work.  ... 
doi:10.1038/srep10425 pmid:26030010 pmcid:PMC4450752 fatcat:tnnpfu2ubjdcrottzqj2dy237y

Haemorrhage Detection and Classification: A Review

Priyanka Jaware
2017 International Journal of Engineering Research and Applications  
The effect due to DR can reduce by early detection of Haemorrhages and treated at an early stage. In recent year, there is an increased interest in the field of medical image processing.  ...  The most common symptom of the person with diabetes is diabetic retinopathy, which leads to blindness.  ...  Asra Ashraf et al. [21] Retinal Whitening Own database from AFIO Hospital Rawalpindi discriminating features SVM It is a novel method for automated diagnosis of malarial retinopathy  ... 
doi:10.9790/9622-0702045258 fatcat:qt5cxmpttjbd5gknuxtayrtjzq

Detection and Classification of Cotton Wool Spots in Diabetic Retinopathy

2019 International journal of recent technology and engineering  
Further increase of blood glucose lead to serious complications and it will affect major organs of our body. Diabetes affects both of the eyes called Diabetic Retinopathy (DR).  ...  The main objective of this paper is to detect Cotton Wool Spots (CWS) using morphological operations and the spots are segmented using k-means segmentation.  ...  Decision tree classifier is used to classify all early stage lesions in diabetic retinopathy. Malarial Retinopathy [8] affects retina of the eye.  ... 
doi:10.35940/ijrte.c6805.098319 fatcat:l6uqmbkhq5aoxjiatyx4l46tii

Grading fluorescein angiograms in malarial retinopathy

Ian J. C. MacCormick, Richard J. Maude, Nicholas A. V. Beare, Shyamanga Borooah, Simon Glover, David Parry, Sophie Leach, Malcolm E. Molyneux, Baljean Dhillon, Susan Lewallen, Simon P. Harding
2015 Malaria Journal  
Conclusions: This grading scheme provides a consistent way to describe retinal vascular damage in paediatric cerebral malaria, and can facilitate comparisons of angiographic features of malarial retinopathy  ...  Methods: A grading scheme for fluorescein angiographic images was devised based on consensus opinion of clinicians and researchers experienced in malarial retinopathy in children and adults.  ...  Malarial retinopathy was diagnosed by an ophthalmologist on the basis of bilateral dilated indirect ophthalmoscopy and defined as any one of retinal haemorrhage, retinal whitening, or orange or white retinal  ... 
doi:10.1186/s12936-015-0897-7 pmid:26403288 pmcid:PMC4583163 fatcat:6hsfz4q65jdstniz76jh2nzlbq

Front Matter: Volume 9785

2016 Medical Imaging 2016: Computer-Aided Diagnosis  
Publication of record for individual papers is online in the SPIE Digital Library. SPIEDigitalLibrary.org Paper Numbering: Proceedings of SPIE follow an e-First publication model.  ...  of SPIE Vol. 9785 978501-3 Downloaded From: https://www.spiedigitallibrary.org/conference-proceedings-of-spie on 7/22/2018 Terms of Use: https://www.spiedigitallibrary.org/terms-of-use iv Proc. of SPIE  ...  85] 9785 2F Automated blood vessel extraction using local features on retinal images [9785-86] 9785 2G Automated detection of retinal whitening in malarial retinopathy [9785-87] 9785 2H Finding  ... 
doi:10.1117/12.2240961 dblp:conf/micad/X16 fatcat:b5addnksdrgp3ixwvbjt53xeqe

Retinal Glaucoma Detection Using Deep Learning Algorithm

Tanya Maurya, Lalitha Kala, Kaveti Manasa, Kanimozhi Gunasekaran
2022 International Journal of Intelligent Systems and Applications in Engineering  
A novel method of analyzing retinal images by detecting vessels and exudates has been proposed to analyze retinal vascular disorders.  ...  In this work, a minimum of 10 features such as Mean, Variance, Entropy with the data set trained images on 15 images using NN (neural network) training is implemented, and NN classifier based Normal or  ...  Figures showing two different retinal diseases with focal leakages. (a) malarial retinopathy (b) glaucomatic retinopathy. Fig. 2 . 2 Fig. 2.  ... 
doi:10.18201/ijisae.2022.267 fatcat:vfhetews45a6ln3x3y2r6ewf7e

Dengue-associated Eye Disease

Neethu Latif, Kowsigan Mageshan, Jyotirmay Biswas, Parthopratim Dutta Majumder
2019 Nepalese Journal of Ophthalmology  
(Su et al. 2007) Table 1 : 1 Diff erential diagnosis of dengue associated eye disease Diff erential diagnosis of dengue associated eye disease Malaria Malarial retinopathy characterized by retinal whitening  ...  useful in detecting previous infection.  ... 
doi:10.3126/nepjoph.v11i2.27814 pmid:32792686 fatcat:qvlqhzclwjebjbppnhqap2epiq

Pathogenesis of cerebral malaria: new diagnostic tools, biomarkers, and therapeutic approaches

Praveen K. Sahu, Sanghamitra Satpathi, Prativa K. Behera, Saroj K. Mishra, Sanjib Mohanty, Samuel Crocodile Wassmer
2015 Frontiers in Cellular and Infection Microbiology  
While the complete landscape of the pathogenesis of cerebral malaria still remains to be elucidated, numerous innovative approaches have been developed in recent years in order to improve the early detection  ...  In this review, we briefly summarize the current understanding of cerebral malaria pathogenesis, compile the array of new biomarkers and tools available for diagnosis and research, and describe the emerging  ...  His contributions to tropical medicine, and to the management of cerebral malaria in particular, saved the lives of many. He will be sorely missed.  ... 
doi:10.3389/fcimb.2015.00075 pmid:26579500 pmcid:PMC4621481 fatcat:e3uxblkym5cmxk45k7gq6ah6qu

Neuro-Ophthalmic Literature Review

Panitha Jindahra, Axel Petzold, Evan Price, John H. Pula, Michael Vaphiades, Sui Wong
2015 Neuro-ophthalmology (Aeolus Press. 1980)  
To determine whether malarial retinopathy reflects cerebrovascular injury, the authors reviewed retinal and cerebral manifestations of malaria in children.  ...  MALARIAL RETINOPATHY MacCormick IJC, Beare NAV, Taylor TE, Barrera V, White VA, Hiscott P, Molyneux ME, Dhillon B, Harding SP. Cerebral malaria in children: using the retina to study the brain.  ...  Despite extensive work-up, no other aetiology for the optic neuropathies were detected.  ... 
doi:10.3109/01658107.2015.999505 pmcid:PMC5123147 fatcat:enzqsqolajg4le47nthilw7eme

Endoglin in African Children withPlasmodium falciparumMalaria: A Novel Player in Severe Malaria Pathogenesis?

Anelia Dietmann, Raimund Helbok, Peter Lackner, Marlene Fischer, Markus Reindl, Bertrand Lell, Saadou Issifou, Peter G. Kremsner, Erich Schmutzhard
2009 Journal of Infectious Diseases  
was found in 85.7% of patients with cerebral malaria and 46.5% of patients with severe malaria.  ...  The soluble form of the auxiliary receptor endoglin (sEng) may play a role in malaria pathogenesis. Methods.  ...  It is tempting to speculate that TGF-b inhibition via high sEng levels could play a role in malarial retinopathy, influencing development of retinal whitening, vessel changes, retinal hemorrhages, and  ... 
doi:10.1086/648476 pmid:19919302 fatcat:3hy75bl6lzg4ne6v7ig6gyy3he

Sequestration of infected red blood cells and reduced venous efflux precede excessive inflammatory responses in experimental cerebral malaria [article]

Rituparna Bhattacharjee, Universitäts- Und Landesbibliothek Sachsen-Anhalt, Martin-Luther Universität, Eike Budinger
2022
Simultaneously, a pro-inflammatory storm of cytokines and chemokines could be detected at this late phase of ECM.  ...  In comparison, activation of astrocytes, microglia, endothelial cells and accumulation of leukocytes like CD8+ T cells were observed mostly at a later stage in the neurologically sick mice.  ...  Retinopathy can be observed in both children and adults affected with CM and can be characterised by four features: retinal whitening, vessel changes, retinal haemorrhages and papilledema.  ... 
doi:10.25673/79565 fatcat:4vxzxvadxzdv5hbd5f4gqvbzsm
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