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Automated detection of brain atrophy patterns based on MRI for the prediction of Alzheimer's disease
2010
NeuroImage
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pattern matching for the prediction of the conversion from MCI to AD. ...
Voxel-based MRI studies have demonstrated that widely distributed cortical and subcortical brain areas show atrophic changes in MCI, preceding the onset of AD-type dementia. ...
Foundation Ireland (SFI) as part of the SFI Stokes Programme (to ALWB), a grant from the Hirnliga Foundation, Germany (to SJT), a grant from the German Center on Neurodegenerative Disorders (DZNE) within ...
doi:10.1016/j.neuroimage.2009.11.046
pmid:19961938
pmcid:PMC2838472
fatcat:w33gytmvjrhhzkgkot4prph6um
A list of publications describing new supervised learning pipelines to predict clinical variables from neuroimaging data in Alzheimer's disease
2016
Figshare
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This is a list of publications describing new classification and regression methods to predict clinical variables relevant to Alzheimer's disease using neurological images. ...
It is intended as a companion document for my thesis. ...
An intelligent technique for detecting Alzheimer's disease based on brain structural changes and hippocampal shape. ...
doi:10.6084/m9.figshare.3435752
fatcat:mdtfbkinjzfezcg6qhhwx43s4e
Quantitative structural MRI for early detection of Alzheimer's disease
2010
Expert Review of Neurotherapeutics
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Objective evidence of ongoing brain atrophy will be critical for risk/benefit decisions once potentially aggressive, disease-modifying treatments become available. ...
Recent advances have paved the way for the use of quantitative structural MRI in clinical practice, and initial clinical use has been promising. ...
The advent of computer-based methods for quantitative MRI has allowed for efficient quantification of AD-related atrophy across the brain [51] [52] [53] [54] [55] . ...
doi:10.1586/ern.10.162
pmid:20977326
pmcid:PMC3182103
fatcat:7uqcwd77cfdgnhdpsvuxcg64vu
Tracking Alzheimer's Disease
2007
Annals of the New York Academy of Sciences
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We report the first time-lapse maps of cortical atrophy spreading dynamically in the living brain, based on averaging data from populations of subjects with Alzheimer's disease and normal subjects imaged ...
drug trials, and shed light on the neuroscience of brain degeneration in Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI). ...
This research was supported by the National Institute on Aging, the National Library of Medicine, the National Institute for Biomedical Imaging and Bioengineering, the National Center for Research Resources ...
doi:10.1196/annals.1379.017
pmid:17413023
pmcid:PMC3197831
fatcat:ztx5gpereze5fiujthiwuktr5q
Alliance for Aging Research AD Biomarkers Work Group: structural MRI
2011
Neurobiology of Aging
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In addition, AD biomarkers are an essential component of recently updated diagnostic criteria for AD from the National Institute on Aging -Alzheimer's Association. ...
This article reviews evidence supporting the position that MRI is a biomarker of neurodegenerative atrophy. ...
Acknowledgments The Alexander Family Alzheimer's Disease Research Professorship of the Mayo Foundation, USA, and the Robert H. and Clarice Smith Alzheimer's Disease Research Program of the Mayo Foundation ...
doi:10.1016/j.neurobiolaging.2011.09.011
pmid:22078173
pmcid:PMC3661287
fatcat:kyu6vx6a6rezlb4j6laq5emgte
Efficient Morphometric Techniques in Alzheimer's Disease Detection: Survey and Tools
2016
Neuroscience International
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The development of advance techniques in the multiple fields such as image processing, data mining and machine learning are required for the early detection of Alzheimer's Disease (AD) and to prevent the ...
progression of the disease to the later stages. ...
The corresponding author confirms that all of the other authors have read and approved the manuscript and there are no ethical issues involved. ...
doi:10.3844/amjnsp.2016.19.44
fatcat:3zeb2s5pjzfv7mptqi7cy2a3au
Role of structural MRI in Alzheimer's disease
2010
Alzheimer's Research & Therapy
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and intensity of the neurodegenerative aspect of Alzheimer's disease (AD) pathology. ...
Alzheimer's disease (AD) is a multifaceted disease in which cumulative pathological brain insults result in progressive cognitive decline that ultimately leads to dementia. ...
One of the most sensitive global measures for measuring the rates of brain atrophy is the ventricular change measure using BSI [24] . ...
doi:10.1186/alzrt47
pmid:20807454
pmcid:PMC2949589
fatcat:ua2c6ky2prdzpp42kxq4rlmp2q
Science to Practice: Translating Automated Brain MRI Volumetry in Alzheimer's Disease from Research to Routine Diagnostic Use in the Work-Up of Dementia
2014
Frontiers in Neurology
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Atrophy of the MTL is particularly important because it can be detected earlier than generalized whole brain atrophy in AD. ...
Impairment of declarative memory is one of the earliest symptoms of Alzheimer's disease (AD), the most common form of dementia. ...
doi:10.3389/fneur.2013.00216
pmid:24409168
pmcid:PMC3885875
fatcat:tdmq6exjrjgnxavzmtzmactc4u
An Overview of Quantitative Magnetic Resonance Imaging Analysis Studies in the Assessment of Alzheimer's Disease
[chapter]
2016
International Federation for Medical and Biological Engineering Proceedings
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CONFLICT OF INTEREST "The authors declare that they have no conflict of interest ...
help on the detection of neuronal loss in the initial stages of the disease. ...
The challenge for modern neuroimaging is to help in the early diagnosis of Alzheimer's disease and structural MRI is one of the biomarkers that could be selected in the assessment of early AD. ...
doi:10.1007/978-3-319-32703-7_56
fatcat:ryyepcaberbxhhxgjutojtnae4
Proceeding and abstracts,second meeting of the Alzheimer's imaging consortium,Stockholm,Fairgrounds,Stockholm,Sweden,July20,2002
2004
Neurobiology of Aging
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detecting the presence of Alzheimer's disease. ...
Order of the scans was randomized, correction for persisting activity of the first scan was performed. Atrophy correction was done in the activation group PET scans based on individual MRI. ...
Background: Previous investigators have measured longitudinal change of brain structure in Alzheimer's disease (AD) and normal aging using different methods, on different populations. ...
doi:10.1016/s0197-4580(03)00003-4
fatcat:ceywsycy2vappownkwlltj5lxi
Anatomically Standardized Detection of MRI Atrophy Patterns in Early-Stage Alzheimer's Disease
2021
Brain Sciences
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MRI studies have consistently identified atrophy patterns in Alzheimer's disease (AD) through a whole-brain voxel-based analysis, but efforts to investigate morphometric profiles using anatomically standardized ...
These morphologically distinct subtypes are based on standardized brain regions, which are anatomically defined and freely accessible so as to validate its diagnostic accuracy and enhance the prediction ...
MRI data. ...
doi:10.3390/brainsci11111491
pmid:34827490
pmcid:PMC8615991
fatcat:ojmjkcjrvrgl3iu3ljy32lew7q
Automated identification of dementia using medical imaging: a survey from a pattern classification perspective
2015
Brain Informatics
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Since most of those algorithms consist of both feature extraction and classification, we provide a survey on three categories of feature extraction methods, including the voxel-, vertex-and ROI-based ones ...
In this review paper, we summarized the automated dementia identification algorithms in the literature from a pattern classification perspective. ...
Recently, Liu et al. proposed a simulation method to predict the longitudinal brain morphological changes in neurodegenerative brains based on VBM [52] . ...
doi:10.1007/s40708-015-0027-x
pmid:27747596
pmcid:PMC4883162
fatcat:yefc226j4za75afkkkolg4m5n4
Prediction of Amyloid Positivity in Mild Cognitive Impairment Using Fully Automated Brain Segmentation Software
2020
Neuropsychiatric Disease and Treatment
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of KoreaTel +82-2-2072-2205Fax +82-2-744-7241Email selfpsy@snu.ac.krObjective: To assess the predictive ability of regional volume information provided by fully automated brain segmentation software for ...
cerebral amyloid positivity in mild cognitive impairment (MCI).Methods: This study included 130 subjects with amnestic MCI who participated in the Korean brain aging study of early diagnosis and prediction ...
Materials and Methods Participants This study is based on the Korean Brain Aging Study for Early Diagnosis and Prediction of Alzheimer’s Disease (KBASE), 20 an ongoing, prospective, community-based cohort ...
doaj:73031b65eb5345b5867a838aad1f99d7
fatcat:tsre6su4rvggretb4ikpok6bi4
Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2
2015
Alzheimer's & Dementia
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The primary objective of the magnetic resonance imaging (MRI) core of ADNI has been to improve methods for clinical trials in Alzheimer's disease (AD) and related disorders. ...
metrics; deriving sample size estimates for future trials based on those outcomes; and ...
Introduction The overarching objective for the Alzheimer's Disease Neuroimaging Initiative (ADNI) magnetic resonance imaging (MRI) core has been to improve methods for clinical trials in Alzheimer's disease ...
doi:10.1016/j.jalz.2015.05.002
pmid:26194310
pmcid:PMC4523217
fatcat:xf473xlapvgbvekh4oxvkyk5wy
Biomarkers for Early Detection of Alzheimer Pathology
2007
Neurosignals
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Strategies to accomplish this include the detection of altered levels of tau and amyloid in cerebrospinal fluid, the use of structural MRI to identify disease-specific patterns of regional atrophy and ...
Success will facilitate the ability to reliably diagnose Alzheimer's disease while the symptoms of brain failure are mild and may provide objective measures of disease-modifying treatment efficacy. ...
Support for research summarized here comes from the NIH (AG10124), the Pennsylvania Department of Health (SAP4100027296), the James Previti Family Fund and Marian S. Ware. ...
doi:10.1159/000109754
pmid:18097155
pmcid:PMC2866153
fatcat:t7wofsgo6vc4fnnaque2cpdj2i
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