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Automatizing a nonscripting TPS for optimizing clinical workflow and reoptimizing IMRT/VMAT plans

Rafael Ayala, Gema Ruiz, Teresa Valdivielso
2019 Medical Dosimetry  
The software that we used was based on an open-source library that mimics human interaction with Microsoft Windows applications.  ...  The impact of this tool on clinical workflow is important, as it not only provides better efficiency, but also increases treatment quality.  ...  It is then relatively easy to analyze calculated plans and also to adjust cost functions with an external tool.  ... 
doi:10.1016/j.meddos.2019.02.006 pmid:30952384 fatcat:z4zlidoitjbkrfc5z4nrk4ktlu

Smart Meter Data Analytics

Xiufeng Liu, Lukasz Golab, Wojciech Golab, Ihab F. Ilyas, Shichao Jin
2016 ACM Transactions on Database Systems  
As this regard, the paper focuses on building an innovative software solution to streamline smart meter data analytic, aiming at dealing with the complexity of data processing and data analytics.  ...  The system offers an information integration pipeline to ingest smart meter data; scalable data processing and analytic platform for pre-processing and mining big smart meter data sets; and a web-based  ...  Hive is an SQL-to-MapReduce translator with an SQL dialect, HiveQL, for querying data stored in Fig. 3 . The building blocks of data processing layer a cluster.  ... 
doi:10.1145/3004295 fatcat:hsodh2jiire5fkh4rklc6b6hwe

A hybrid ICT-solution for smart meter data analytics

Xiufeng Liu, Per Sieverts Nielsen
2016 Energy  
This paper proposes an innovative ICT-solution to streamline smart meter data analytics.  ...  The proposed solution offers an information integration pipeline for ingesting data from smart meters, a scalable platform for processing and mining big data sets, and a web portal for visualizing analytics  ...  It is also easy to extend the analytic layer by adding new algorithms.  ... 
doi:10.1016/j.energy.2016.05.068 fatcat:vgsr5f4umrcojkvso7jdifttr4

Decoding Neuromuscular Disorders Using Phenotypic Clusters Obtained From Co-Occurrence Networks

Elena Díaz-Santiago, M. Gonzalo Claros, Raquel Yahyaoui, Yolanda de Diego-Otero, Rocío Calvo, Janet Hoenicka, Francesc Palau, Juan A. G. Ranea, James R. Perkins
2021 Frontiers in Molecular Biosciences  
This work is an example of reproducible research that i) can help better understand NMDs and support their diagnosis by providing a new tool that exploits existing information to obtain novel clusters  ...  In parallel, a tripartite network based on phenotypes, diseases and genes was used to associate NMD phenotypes with functions, an approach also validated by literature co-mention, with KEGG pathways showing  ...  The workflow was managed using AutoFlow (Seoane et al., 2016) . For co-occurrence analysis, PhenoClusters requires NetAnalyzer (Rojano et al., 2017) .  ... 
doi:10.3389/fmolb.2021.635074 pmid:34046427 pmcid:PMC8147726 fatcat:laafcaukefgfrakdxw4q5rmo64

Evaluating, Filtering and Clustering Genetic Disease Cohorts Based on Human Phenotype Ontology Data with Cohort Analyzer

Elena Rojano, José Córdoba-Caballero, Fernando M. Jabato, Diana Gallego, Mercedes Serrano, Belén Pérez, Álvaro Parés-Aguilar, James R. Perkins, Juan A. G. Ranea, Pedro Seoane-Zonjic
2021 Journal of Personalized Medicine  
The tool itself is freely available alongside a workflow to allow the analyses shown in this work to be applied to other datasets.  ...  For two of the cohorts, we also analysed genomic data related to the patients, and linked the genomic data to the patient-subgroups by mapping shared variants to genes and functions.  ...  This workflow uses the manager AutoFlow and can be run on UNIX-like systems. All dependencies are explained in the README file of the GitHub repository.  ... 
doi:10.3390/jpm11080730 pmid:34442375 pmcid:PMC8398478 fatcat:a4psvjd3d5dvnaoaegpycinuoe

SCHEDULING AND FLEXIBLE CONTROL OF WIDE-AREA DATA TRANSPORT SERVICES FOR END-TO-END APPLICATION WORKFLOWS Scheduling and Flexible Control of Wide-Area Data Transport Services for End-to-End Application Workflows

Mehmet Aktas, Mehmet Aktas
2015 unpublished
Furthermore , we emulate an SDN testbed on top of the FutureGrid virtualized testbed and use it to evaluate our approach for a realistic scientific workflow.  ...  Firstly, we leverage software-defined networking (SDN) to address issues of data transport service control and resource pro-visioning to meet varying QoS requirements from multiple coupled workflows sharing  ...  Our work is more focused on enabling efficient wide-area workflow couplings than managing whole workflow execution over the Grid as in AutoFlow.  ... 
fatcat:urb6cbord5e4zpfljawzxtbrba

Medical Cannabis and Industrial Hemp Tissue Culture: Present Status and Future Potential

Dinesh Adhikary, Manoj Kulkarni, Aliaa El-Mezawy, Saied Mobini, Mohamed Elhiti, Rale Gjuric, Anamika Ray, Patricia Polowick, Jan J Slaski, Maxwell P Jones, Pankaj Bhowmik
2021 Frontiers in Plant Science  
methods to create novel phenotypes by gene expression modulation and to validate gene function.  ...  Among the planting materials used for cultivation, tissue culture clones provide various advantages such as economies of scale, production of disease-free and true-to-type plants for reducing the risk  ...  Conventionally, GMO crops refer to organisms that have been altered in a way that they would not have evolved naturally.  ... 
doi:10.3389/fpls.2021.627240 pmid:33747008 pmcid:PMC7968383 fatcat:kr66yod5inds5ptc64mhqjrttu

Autonomic management of data streaming and in-transit processing for data intensive scientific workflows

Viraj N. Bhat
2008
This requires addressing the natural mismatches in the ways data is represented in different workflow components and on a variety of machines, and being able to "outsource" the required data manipulation  ...  The main objectives of this research are: (1) developing an end-to-end QoS management framework for data intensive applications so that it is able to provide robust underlying support for asynchronous,  ...  challenges for Grid workflows. as an alternative to secure copy ("scp") .  ... 
doi:10.7282/t3xs5vrh fatcat:kbobnpunw5ahjiluh4bh4s3ejm

Fast detection of Southern tomato virus by one-step transcription loop-mediated isothermal amplification (RT-LAMP)

L. Elvira-González, A.V. Puchades, C. Carpino, A. Alfaro-Fernandez, M.I. Font-San-Ambrosio, L. Rubio, L Galipienso
2017 Journal of Virological Methods  
Materials and methods:We have developed QuasiFlow, a workflow designed in AutoFlow that takes advantage of NGS technologies to reconstruct quasispecies based in Illumina reads.  ...  ASFV remodels endosomal traffic and redistributes endosomal membranes to the viral replication site in order to build a compact viral replication organelle.  ...  an important public health problem.  ... 
doi:10.1016/j.jviromet.2016.12.004 pmid:27965036 fatcat:5vqbhusk7vajhkvtl7wkufo2na

Identification of novel biomarkers and therapeutic strategies for targeting hnRNPA1 mediated drug resistance in Osteosarcoma

Yueyang Huang, Olivier Pardo, Clement Wheeler-Bennett Memorial Trust
2021
Hence, inhibitors of the FGF2 receptors (FGFRIs) were expected to provide ways to re-sensitize resistant tumours to therapy.  ...  These results highlight the importance of appropriate patient stratification and the associated need to identify novel biomarkers to predict tumour response to FGFR-directed therapy.  ...  In fact, targeting RSK4 has been proven to be an effective way to prevent chemoresistance in breast, lung and bladder cancer [408, 409] .  ... 
doi:10.25560/91602 fatcat:5alnkttkxjflxlsesoiqfx5jia

Integrated multi-scale mathematical models for biologics process development

António Carlos Martins De Jesus Lima Grilo, Athanasios Mantalaris, European Commission
2020
The therapeutic monoclonal antibody (mAb) market is witnessing an unprecedented growth having nearly duplicated since 2012.  ...  Faster regulatory approvals and an increasing number of biosimilars are among the most important mAb market expansion drivers.  ...  Culture flasks were incubated at 37°C, 5% CO 2 and 100% humidity in an AutoFlow 5500E incubator (Nuaire) and orbitally shaken at 130 rpm on a Shaker-07 (SciQuip).  ... 
doi:10.25560/81634 fatcat:kjzseh7c55gw5dd2o55quet4my