A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2018; you can also visit the original URL.
The file type is application/pdf.
Filters
Association between increased magnetic susceptibility of deep gray matter nuclei and decreased motor function in healthy adults
2015
NeuroImage
Preserved Fulltext
Independent of gender, age, and global cognitive function, increasing magnetic susceptibility in the globus pallidus and red nuclei was associated with decreasing manual dexterity. ...
In this study, we explored the correlation between magnetic susceptibility--a surrogate marker of brain iron--of these gray matter structures with behavioral measures of motor and cognitive abilities, ...
Acknowledgment The study is supported by the National Institutes of Health (NIH) through grant R01 MH096979 to C. L. C. L. and A.W. ...
doi:10.1016/j.neuroimage.2014.10.009
pmid:25315786
pmcid:PMC4339282
fatcat:p3jriuquzrbzbdjibuwyt3lwxm
Age-related magnetic susceptibility changes in deep grey matter and cerebral cortex of normal young and middle-aged adults depicted by whole brain analysis
2021
Quantitative Imaging in Medicine and Surgery
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
Our goal was to conduct a detailed analysis of iron deposition patterns in the cerebral deep grey matter and cortex using region-based and whole-brain analyses of brain magnetic susceptibility. ...
Thalamic susceptibility increased until the fourth decade and decreased thereafter with the exception of the pulvinar where susceptibility increase was observed throughout the adult lifespan. ...
Discussion In this study, we quantified age-related changes of magnetic susceptibility in deep grey matter structures and the cerebral cortex in a cohort of adult healthy individuals using whole-brain ...
doi:10.21037/qims-21-87
pmid:34476177
pmcid:PMC8339659
fatcat:xvgh7xiszrbpte7jb3fhw4vmjm
Quantitative susceptibility mapping to evaluate brain iron deposition and its correlation with physiological parameters in hypertensive patients
2021
Annals of Translational Medicine
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
These results are indicative of the role of overload brain iron in deep brain gray matter nuclei in HP and suggest that HP is associated with excess brain iron in certain deep gray matter regions. ...
Differences in brain iron deposition in deep gray matter nuclei of participants were compared between HP and HC. ...
Our results show that excessive iron in the deep gray matter nuclei of the brain plays a role in HP, which suggests HP is associated with excess brain iron in certain deep gray matter regions. ...
doi:10.21037/atm-21-5170
pmid:34790788
pmcid:PMC8576670
fatcat:gj7ejqenwzabppxwjqbivkx7tq
Characterization of Iron Accumulation in Deep Gray Matter in Myotonic Dystrophy Type 1 and 2 Using Quantitative Susceptibility Mapping and R2* Relaxometry: A Magnetic Resonance Imaging Study at 3 Tesla
2019
Frontiers in Neurology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
In this prospective, explorative study the iron accumulation in deep gray matter nuclei (DGM) in myotonic dystrophy type 1 (DM1) and 2 (DM2) and its clinical and neuro-cognitive relevance using susceptibility ...
Quantitative mapping of the magnetic susceptibility and the effective transverse relaxation rate (R2*) are suitable to assess the iron content in distinct brain regions. ...
Likewise, we thank all healthy volunteers for taking part in the MRI examinations. We also thank the staff of the Neurological Clinic (St. ...
doi:10.3389/fneur.2019.01320
pmid:31920940
pmcid:PMC6923271
fatcat:7s7zdk5yp5aqti3b5b2pw6w7ty
Iron Content in Deep Gray Matter as a Function of Age Using Quantitative Susceptibility Mapping: A Multicenter Study
2021
Frontiers in Neuroscience
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
of deep gray matter (DGM) of the human brain using subjects from multiple sites; and to establish a susceptibility baseline as a function of age for each DGM structure using both a global and regional ...
Eight subcortical gray matter nuclei were semi-automatically segmented using a full-width half maximum threshold-based analysis of the QSM data. ...
Kofi (2015) assessed the reproducibility of brain QSM in healthy controls (HC) and Abbreviations: QSM, quantitative susceptibility mapping; DGM, deep gray matter; GRE, gradient echo; HC, healthy controls ...
doi:10.3389/fnins.2020.607705
pmid:33488350
pmcid:PMC7815653
fatcat:7q7smao4szhzzmn3jvgmfzptj4
Increased Magnetic Susceptibility in the Deep Gray Matter Nuclei of Wilson's Disease: Have We Been Ignoring Atrophy?
2022
Frontiers in Neuroscience
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2022; you can also visit the original URL.
The file type is application/pdf.
and total susceptibility of multiple deep gray matter nuclei in patients with WD were higher than those in healthy controls. ...
BackgroundHistopathological studies in Wilson's disease (WD) have revealed increased copper and iron concentrations in the deep gray matter nuclei. ...
In summary, significantly increased mean bulk susceptibility and total susceptibility were observed in the majority of deep gray matter nuclei of both patients with neuro-WD and patients with hep-WD. ...
doi:10.3389/fnins.2022.794375
pmid:35720701
pmcid:PMC9198485
fatcat:f3wth77hnrhmxlmikhfiptw5jy
Longitudinal Study of Iron Deposition and Volume in the Precentral Gyrus in Patients with Relapse-Remitting Multiple Sclerosis
2020
Journal of Biosciences and Medicines
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
The mean phase values (MPVs) and volumes in precentral gyrus gray matter (PGM) were measured, and change of iron content and its correlation with volume, clinical manifestations were analyzed. ...
Methods: Thirty RRMS patients and thirty age-and sex-matched healthy controls were recruited and underwent ESWAN and 3D T 1 WI twice interval of one year with the same parameters. ...
content increased and atrophy in deep brain gray matter nuclei, also concluded that iron deposition and atrophy in deep brain gray matter nuclei are more powerful influence than lesion load of white matter ...
doi:10.4236/jbm.2020.85008
fatcat:un75zc4w3ncnhby3kvx32ac6gm
Neonate and infant brain development from birth to 2 years assessed using MRI-based quantitative susceptibility mapping
2019
NeuroImage
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2022; you can also visit the original URL.
The file type is application/pdf.
The contrast between the gray and white matters on the QSM images did not change through brain development from neonate to adult. ...
Also, the magnetic susceptibility values of the cerebral spinal fluid (CSF) exhibit a gradually decreasing trend from birth to 2 years old and to adulthood. ...
Susceptibility in Deep Gray Matter (DGM) Fig. 6 shows the development of R2* and susceptibility in DGM nuclei at different ages. ...
doi:10.1016/j.neuroimage.2018.10.031
pmid:30315906
pmcid:PMC6292682
fatcat:uoj5pwvvxbf4znc7g7jxs4smu4
Age and sex related differences in subcortical brain iron concentrations among healthy adults
2015
NeuroImage
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Age and sex can influence brain iron levels. We studied the influence of these variables on deep gray matter magnetic susceptibilities. ...
Women expected to be post menopause (+51 years) showed lower total magnetic susceptibility in the subcortical gray matter. ...
Acknowledgments This work was supported in part by a grant: R01EB013443, from the National Institute on Aging to YW, Grants FOA11H-349 & FOA13H-090 from the Royal Swedish Society of Sciences, & Solstickan ...
doi:10.1016/j.neuroimage.2015.07.050
pmid:26216277
pmcid:PMC4737643
fatcat:4rkgsewrlbhpjenx3pkkv432g4
Correlation of dystonia severity and iron accumulation in Rett syndrome
2021
Scientific Reports
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
In this study, we investigated the iron accumulation in deep gray matter of RTT and its correlation with dystonia severity. ...
Abnormal iron accumulation in deep gray matter were reported in some Parkinsonian-related disorders. ...
that accumulation of iron in deep brain nuclei may associate to extrapyramidal symptoms. ...
doi:10.1038/s41598-020-80723-1
pmid:33436916
fatcat:eh4wzplgb5cyjaa7nnprrfx46i
Neuroimaging of Basal Ganglia in Neurometabolic Diseases in Children
2020
Brain Sciences
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2020; you can also visit the original URL.
The file type is application/pdf.
Neuroimaging of basal ganglia in neurometabolic diseases is helpful in early diagnosis and monitoring of changes for optimal therapy. ...
This review focuses on neuroimaging of basal ganglia and its role in the differential diagnosis of inborn errors of metabolism. ...
Changes in deep nuclei are more typical of infantile GM2, whereas juvenile and adult forms present with cerebellar hypo/atrophy. ...
doi:10.3390/brainsci10110849
pmid:33198265
pmcid:PMC7697699
fatcat:bqrdtocxjzcwbf3iuzeyrzk7ha
Brain iron and metabolic abnormalities in C19orf12 mutation carriers: A 7.0 tesla MRI study in mitochondrial membrane protein–associated neurodegeneration
2019
Movement Disorders
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
The aim of this study was to quantify iron concentrations in deep gray matter structures using quantitative susceptibility mapping MRI and to characterize metabolic abnormalities in the pyramidal pathway ...
MR spectroscopy revealed significantly increased levels of glutamate, taurine, and the combined concentration of glutamate and glutamine in membrane protein-associated neurodegeneration, which may be a ...
Volumetric analysis of deep gray matter nuclei did not show any significant differences between C19orf12 mutation heterozygotes and age-matched controls. ...
doi:10.1002/mds.27827
pmid:31518459
fatcat:q5yg364acjbjrnfzvgoh4sbzse
R2 * and quantitative susceptibility mapping in deep gray matter of 498 healthy controls from 5 to 90 years
2021
Human Brain Mapping
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is application/pdf.
This study reports both transverse relaxation rate (R2*) and quantitative susceptibility mapping (QSM) of four primary deep gray matter regions (thalamus, putamen, caudate, and globus pallidus) in 498 ...
Putative MRI markers of iron in deep gray matter have demonstrated age related changes during discrete periods of healthy childhood or adulthood, but few studies have included subjects across the lifespan ...
Only a limited number of studies have reported both QSM and R2* in deep gray matter of healthy populations, and include studies of infants , adolescents (Peterson et al., 2019) or adults (Betts, Acosta-Cabronero ...
doi:10.1002/hbm.25569
pmid:34184808
pmcid:PMC8410539
fatcat:gtjypmeevrcw3jx5s3onjp2gyy
Quantitative Susceptibility Mapping: Contrast Mechanisms and Clinical Applications
2015
Tomography
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf.
This article reviews the mechanism that generates susceptibility contrast within tissues and some associated applications. ...
More importantly, magnetic susceptibility directly reflects the molecular composition and cellular architecture of the tissue. ...
For instance, OEF decreased by 40% in the straight sinus and in the internal cerebral veins that drain the deep gray matter (110) . ...
doi:10.18383/j.tom.2015.00136
pmid:26844301
pmcid:PMC4734903
fatcat:asrfxxhhcrbpnobdc3hjkhnlfq
T2 Shortening in the Visual Cortex
1999
Journal of neuro-ophthalmology
Preserved Fulltext
A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is application/pdf.
The signal intensity of the motor cortex decreased rapidly after the age of 50 years. ...
On T2-weighted spin-echo images, the signal intensity of the visual, motor, and sensory cortices was divided into three grades and compared with the signal intensity of the frontal subcortical white matter ...
In healthy adults, decreased signal intensity on T2-weighted images is seen in the globus pallidi, red nuclei, substantia nigra, and dentate nuclei (4 -6) . ...
doi:10.1097/00041327-199906000-00035
fatcat:zrq4e3w3h5gfpbp3ukafk2ha4i
« Previous
Showing results 1 — 15 out of 1,408 results