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PERFORM: A System for Monitoring, Assessment and Management of Patients with Parkinson's Disease

Alexandros Tzallas, Markos Tsipouras, Georgios Rigas, Dimitrios Tsalikakis, Evaggelos Karvounis, Maria Chondrogiorgi, Fotis Psomadellis, Jorge Cancela, Matteo Pastorino, María Waldmeyer, Spiros Konitsiotis, Dimitrios Fotiadis
2014 Sensors  
In this paper, we describe the PERFORM system for the continuous remote monitoring and management of Parkinson's disease (PD) patients.  ...  The performance of the system has been evaluated in real life conditions, the accuracy and acceptability of the system by the PD patients and healthcare professionals has been tested, and a comparison  ...  M.T.A.W. and D.I.F made substantial contributions in the data analysis and interpretation, in the concept definition and in the critical revision of the article.  ... 
doi:10.3390/s141121329 pmid:25393786 pmcid:PMC4279536 fatcat:4ctonljfgbfwbfhiejhnnkoeuq


Marya Lokhandwala, 11/12, Thube Park, Shivajinagar, Pune, Maharashtra, India., Vivek Kulkarni, Manasa Nair, 11/12, Thube Park, Shivajinagar, Pune, Maharashtra, India., 11/12, Thube Park, Shivajinagar, Pune, Maharashtra, India.
2019 International Journal of Physiotherapy and Research  
There are five Parkinson's disease is the second most common, progressive multi-system neurodegenerative disease affecting people mainly in later years of life [1] .  ...  of movement in Parkinson's patients.  ... 
doi:10.16965/ijpr.2019.160 fatcat:pni2uchpivaobi46x4x7pyew5a

Regional cerebral cholinergic nerve terminal integrity and cardinal motor features in parkinson's disease

Nicolaas I Bohnen, Prabesh Kanel, Robert A Koeppe, Carlos A Sanchez-Catasus, Kirk A Frey, Peter Scott, Gregory M Constantine, Roger L Albin, Martijn L T M Müller
2021 Brain Communications  
Clinical effects of anti-cholinergic drugs implicate cholinergic systems alterations in the pathophysiology of some cardinal motor impairments in Parkinson's disease.  ...  Emphasizing the utility of a systems-network conception of the pathophysiology of Parkinson's disease cardinal motor features, our results are consistent with specific deficits in basal forebrain corticopetal  ...  We are indebted to the subjects who participated in this study.  ... 
doi:10.1093/braincomms/fcab109 pmid:34704022 pmcid:PMC8196256 fatcat:4e5zokysoje4hc5qxmilxobqty

Mobile Systems as a Challenge for Neurological Diseases Management – The Case of Parkinson's Disease [chapter]

Laura Pastor-Sanz, Mario Pansera, Jorge Cancela, Matteo Pastorino, Maria Teresa Arredondo Waldmeyer
2011 Diagnostics and Rehabilitation of Parkinson's Disease  
PERFORM project A sophisticated multi-paRametric system FOR the continuous effective assessment and Monitoring of motor status in Parkinson's disease and other neurodegenerative diseases research project  ...  Comparison with SoA systems Compared to Kinesia system, a sophisticated multi-paRametric system FOR the continuous effective assessment and Monitoring of motor status in Parkinson's disease and other neurodegenerative  ... 
doi:10.5772/16729 fatcat:egrrgx7ac5ehrdfbrd4ltfhn4a

Dopamine-dependent scaling of subthalamic gamma bursts with movement velocity in patients with Parkinson's disease

Roxanne Lofredi, Wolf-Julian Neumann, Antje Bock, Andreas Horn, Julius Huebl, Sandy Siegert, Gerd-Helge Schneider, Joachim K Krauss, Andrea A Kühn
2018 eLife  
We propose that insufficient recruitment of fast gamma bursts during movement may underlie bradykinesia as one of the cardinal symptoms in Parkinson's disease.  ...  Here, disease-specific characteristics of this synchronization and the dopamine-dependence of its scaling in Parkinson's disease are investigated.  ...  Acknowledgements We would like to thank all patients for their participation. Additional information  ... 
doi:10.7554/elife.31895 pmid:29388913 pmcid:PMC5819947 fatcat:ysovwqqtjrda5lnqncxev7zcp4

The BRadykinesia Akinesia INcoordination (BRAIN) tap test: capturing the sequence effect [article]

Hasan Hasan, Maggie Burrows, Dilan S. Athauda, Bruce Hellman, Ben James, Tom Warner, Thomas Foltynie, Gavin Giovannoni, Andrew J. Lees, Alastair J. Noyce
2018 bioRxiv   pre-print
AbstractBackgroundThe BRAIN tap test is an online keyboard tapping task that has been previously validated to assess upper limb motor function in Parkinson's disease (PD).ObjectivesTo develop a new parameter  ...  motor dysfunction in PD, which now includes a measure of bradykinesia.  ...  Ethical standards Studies have been approved by the appropriate ethics committee and have, therefore, been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki  ... 
doi:10.1101/453852 fatcat:ajccxmjozvdrlaozqhkcwt5jyi

Guidelines for the economic analysis of a telematic platform for Parkinson's disease monitoring

Jorge Cancela, Maria T. Arredondo, Olivia Hurtado
2013 13th IEEE International Conference on BioInformatics and BioEngineering  
PERFORM (A sophisticated multi-parametric system FOR the continuous effective assessment and monitoring of motor status in Parkinson's disease and other neurodegenerative diseases) is an European project  ...  for the use of these methodologies in the assessment of telehealth systems focused on PD patients.  ...  Usually a telemedicine program evolves through a known number of stages [2] : a) Pilot or introductory phase, focus on demonstrate the feasibility of the system (limited numbers of patients); b) a routine  ... 
doi:10.1109/bibe.2013.6701606 dblp:conf/bibe/CancelaAH13 fatcat:5yqgccranjc6fk5tzoxihqslqy

A telehealth system for Parkinson's disease remote monitoring. The PERFORM approach

Jorge Cancela, Matteo Pastorino, Maria T. Arredondo, Olivia Hurtado
2013 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)  
This paper summarizes the experience and the lessons learned from the European project PERFORM (A sophisticated multi-parametric system FOR the continuous effective assessment and monitoring of motor status  ...  PERFORM is aimed to provide a telehealth system for the remote monitoring of Parkinson's disease patients (PD) at their homes. This paper explains the global experience with PERFORM.  ...  Research by Jorge Cancela has been partly supported by a PICATA predoctoral fellowship of the Moncloa Campus of International Excellence (UCM-UPM).  ... 
doi:10.1109/embc.2013.6611291 pmid:24111478 dblp:conf/embc/CancelaPAH13 fatcat:5clhdgu4frcixj4ouzryu2ywcq

Sensory Dissociation in Vestibular Function Assessment

Ivan Tolmachev, Konstantin Brazovsky, Sergey Schadenko, Ekaterina Korzhenkova, V.N. Borikov, A.G. Dolgih, V.S. Ivanova, A.A. Ignatovskaya
2016 MATEC Web of Conferences  
Consequently, the development of methods to assess functional state of the equilibrioception system becoming viable in order to detect neurodegenerative disorders as early as possible, to control treatment  ...  The balanced upright position is a result of interaction between vestibular system, skeleton and muscles, visual, and proprioceptive systems.  ...  Thus, a correlation between Parkinson's disease, disorders of the vestibular system and physical balance shows the importance of the study and balance evaluation of patients with Parkinson's disease.  ... 
doi:10.1051/matecconf/20164805005 fatcat:d6nwbzmkcffwfh5cgmq4zywtve

Subthalamic deep brain stimulation sweet spots and hyperdirect cortical connectivity in Parkinson's disease

Harith Akram, Stamatios N. Sotiropoulos, Saad Jbabdi, Dejan Georgiev, Philipp Mahlknecht, Jonathan Hyam, Thomas Foltynie, Patricia Limousin, Enrico De Vita, Marjan Jahanshahi, Marwan Hariz, John Ashburner (+2 others)
2017 NeuroImage  
Firstly, to identify subthalamic region stimulation clusters that predict maximum improvement in rigidity, bradykinesia and tremor, or emergence of side-effects; and secondly, to map-out the cortical fingerprint  ...  Resting tremor in Parkinson's disease is thought to be pathologically separate from bradykinesia and rigidity.  ...  Conclusion The optimal DBS site for patients with Parkinson's disease for tremor, bradykinesia and rigidity appears to correspond to different areas in the motor STN.  ... 
doi:10.1016/j.neuroimage.2017.07.012 pmid:28711737 pmcid:PMC6581538 fatcat:hxrffwbmfrdjbhfu6u3i3w3pum

Feasibility Study of a Wearable System Based on a Wireless Body Area Network for Gait Assessment in Parkinson's Disease Patients

Jorge Cancela, Matteo Pastorino, Maria Arredondo, Konstantina Nikita, Federico Villagra, Maria Pastor
2014 Sensors  
The analysis addresses the assessment of the system performance working in real environments.  ...  Parkinson's disease (PD) alters the motor performance of affected individuals.  ...  Experimental Section Framework -A sophisticated multi-parametric system FOR the continuous effective assessment and Monitoring of motor status in Parkinson's disease and other neurodegenerative diseases  ... 
doi:10.3390/s140304618 pmid:24608005 pmcid:PMC4003960 fatcat:xeimswn2qfh6fhdiklfuo7ftlm

Effectiveness of Virtual Reality Training for Hand Dexterity in Parkinson's Subjects

G Vaishnavi, P Saranya, C.V Senthil Nathan, K Kamatchi, V Pavithralotchani, I Deepa, K Pradeepa, A Sumitha
2022 International Journal of Life Science and Pharma Research  
Parkinson's disease is one of the most common neurodegenerative disorders.  ...  Parkinson's disease (PD) includes multi level impairments in functional, motor activities which leads to worsening the patient's physical and psychological disabilities, more than 10 million people worldwide  ...  Amongst the cardinal symptoms of Parkinson's disease, bradykinesia (i.e. slow movement) is considered to have a large adverse influence on the position of life.  ... 
doi:10.22376/ijpbs/lpr.2022.12.4.l69-77 fatcat:gccwcdohazdvvf3tvlrqsjuwo4

An Integrated Ontology-Based Model for the Early Diagnosis of Parkinson's Disease [chapter]

Athanasios Alexiou, Maria Psiha, Panayiotis Vlamos
2012 IFIP Advances in Information and Communication Technology  
In this paper the general architecture of an integrated multi-scale ontology-based modeling technology for early diagnosis of PD and for progress monitoring is proposed.  ...  In our days there is no single test or biomarker that can predict whether a particular person will develop Parkinson Disease and a definitive diagnosis is only possible after death, with postmortem analysis  ...  PD should be regarded as a multi-regional, multi-system neurodegenerative disorder in which the pathology appears in a regionally specific sequence [11] .  ... 
doi:10.1007/978-3-642-33412-2_45 fatcat:273axadgjvcqbfyp2o5elbnxj4

Application of AI for Analysis of Parkinson's Disease

Harsh Pandey, IT Professional, Department of Information Technology, Manipal University Jaipur (Rajasthan), India., Arjun Shivnani, Aryaman Chauhan, Aditya Pratap Singh, Pauras Khadakban, IT Professional, Department of Information Technology, Manipal University Jaipur (Rajasthan), India., IT Professional, Department of Information Technology, Manipal University Jaipur (Rajasthan), India., IT Professional, Department of Information Technology, Manipal University Jaipur (Rajasthan), India., IT Professional, Department of Information Technology, Manipal University Jaipur (Rajasthan), India.
2021 International journal of soft computing and engineering  
Parkinson's disease is an issue of the central tactile framework that impacts advancement provoking shudders.  ...  Henceforth to make strong proof that vocalization data and the handwriting test from a patient can assist with dissecting whether they experience the evil impacts of Parkinson's.  ...  Parkinson's is a reformist sickness that causes degeneration of the brain, inciting both motor and scholarly issues. Parkinson's Disease signs decay as the condition progresses as time goes on.  ... 
doi:10.35940/ijsce.a3527.0911121 fatcat:ts2sa5ruxnbt5jpjriueziww4i

A novel conceptual framework for balance training in Parkinson's disease-study protocol for a randomised controlled trial

David Conradsson, Niklas Löfgren, Agneta Ståhle, Maria Hagströmer, Erika Franzén
2012 BMC Neurology  
in Parkinson's disease.  ...  Assessment will be conducted through a multi-dimensional battery of outcomes, prior to and immediately after the 10-week intervention, and at 9 and 15 months' follow-up after entering the study.  ...  Acknowledgement The authors acknowledge Professor Johan Lökk for valuable discussions regarding assessment of Parkinson's disease medication.  ... 
doi:10.1186/1471-2377-12-111 pmid:23017069 pmcid:PMC3482553 fatcat:pejzffitp5esxn6sy3pkoecwrm
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