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VP25.07: Impact of maternal anxiety on thalamocortical fetal functional development

M. Caglioni, F. Tiberio, M. Pozzoni, S. Spinillo, M. Candiani, A. Falini, C. Baldoli, M. Canini, P.A. Della Rosa, P.I. Cavoretto
2020 Ultrasound in Obstetrics and Gynecology  
VP25.05 Assessment of fetal Sylvian fissure development by 3D-MPR sonography in axial and coronal planes between 23 and 34 weeks.  ...  These results reinforce the utility of evaluating Sylvian fissure in routine ultrasound to increase the diagnosis of MDC.  ...  Conclusions: Sonographic assessment of the fetal SF biometry in the standard 3D-MPR axial and coronal planes is feasible and correlates well with gestational age.  ... 
doi:10.1002/uog.22718 fatcat:qmpvg7d6fncgxoslmgasj4mlby

Role of Ultrasonography in the Evaluation of Normal Developmental Pattern of Fetal Cerebral Sulci Between 18 and 32 Weeks of Gestational Age

Chaithanya A, Anil K Sakalecha, Srinivasa B.C.R.
2022 Cureus  
Knowledge of normal development patterns of fetal cerebral sulci helps in early suspicion and detection of these cortical malformations, when present.  ...  The mean age of antenatal mothers was 24.09 ± 4.13 years, and the mean fetal gestational age was 24.99 ± 4.13 weeks.  ...  Assessment of fetal sulcal development to understand the cortical maturation through sonography has now become widespread.  ... 
doi:10.7759/cureus.22581 pmid:35355543 pmcid:PMC8957649 fatcat:2fmwi6klszgxnpg3afbqmxvdme

Fetal cerebellar growth and Sylvian fissure maturation: International standards from the Fetal Growth Longitudinal Study of the INTERGROWTH-21st Project

María j. Rodriguez-Sibaja, José Villar, Eric O. Ohuma, Raffaele Napolitano, Sabrina Heyl, Maria Carvalho, Yasmin A. Jaffer, J. Alison Noble, Manuela Oberto, Manorama Purwar, Ruyan Pang, Leila Cheikh Ismail (+8 others)
2020 Ultrasound in Obstetrics and Gynecology  
Of those children in the original FGLS cohort who had developmental assessment at 2 years of age, 1130 also had an available 3D ultrasound fetal head volume.  ...  In the present analysis, only those fetuses that underwent developmental assessment at 2 years of age were included.  ...  Acknowledgments funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.  ... 
doi:10.1002/uog.22017 pmid:32196791 fatcat:fqxagxl2mrb43arf5usph6v3ca

3D Morphometric Analysis of Human Fetal Cerebellar Development

Julia A. Scott, Kia S. Hamzelou, Vidya Rajagopalan, Piotr A. Habas, Kio Kim, A. James Barkovich, Orit A. Glenn, Colin Studholme
2011 Cerebellum  
To date, growth of the human fetal cerebellum has been estimated primarily from linear measurements from ultrasound and 2D magnetic resonance imaging (MRI).  ...  In this study, we use 3D analytical methods to develop normative growth trajectories for the cerebellum in utero.  ...  In one study, cerebellar volume was estimated from multiplanar measurements of 3D ultrasound [14] and in another from 3D reconstructed fetal MRI [15] . 2D fetal MRI has also been used to replicate ultrasonography  ... 
doi:10.1007/s12311-011-0338-2 pmid:22198870 pmcid:PMC3389138 fatcat:zyxdgatzcng77fw4dzjwpvb3wm

Prenatal Ultrasound Diagnosis of Biometric changes in the Brain of Growth Restricted Fetuses. A Systematic Review of Literature
Diagnóstico ecográfico de alterações biométricas no cérebro de fetos com restrição do crescimento fetal. Uma revisão sistemática da literatura

Patrícia Isabel Pereira Silva, Miriam Perez
2021 Revista Brasileira de Ginecologia e Obstetrícia  
The purpose of the present revision is to perform a literature search for evidence on the detection and assessment by ultrasound of brain injury linked to FGR during fetal life.  ...  Fetal growth restriction (FGR) occurs when the fetus does not reach its intrauterine potential for growth and development as a result of compromise in placental function.  ...  through gestation and a second- degree correlation was found between gestational age and CC outer margin.The average growth in normal fetuses was 0.18 cm/week between 19 to 35 weeks of gestation.  ... 
doi:10.1055/s-0041-1730290 pmid:34461665 fatcat:q6uus4fbwna6vomxjzkh42nzya

The association between flow and oxygenation and cortical development in fetuses with congenital heart defects using a brain‐age prediction algorithm

Sheila M.P. Everwijn, Ana I.L. Namburete, Nan Geloven, Fenna A.R. Jansen, Aris T. Papageorghiou, Aalbertine K. Teunissen, Lieke Rozendaal, Nico Blom, Jan M. Lith, Monique C. Haak
2020 Prenatal Diagnosis  
The aim of the current study is to analyze fetal brain development based on hemodynamic differences, using novel brain-age prediction software.  ...  An algorithm that assesses the degree of fetal brain-age automatically was used to compare CHD cases to controls.  ...  In these studies the depth of several fissures (eg, POF, SF, central sulcus, and calcarine sulcus) were measured manually to represent cortical development.  ... 
doi:10.1002/pd.5813 pmid:33448406 pmcid:PMC7891604 fatcat:dznqzrsh5zbgreosjo72ddhhmi

Early Folding Patterns and Asymmetries of the Normal Human Brain Detected from in Utero MRI

P. A. Habas, J. A. Scott, A. Roosta, V. Rajagopalan, K. Kim, F. Rousseau, A. J. Barkovich, O. A. Glenn, C. Studholme
2011 Cerebral Cortex  
Using structural information from in utero MRI, we perform morphometric analysis of cortical plate surface development and modeling of early folding in the normal fetal brain.  ...  First, we identify regions of the fetal brain surface that undergo significant folding changes during this developmental period and provide precise temporal staging of these changes for each region of  ...  Funding National Institutes of Health (R01 NS 055064 to C.S., K23 NS 052506 to O.A.G.); European Research Council (FP7/2007-2013. Notes Conflict of Interest: None declared.  ... 
doi:10.1093/cercor/bhr053 pmid:21571694 pmcid:PMC3236791 fatcat:qflxjyvauzehtffnzojjvoctea

Spatial–temporal atlas of human fetal brain development during the early second trimester

Jinfeng Zhan, Ivo D. Dinov, Junning Li, Zhonghe Zhang, Sam Hobel, Yonggang Shi, Xiangtao Lin, Alen Zamanyan, Lei Feng, Gaojun Teng, Fang Fang, Yuchun Tang (+3 others)
2013 NeuroImage  
In this study, 34 postmortem human fetal brains with gestational ages ranging from 15 to 22 weeks were scanned using 7.0 T MR.  ...  These atlases were used for the analysis of age-specific shape changes during this period, including development of the cerebral wall, lateral ventricles, Sylvian fissure, and growth direction based on  ...  Acknowledgments This study was supported by the National Natural Science Foundation of China (No. 31071050; No. 81001223  ... 
doi:10.1016/j.neuroimage.2013.05.063 pmid:23727529 pmcid:PMC3876574 fatcat:2kh4do6tkbajvh3k2bakb4oe3q

Volumetric and surface-based 3D MRI analyses of fetal isolated mild ventriculomegaly

Julia A. Scott, Piotr A. Habas, Vidya Rajagopalan, Kio Kim, A. James Barkovich, Orit A. Glenn, Colin Studholme
2012 Brain Structure and Function  
Diagnosis of fetal isolated mild ventriculomegaly (IMVM) is the most common brain abnormality on prenatal ultrasound.  ...  Linear models were estimated for age-related and ventricular volume-associated changes in local curvature in both the inner cortical plate and ventricles.  ...  Over this period of gestational development, progression in cortical folding was evident (Fig. 7a) .  ... 
doi:10.1007/s00429-012-0418-1 pmid:22547094 fatcat:ypv3o6ucxzcrlhy4shls4ftrq4

Growth trajectories of the human fetal brain tissues estimated from 3D reconstructed in utero MRI

Julia A. Scott, Piotr A. Habas, Kio Kim, Vidya Rajagopalan, Kia S. Hamzelou, James M. Corbett-Detig, A. James Barkovich, Orit A. Glenn, Colin Studholme
2011 International Journal of Developmental Neuroscience  
Further application of the automated fetal brain segmentation to later gestational ages will bridge the gap between volumetric studies of premature brain development and normal brain development in utero  ...  In the latter half of gestation (20 to 40 gestational weeks), human brain growth accelerates in conjunction with cortical folding and the deceleration of ventricular zone progenitor cell proliferation.  ...  We thank Jan Lui and Arnold Kreigstien for consultation on fetal brain anatomy. We thank participating mothers who have made this research possible.  ... 
doi:10.1016/j.ijdevneu.2011.04.001 pmid:21530634 pmcid:PMC3315847 fatcat:eaueohz4mjajvez3c4patprrpe

Brain volumetry in fetuses that deliver very preterm: an MRI pilot study

Lisa Story, Alice Davidson, Prachi Patkee, Bobbi Fleiss, Vanessa Kyriakopoulou, Kathleen Colford, S. Srividhya Sankaran, Paul Seed, Alice Jones, Jana Hutter, Andrew Shennan, Mary Rutherford
2021 NeuroImage: Clinical  
Fetal MRI was performed on a 1.5 T or 3 T MRI scanner: T2-weighted images were obtained of the fetal brain. 3D brain volumetric datsets were produced using slice to volume reconstruction and regional segmentations  ...  If alterations in brain development are commencing antenatally in fetuses that subsequently deliver preterm, this may present a window for in utero therapy in the future.  ...  the 3D fetal brain with an accuracy of 0.3 mm.  ... 
doi:10.1016/j.nicl.2021.102650 pmid:33838546 pmcid:PMC8045030 fatcat:7e2npqshb5dr7gaxrfinwz6rz4

Automatic quantification of normal cortical folding patterns from fetal brain MRI

R. Wright, V. Kyriakopoulou, C. Ledig, M.A. Rutherford, J.V. Hajnal, D. Rueckert, P. Aljabar
2014 NeuroImage  
Automatic quantification of normal cortical folding patterns from fetal brain MRI. NeuroImage, 91, 21-32. *7.  ...  Manuscript Click here to view linked References growth rate were detected, with the parietal and posterior temporal lobe exhibiting the fastest growth, while the cingulate, frontal and medial temporal lobe developed  ...  The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health.  ... 
doi:10.1016/j.neuroimage.2014.01.034 pmid:24473102 fatcat:nycoe3ububegbnzemtlyacf26q

Fetal Central Nervous System Abnormalities [chapter]

Andreea Ceausescu, Andreea Docea, Marina Dinu, Stefan Degeratu, Dominic Iliescu, Monica Cara
2018 Congenital Anomalies - From the Embryo to the Neonate  
Due to the evolving pattern, ultrasound screening for fetal brain malformations is usually performed at 19-22 weeks' gestation, but severe congenital anomalies can be diagnosed much earlier.  ...  This chapter is a short review, structured in eight subchapters: the first one is dedicated to the normal ultrasound aspect of different CNS segments, and the following ones are to detect pathology in  ...  The transversal diameter of the cerebellum (in mm) equals roughly the gestational age (in weeks).  ... 
doi:10.5772/intechopen.76208 fatcat:r2i46gzyqba7llktmnhahpmp4q

Fetal Brain Development: Regulating Processes and Related Malformations

Zvi Leibovitz, Tally Lerman-Sagie, Leila Haddad
2022 Life  
This paper describes the contemporary state of knowledge regarding processes that regulate normal development of the embryonic–fetal central nervous system (CNS).  ...  The processes are described according to the developmental timetable: dorsal induction, ventral induction, neurogenesis, neuronal migration, post-migration neuronal development, and cortical organization  ...  Conflicts of Interest: The authors declare no conflict of interest.  ... 
doi:10.3390/life12060809 pmid:35743840 pmcid:PMC9224903 fatcat:5z6ty2o2iffhvjgjvhovqp74r4

MRI assessment of neonatal brain maturation

Nadine J Girard, Philippe Dory-Lautrec, Mériam Koob, Anca Melania Dediu
2012 Imaging in Medicine  
gestational age and white matter organization.  ...  Computational automated techniques are emerging that help to generate a 3D fetal atlas by motion-corrected high resolution images, to more precisely identify volumetric brain growth, cortical folding over  ...  Software based on segmentation are emerging and are necessary to more precisely identify volumetric brain growth, and cortical folding over gestational age (GA) [43] .  ... 
doi:10.2217/iim.12.59 fatcat:pd45kjmxrzhwfgfdydxvi7dbaq
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