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PET/CT and PET/MRI in ophthalmic oncology (Review)

Maria Kalemaki, Apostolos Karantanas, Dimitris Exarchos, Efstathios Detorakis, Odysseas Zoras, Kostas Marias, Corina Millo, Ulas Bagci, Ioannis Pallikaris, Andreas Stratis, Ioannis Karatzanis, Kostas Perisinakis (+5 others)
2020 International Journal of Oncology  
Aim of the current review is to discuss the current applications of hybrid PET/CT and PET/MRI imaging in the management of patients presenting with the most commonly encountered orbital and ocular tumors  ...  coherence tomography (OCT)‑angiography, computed tomography (CT) and magnetic resonance imaging (MRI).  ...  in the Preservation of Cultural Heritage and the Tackling of Societal Challenges').  ... 
doi:10.3892/ijo.2020.4955 pmid:31939615 pmcid:PMC6959466 fatcat:3juadk4ceneurivxi5k4n4or64

Diagnostic utility of 68Ga-citrate and 18FDG PET/CT in sarcoidosis patients

Cuneyt Tetikkurt, Halil Yanardag, Burcak Haluk Sayman, Muammer Bilir, Seza Tetikkurt, Seckin Bilgic, Bahar Kubat, Seyda Bilgin
2020 Monaldi archives for chest disease  
emission tomography with 2-deoxy-2-[fluorine-18] fluoro-D-glucose integrated with computed tomography (18F-FDG PET/CT)] imaging in sarcoidosis patients.  ...  A total of eight sarcoidosis patients with a comorbid disease suspicion were included in the study.  ...  appears to be a significant alternative to 18 F-FDG PET/CT, 67 Ga-citrate scintigraphy, computed tomography (CT) to identify disease activity and organ involvement in sarcoidosis patients [5] [6] [  ... 
doi:10.4081/monaldi.2020.1509 pmid:33372740 fatcat:gx5y7zctvnd5pbkl5f2gvf3rja

Structural-functional relationships between eye orbital imaging biomarkers and clinical visual assessments

Xiuya Yao, Shikha Chaganti, Kunal P. Nabar, Katrina Nelson, Andrew Plassard, Rob L. Harrigan, Louise A. Mawn, Bennett A. Landman, Elsa D. Angelini, Martin A. Styner
2017 Medical Imaging 2017: Image Processing  
for patients (with thyroid eye disease, orbital inflammation, optic nerve edema, glaucoma, intrinsic optic nerve disease), clinical imaging, and visual function assessments.  ...  Orbital magnetic resonance imaging (MRI) and computed tomography (CT) images were retrieved and labeled in 3D using multi-atlas label fusion.  ...  Author manuscript; available in PMC 2017 July 21.  ... 
doi:10.1117/12.2254613 pmid:28736470 pmcid:PMC5521276 dblp:conf/miip/YaoCNNPHML17 fatcat:a7hvanjklja7laam27fa4yjoci

Phenotype analysis of early risk factors from electronic medical records improves image-derived diagnostic classifiers for optic nerve pathology

Shikha Chaganti, Kunal P. Nabar, Katrina M. Nelson, Louise A. Mawn, Bennett A. Landman, Tessa S. Cook, Jianguo Zhang
2017 Medical Imaging 2017: Imaging Informatics for Healthcare, Research, and Applications  
We developed an automated image-processing pipeline that identifies the orbital structures within the human eyes from computed tomography (CT) scans, calculates structural size, and performs volume measurements  ...  disease, 0.72 to 0.76 for optic nerve edema, 0.72 to 0.77 for orbital inflammation, and 0.81 to 0.85 for thyroid eye disease.  ...  This study was in part using the resources of the Advanced Computing Center for Research and Education (ACCRE) at Vanderbilt University, Nashville, TN.  ... 
doi:10.1117/12.2254618 pmid:28736474 pmcid:PMC5521270 fatcat:2xmvpf6xovdp7ox4ukodncemci

Radiological Features of Thyroid Eye Disease (TED)

Ayushi Agarwal
2020 Delhi Journal of Ophthalmology  
This article highlights the importance of imaging and its current utility in Thyroid Eye Disease (TED).  ...  Assessment of various disease parameters, surgical planning, characterization of severity and activity, identification of sight-threatening disease and differentiation from other orbital inflammatory disorders  ...  Herein we discuss the two most preferred imaging investigations in TED, Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). proptosis using mid-axial orbital CT scan was first described by Hilal  ... 
doi:10.7869/djo.609 fatcat:krnwnflawrfmdff5i5zeljgfea

FDG-PET/CT pitfalls in oncological head and neck imaging

Bela S. Purohit, Angeliki Ailianou, Nicolas Dulguerov, Christoph D. Becker, Osman Ratib, Minerva Becker
2014 Insights into Imaging  
Objectives Positron emission tomography-computed tomography (PET/CT) with fluorine-18-fluorodeoxy-D-glucose (FDG) has evolved from a research modality to an invaluable tool in head and neck cancer imaging  ...  and correlation with contrast-enhanced CT, US or MRI avoid PET/CT misinterpretation. • Awareness of unusual FDG uptake patterns avoids overdiagnosis of benign conditions as malignancy.  ...  Introduction Positron emission tomography-computed tomography (PET/ CT) with fluorine-18-fluorodeoxy-D-glucose (FDG) plays a major role today in the pre-therapeutic work-up and post-therapeutic monitoring  ... 
doi:10.1007/s13244-014-0349-x pmid:25154759 pmcid:PMC4195840 fatcat:b334xdtaanfzxow3xgd2sqjacq

Radiologic imaging shows variable accuracy in diagnosing orbital inflammatory disease and assessing its activity

Min Joung Lee, Bronwyn E. Hamilton, David Pettersson, Kimberly Ogle, Jennifer Murdock, Roger A. Dailey, John D. Ng, Eric A. Steele, Rohan Verma, Stephen R. Planck, Tammy M. Martin, Dongseok Choi (+1 others)
2020 Scientific Reports  
We collected 75 scans of 52 patients (49 computed tomography (CT) scans; 26 magnetic resonance (MR) imaging scans).  ...  Clinical diagnoses included thyroid eye disease (TED) (41 scans, 31 patients), non-specific orbital inflammation (NSOI) (22 scans, 14 patients), sarcoidosis (4 scans, 3 patients), IgG4-related ophthalmic  ...  Two consecutive magnetic resonance (MR) scans of 1 patient with thyroid eye disease.  ... 
doi:10.1038/s41598-020-78830-0 pmid:33318556 fatcat:gtzjafucfnbpfhos5d7xuhiwyy

Ultrasound, CT, MRI, or PET-CT for staging and re-staging of adults with cutaneous melanoma

Jacqueline Dinnes, Lavinia Ferrante di Ruffano, Yemisi Takwoingi, Seau Tak Cheung, Paul Nathan, Rubeta N Matin, Naomi Chuchu, Sue Ann Chan, Alana Durack, Susan E Bayliss, Abha Gulati, Lopa Patel (+8 others)
2019 The Cochrane library  
Establishing the comparative accuracy of ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET)-CT imaging for detection of nodal or distant metastases  ...  Various imaging tests can be used with the aim of detecting metastatic spread of disease following a primary diagnosis of melanoma (primary staging) or on clinical suspicion of disease recurrence (re-staging  ...  Much of the evidence for whole body imaging for primary staging or re-staging of disease is focused on positron emission tomography-computed tomography (PET-CT), and comparative data with CT or magnetic  ... 
doi:10.1002/14651858.cd012806.pub2 pmid:31260100 pmcid:PMC6601698 fatcat:wsrnwy7avzg3hm666hocr5svme

Endocrine radionuclide scintigraphy with fusion single photon emission computed tomography/computed tomography

Ka-Kit Wong, Arpit Gandhi, Benjamin L Viglianti, Lorraine M Fig, Domenico Rubello, Milton D Gross
2016 World Journal of Radiology  
AIM: To review the benefits of single photon emission computed tomography (SPECT)/computed tomography (CT) hybrid imaging for diagnosis of various endocrine disorders.  ...  RESULTS: The emergence of hybrid SPECT/CT camera technology now allows simultaneous acquisition of combined multi-modality imaging, with seamless fusion of three-dimensional volume datasets.  ...  Graves' eye disease is another area where SPECT/CT could have diagnostic value, with localization of 99m Tc-EDDA/HYNIC-TOC to the orbits on SPECT/CT being positively related to the disease activity.  ... 
doi:10.4329/wjr.v8.i6.635 pmid:27358692 pmcid:PMC4919764 fatcat:kzrm4sigojam3idvfn7jntdmwm

Value of positron emission tomography/computed tomography in diagnosis and staging of primary ocular and orbital tumors

Ka-Hoi Hui, Margaret L. Pfeiffer, Bita Esmaeli
2012 Saudi Journal of Ophthalmology  
Positron emission tomography/computed tomography (PET/CT) has recently emerged as a staging tool in the field of ophthalmic oncology.  ...  Accurate and reliable staging methods are crucial for optimal care of patients with ocular and orbital malignancies.  ...  The authors have no commercial associations or financial disclosures that might pose a conflict of interest with information presented in this manuscript.  ... 
doi:10.1016/j.sjopt.2012.08.008 pmid:23961021 pmcid:PMC3729316 fatcat:hxevckmrinhaxbhvqgoeyu4d6e

Update on thyroid-associated Ophthalmopathy with a special emphasis on the ocular surface

Priscila Novaes, Ana Beatriz Diniz Grisolia, Terry J. Smith
2016 Clinical Diabetes and Endocrinology  
Thyroid-associated ophthalmopathy (TAO) is a condition associated with a wide spectrum of ocular changes, usually in the context of the autoimmune syndrome, Graves' disease.  ...  We also briefly review how increased understanding of the disease should culminate in improved therapies for patients with this vexing condition.  ...  Funding This work was supported in part by National Institutes of Health grants EY008976 and 5UM1AI110557, a Center for Vision grant EY007003 from the National Eye Institute, an unrestricted grant from  ... 
doi:10.1186/s40842-016-0037-5 pmid:28702253 pmcid:PMC5471935 fatcat:ug3qejcn7nffhj5xde2r3enb4u

A combined local and global motion estimation and compensation method for cardiac CT

Qiulin Tang, Beshan Chiang, Akinola Akinyemi, Alexander Zamyatin, Bibo Shi, Satoru Nakanishi, Bruce R. Whiting, Christoph Hoeschen
2014 Medical Imaging 2014: Physics of Medical Imaging  
Simultaneously, we demonstrate the robustness of the optimal algorithm by segmenting the optic nerve structure in 316 CT scans obtained from 182 subjects from a thyroid eye disease (TED) patient population  ...  biological tissue in computed tomography (CT) examinations with the aim of developing two patient equivalent phantoms (PEP).  ...  2 cm) in tens of minutes yielding images containing millions of spectra. Spectra are then automatically classified as one of seven cell-types in prostate tissue in a matter of seconds.  ... 
doi:10.1117/12.2043492 fatcat:fyzpc5m6jbh7fjohqpdmtzkhte

Recent advances in thyroid eye disease: An overview

Sahil Agrawal, Rajendra Prakash Maurya, Ananya P R, Syeed Mehbub UL Kadir, Virendra Pratap Singh, Deepsekhar Das, Saloni Gupta, Vibha Singh, Meghna Roy
2021 IP International Journal of Ocular Oncology and Oculoplasty  
Around 25% of people with Graves' hyperthyroidism are affected by TED, where 1 in 20 patients might report with moderate-to-severe, active disease that will require medical management for reducing both  ...  Thyroid eye disease (TED) is a chronic debilitating condition which causes physical discomfort, oculo-facial disfigurement and compromised visual function.  ...  He observed higher level of serum MDA in TED patients in comparison to Graves' disease patient without TED and healthy controls. 37 Smoking and thyroid eye disease An association of tobacco smoking  ... 
doi:10.18231/j.ijooo.2021.027 fatcat:bqorq7bagzb3jm77wyee7kve6i

Consensus on Diagnostic Criteria of Idiopathic Orbital Inflammation Using a Modified Delphi Approach

Ilse Mombaerts, Jurij R. Bilyk, Geoffrey E. Rose, Alan A. McNab, Aaron Fay, Peter J. Dolman, Richard C. Allen, Martin H. Devoto, Gerald J. Harris
2017 JAMA ophthalmology  
Panelists agreed that a maximum number of 30 IgG4-positive plasma cells per high-power field in the orbital tissue is compatible with the diagnosis of IOI.  ...  Items with dissensus were rescored in the second round, and all items with consensus (median, Ն4; interquartile range, Յ1) were ranked by importance in the third round.  ...  The most accurate assessment of nonmyositic IOI is based on clinical indicators, magnetic resonance imaging (MRI), or computed tomography (CT) studies, selected normal laboratory findings, and incisional  ... 
doi:10.1001/jamaophthalmol.2017.1581 pmid:28570731 pmcid:PMC5710199 fatcat:6r5l6uu775es7k52mkyvcbt3ca

Imaging of Uveal Melanoma—Current Standard and Methods in Development

Małgorzata Solnik, Natalia Paduszyńska, Anna M. Czarnecka, Kamil J. Synoradzki, Yacoub A. Yousef, Tomasz Chorągiewicz, Robert Rejdak, Mario Damiano Toro, Sandrine Zweifel, Katarzyna Dyndor, Michał Fiedorowicz
2022 Cancers  
We reviewed imaging modalities currently used in the diagnostics of uveal melanoma, including fundus imaging, ultrasonography (US), optical coherence tomography (OCT), single-photon emission computed tomography  ...  The principle of imaging techniques is briefly explained, along with their role in the diagnostic process and a summary of their advantages and limitations.  ...  Acknowledgments: Project carried out with the use of CePT infrastructure financed by the European Union-the European Regional Development Fund in the Operational Program "Innovative Economy" for 2007-2013  ... 
doi:10.3390/cancers14133147 pmid:35804919 pmcid:PMC9265106 fatcat:hqcrxw3kpzfdzln4hpu5ltvi54
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