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Structural and Biophysical Comparison of UPEC and ETEC Adhesion Fimbriae

Narges Mortezaei, Bhupender Singh, Esther Bullitt, Johan Zakrisson, Chelsea R. Epler, Krister Wiklund, Magnus Andersson
2015 Biophysical Journal  
Integrating this assembly switch and the nucleotide-dependent interfacial filament stability, our work offers a detailed molecular interpretation of the assembly-disassembly FtsZ cycle and its inhibition  ...  The key stabilization component involved in closing the interfaces in GTP-FtsZ filaments is the coordinated Mg 2þ atom, which the opening GDP filaments lack.  ... 
doi:10.1016/j.bpj.2014.11.2890 fatcat:hvmalvlh5jevjjoi7p24kqmnwa

Development of Tools to Study Retroviral Gag Assembly on Giant Unilamellar Vesicles(GUV)

Yi Wen, Robert Dick, Volker Vogt, Gerald Feigenson
2015 Biophysical Journal  
Integrating this assembly switch and the nucleotide-dependent interfacial filament stability, our work offers a detailed molecular interpretation of the assembly-disassembly FtsZ cycle and its inhibition  ...  The key stabilization component involved in closing the interfaces in GTP-FtsZ filaments is the coordinated Mg 2þ atom, which the opening GDP filaments lack.  ... 
doi:10.1016/j.bpj.2014.11.2887 fatcat:k2chy2clcbg2hjhhjrsv3yvt6y

Molecular Dynamics and Assembly Switch of FtsZ Filaments

Erney Ramírez-Aportela, José Ramón López-Blanco, José Manuel Andreu, Pablo Chacon
2015 Biophysical Journal  
Integrating this assembly switch and the nucleotide-dependent interfacial filament stability, our work offers a detailed molecular interpretation of the assembly-disassembly FtsZ cycle and its inhibition  ...  The key stabilization component involved in closing the interfaces in GTP-FtsZ filaments is the coordinated Mg 2þ atom, which the opening GDP filaments lack.  ... 
doi:10.1016/j.bpj.2014.11.2889 fatcat:nptqnty7hrahlgds7f6ukta6ou

Induced electrostatic charge in poleward motion of chromosomes during mitosis

L. John Gagliardi
2008 Journal of Electrostatics  
(nuclear division) and cytokinesis (cytoplasmic division).  ...  microtubule disassembly forces acting at kinetochores and centrosomes to dominate and anaphase-A motion ensues.  ...  MTs invariably assemble or disassemble at their ends; that is,at some discontinuity in their structure.  ... 
doi:10.1016/j.elstat.2007.11.002 fatcat:blb7pk4uzvbfpd3xuts3gwuhha

Paradigm Shift in the Mechanism of HIV-1 Core Biogenesis

Gabriel A. Frank, Kedar Narayan, Julian W. Bess, Gregory Q. Del Prete, Xiongwu Wu, Amy Moran, Lisa Hartnell, Lesley A. Earl, Jeffrey D. Lifson, Sriram Subramaniam
2015 Biophysical Journal  
Integrating this assembly switch and the nucleotide-dependent interfacial filament stability, our work offers a detailed molecular interpretation of the assembly-disassembly FtsZ cycle and its inhibition  ...  The key stabilization component involved in closing the interfaces in GTP-FtsZ filaments is the coordinated Mg 2þ atom, which the opening GDP filaments lack.  ... 
doi:10.1016/j.bpj.2014.11.2888 fatcat:5ko5ge3xevdjjkzclcsvzap6iy

Electrostatic forces drive poleward chromosome motions at kinetochores

L. John Gagliardi, Daniel H. Shain
2016 Cell Division  
Conclusion: We propose here that implicating Ndc80/Hec1 as a bound volume positive charge distribution in electrostatic generation of poleward force at kinetochores is most consistent with a wide range  ...  negative charge at and near the plus ends of microtubules.  ...  components, and a paper by Powers et al  ... 
doi:10.1186/s13008-016-0026-1 pmid:27807465 pmcid:PMC5086063 fatcat:7knmpjvyyvhbppgyzvhg4akavm

In Vitro Reconstitution of the Initial Stages of the Bacterial Cell Division Machinery

Pilar López Navajas, Germán Rivas, Jesús Mingorance, Pablo Mateos-Gil, Ines Hörger, Enrique Velasco, Pedro Tarazona, Marisela Vélez
2008 Journal of biological physics (Print)  
Fission of many prokaryotes as well as some eukaryotic organelles depends on the self-assembly of the FtsZ protein into a membrane-associated ring structure early in the division process.  ...  Different components of the machinery are then sequentially recruited.  ...  Understanding the interactions between these cell division components will help control their assembly in other artificial systems such as giant liposomes that more closely mimic the curved membrane surface  ... 
doi:10.1007/s10867-008-9118-8 pmid:19669505 pmcid:PMC2577748 fatcat:k24lyub7rvfujaif4jwprfczpe

Electrostatic force generation in chromosome motions during mitosis

L. John Gagliardi
2005 Journal of Electrostatics  
In previous work, I have proposed that nanoscale electrostatics plays a significant role in aster (spindle) assembly and motion, and in force generation at kinetochores and chromosome arms for prometaphase  ...  Microtubule heterodimer subunits are electric dipolar structures that can act as intermediaries, extending electric fields over cellular distances in spite of ionic screening.  ...  Microtubules invariably assemble or disassemble at their ends; that is, at some discontinuity in their structure.  ... 
doi:10.1016/j.elstat.2004.09.007 fatcat:dpys5enkrfe4znwbyxbspc2vyu

Metal-phenolic networks as a versatile platform to engineer nanomaterials and biointerfaces

Hirotaka Ejima, Joseph J. Richardson, Frank Caruso
2017 Nano Today  
delivery, live-cell protection, and catalysis are highlighted.  ...  Research Highlights • We review metal-phenolic networks (MPNs), a versatile class of surface coatings and nanostructured functional materials. • Diverse substrates can be coated owing to the universal  ...  This research was supported by the Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology (project number CE140100036).  ... 
doi:10.1016/j.nantod.2016.12.012 fatcat:3wfh5teanvd4pl2l6vrkejtyve

FtsZ filament capping by MciZ, a developmental regulator of bacterial division

Alexandre W. Bisson-Filho, Karen F. Discola, Patrícia Castellen, Valdir Blasios, Alexandre Martins, Maurício L. Sforça, Wanius Garcia, Ana Carolina M. Zeri, Harold P. Erickson, Andréa Dessen, Frederico J. Gueiros-Filho
2015 Proceedings of the National Academy of Sciences of the United States of America  
Cytoskeletal structures are dynamically remodeled with the aid of regulatory proteins.  ...  Data deposition: The atomic coordinates and structure factors have been deposited in the Protein Data Bank, www.pdb.org [PDB ID codes 4U39 (FtsZ:MciZ complex), and 2MRW (free MciZ)].  ...  Final data collection, structure solution, and refinement statistics are in Table S2 . Right-Angle Light Scattering and FtsZ-BODIPY Assembly/Disassembly Kinetics.  ... 
doi:10.1073/pnas.1414242112 pmid:25848052 pmcid:PMC4418908 fatcat:zuh7hteperhgvcimu5t3p3p3l4

Systems Approach to Mitotic Chromosome Motions

Lucian John Gagliardi
2013 Open Journal of Biophysics  
A clear picture of how kinetochores establish and maintain a dynamic coupling to microtubules for force generation during the complex motions of mitosis remains elusive.  ...  electrostatic interactions in force generation at kinetochores for chromosome motions have prompted speculation regarding possible models for interactions between positively charged molecules in kinetochores and  ...  The factors: 1) an intracellular pH decrease continuing through mitosis; 2) an electrostatic component to microtubule disassembly/assembly probability ratios; 3 na tubule disassembly force ov DeLuca, "  ... 
doi:10.4236/ojbiphy.2013.32017 fatcat:slcn4uafdbgknkpabdp2ao5dlq

Modular Robot Systems

Kyle Gilpin, Daniela Rus
2010 IEEE robotics & automation magazine  
Rob Wood and Dr. Ara Knaian. Keywords Modular robots, self-assembling robots, self-disassembling robots, metamorphic robots.  ...  Army Research Office under grant numbers W911NF-08-1-0228 and W911NF-08-C-0060, National Science Foundation (NSF) Emerging Frontiers in Research and Innovation (EFRI), Intel, and the National Defense Science  ...  during cell division.  ... 
doi:10.1109/mra.2010.937859 fatcat:3xy7o26ikjhshptjbuhl6cpdam

The effect of multivalent cations and Tau on paclitaxel-stabilized microtubule assembly, disassembly, and structure

Cyrus R. Safinya, Peter J. Chung, Chaeyeon Song, Youli Li, Kai K. Ewert, Myung Chul Choi
2016 Advances in Colloid and Interface Science  
In particular, we focus on the effects of multivalent cations, and separately, of microtubule-associated protein (MAP) Tau, on microtubule (MT) ordering (bundling), MT disassembly, and MT structure.  ...  The ion concentration required for depolymerization decreases with increasing atomic number.  ...  and protein based assembly, which lead to hierarchical structures with distinct shapes and functional properties.  ... 
doi:10.1016/j.cis.2015.11.002 pmid:26684364 pmcid:PMC4864139 fatcat:4b36y2bxmzab5oghfuhhrhbv7u

SynopSet: Multiscale Visual Abstraction Set for Explanatory Analysis of DNA Nanotechnology Simulations [article]

Deng Luo, Alexandre Kouyoumdjian, Ondřej Strnad, Haichao Miao, Ivan Barišić, Ivan Viola
2022 arXiv   pre-print
This set is also designed to be capable of showing all spatial and temporal details, and all structural complexity, or abstracting these to various degrees, enabling both the slow playback of the simulation  ...  Further, the novel representations are more intuitive and also enable researchers unfamiliar with MDS analysis graphs to better understand the simulation results.  ...  Such data sets can be used to test, for example, multiscale visualization, automated camera management systems, automated identification of events and smart labeling according to scales and events.  ... 
arXiv:2205.01628v1 fatcat:nr3valvahfg3vikzbpt5bd5dmu

Biomembranes research using thermal and cold neutrons

F.A. Heberle, D.A.A. Myles, J. Katsaras
2015 Chemistry and Physics of Lipids  
Consequently, the coherent neutron scattering length can experience a dramatic change in magnitude and phase as a result of resonance scattering, imparting sensitivity to both light and heavy atoms, and  ...  In 1932 James Chadwick discovered the neutron using a polonium source and a beryllium target (Chadwick 1932) .  ...  Complex assemblies: Structure and organization of photosynthetic systems Understanding the mechanisms that biological systems use to program the self-assembly (and disassembly) of interacting complexes  ... 
doi:10.1016/j.chemphyslip.2015.07.020 pmid:26241882 fatcat:f5wtcxkhpzegdkkljvzoz6rgai
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