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Applying Provenance in Distributed Organ Transplant Management [chapter]

Sergio Álvarez, Javier Vázquez-Salceda, Tamás Kifor, László Z. Varga, Steven Willmott
2006 Lecture Notes in Computer Science  
Here we present a work in progress to apply provenance in the domain of distributed organ transplant management.  ...  The use of ICT solutions applied to Healthcare in distributed scenarios should not only provide improvements in the distributed processes and services they are targeted to assist but also provide ways  ...  Acknowledgements This work has been funded mainly by the IST-2002-511085 PROVENANCE project.  ... 
doi:10.1007/11890850_4 fatcat:pinptdj4rvdyfgdxdvfkhyzhxq

Using SOA Provenance to Implement Norm Enforcement in e-Institutions [chapter]

Javier Vázquez-Salceda, Sergio Alvarez-Napagao
2009 Lecture Notes in Computer Science  
In this paper we describe a way to adapt the HARMONIA framework to be applied in highly regulated Web services and Grid computing scenarios.  ...  In the last 10 years several approaches and technologies other than MAS (such as Web services and Grid computing) have emerged, with the support of the industry, providing their own solutions to distributed  ...  Use Case: The Organ Transplant Management Application The Organ Transplant Management Application (OTMA) is an Agent-Mediated e-Institution for the distribution of organs and tissues for transplantation  ... 
doi:10.1007/978-3-642-00443-8_13 fatcat:asbpurrnjngf3e7gmtgdvxq6py

Provenance in Agent-Mediated Healthcare Systems

Tamas Kifor, Laszlo Varga, Javier Vazquez-Salceda, Sergio Alvarez, Steven Willmott, Simon Miles, Luc Moreau
2006 IEEE Intelligent Systems  
We focus on three aspects of provenance in agent-mediated healthcare systems: first, we define the provenance concept and show how it can be applied to agent-mediated healthcare applications; second, we  ...  Provenance is an innovative approach to trace events in complex distributed processes, dependencies between such events, and associated decisions by human actors.  ...  In Section 3 we describe an organ transplant management application and show how provenance can be applied to that application when agents directly interact.  ... 
doi:10.1109/mis.2006.119 fatcat:bf7jgdl6prgaxizqu26yv3a6fe

Guest Editor's Introduction: On the Evolution of Applying Agent Technology to Healthcare

Antonio Moreno
2006 IEEE Intelligent Systems  
I warmly thank the invaluable international reviewers, who made careful reviews and re-reviews this summer-in most cases, during their holiday periods.  ...  The Carrel project has been working in recent years on developing an agent-mediated electronic institution that can better manage organ and tissue transplants in Spain. 7 In "Increasing Human-Organ Transplant  ...  In "Provenance in Agent-Mediated Healthcare Systems," the authors show how an agent-based healthcare system can appropriately document all the decisions that take place in a distributed setting so that  ... 
doi:10.1109/mis.2006.111 fatcat:ce2lkc72k5d75e2glkyfh6yqba

Access to kidney transplantation: a bioethical perspective

Bruno Lima, Oficina de BioEstatistica, Ermesinde, Helena Alves, Instituto Nacional de Saúde, Dr Ricardo Jorge, Porto
2020 Portuguese Journal of Nephrology and Hypertension  
In accordance with the EBM paradigm, an objective application of distributive justice requires that scarce health resources must be used in treatments of proven effectiveness.  ...  are allocated fairly in treatments of proven clinical value 14 .  ... 
doi:10.32932/pjnh.2020.07.070 fatcat:j4eaimrqajgl5ofif33gtvcn3m

Epidemiological profile and study on waiting lists for corneal transplants in a tertiary hospital

Jacqueline Lunardelli Bittencourt, Ítala de Mores Vieira Gatti, Carolina Falcão Lessa, Luciano Rabello Netto Cirillo, Mariana Gameiro Ierardi, Marina Paulino Garcia, Luiz Antônio de Brito Martins, Fernando Luiz Affonso Fonseca, Vagner Loduca Lima
2020 ABCS Health Sciences  
This information is important, as it helps us to understand the profile of the assisted population and in the organization and planning of the medical team, contributing to better guidance and care for  ...  Conclusion: This study enabled the assessment and knowledge of the epidemiological profile and waiting time for corneal transplantation in our patients.  ...  The distribution of corneas in Brazil is conducted by the Central of Notification, Collection and Distribution of State Organs (CNCDO).  ... 
doi:10.7322/abcshs.2020s07.1854 fatcat:o3rnilpbtfh75mzze7a5kwqxx4

Combined Effects of TGFB1 +869 T/C and +915 G/C Polymorphisms on Acute Rejection Risk in Solid Organ Transplant Recipients: A Systematic Review and Meta-Analysis

Yu-Zheng Ge, Ran Wu, Tian-Ze Lu, Rui-Peng Jia, Ming-Hao Li, Xiao-Fei Gao, Xiao-Min Jiang, Xian-Bo Zhu, Liang-Peng Li, Si-Jia Tan, Qun Song, Wen-Cheng Li (+2 others)
2014 PLoS ONE  
Transforming growth factor-beta 1(TGF-b1) is involved in the development of acute rejection (AR) episodes in solid organ transplant recipients; and a number of studies have been conducted to investigate  ...  In addition, subgroup analysis by transplant types demonstrated a similar association in patients receiving heart transplant (IP vs.  ...  phenotypic distribution in both groups.  ... 
doi:10.1371/journal.pone.0093938 pmid:24705444 pmcid:PMC3976347 fatcat:zwv5tafczzd7bhyzhvttvyld7e

Cytomegalovirus (CMV) Disease Despite Weekly Preemptive CMV Strategy for Recipients of Solid Organ and Hematopoietic Stem Cell Transplantation

I P Lodding, C da Cunha Bang, S S Sørensen, F Gustafsson, M Iversen, N Kirkby, M Perch, A Rasmussen, H Sengeløv, A Mocroft, J D Lundgren
2018 Open Forum Infectious Diseases  
Solid organ transplantation (SOT) and hematopoietic stem cell transplantation (HSCT) recipients with a first episode of CMV polymerase chain reaction (PCR) DNAemia within the first year posttransplantation  ...  Transplant recipients presenting with cytomegalovirus (CMV) disease at the time of diagnosis of CMV DNAemia pose a challenge to a preemptive CMV management strategy.  ...  The funding source had no involvement in any part of the study design, data collection, data analysis, and interpretation of the data or in the writing of this manuscript. Financial support.  ... 
doi:10.1093/ofid/ofy080 pmid:29876364 pmcid:PMC5961206 fatcat:h4o34cn7w5hj3lws5vpldhjn3q

The Incidence of Cytomegalovirus Glycoprotein B Genotypes in Kidney Transplant Recipients in Iran

A R Soleimani, M Jafari, A Piroozmand, H Nikoueinejad, H Akbari, B Einollahi
2018 International journal of organ transplantation medicine  
The most common CMV gB genotype in CMV-infected kidney transplant recipients in Iran was gB1. We recommend considering related therapeutic applications in the management of such patients.  ...  Age (p=0.037), time of infection after transplantation (p=0.011), and biopsy-proven rejection (p=0.012) were associated with CMV genotype.  ...  gB distribution in CMV-infected renal transplant recipients.  ... 
pmid:30863520 pmcid:PMC6409096 fatcat:uhyn2amnqfcjbahuduadx74gfy

Application of Game-like Simulations in the Spanish Transplant National Organization

B. Borro-Escribano, I. Martínez-Alpuente, Á. del Blanco, J. Torrente, B. Fernández-Manjón, R. Matesanz
2013 Transplantation Proceedings  
Twenty years ago, the Spanish National Transplant Organization (NTO) started a management and organizational system, known as the Spanish Model, that has allowed the NTO to occupy a privileged world position  ...  These simulations represent the donor and organ evaluation, the allocation of organs applying the corresponding geographic and clinical criteria, and the logistics of transportation.  ...  Finally, we will enrich 2 of the educational cases, modifying the donor's hospital information to include a hospital in Catalonia and another hospital in Andalusia to improve the coverage of organ distribution  ... 
doi:10.1016/j.transproceed.2013.09.017 pmid:24314959 fatcat:xskfgkuce5dg3c43vg6ppvrlxm


Vladan Borović, Saša Borović, Vida Drąsutė, Dejan Rančić
2018 Facta Universitatis Series Automatic Control and Robotics  
In the well organized transplant programs, all transplantation centers have access to the central computer database.  ...  In this important database, the transplantation centers enter information of their recipients along with the recipient profile and the donor profile.  ...  THE CURRENT SITUATION IN THE WORLD It was proven in many cases that the whole system of donors and transplant candidates, together with transplant hospitals cannot exist without a modern computer information  ... 
doi:10.22190/fuacr1801001b fatcat:gkafw5v57vgi3mbcickifml3xu

The Measurement of Donor-Specific Cell-Free DNA Identifies Recipients With Biopsy-Proven Acute Rejection Requiring Treatment After Liver Transplantation

Su Kah Goh, Hongdo Do, Adam Testro, Julie Pavlovic, Angela Vago, Julie Lokan, Robert M. Jones, Christopher Christophi, Alexander Dobrovic, Vijayaragavan Muralidharan
2019 Transplantation Direct  
Assessment of donor-specific cell-free DNA (dscfDNA) in the recipient is emerging as a noninvasive biomarker of organ rejection after transplantation.  ...  Median levels at days 3, 7, 14, 28, and 42 were 1936, 1015, 247, 90, and 66 copies/mL, respectively. dscfDNA was higher in recipients with treated biopsy-proven acute rejection (tBPAR) when compared to  ...  ACKNOWLEDGMENTS We acknowledge Boris Wong, Fang Shen, Tom Witkowski, Ashan Musafer, and Ramyar Molania for their technical assistance and the staff of the Liver Transplantation Unit of Victoria and DonateLife  ... 
doi:10.1097/txd.0000000000000902 pmid:31334336 pmcid:PMC6616138 fatcat:2duebaeqgzcr7ievivk6fh2agm

Report on the International Provenance and Annotation Workshop

Rajendra Bose, Ian Foster, Luc Moreau
2006 SIGMOD record  
medical applications, using the example of organ transplant management.  ...  Javier Vazquez-Salceda (Universitat Politecnica De Catalunya) discussed applying the Provenance Aware Service Oriented Architecture (PASOA) and EU Provenance projects to the domain area of distributed  ... 
doi:10.1145/1168092.1168102 fatcat:l6cgygk2bfc6zdq5ymoo2rvjce

Current State of the Diagnosis of Invasive Pulmonary Aspergillosis in Lung Transplantation

Sabina Herrera, Shahid Husain
2019 Frontiers in Microbiology  
In this review we will navigate through the myriad of diagnostic tests currently available and how they apply to this unique patient population, as well as have a look into what the future holds.  ...  Lung transplantation remains a unique clinical scenario, where additional host defenses are immunocompromized, making many of the available tests unsuitable.  ...  Moreover, diagnostic tests used in other patient populations such as hematological malignancies cannot be readily applied in Lung transplant recipients (LTRs).  ... 
doi:10.3389/fmicb.2018.03273 pmid:30687264 pmcid:PMC6333628 fatcat:4zslgrpjm5bsbkrzwmy4gwxqnu

The Genetic Component of Seagrass Restoration: What We Know and the Way Forwards

Jessica Pazzaglia, Hung Manh Nguyen, Alex Santillán-Sarmiento, Miriam Ruocco, Emanuela Dattolo, Lázaro Marín-Guirao, Gabriele Procaccini
2021 Water  
Also, we discussed different transplantation strategies applied in seagrasses and emphasized the importance of long-term seagrass monitoring in restoration.  ...  Despite the proven importance of genetic research to perform successful restoration projects, this aspect has often been overlooked in seagrass restoration.  ...  conditions as projected in the near future for the transplantation site, i.e., climate-adjusted provenance ( Figure 2 , red line) [88] .  ... 
doi:10.3390/w13060829 fatcat:rrwxnjyhpfelpkj5gqo4hlxhxm
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