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Application of RotaSVM for HLA Class II Protein-Peptide Interaction Prediction

Shib Sankar Bhowmick, Indrajit Saha, Giovanni Mazzocco, Ujjwal Maulik, Luís Rato, Debotosh Bhattacharjee, Dariusz Plewczynski
2014 Proceedings of the International Conference on Bioinformatics Models, Methods and Algorithms  
In this article, the recently developed RotaSVM is used for accurate prediction of binding peptides to Human Leukocyte Antigens class II (HLA class II) proteins.  ...  The understanding of HLA class II protein-peptide binding interaction facilitates the design of peptide-based vaccine, where the high rate of polymorphisms in HLA class II molecules poses a big challenge  ...  with Potential for Excellence (UPE)-Phase II project grant from University Grants Commission (UGC) in India.  ... 
doi:10.5220/0004804801780185 dblp:conf/biostec/BhowmickSMMRBP14 fatcat:cmqwusv2lbd4louqr5ga7rpnxy