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Conventional and point-of-care diagnostic tools for dengue virus detection and their possible treatments

2021 Zenodo  
In the event of a repeat or future DENV outbreak, suggestions for enhanced diagnostic tool utilization have also been discussed.  ...  The last but not the least, a comprehensive summary of numerous old and recently developed therapeutics has been provided so that the researchers and clinicians may devise appropriate strategies for the  ...  Acknowledgement The authors are thankful to Shqra University Saudi Arabia and Isthmus Research and Publishing House, New Delhi, India, for allowing their various resources.  ... 
doi:10.5281/zenodo.5700510 fatcat:mjdoee3hhfbwpg4heavjuamyrq

Advancement of Metatranscriptomics towards Productive Agriculture and Sustainable Environment: A Review

Siti Suhailah Sharuddin, Norhayati Ramli, Mohd Zulkhairi Mohd Yusoff, Nor Azlan Nor Muhammad, Li Sim Ho, Toshinari Maeda
2022 International Journal of Molecular Sciences  
In addressing this matter, the use of environmental microbiomes has been greatly favoured as a 'greener' alternative to these inorganic chemicals' application.  ...  Next, the current environmental metatranscriptomics studies are reviewed, with the discussion centred on (2) the emerging application of the beneficial microbiomes in developing fertile soils and (3) the  ...  To apply this technology in environmental biomonitoring, the specific gene target must be identified before designing the genosensors [119] .  ... 
doi:10.3390/ijms23073737 pmid:35409097 pmcid:PMC8998989 fatcat:u5gtieh3wffnfkricghe4rrdb4

Development and Applications of Microbial Ecogenomic Indicators for Monitoring Water Quality: Report of a Workshop Assessing the State of the Science, Research Needs and Future Directions

Richard Devereux, Parke Rublee, John H. Paul, Katharine G. Field, Jorge W. Santo Domingo
2006 Environmental Monitoring & Assessment  
Development and applications of microbial ecogenomic indicators for monitoring water quality: Report of a workshop assessing the state of the science, research needs and future directions.  ...  -Develop bioinformatics algorithms for data interpretation of genomic applications in environmental assessments and molecular technologies.  ...  Bioinformatics will be an important component of applications in environmental science. Ecogenomics, the application of genomics to answer environmental questions, is a new science.  ... 
doi:10.1007/s10661-006-7665-7 pmid:16779607 fatcat:6grn5345efatfdwid36z4kgkxq

Molecular and Biotechnological Approaches in the Diagnosis of Leprosy [chapter]

Mayara Ingrid Sousa Lima, Emilly Caroline dos Santos Moraes, Jaqueline Diniz Pinho, Gustavo Henrique Corrêa Soares, Ítalo Vinícius Cantanhêde Santos
2019 Hansen's Disease - The Forgotten and Neglected Disease  
Enzyme-linked immunosorbent assay (ELISA) is the used method for leprosy diagnosis, and it allows the detection of infection-related antigens.  ...  to be used in immunodiagnostic and molecular methods for the detection of Mycobacterium leprae, is an important tool to confirm the clinical diagnostic.  ...  essential for the identification of proteins and peptides with applicability in the laboratory detection of the disease [38] .  ... 
doi:10.5772/intechopen.75506 fatcat:zvh2bt3lqffn5mi3oag2t7p5ku

Nucleic Acid-Based Sensing Techniques for Diagnostics and Surveillance of Influenza

Samantha J. Courtney, Zachary R. Stromberg, Jessica Z. Kubicek-Sutherland
2021 Biosensors  
Nucleic acid-based tests are more accurate than rapid antigen tests for influenza and are therefore better candidates to be used in both diagnostic and surveillance applications.  ...  There has been substantial progress in the development of nucleic acid-based sensing techniques for the detection of influenza virus.  ...  The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.  ... 
doi:10.3390/bios11020047 pmid:33673035 pmcid:PMC7918464 fatcat:3twyheqe3rdppaqv3ewnu6ztr4

Meet the contributors

Nicola Oberbeckmann-Winter
2020 Analytical and Bioanalytical Chemistry  
The Sombers lab is particularly focused on the development of new electroanalytical tools for the real-time monitoring of neurochemicals in systems ranging from subcellular domains to discrete brain regions  ...  She and her research group are developing novel optical spectroscopy instruments for the analysis of plant biomass, mammalian cell membranes, and nanomaterials.  ...  Her current research focuses on the design and selfassembly of functional materials made from engineered proteins for applications in immunology; cancer; and, more recently, biocatalysis.  ... 
doi:10.1007/s00216-020-02829-9 pmid:32767068 fatcat:3o6sqdxawzezrnllbchrxxli3e

Cell-free fetal nucleic acids in amniotic fluid

L. Hui, D.W. Bianchi
2010 Human Reproduction Update  
biological resource.  ...  There is otherwise a paucity of information relating to the basic biology and clinical applications of cff nucleic acids in AF. conclusions: AF supernatant is a valuable and widely available but under-utilized  ...  This feasibility study successfully used cff DNA for CGH microarray analysis with the GenoSensor Array 300.  ... 
doi:10.1093/humupd/dmq049 pmid:20923874 pmcid:PMC3072021 fatcat:iielphluiveupog6lopk3eiqly

The Translational Potential of Electrochemical DNA-Based Liquid Biopsy

Rebeca Miranda-Castro, Ilaria Palchetti, Noemí de-los-Santos-Álvarez
2020 Frontiers in Chemistry  
DNA emerges as a versatile analytical reagent in electrochemical devices for hybridization-based or aptamer-based recognition of all kind of biomarkers.  ...  This review focuses on the hurdles of the complex matrices rather than a comprehensive and detailed revision of the format schemes of DNA-based electrochemical sensing.  ...  The nucleic acid nature of capturing aptamers provides an easy way of recovering intact CTCs or exosomes for downstream applications .  ... 
doi:10.3389/fchem.2020.00143 pmid:32266206 pmcid:PMC7099045 fatcat:dln4iq4unvb2jfswzwmotndb7a

miRNA-based biomarkers, therapies, and resistance in Cancer

Boxue He, Zhenyu Zhao, Qidong Cai, Yuqian Zhang, Pengfei Zhang, Shuai Shi, Hui Xie, Xiong Peng, Wei Yin, Yongguang Tao, Xiang Wang
2020 International Journal of Biological Sciences  
Based on evidence about miRNA, numerous potential cancer biomarkers for the diagnosis and prognosis have been put forward, providing a new perspective on cancer screening.  ...  A variety of miRNAs could take roles in the cancer progression, participate in the process of tumor immune, and function with miRNA sponges.  ...  All of the protocols were reviewed and approved by the Joint Ethics Committee of the Central South University Health Authority and performed in accordance with national guidelines.  ... 
doi:10.7150/ijbs.47203 pmid:32792861 pmcid:PMC7415433 fatcat:ooqcwa6hyzhrzomp4jcvasjqdm

Towards detection and diagnosis of Ebola virus disease at point-of-care

Ajeet Kaushik, Sneham Tiwari, Rahul Dev Jayant, Aileen Marty, Madhavan Nair
2016 Biosensors & bioelectronics  
This review highlights SoA of Ebola diagnostics and also a call to develop rapid, selective and sensitive POC detection of EBOV for global health care.  ...  World Health Organization (WHO) has declared EVD epidemic as public health emergency of international concern with severe global economic burden.  ...  The Public Health & Security Interface (HSI) of the Global Outbreak Alert and Response Network (GOARN), WHO and NSF-AIR IIP-1237818 "PFI-AIR: CREST-I/UCRC-Industry Ecosystem to Pipeline Research" are also  ... 
doi:10.1016/j.bios.2015.08.040 pmid:26319169 pmcid:PMC4601610 fatcat:4fiqw66ehbca3hntowywy2gdwy

Alterations in CDH15 and KIRREL3 in Patients with Mild to Severe Intellectual Disability

Kavita Bhalla, Yue Luo, Tim Buchan, Michael A. Beachem, Gregory F. Guzauskas, Sydney Ladd, Shelly J. Bratcher, Richard J. Schroer, Janne Balsamo, Barbara R. DuPont, Jack Lilien, Anand K. Srivastava
2008 American Journal of Human Genetics  
We screened coding regions of these two genes in a cohort of patients with ID and controls and identified four nonsynonymous CDH15 variants and three nonsynonymous KIRREL3 variants that appear rare and  ...  Furthermore, in vivo expression studies showed that three of the CDH15 variations adversely altered its ability to mediate cell-cell adhesion.  ...  The American Journal of Human Genetics 83, 703-713, December 12, 2008 711 and K.B. Clarkson for providing clinical details of patients; D. Bealer and C.  ... 
doi:10.1016/j.ajhg.2008.10.020 pmid:19012874 pmcid:PMC2668064 fatcat:u6e7bas2krb6lbib6waz6bmi4i

Crystal ball - 2009

2009 Environmental Microbiology Reports  
The essence of this Crystal ball 17  ...  Hence, it could be a very useful tool in environmental microbiology, which deals with an enormous number and diversity of unknown populations, processes and habitats, many of which escape human scales,  ...  Acknowledgements We would like to extend special thanks to the Agouron Institute, the C-MORE, and the School of Ocean and Earth Science at the University of Hawaii at Mā noa.  ... 
doi:10.1111/j.1758-2229.2008.00010.x pmid:23765716 fatcat:a2h7akkx5zg7pntlrwpwjj6rh4

Report from the 1st MYCOKEY International Conference Global Mycotoxin Reduction in the Food and Feed Chain Held in Ghent, Belgium, 11–14 September 2017

Sarah De Saeger, Antonio Logrieco
2017 Toxins  
Acknowledgments: Projects JIUZ-2014-CIE-05 (University of Zaragoza); Grupo Consolidado A01  ...  We have developed optical genosensors for the detection of closely related species F. verticillioides and F. proliferatum based on species-specific oligonucleotide probes designed for the intergenic spacer  ...  Abstract: The increasing availability of fungal genomes and bioinformatic tools have led to the identification of clusters of known metabolites and to the prediction of novel cryptic clusters for still  ... 
doi:10.3390/toxins9090276 pmid:28885598 pmcid:PMC5618209 fatcat:nfgu6vsacjdm3lm3biu4retsa4

Simposio de Química Aplicada (SIQUIA)

Varios Autores
2019 Revista de Investigaciones Universidad del Quindío  
Brabec from i-MEET at Friedrich Alexander Universität (FAU) of Erlangen -Nürnberg, Germany.  ...  The production of affordable YBa2Cu3O7-δ (YBCO) coated conductors (CC), for industrial applications, is an extremely challenging issue.  ...  Those results are very promising for application in environmental and public health problem caused by use of mercury in illegal gold mining.  ... 
doi:10.33975/riuq.vol31nsuplemento.273 fatcat:75ez2c7w5fedtiyddu7sska5hm


Jan Bojkovski, Uzuner, Kinik, Korel, Yildız, Yerlikaya, Aydin Uzuner, Ozer Kinik, Figen Korel, Gamze Yildız, Oktay Yerlikaya
Physical, rheological and sensory properties of non-alcoholic malt beverage formulated with date syrup 47-56 Sumonsiri Nutsuda, Effect of nisin on qualities of pork meatballs during refrigerated storage  ...  ., Immobilization of probiotic bacteria with banana flour and effect on quality of synbiotic ice cream and survival under simulated gastrointestinal conditions 33-46 Hajieghrary F., Homayouni-Rad A., ,  ...  The authors would like to thank to "Izmir Institute of Technology, Environmental Development, Application and Research Center" for GC-MS analysis.  ...