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Vacuum brazing of carbon nanotube bundles
2008
Materials letters (General ed.)
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We have investigated vacuum brazing of CNTs with a eutectic alloy (Ag x Cu y ) doped with Ti. Bonding is confirmed to involve formation of covalent bonds between Ti and C atoms. The brazing in vacuum leads to the interdiffusion of Ti and C atoms and reaction at the joining interfaces. This joining process is promising for volume production with low cost and a low contact resistance.
doi:10.1016/j.matlet.2008.08.020
fatcat:vuonvtzlmnh6dpo2qhhfc36pbm
Comments on the APG's classification of angiosperms
2017
Biodiversity Science
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With the rise of plant molecular systematics, tremendous progress has been made in understanding phylogenetic relationships within angiosperms. With the basic phylogenetic framework of angiosperms established, a DNA phylogeny-based angiosperm classification system at the order and familial levels was proposed by the Angiosperm Phylogeny Group (APG) in 1998 and has been updated three times. In this paper, we summarize the major achievements of the APG system as follows: (1) testing the
doi:10.17520/biods.2017015
fatcat:6uonzzh7evfqjc7sdlqlj55z2a
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... ity and predictability of the APG system for angiosperms; (2) resolving the systematic positions of some segregate taxa which were not placed based on morphological characters; (3) proving that it is not reasonable to first divide angiosperms based on cotyledon character; (4) demonstrating the importance of tricolpate/tricolporate pollen and derivatives for angiosperm classification; (5) finding that the centrifugal development of stamens in polyandrous groups have evolved independently many times and should not be used to delimit class or subclass of angiosperms; (6) supporting that most of the families delimited by broad morphological characters are natural; and (7) separating some families which are traditionally regarded as natural. We then point out potential problems that need to be resolved in the future, including: (1) how to harmonize the APG system and the morphology-based systems; (2) establishing new morphological evolution theories on the basis of the APG system; (3) determining whether it is enough to only use "monophyly" as a criterion to circumscribe orders and families; (4) determining morphological synapormorphies of those orders in the APG sys- tem; and (5) how to best compile a key to distinguish the orders and families of the APG system and to list their diagnostic characters for orders and families. In addition, we propose suggestions for the phylogenetic relationships and taxonomic status of some taxa mainly distributed in Asia, specifically East Asia, including Illiciaceae, Acanthochlamydaceae, Tetracentraceae, Leeaceae, Rhoipteiaceae, Hippocastenaceae, Aceraceae, Bretschneideraceae as familial status, and dividing Cornaceae sensu lato into Cornaceae sensu stricto and Nyssaceae sensu lato.
A new method for isomorphism identification of planetary gear trains
2021
Mechanical Sciences
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This paper was edited by Guowu Wei and reviewed by two anonymous referees. ...
doi:10.5194/ms-12-193-2021
fatcat:e5ahq2uw7jeohc2n2ocrqpw5cm
Weathering of Roofing Insulation Materials under Multi-Field Coupling Conditions
2019
Materials
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Rigid polyurethane foam, foam concrete, and vacuum insulation board are common roofing insulation materials. Their weathering performance under long-term multi-field coupling determines the overall service life of the roof. The weathering properties of rigid polyurethane foam, foam concrete and vacuum insulation panels were studied under freeze thaw, humid-heat, dry-wet, high-low temperature, and multi-field coupling cycles, respectively. The heat transfer and construction process of roof
doi:10.3390/ma12203348
pmid:31615085
pmcid:PMC6829217
fatcat:s3kl6z7ob5fpnpkm2onxka5d7y
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... was simulated base on upper loading and moisture transfer factors. The result indicates that the mass loss of the foam concrete and the rigid polyurethane foam in the weathering test was significant, which led to the gradual increase of thermal conductivity. Meanwhile, the thermal conductivity and mass loss of vacuum insulation panels did not change due to the lack of penetration under external pressure, therefore, it is necessary to construct composite thermal–insulation materials to alleviate the adverse effects of the service environment on a single material and realize the complementary advantages and disadvantages of the two materials. The results of the numerical simulations indicated that the roof structure must be waterproofed, and its weatherproof performance index should be the same as that of the thermal insulation material. Considering structural deformation, the overall heat transfer performance of the product was increased by around 5%.
Evaluation and characterization of the predicted diguanylate cyclase-encoding genes in Pseudomonas aeruginosa
2020
MicrobiologyOpen
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Pramod Bhasme: Investigation, writing-original draft, writing-review & editing; Qing Wei: Investigation, writing-original draft, writingreview & editing; Anming Xu: Formal analysis, methodology, writing-review ...
of extracellular polymeric substances including exopolysaccharides, extracellular DNA, and proteins (Decho & Gutierrez, 2017; Fong & Yildiz, 2015; Koo, Allan, Howlin, Stoodley, & Hall-Stoodley, 2017; Wei ...
doi:10.1002/mbo3.975
pmid:32012489
fatcat:m2j4ggsokfg6fk2rgvoqvxprda
Simulation of groundwater table dynamics based on Feflow in the Minqin Basin, China
2012
Journal of Arid Land
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et al., 2005; Ma and Wei, 2006; Sun et al., 2009) . ...
Groundwater flows from southwest to northeast with a hydraulic gradient of 0.3%-0.07% and decreasing runoff intensity (Ma and Wei, 2003) . ...
doi:10.3724/sp.j.1227.2012.00123
fatcat:rilfmv4kgzhibbku3we36qpowy
Evidence for neural re-use hypothesis from the processing of Chinese emotional words
2021
Acta Psychologica Sinica
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Single-stage operation for traumatic thoracolumbar fractures with severe dislocation via a posterior approach alone: a case series
2012
Turkish Neurosurgery
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AIm: This study reports a technique for treating severe thoracolumbar fractures with single-stage decompression, reduction, reconstruction, and stabilization via an entirely posterior approach. mAterIAl and methOds: The cases of 11 patients with severe traumatic thoracolumbar fractures/dislocations that were managed with single-stage decompression, reduction, reconstruction, and stabilization via an entirely posterior approach were included. Data on age, sex, mechanism of injury, associated
doi:10.5137/1019-5149.jtn.5782-12.2
pmid:23546901
fatcat:b4gtdoijuveh7kezehppakusi4
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... ma, neurological status, surgical technique, and clinical outcome were reviewed retrospectively. results: Of the 11 patients, two presented with primarily coronal displacement and nine with sagittal displacement. Coronal displacement was corrected from 19% preoperatively to 4.0% at the last follow-up evaluation. Sagittal displacement was reduced from 73.0% preoperatively to 3.0% at the last follow-up evaluation. After a mean follow-up period of 20.7 (range 16-30) months, no patient complained of local pain and no significant loss of correction or hardware failure was observed. COnClusIOn: Our experience proves that the single-stage posterior approach is safe and biomechanically reliable for treating severe thoracolumbar fractures/dislocations. Therefore, the presented technique is an alternative approach for this rare injury. ÖZ AmAÇ: Bu çalışma, tamamen posterior bir yaklaşımla tek evreli dekompresyon, redüksiyon, rekonstrüksiyon ve stabilizasyon ile şiddetli torakolumber kırıkları tedavi etmek için bir tekniği bildirmektedir. yÖntem ve GereÇler: Tamamen posterior yaklaşımla tek evreli dekompresyon, redüksiyon, rekonstrüksiyon ve stabilizasyonla tedavi edilen şiddetli travmatik torakolumber kırık/dislokasyonu olan 11 vaka dahil edilmiştir. Yaş, cinsiyet, yaralanma mekanizması, ilgili travma, nörolojik durum, cerrahi teknik ve klinik sonuçlarla ilgili veriler retrospektif olarak gözden geçirilmiştir. BulGulAr: 11 hasta içinde ikisi primer koronal displasman ve dokuzu sajital displasmanla gelmiştir. Sajital displasman preoperatif olarak %19'dan son takip değerlendirmesinde %4,0'a düzeltilmiştir. Sajital displasman preoperatif olarak %73,0'dan son takip değerlendirmesinde %3,0'a düzeltilmiştir. Ortalama 20,7 (aralık 16-30) aylık takip süresiyle hiçbir hasta yerel ağrıdan yakınmamış ve düzeltmede önemli bir kayıp veya donanımla ilgili başarısızlık gözlenmemiştir. sOnuÇ: Deneyimimiz tek evreli posterior yaklaşımın şiddetli torakolumber kırıklar/dislokasyonlar tedavisinde güvenli ve biyomekanik olarak uyumlu olduğunu göstermiştir. Bu nedenle sunulan teknik bu nadir yaralanma için alternatif bir yaklaşımdır.
Integrated Comparative Genomic Analysis and Phenotypic Profiling of Pseudomonas aeruginosa Isolates From Crude Oil
2020
Frontiers in Microbiology
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Pseudomonas aeruginosa is an environmental microorganism that can thrive in diverse ecological niches including plants, animals, water, soil, and crude oil. It also one of the microorganism widely used in tertiary recovery of crude oil and bioremediation. However, the genomic information regarding the mechanisms of survival and adapation of this bacterium in crude oil is still limited. In this study, three Pseudomonads strains (named as IMP66, IMP67, and IMP68) isolated from crude oil were
doi:10.3389/fmicb.2020.00519
pmid:32300337
pmcid:PMC7145413
fatcat:qbyqnhdd2namxobfrmf6tetjte
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... for whole-genome sequencing by using a hybridized PacBio and Illumina approach. The phylogeny analysis showed that the three strains were all P. aeruginosa species and clustered in clade 1, the group with PAO1 as a representitive. Subsequent comparative genomic analysis revealed a high degree of individual genomic plasticity, with a probable alkane degradation genomic island, one type I-F CRISPR-Cas system and several prophages integrated into their genomes. Nine genes encoding alkane hydroxylases (AHs) homologs were found in each strain, which might enable these strains to degrade alkane in crude oil. P. aeruginosa can produce rhamnolipids (RLs) biosurfactant to emulsify oil, which enables their survival in crude oil enviroments. Our previous report showed that IMP67 and IMP68 were high RLs producers, while IMP66 produced little RLs. Genomic analysis suggested that their RLs yield was not likely due to differences at genetic level. We then further analyzed the quorum sensing (QS) signal molecules that regulate RLs synthesis. IMP67 and IMP68 produced more N-acyl-homoserine lactones (AHLs) signal molecules than that of PAO1 and IMP66, which could explain their high RLs yield. This study provides evidence for adaptation of P. aeruginosa in crude oil and proposes the potential application of IMP67 and IMP68 in microbial-enhanced oil recovery and bioremediation.
A VTA GABAergic neural circuit mediates visually evoked innate defensive responses
[article]
2018
bioRxiv
pre-print
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511 direction. 512 Our previous study demonstrated that glutamatergic neurons in mILSC projected to 513 an LP-LA circuit mediating looming-evoked freezing behavior in an open-field without 514 nest (Wei ...
doi:10.1101/493007
fatcat:lujrk4mcubegjkdnlf5tawtmk4
miR‑224/miR‑141 ratio as a novel diagnostic biomarker in renal cell carcinoma
2018
Oncology Letters
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Biomarkers to guide the clinical treatment of patients with renal cell carcinoma (RCC) are not yet routinely available. MicroRNAs (miRNAs) have been demonstrated to serve as biomarkers for a number of types of cancer. Based on a previous study by this group, we hypothesize that several highly differentially expressed miRNAs may serve as tissue and plasma biomarkers in patients with RCC. The expression levels of miR-210, miR-224 and miR-141 were analyzed in tissue samples from the same cohort of
doi:10.3892/ol.2018.8874
pmid:30008851
pmcid:PMC6036413
fatcat:clakkplpjfgtvbexkjcpgsxtiu
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... 78 patients with RCC, in paired pre-and post-operative plasma samples from 66 patients with clear cell RCC (ccRCC) and in 67 healthy controls by reverse transcription-quantitative polymerase chain reaction. Receiver operating characteristic (ROC) was used to evaluate the diagnostic accuracy associated with the expression of miR-210, miR-224 and miR-141. ROC curves revealed that the diagnostic accuracy (area under the curve) of tissue miR-210, miR-224, the ratio of miR-210/miR-141 (miR 210/141 ), miR-224/miR-141 (miR 224/141 ) and miR-210x miR-224/miR-141 (miR 210x224/141 ) in ccRCC was 0.8329, 0.8511, 0.9412, 0.9898 and 0.9771, respectively. Notably, miR 224/141 demonstrated the highest accuracy among these miRNAs for discriminating ccRCC tissues from normal tissues, with a sensitivity of 97.06% and a specificity of 98.53%. The expression levels of plasma miR-210 and miR-224 were significantly increased in patients compared with healthy control patients, and were reduced postoperatively (P<0.05). The diagnostic accuracy of plasma miR-210 and miR-224 were 0.6775 (89.55% sensitivity and 48.48% specificity) and 0.6056 (88.06% sensitivity and 40.91% specificity), respectively. The present study indicated that the tissue miR-224/miR-141 ratio is a potentially powerful tool for detecting ccRCC. However, plasma miR-210 and miR-224 may not be associated with diagnosis of ccRCC.
Protein Phosphatase 4 Cooperates with Smads to Promote BMP Signaling in Dorsoventral Patterning of Zebrafish Embryos
2012
Developmental Cell
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BMP signals play pivotal roles in dorsoventral patterning of vertebrate embryos. The role of Ppp4c, the catalytic subunit of ubiquitous protein phosphatase 4, in vertebrate embryonic development and underlying mechanisms is poorly understood. Here, we demonstrate that knockdown of zebrafish ppp4cb and/or ppp4ca inhibits ventral development in embryos and also blocks ventralizing activity of ectopic Smad5. Biochemical analyses reveal that Ppp4c is a direct binding partner and transcriptional
doi:10.1016/j.devcel.2012.03.001
pmid:22595677
fatcat:p2x2cinyb5echm4hbuaf3eia2e
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... tivator of Smad1/Smad5. In response to BMP, Ppp4c is recruited to the Smad1-occupied promoter, and its phosphatase activity is essential in inhibiting HDAC3 activity and, consequently, potentiating transcriptional activation. Consistently, genetic or chemical interference of Hdac3 expression or activity compromises the dorsalizing phenotype induced by ppp4cb knockdown. We conclude that Ppp4c is a critical positive regulator of BMP/Smad signaling during embryonic dorsoventral pattern formation in zebrafish.
Systemic phylogenetic and transcriptomic analyses reveal diguanylate cyclases and phosphodiesterases required for the basal level of c-di-GMP in Pseudomonas aeruginosa
2019
Applied and Environmental Microbiology
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Cyclic diguanosine monophosphate (c-di-GMP) is an important second messenger involved in bacterial switching from motile to sessile lifestyles. In the opportunistic pathogen Pseudomonas aeruginosa, at least 40 genes are predicted to encode proteins for the making and breaking of this signal molecule. However, there is still paucity of information concerning the systemic expression pattern of those genes and the functions of uncharacterized genes. In this study, we analyzed the phylogenetic
doi:10.1128/aem.01194-19
pmid:31444209
pmcid:PMC6803301
fatcat:a7ore42fsvc6nnj7x377oap2ki
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... ibution of genes from P. aeruginosa that predicted to have a GGDEF domain and found five genes (PA5487, PA0285, PA0290, PA4367 and PA5017) with highly conserved distribution across 52 public complete Pseudomonads genomes. PA5487 was further characterized as a typical diguanylate cyclase (DGC) and was named dgcH. A systemic analysis of the gene expression data revealed that the expression of dgcH is highly invariable and dgcH probably functions as a conserved gene to maintain the basal level of c-di-GMP, as reinforced by gene expression analyses. The other four conserved genes also had similar expression pattern as dgcH. The functional analysis suggested that PA0290 encoded a DGC while the others functioned as phosphodiesterases (PDE). Our data revealed that there are five DGC and PDE genes that maintain the basal level of c-di-GMP in P. aeruginosa. Importance Pseudomonas aeruginosa is an opportunistic pathogen that can cause infections in animals, humans and plants. The formation of biofilms by P. aeruginosa is the central mode of action to persist in hosts and evade immune and antibiotic attacks. Cyclic-di-GMP (c-di-GMP) is an important second messenger involved in the regulation of biofilm formation. In P. aeruginosa PAO1 strain, there are around 40 genes that encode enzymes for the making and breaking this dinucleotide. A major missing information in this field is the phylogeny and expression profile of those genes. Here we took a systemic approach to investigate this mystery. We found that among 40 c-di-GMP metabolizing genes, five of them have well conserved phylogenetic distribution and invariable expression profiles, suggesting there are enzymes required for the basal level of c-di-GMP in P. aeruginosa. This study would thus provide putative therapeutic targets against P. aeruginosa infections.
Progress and prospects of applied research on physical geography and the living environment in China over the past 70 years (1949–2019)
2021
Journal of Geographical Sciences
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Cheng Guodong and Ma Wei were selected as foreign fellows by the Russian Academy of Engineering. ...
doi:10.1007/s11442-021-1831-2
fatcat:yxjilrfxpranxln4vh6bt5wahm
Protein Encoded by theAxinFuAllele Effectively Down-regulates Wnt Signaling but Exerts a Dominant Negative Effect on c-Jun N-terminal Kinase Signaling
2008
Journal of Biological Chemistry
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Axin plays an architectural role in many important signaling pathways that control various aspects of development and tumorigenesis, including the Wnt, transforming growth factor-, MAP kinase pathways, as well as p53 activation cascades. It is encoded by the mouse Fused (Fu) locus; the Axin Fu allele is caused by insertion of an IAP transposon. Axin Fu/Fu mice display varying phenotypes ranging from embryonic lethality to relatively normal adulthood with kinky tails. However, the protein
doi:10.1074/jbc.m710595200
pmid:18316368
fatcat:z7z4bx5vk5dhdkvvmnr2sa7qz4
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... t(s) has not been identified or characterized. In the present study, we conducted immunoprecipitation using brain extracts from the Axin Fu mice with specific antibodies against different regions of Axin and found that a truncated Axin containing amino acids 1-596 (designated as Axin Fu-NT ) and the full-length complement of Axin (Axin WT ) can both be generated from the Axin Fu allele. When tested for functionality changes, Axin Fu-NT was found to abolish Axin-mediated activation of JNK, which plays a critical role in dorsoventral patterning. Together with a proteomics approach, we found that Axin Fu-NT contains a previously uncharacterized dimerization domain and can form a heterodimeric interaction with Axin WT . The Axin Fu-NT / Axin WT is not conducive to JNK activation, providing a molecular explanation for the dominant negative effect of Axin Fu-NT on JNK activation by wild-type Axin. Importantly, Axin Fu-NT exhibits no difference in the inhibition of Wnt signaling compared with Axin WT as determined by reporter gene assays, interaction with key Wnt regulators, and expression of Wnt marker genes in zebrafish embryos, suggesting that altered JNK signaling contributes, at least in part, to the developmental defects seen in Axin Fu mice.
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