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Text/Conference Paper

Anja Hawlitschek, André Dietrich, Sebastian Zug
2019 Fachtagung "e-Learning" der Gesellschaft für Informatik  
Zeitschrift für Pädagogische Psychologie, 23(2), 105-115, 2009. 336 Anja Hawlitschek et al. Lernenden auf relevante Fakten, Prozeduren und Ansätze aufmerksam machen sollen [Th09].  ... 
doi:10.18420/delfi2019_342 dblp:conf/delfi/HawlitschekDZ19 fatcat:nr6fifkusrhgdghxlanqv4d2cy

Le long chemin d'une charte vers l'ère multimédiale [chapter]

Martin-Dietrich Gleßgen, Anja Overbeck, Wolfgang Schweickard, Harald Völker
2011 Lexikon, Varietät, Philologie  
doi:10.1515/9783110262292.649 fatcat:c225uxmfvrggvl3c27b4ozke3u

Early rectal stenosis following stapled rectal mucosectomy for hemorrhoids

Sven Petersen, Gunter Hellmich, Dietrich Schumann, Anja Schuster, Klaus Ludwig
2004 BMC Surgery  
Within the last years, stapled rectal mucosectomy (SRM) has become a widely accepted procedure for second and third degree hemorrhoids. One of the delayed complications is a stenosis of the lower rectum. In order to evaluate the specific problem of rectal stenosis following SRM we reviewed our data with special respect to potential predictive factors or stenotic events. Methods: A retrospective analysis of 419 consecutive patients, which underwent SRM from December 1998 to August 2003 was
more » ... med. Only patients with at least one follow-up check were evaluated, thus the analysis includes 289 patients with a mean follow-up of 281 days (±18 days). For statistic analysis the groups with and without stenosis were evaluated using the Chi-Square Test, using the Kaplan-Meier statistic the actuarial incidence for rectal stenosis was plotted. Results: Rectal stenosis was observed in 9 patients (3.1%), eight of these stenoses were detected within the first 100 days after surgery; the median time to stenosis was 95 days. Only one patient had a rectal stenosis after more than one year. 8 of the 9 patients had no obstructive symptoms, however the remaining patients complained of obstructive defecation and underwent surgery for transanal strictureplasty with electrocautery. A statistical analysis revealed that patients with stenosis had significantly more often prior treatment for hemorrhoids (p < 0.01). According to the SRM only severe postoperative pain was significantly associated with stenoses (p < 0.01). Other factors, such as gender (p = 0.11), surgical technique (p = 0.25), revision (p = 0.79) or histological evidence of squamous skin (p = 0.69) showed no significance. Conclusion: Rectal stenosis is an uncommon event after SRM. Early stenosis will occur within the first three months after surgery. The majority of the stenoses are without clinical relevance. Only one of nine patients had to undergo surgery for a relevant stenosis. The predictive factor for stenosis in the patient-characteristics is previous interventions for hemorrhoids, severe postoperative pain might also predict rectal stenosis.
doi:10.1186/1471-2482-4-6 pmid:15153248 pmcid:PMC420246 fatcat:h3fmyh6wdvenvp3ahlnscqkpuu

Compensatory versus noncompensatory models for predicting consumer preferences

Anja Dieckmann, Katrin Dippold, Holger Dietrich
2009 Judgment and Decision Making  
and estimated responses r i is minimal. 1 More elaborate methods that ask for self-explicated attribute preferences such as ACA (Johnson, 1987; Green, Krieger & Agarwal, 1991) and HILCA (Wildner, Dietrich  ... 
doaj:32567cc327604660bceb0c46ad2b35c3 fatcat:zukiwf5cgnhc5nc3fwaruevqzi

Tidal gravity variations revisited at Vostok Station, Antarctica

Koichiro Doi, Kazuo Shibuya, Anja Wendt, Reinhard Dietrich, Matt King
2009 Polar Science  
., 1996) ; indeed, Dietrich et al. (2001) attributed these discrepancies to the effect of tides in Lake Vostok.  ... 
doi:10.1016/j.polar.2008.11.001 fatcat:ecmmug6gprejhi2y52ll2duekm

Ein national gefördertes Onlinelabor als Infrastruktur für die psychologische Forschung

Martin Bruder, Anja S. Göritz, Ulf-Dietrich Reips, Ramon K. Gebhard
2014 Psychologische Rundschau  
Standard-Nutzungsbedingungen: Die Dokumente auf EconStor dürfen zu eigenen wissenschaftlichen Zwecken und zum Privatgebrauch gespeichert und kopiert werden. Sie dürfen die Dokumente nicht für öffentliche oder kommerzielle Zwecke vervielfältigen, öffentlich ausstellen, öffentlich zugänglich machen, vertreiben oder anderweitig nutzen. Sofern die Verfasser die Dokumente unter Open-Content-Lizenzen (insbesondere CC-Lizenzen) zur Verfügung gestellt haben sollten, gelten abweichend von diesen
more » ... bedingungen die in der dort genannten Lizenz gewährten Nutzungsrechte. Die RatSWD Working Papers Reihe startete Ende 2007. Seit 2009 werden in dieser Publikationsreihe nur noch konzeptionelle und historische Arbeiten, die sich mit der Gestaltung der statistischen Infrastruktur und der Forschungsinfrastruktur in den Sozial-, Verhaltens-und Wirtschaftswissenschaften beschäftigen, publiziert. Dies sind insbesondere Papiere zur Gestaltung der Amtlichen Statistik, der Ressortforschung und der akademisch getragenen Forschungsinfrastruktur sowie Beiträge, die Arbeit des RatSWD selbst betreffend. Auch Papiere, die sich auf die oben genannten Bereiche außerhalb Deutschlands und auf supranationale Aspekte beziehen, sind besonders willkommen. RatSWD Working Papers sind nicht-exklusiv, d. h. einer Veröffentlichung an anderen Orten steht nichts im Wege. Alle Arbeiten können und sollen auch in fachlich, institutionell und örtlich spezialisierten Reihen erscheinen. Die RatSWD Working Papers können nicht über den Buchhandel, sondern nur online über den RatSWD bezogen werden. Um nicht deutsch sprechenden Nutzer/innen die Arbeit mit der Reihe zu erleichtern, sind auf den englischen Internetseiten der RatSWD Working Papers nur die englischsprachigen Papers zu finden, auf den deutschen Seiten werden alle Nummern der Reihe chronologisch geordnet aufgelistet. Einige ursprünglich in der RatSWD Working Papers Reihe erschienenen empirischen Forschungsarbeiten sind ab 2009 in der RatSWD Research Notes Reihe zu finden. Die Inhalte der RatSWD Working Papers stellen ausdrücklich die Meinung der jeweiligen Autor/innen dar und nicht die des RatSWD. Das Bundesministerium für Bildung und Forschung hat die Publikationen nicht beeinflusst. Herausgeber der RatSWD Working Paper Series: Vorsitzender des RatSWD Zusammenfassung Momentan besteht hohes wissenschaftspolitisches Interesse an der Entwicklung von Forschungsinfrastrukturen in allen Wissenschaftsbereichen. Wir plädieren dafür, ein national gefördertes Onlinelabor für die psychologische Forschung in diesen Diskurs einzubringen. Dieses Labor sollte einen großen Teilnehmerpool, notwendige Software-Tools, edukative Komponenten (Methodenberatung) sowie Schnittstellen zu Datenarchiven zur Verfügung stellen. Die Vorteile einer solchen Einrichtung werden auf der Basis von Effizienzbetrachtungen sowie methodischen und forschungsethischen Überlegungen verdeutlicht. Abschließend diskutieren wir mittelfristige Entwicklungspotenziale eines Nationalen Onlinelabors. Abstract A nationally funded online laboratory as infrastructure for psychological research There currently is a high level of science policy interest in the development of research infrastructures in all scientific areas. We propose to promote the idea of a national online laboratory within this discourse. This laboratory should provide access to a large participant pool, should offer software tools, provide education on Internet-based research methodologies, and should interface with data archives. We spell out the advantages of such a facility on the basis of efficiency concerns as well as considerations concerning research methodology and research ethics. We conclude with a discussion of mid-term developmental potentials of a nationally funded online laboratory.
doi:10.1026/0033-3042/a000198 fatcat:ftuc62mea5gkjdeyw2t3gy4jmi

Vertical partitioning of CO2 production in a Dystric Cambisol

Patrick Wordell-Dietrich, Axel Don, Anja Wotte, Janet Rethemeyer, Jörg Bachmann, Mirjam Helfrich, Kristina Kirfel, Christoph Leuschner
2019 Biogeosciences Discussions  
., 2010; Wordell-Dietrich et al., 2017) , suggesting that subsoils also contain a labile fraction that should be taken 15 into account as a source for soil respiration.  ... 
doi:10.5194/bg-2019-143 fatcat:4wmvoecxdvac5bfviocv7pohle

The Delta Subunit of Rod-Specific Photoreceptor cGMP Phosphodiesterase (PDE6D) Contributes to Hepatocellular Carcinoma Progression

Peter Dietrich, Claus Hellerbrand, Anja Bosserhoff
2019 Cancers  
Emerging evidence reveals crucial roles of wild type RAS in liver cancer. The delta subunit of rod-specific photoreceptor cGMP phosphodiesterase (PDE6D) regulates the trafficking of RAS proteins to the plasma membrane and thereby contributes to RAS activation. However, the expression and specific function of PDE6D in hepatocellular carcinoma (HCC) were completely unknown. In this study, PDE6D was newly found to be markedly upregulated in HCC tissues and cell lines. Overexpression of PDE6D in
more » ... correlated with enhanced tumor stages, tumor grading, and ERK activation. PDE6D depletion significantly reduced proliferation, clonogenicity, and migration of HCC cells. Moreover, PDE6D was induced by TGF-β1, the mediator of stemness, epithelial-mesenchymal transition (EMT), and chemoresistance. In non-resistant cells, overexpression of PDE6D conferred resistance to sorafenib-induced toxicity. Further, PDE6D was overexpressed in sorafenib resistance, and inhibition of PDE6D reduced proliferation and migration in sorafenib-resistant HCC cells. Together, PDE6D was found to be overexpressed in liver cancer and correlated with tumor stages, grading, and ERK activation. Moreover, PDE6D contributed to migration, proliferation, and sorafenib resistance in HCC cells, therefore representing a potential novel therapeutic target.
doi:10.3390/cancers11030398 pmid:30901922 pmcid:PMC6468542 fatcat:n5wdgtij4vbs5p3lr2kc6fopxy

Vertical partitioning of CO2 production in a forest soil

Patrick Wordell-Dietrich, Anja Wotte, Janet Rethemeyer, Jörg Bachmann, Mirjam Helfrich, Kristina Kirfel, Christoph Leuschner, Axel Don
2020 Biogeosciences  
All raw data (without 14 C) can be accessed in a data package via https://doi.org/10.25532/OPARA-101 (Wordell-Dietrich, 2020). Supplement.  ...  Wordell-Dietrich et al.: Vertical partitioning of CO 2 production in a forest soil https://doi.org/10.5194/bg-17-6341-2020Biogeosciences, 17, 6341-6356, 2020  ... 
doi:10.5194/bg-17-6341-2020 fatcat:ja2djhugdvhflfcgx6dx7en4ty

Influence of tides and tidal current on Mertz Glacier, Antarctica

Benoît Legrésy, Anja Wendt, Ignazio Tabacco, Frédérique Rémy, Reinhard Dietrich
2004 Journal of Glaciology  
Mertz Glacier, East Antarctica, is characterized by a 140 km long, 25 km wide floating ice tongue. In this paper, we combine a large number of remotely sensed datasets, including in situ global positioning system measurements, satellite radar altimetry, airborne radio-echo sounding and satellite synthetic aperture radar imagery and interferometry. These various datasets allow us to study the interaction of the ice tongue with the tides and currents. However, the inverse barometer effect needs
more » ... be applied to sea-level variations affecting the tongue. We find that the tide-induced currents exert a small lateral pressure on the tongue which, when integrated over the large surface of the tongue, induce a flexure of up to 2 m amplitude per day. Simple elastic modelling of the flexure confirms the observations and helps validate the boundary conditions necessary to explain different eastward and westward tongue deflections. In addition, the along-flow velocity of the tongue does vary daily from 1.9 to 6.8 md-1 depending on the tidal current. When the current pushes the tongue toward the eastern boundary of the fjord, the tongue is retarded by the drag and the velocity decreases. The accumulated stress is released, allowing the tongue to flow very rapidly when the current pushes the tongue westward. These forcing and boundary conditions on the floating ice flow are important and must be taken into account when studying glacier discharge and calving.
doi:10.3189/172756504781829828 fatcat:4g6h7j3i2ncybfvbgi5rmzm3u4

Durotropic growth of pollen tubes

Ronny Reimann, Delf Kah, Christoph Mark, Jan Dettmer, Theresa Maria Reimann, Richard Carl Gerum, Anja Geitmann, Ben Fabry, Petra Dietrich, Benedikt Kost
2020 Plant Physiology  
To reach the female gametophyte, growing pollen tubes must penetrate different tissues within the pistil, the female reproductive organ of a flower. Past research has identified various chemotropic cues that guide pollen tubes through the transmitting tract of the pistil, which represents the longest segment of its growth path. In addition, physical mechanisms also play a role in pollen tube guidance; however, these processes remain poorly understood. Here we show that pollen tubes from plants
more » ... ith solid transmitting tracts actively respond to the stiffness of the environment. We found that pollen tubes from Nicotiana tabacum and other plant species with a solid or semi-solid transmitting tract increase their growth rate in response to an increasing matrix stiffness. By contrast, pollen tubes from Lilium longiflorum and other plant species with a hollow transmitting tract decrease their growth rate with increasing matrix stiffness, even though the forces needed to maintain a constant growth rate remain far below the maximum penetration force these pollen tubes are able to generate. Moreover, when confronted with a transition from a softer to a stiffer matrix, pollen tubes from N. tabacum display a greater ability to penetrate into a stiffer matrix compared to pollen tubes from L. longiflorum, even though the maximum force generated by pollen tubes from N. tabacum (11 µN) is smaller than the maximum force generated by pollen tubes from L. longiflorum (36 µN). These findings demonstrate a mechano-sensitive growth behavior, termed here durotropic growth, that is only expressed in pollen tubes from plants with a solid or semi-solid transmitting tract and thus may contribute to an effective pollen tube guidance within the pistil.
doi:10.1104/pp.19.01505 pmid:32241878 pmcid:PMC7271775 fatcat:y2u432jdrjbsni44hxwxkzjcma

An efficient and pragmatic approach for regulatory aquatic mixture risk assessment of pesticides

Christian Dietrich, Magnus Wang, Markus Ebeling, Anja Gladbach
2022 Environmental Sciences Europe  
AbstractThe current regulatory approach to address aquatic mixture toxicity for pesticides in the EU (EFSA J 11:3290, 2013) is rather complex: in typical cases it requires conducting the entire mixture risk assessment scheme for every exposure scenario separately (e.g. 6–8 ecotoxicological endpoints, for each of the nine exposure scenarios for the European Central Zone with 24 common mitigation measure combinations result in over 1700 sub-scenarios to be assessed). This article discusses the
more » ... ilable concepts for a mixture toxicity assessment, the key questions raised and the implementation of these questions in existing risk assessment approaches. Based on this, an alternative, more efficient assessment scheme for aquatic mixture risk assessment (AMiRA) is proposed with the aim of facilitating the practical conduct and interpretation of the assessment while addressing the key questions and preserving the level of protection. The scheme assesses product risk (including a check for non-additive effects), the presence of a risk driver and gains efficiency by the straightforward use of risk quotients (RQ) to calculate mixture risk quotients (RQmix) that are equivalent to the calculation of exposure toxicity ratios for a mixture (ETRmix,CA = Exposure-Toxicity-Ratio for mixtures based on concentration addition) proposed by EFSA (EFSA J 11:3290, 2013). A case study is provided underlining the equivalence of the proposed approach to the EFSA (EFSA J 11:3290, 2013) decision tree.
doi:10.1186/s12302-022-00594-3 fatcat:fweq3fnpincmnndzx5cyx6zwzi

Technologies Turning Future Brick-and-Mortar Stores into Data-Rich Environments

Fabian Buder, Anja Dieckmann, Holger Dietrich, Julia Wieting
2019 NIM Marketing Intelligence Review  
doi:10.2478/nimmir-2019-0008 fatcat:pdqqhap75bformgwem5qmg4mjm

Slave to habit? Obesity is associated with decreased behavioural sensitivity to reward devaluation

Annette Horstmann, Anja Dietrich, David Mathar, Maria Pössel, Arno Villringer, Jane Neumann
2015 Appetite  
1 Horstmann A, Dietrich A, Mathar D, Pössel M, Villringer A, Neumann J. Slave to habit? Obesity is associated with decreased behavioural sensitivity to reward devaluation. Appetite. 2015;87:175-83.  ... 
doi:10.1016/j.appet.2014.12.212 pmid:25543077 fatcat:w3dbbqxobrh75axsfnffczlb6e

Body weight status, eating behavior, sensitivity to reward/punishment, and gender: relationships and interdependencies

Anja Dietrich, Martin Federbusch, Claudia Grellmann, Arno Villringer, Annette Horstmann
2014 Frontiers in Psychology  
Anja Dietrich is funded by a research grant from the Konrad Adenauer Foundation (www.kas.de). The questionnaire contains three subscales.  ... 
doi:10.3389/fpsyg.2014.01073 pmid:25368586 pmcid:PMC4202791 fatcat:gkxloaqjujb7llep7koewdcyfm
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