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A New Fire Resistant Light Mineral Wool

Andrea Frangi, Vanessa Schleifer, Erich Hugi
2011 Fire technology  
Results of fire tests confirm the better performance of stone wool than glass wool * Correspondence should be addressed to: Andrea Frangi, E-mail: frangi@ibk.baug.ethz.ch Fire Technology, 48, 733-752,  ... 
doi:10.1007/s10694-010-0209-2 fatcat:r6afiuczcjettev23bvfrcqw4y

Experimental and Numerical Analysis of Gypsum Plasterboards in Fire

Andrea Frangi, Vanessa Schleifer, Mario Fontana, Erich Hugi
2009 Fire technology  
The fire performance of light timber frame assemblies mainly depends on the protection provided by the cladding. A comprehensive experimental and numerical analysis on the fire behaviour of protective cladding made of gypsum plasterboards and wood-based panels has been recently carried out at ETH Zurich. The paper describes the main results of the experimental and numerical analyses carried out with gypsum plasterboards. The results of the experimental and numerical analysis allowed the
more » ... ent of a design model for the verification of the separating function (insulation and integrity criteria) of light timber frame wall-and-floor assemblies.
doi:10.1007/s10694-009-0097-5 fatcat:hbqoszexsffgnb5ppnv2dztlpq

Visual query system for analyzing social semantic web

Jinghua Groppe, Sven Groppe, Andreas Schleifer
2011 Proceedings of the 20th international conference companion on World wide web - WWW '11  
The social web is becoming increasingly popular and important, because it creates the collective intelligence, which can produce more value than the sum of individuals. The social web uses the Semantic Web technology RDF to describe the social data in a machine-readable way. RDF query languages play certainly an important role in the social data analysis for extracting the collective intelligence. However, constructing such queries is not trivial since the social data is often quite large and
more » ... sembled from a large number of different sources. In order to solve these challenges, we develop a Visual Query System (VQS) for helping the analysts of social data and other semantic data to formulate such queries easily and exactly. In this VQS, we suggest a condensed data view, a browser-like query creation system for absolute beginners and a Visual Query Language (VQL) for beginners and experienced users. Using the browser-like query creation or the VQL, the analysts of social data and other semantic data can construct queries with no or little syntax knowledge; using the condensed view, they can determine easily what queries should to be used. Furthermore, our system also supports precise suggestions to extend and refine existing queries.
doi:10.1145/1963192.1963293 dblp:conf/www/GroppeGS11 fatcat:x5wqzcfv4rhvloavbb4aukmzuq

Rapid identification ofEscherichia colisafety and laboratory strain lineages based on Multiplex-PCR

Andreas Peter Bauer, Sarah Maria Dieckmann, Wolfgang Ludwig, Karl-Heinz Schleifer
2007 FEMS Microbiology Letters  
Escherichia coli K-12, B, C and W strains are the most frequently used bacterial safety and laboratory strains. Lineage-specific DNA fragments were detected by microplate subtractive hybridization and utilized to create a fast differentiation method using a single PCR reaction to differentiate clearly the four lineages and separate them from pathogenic variants. The method has been evaluated on a comprehensive selection of widely used laboratory strains and a variety of pathogenic E. coli
more » ... entatives. In addition, in silico analysis on all available E. coli genomes and the genomes of the close relatives Shigella and Salmonella confirmed the reliability of the proposed method. A fast identification and differentiation of E. coli safety strains by Multiplex-PCR is a useful tool for researchers and companies to check and monitor their reference stocks.
doi:10.1111/j.1574-6968.2006.00594.x pmid:17343689 fatcat:zgbqygkztffmbiguw3vjrn3mvu

KnowTox: pipeline and case study for confident prediction of potential toxic effects of compounds in early phases of development

Andrea Morger, Miriam Mathea, Janosch H. Achenbach, Antje Wolf, Roland Buesen, Klaus-Juergen Schleifer, Robert Landsiedel, Andrea Volkamer
2020 Journal of Cheminformatics  
AM and AV thank Fredrik Svensson, Ulf Norinder, and Andreas Bender for helpful discussions about conformal prediction.  ...  Furthermore, the authors thank Changge Ji and Andreas Bender for sharing the list of toxic alerts from their eMolTox webserver.  ... 
doi:10.1186/s13321-020-00422-x pmid:33431007 pmcid:PMC7157991 fatcat:ql4bsnymizathkxltmpqkngw5a

Nucleic acid-based, cultivation-independent detection ofListeriaspp. and genotypes ofL. monocytogenes

Michael Schmid, Marion Walcher, Andreas Bubert, Martin Wagner, Michael Wagner, Karl-Heinz Schleifer
2003 FEMS Immunology & Medical Microbiology  
Based on comparative analysis of 16S rRNA gene sequences, two oligonucleotide probes for in situ detection of all members of the genus Listeria were designed. These probes allowed fast and reliable in situ detection of Listeria spp. even in complex samples like raw milk. Almost full-length iap (invasion-associated protein) gene sequences were determined for 69 Listeria monocytogenes strains of all 13 known serotypes. A comparison of these sequences revealed that the L. monocytogenes strains can
more » ... be grouped into three distinct genotypes. These clusters correlate well with distinct serotypes. Thus, strains of serotypes b and d belong to genotype I, a and c to genotype II, and 4a and 4c, which are rarely isolated from humans, group together within genotype III. These results could be corroborated by further comparative sequence analysis of genes encoding two phospholipases^plcA and plcB. Based on the iap gene sequences, a highly specific and reproducible competitive PCR detection method was developed. Primer pairs targeting genotype-specific regions of the iap gene were designed. The amplification of non-specific PCR products from DNA of non-target strains was prevented by adding competitive primers. By applying this method, the rapid and reliable distinction of the three L. monocytogenes genotypes was possible.
doi:10.1016/s0928-8244(02)00456-x pmid:12648840 fatcat:yzdria27wvfwldyyqos6xaymg4

In situ detection of a virulence factor mRNA and 16S rRNA inListeria monocytogenes

Michael Wagner, Michael Schmid, Stefan Juretschko, Karl-Heinz Trebesius, Andreas Bubert, Werner Goebel, Karl-Heinz Schleifer
1998 FEMS Microbiology Letters  
Simultaneous in situ analysis of the structure and function of bacterial cells present within complex communities is a key for improving our understanding of microbial ecology. A protocol for the in situ identification of Listeria spp. using fluorescently tagged, rRNA-targeted oligonucleotide probes was developed. Ethanol fixation and enzymatic pretreatment with lysozyme and proteinase K were used to optimize whole cell hybridization of exponential phase and stationary phase Listeria spp.
more » ... In parallel, transcript probes carrying multiple digoxigenin molecules were combined with anti-digoxigenin Fab antibody fragments labeled with horseradish peroxidase to detect, via the catalytic deposition of fluorescein-tyramide, the iap-mRNA in single Listeria monocytogenes cells. The iap gene encodes the associated virulence factor p60. Application of the new signal amplification technique resulted in strong signals comparable in intensity to those obtained with fluorescently labeled rRNAtargeted oligonucleotide probes. z 1998 Federation of European Microbiological Societies. Published by Elsevier Science B.V.
doi:10.1111/j.1574-6968.1998.tb12906.x pmid:9495027 fatcat:kzbwf266tnhltliheyuoyium7e

Relationship between benzodiazepine prescription, aggressive behavior, and behavioral disinhibition: a retrospective study in a Swiss prison

Stéphanie Baggio, Vladan Starcevic, Patrick Heller, Karen Brändle, Irina Franke, Andreas Schneeberger, Anna Buadze, Alex Gamma, Roman Schleifer, Laurent Gétaz, Hans Wolff, Michael Liebrenz
2021 Harm Reduction Journal  
Benzodiazepines are commonly prescribed in prisons amidst the controversies surrounding their potential role in causing behavioral disinhibition and aggressive behavior and their association with use and trafficking of illicit and addictive substances. The present study aimed to (1) ascertain the relationship between benzodiazepine prescription (including their dosage and duration of use) and aggressive behavior and behavioral disinhibition in prison and (2) investigate whether there was an
more » ... ciation between benzodiazepine prescription, (including their dosage and duration of use) and using and trafficking illicit and addictive substances during imprisonment. Data were extracted from the electronic database of an "open" Swiss prison (n = 1206, 1379 measures) over a 5-year period (2010-2015). Measures included benzodiazepine prescription, duration of benzodiazepine use and mean dosage, and punishable behaviors (physical and verbal aggression, disinhibited but not directly aggressive behaviors, property damage or theft, substance-related offenses, and rule transgression). We assessed the relationship between benzodiazepine prescription and punishable behaviors after propensity score matching. Logistic regressions were also used to test the relationship of benzodiazepine use duration and dosage with punishable behaviors among participants who received benzodiazepines. After propensity score matching, benzodiazepine prescription was not significantly associated with any punishable behavior. Among detained persons who took benzodiazepines, there was no significant association of dosage and duration of use with offenses involving illicit or addictive substance use or trafficking. Our study did not empirically support the occurrence of increased aggressive or disinhibited behaviors or increased risk of substance abuse in detained persons who received benzodiazepines in prison. This suggests a need to reconsider restrictions in prescribing benzodiazepines in the prison setting.
doi:10.1186/s12954-021-00504-5 pmid:34016128 fatcat:tshp4aso2rhbhozmlor5wz5xza

Characterization of bacterial operons consisting of two tubulins and a kinesin-like gene by the novel Two-Step Gene Walking method

Martin Pilhofer, Andreas Peter Bauer, Martina Schrallhammer, Lothar Richter, Wolfgang Ludwig, Karl-Heinz Schleifer, Giulio Petroni
2007 Nucleic Acids Research  
doi:10.1093/nar/gkm836 pmid:17942428 pmcid:PMC2175320 fatcat:etnbfrfv2bhctisnl6fxdyj66y

Geophysical Application of the Induced-Polarization(IP)-Effect for the Detection of Medieval Wells

Norbert Schleifer, Jürgen Bigalke, M. Koetter, Andreas Junge, ICOMOS – Hefte Des Deutschen Nationalkomitees
2015
Besides the well-established groundspecific parameters, magnetic susceptibility and apparent resistivity, the polarizability of the soil is another possible parameter for archaeological problems. The induced polarization (IP) bases on electrochemical processes in the subsoil that take place while an electrical current is injected into the ground. Consequently the resulting potential field at the surface is frequency dependent and reflects additional electrical properties of the soil. So far the
more » ... method has been successfully applied for the monitoring of groundwater contamination and the distinction between clay and water-bearing rocks. An application within the archaeological environment could be the detection of medieval wells containing wooden remains for subsequent dendrochronological investigations.
doi:10.11588/ih.1999.0.21963 fatcat:cy4vabdot5bdjohkzfzdakw36y

KnowTox: pipeline and case study for confident prediction of potential toxic effects of compounds in early phases of development

Andrea Morger, Miriam Mathea, Janosch H. Achenbach, Antje Wolf, Roland Buesen, Klaus-Juergen Schleifer, Robert Landsiedel, Andrea Volkamer, Universitätsbibliothek Der FU Berlin
2020
AM and AV thank Fredrik Svensson, Ulf Norinder, and Andreas Bender for helpful discussions about conformal prediction.  ...  Furthermore, the authors thank Changge Ji and Andreas Bender for sharing the list of toxic alerts from their eMolTox webserver.  ... 
doi:10.17169/refubium-27608 fatcat:zdvb6urm7badpgvkgl6oziokhq

Page 27 of The Decalogue Journal Vol. 35, Issue 1 [page]

1992 The Decalogue Journal  
EUGENE LICHTENSTEIN—PAST PRESIDENT, IRV KUPCINET AND ANDREA M. SCHLEIFER January 1992 ~ THE DECALOGUE JOURNAL ~ Page 27  ... 

Page 27 of The Decalogue Journal Vol. 35, Issue 1 [page]

1992 The Decalogue Journal  
EUGENE LICHTENSTEIN—PAST PRESIDENT, IRV KUPCINET AND ANDREA M. SCHLEIFER January 1992 ~ THE DECALOGUE JOURNAL ~ Page 27  ... 

The Effect of Changing the Salinity of the Groundwater on SIP of Sandstones

Andreas Weller, Julian B. T. Scott, Norbert Schleifer, Ron D. Barker
2005 Symposium on the Application of Geophysics to Engineering and Environmental Problems 2005   unpublished
Previous work between the University of Birmingham and Technical University Clausthal examined the basic shape of the complex conductivity spectra of sandstones saturated with a synthetic groundwater solution and compared the two different laboratory measurement procedures. It is known that the Spectral Induced Polarisation (SIP) is also dependent upon the pore fluid so we examined the effect of two different salinity groundwaters on the SIP response. The changes caused by decreasing the
more » ... y of the groundwater varied widely for different sandstones with both increasing and decreasing phase angles recorded along with some changes in the shape of the spectra. We are now continuing to make multiple salinity measurements with a variety of cations in order to better quantify these changes.
doi:10.4133/1.2923428 fatcat:wtrkto2azzgzboqydc7q7o2gbi

Relationship Between Benzodiazepine Prescription, Aggressive Behavior, and Behavioral Disinhibition: A Case-control Study in a Swiss Prison

Stéphanie Baggio, Vladan Starcevic, Patrick Heller, Karen Brändle, Irina Franke, Andreas Schneeberger, Anna Buadze, Roman Schleifer, Alex Gamma, Laurent Gétaz, Hans Wolff, Michael Liebrenz
2020
Background. Benzodiazepines are commonly prescribed in prisons amidst the controversies surrounding their potential role in causing behavioral disinhibition and aggressive behavior and their association with use and tra cking of illicit and addictive substances. The present study aimed to 1) ascertain the relationship between benzodiazepine prescription (including their dosage and duration of use) and aggressive behavior and behavioral disinhibition in prison, and 2) investigate whether there
more » ... s an association between benzodiazepine prescription, (including their dosage and duration of use) and using and tra cking illicit and addictive substances during imprisonment. Methods. Data were extracted from the electronic database of an "open" Swiss prison (n = 1,379) over a ve-year period (2010)(2011)(2012)(2013)(2014)(2015). Measures included benzodiazepine prescription (yes/no), duration of benzodiazepine use and mean dosage, and punishable behaviors (physical and verbal aggression, disinhibited but not directly aggressive behaviors, property damage or theft, substance-related offenses, and rule transgression). Propensity score matching was used to assess the relationship between benzodiazepine prescription and punishable behaviors. Logistic regressions were used to test the relationship of benzodiazepine duration and dosage with punishable behaviors. Results. Benzodiazepine prescription (yes/no) was not signi cantly associated with punishable behaviors. Detained persons taking benzodiazepines were not more likely to commit offenses involving illicit or addictive substance use or tra cking, even when taking these medications in higher dosage and over a longer period of time. Conclusions. Our ndings suggest that access to benzodiazepines in the prison setting should be subject to the same regulations as in the community and that prescribing benzodiazepines to detained persons is just as safe as prescribing these medications to those who are not detained.
doi:10.7892/boris.147801 fatcat:6opora6zqzbdlh3qggsopgfrpu
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