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Telemonitoring of Capillary Blood Flow in the Human Skin: New Opportunities and Prospects

Fedorovich AA, Drapkina OM, Pronko KN, Sinopalnikov VI, Zemskov VM
2018 Clinical Practice  
A conceptually new method for assessing skin microcirculation reviewed here is based on the analysis of video fragments of capillary blood flow in the skin registered with a conventional web camera (smartphone  ...  The method makes it possible to evaluate the character of blood flow on the opposite to the heart "pole" of the greater (systemic) circulation -in the transitional part of the capillaries.  ...  The method is based on the analysis of changes in the contrast of pixels depending on the intensity of blood flow in the capillaries of the skin.  ... 
doi:10.4172/clinical-practice.1000390 fatcat:m76wonndfffvjektjtntzohu3y

An association between vasomotion and oxygen extraction

Clare E. Thorn, Hayley Kyte, Dick W. Slaff, Angela C. Shore
2011 American Journal of Physiology. Heart and Circulatory Physiology  
The effect of fluctuation in blood pressure approximately every 10 s, known as Mayer waves, can be observed in tissue as a 0.1-Hz oscillation in blood volume and flow (3, 23, 57).  ...  Fourier analysis identified periodic fluctuations in S mbO2 in 19 out of 24 subjects, predominantly where skin temperatures were Ͼ29.3°C (X 2 ϭ 6.19, P Ͻ 0.02).  ...  DISCLOSURES The opinions given in this paper do not necessarily represent those of NIHR, the NHS or the Department of Health.  ... 
doi:10.1152/ajpheart.01316.2010 pmid:21602466 pmcid:PMC3154677 fatcat:znebcsikejeivni6dv2fmqvnhm

Evaluation of the microcirculation in vascular disease

Christopher J. Abularrage, Anton N. Sidawy, Gilbert Aidinian, Niten Singh, Jonathan M. Weiswasser, Subodh Arora
2005 Journal of Vascular Surgery  
Dysfunction of the microcirculation occurs in a similar fashion in multiple tissue beds long before the onset of atherosclerotic symptoms.  ...  We discuss the importance of the microcirculation, investigative methods for evaluating its function, and clinical applications and review the literature of the microcirculation in these different states  ...  By subtracting the flow in the 133 Xe washout method from that of the heat washout method, one can determine the contribution of blood flow from AV shunts in glabrous skin. Vasoreactivity.  ... 
doi:10.1016/j.jvs.2005.05.019 pmid:16171612 fatcat:2x7bekjkvve3dlm5wxkc6kln6y

Direct Evidence for Insulin-Induced Capillary Recruitment in Skin of Healthy Subjects During Physiological Hyperinsulinemia

E. H. Serne, R. G. IJzerman, R. O.B. Gans, R. Nijveldt, G. de Vries, R. Evertz, A. J.M. Donker, C. D.A. Stehouwer
2002 Diabetes  
In addition, the effects of locally administered insulin on skin blood flow were assessed in 10 healthy subjects.  ...  However, the putative effects of insulin on the microcirculation that permit such modulation have not been studied in humans.  ...  (the Netherlands) is kindly acknowledged for providing the diluting medium for soluble insulin injection. The authors thank Renate de Jongh for her excellent assistance.  ... 
doi:10.2337/diabetes.51.5.1515 pmid:11978650 fatcat:fdppmkp3gjgsna5vmzcqykeimm

Erythrocyte Velocity and a Velocity Pulse in Minute Blood Vessels on the Surface of the Mouse Brain

WILLIAM I. ROSENBLUM
1969 Circulation Research  
ADDITIONAL KEY WORDS high speed microcinematography cerebral microcirculation pulsatile flow  ...  The frequency of the velocity pulse was virtually identical to that of the peripheral pulse and is believed to result from a propagation of that pulse into the microcirculation.  ...  MEASUREMENT OF VELOCITY PULSE Although textural details in the center of the blood stream were too obscure on the film to permit tracking of cells, one could readily observe that the column of blood was  ... 
doi:10.1161/01.res.24.6.887 pmid:5786793 fatcat:l6sbwk7znzdrdcqhwar6p2sz7i

The Markers of Endothelial Activation [chapter]

Ines Drenjancevic, Ivana Jukic, Ana Stupin, Anita Cosic, Marko Stupin, Kristina Selthofer-Relatic
2018 Endothelial Dysfunction - Old Concepts and New Challenges  
One very important question is how specific and sensitive the marker is, since one molecule can appear in many conditions.  ...  This chapter aims to overview current knowledge on established biomarkers of normal and disease-related endothelial activation and to provide information on novel, potential biomarkers in common cardiometabolic  ...  Another cuff excludes the blood flow through the hand to reduce the temperature fluctuations of the blood flow depending on the temperature.  ... 
doi:10.5772/intechopen.74671 fatcat:fsh4vjbmknbkvkr74vrnvk5fum

Wavelet-analysis of gastric microcirculation in rats with ulcer bleedings

A.N. Pavlov, O.V. Semyachkina-Glushkovskaya, O.N. Pavlova, O.A. Bibikova, J. Kurths
2013 The European Physical Journal Special Topics  
Numerical analysis of LDF-data is based on the discrete wavelet-transform (DWT) using Daubechies wavelets aiming to quantify influences of NO on the gastric microcirculation.  ...  blood flow.  ...  This work was supported by the Russian Foundation for Basic Research (grants 11-02-00560-a, 12-02-31204) and by the RF Ministry of Education and Sciences within the  ... 
doi:10.1140/epjst/e2013-02050-7 fatcat:wfzgr645kbd2rglkluf7xo5s2q

Simple and non-invasive techniques to evaluate the function of CircuLite Synergy

Prashant N. Mohite, Christopher T. Bowles, Anton Sabashnikov, Aron-Frederik Popov, Nikhil P. Patil, Diana García Sáez, Nicholas R. Banner, André R. Simon
2014 Interactive Cardiovascular and Thoracic Surgery  
The aim of this study was to develop a simple non-invasive monitoring technique to assess pump function based on the detection of the ASA in the peripheral microcirculation.  ...  the blood flow behaviour, thereby reducing thrombogenicity.  ...  Conflict of interest: none declared.  ... 
doi:10.1093/icvts/ivu236 pmid:25085860 fatcat:axen2olimzhaffg7d3cut3ubze

Central, peripheral and resistance arterial reactivity: fluctuates during the phases of the menstrual cycle

Eric J Adkisson, Darren P Casey, Darren T Beck, Alvaro N Gurovich, Jeffery S Martin, Randy W Braith
2010 Experimental biology and medicine  
Peak forearm and calf blood flow during reactive hyperemia were greatest in LF. Brachial FMD was greatest during the LF phase (P < 0.05).  ...  Measurement of peripheral endothelial function was determined by flow-mediated dilation (FMD) testing in the brachial artery and venous occlusion plethysmography in the forearm and calf resistance arteries  ...  In an attempt to measure the endothelial-dependent reactivity of the microcirculation, we occluded blood flow for 5 min using a cuff inflated to 200 mmHg and positioned proximal to the anticubital fossa  ... 
doi:10.1258/ebm.2009.009186 pmid:20404025 pmcid:PMC2967291 fatcat:7dic72tnzrhxreb6b3okrxjd7q

Arterial functions: how to interpret the complex physiology

G. M. London, B. Pannier
2010 Nephrology, Dialysis and Transplantation  
Analysis of aortic or carotid pressure waveform and amplitude concerns the effect of reflected waves on pressure shape and amplitude, estimated in absolute terms, augmented pressure in millimetre of mercury  ...  Peripheral resistance as a determinant of mean BP sets the general level at which the pressure wave will fluctuate, and represents the opposition to steady component of blood flow, i.e. cardiac output.  ...  Peripheral resistance as a determinant of mean BP sets the general level at which the pressure wave will fluctuate, and represents the opposition to steady component of blood flow, i.e. cardiac output.  ... 
doi:10.1093/ndt/gfq614 pmid:20947536 fatcat:lpkcfkify5a5hdnv3qkipbbfti

The role of perfusion in the oxygen extraction capability of skin and skeletal muscle

Clare E. Thorn, Angela C. Shore
2016 American Journal of Physiology. Heart and Circulatory Physiology  
). 36 The classic model of metabolic blood flow regulation to support oxygen extraction is evident in perfused skin; 37 OE is perturbed without blood flow and reduced in obesity.  ...  Firstly, from the rate of fall in mean blood saturation during a 4 minute below knee 29 arterial occlusion, and thus no blood flow, in calf skin and skeletal muscle.  ...  This leads to 59 a cyclical behaviour fluctuating between normoxic and hypoxic states.  ... 
doi:10.1152/ajpheart.00047.2016 pmid:27016577 pmcid:PMC4895834 fatcat:xx77445bkvajldjbidmzb6yio4

Microcirculation and Hyperbaric Oxygen Treatment [chapter]

Fethi Gul, Omer Faruk Boran, Reyhan Arslantas
2018 Hyperbaric Oxygen Treatment in Research and Clinical Practice - Mechanisms of Action in Focus  
This delicate balance can play an important role in the progression of critical illnesses and has a role in the development of organ dysfunction.  ...  In this chapter, we aim to describe microcirculation with its monitoring systems and to show the effectiveness of HBOT in different clinical settings, which are related to microcirculatory dysfunction.  ...  During hyperoxia the reactive oxygen radicals prevent nitric oxide-mediated vasodilatation; on the other hand, vascoconstrictor effect results in low tissue blood flow [27] .  ... 
doi:10.5772/intechopen.75609 fatcat:iuiweyczjbbqfow3igzbyexirq

The capillary bed offers the largest hemodynamic resistance to the cortical blood supply

Ian Gopal Gould, Philbert Tsai, David Kleinfeld, Andreas Linninger
2016 Journal of Cerebral Blood Flow and Metabolism  
Difficulties in imaging the complex microanatomy of the cortex have so far restricted insight about blood flow distribution in the microcirculation.  ...  The cortical angioarchitecture is a key factor in controlling cerebral blood flow and oxygen metabolism.  ...  The authors disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The authors would like to acknowledge the National Science Foundation  ... 
doi:10.1177/0271678x16671146 pmid:27780904 pmcid:PMC5363755 fatcat:7zr32p6xbreqrlln3ki65zxpe4

Quantification of myocardial blood flow with cardiovascular magnetic resonance throughout the cardiac cycle

Manish Motwani, Ananth Kidambi, Akhlaque Uddin, Steven Sourbron, John P Greenwood, Sven Plein
2015 Journal of Cardiovascular Magnetic Resonance  
Myocardial blood flow (MBF) varies throughout the cardiac cycle in response to phasic changes in myocardial tension.  ...  This technique may be useful in future pathophysiological studies of coronary blood flow and microvascular function.  ...  Background Myocardial blood flow (MBF) varies throughout the cardiac cycle in response to changes in myocardial tension and phasic compression of the myocardial microcirculation [1] [2] [3] [4] .  ... 
doi:10.1186/s12968-015-0107-3 pmid:25630861 pmcid:PMC4308908 fatcat:daoo7kurkrczdk7xm7eu2inqae

Diurnal variation in uterine artery blood flow in post-menopausal women on oestrogen hormone replacement therapy

D. Jurkovic, D. Ross, N. Aslam, M. Whitehead
1999 Human Reproduction  
The assessment of uterine artery blood flow in post-menopausal women should take into account the presence of circadian variations to ensure accuracy and reproducibility of Doppler investigations.  ...  Doppler ultrasound was used to investigate circadian variations in uterine artery blood flow in 20 post-menopausal women in the oestrogen-only phase of combined oestrogen hormone replacement therapy with  ...  The average increase in the impedance to flow was 13% which is much less than circadian fluctuations observed in our study.  ... 
doi:10.1093/humrep/14.11.2716 pmid:10548607 fatcat:bouiiyfoffcxjhppav246imzny
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