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Economic Evaluation of a Universal Childhood Pneumococcal Conjugate Vaccination Strategy in Ireland
2008
Value in Health
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of the herd immunity effect. ...
In a separate submodel, the effect of herd immunity was investigated. ...
[7] , using administrative data, have provided further evidence of the herd immunity effect from routine pneumococcal vaccination of children and infants, where a reduction in hospitalized [11] Reduction ...
doi:10.1111/j.1524-4733.2008.00341.x
pmid:18489504
fatcat:4ilf4ktd4fanteqytxqx44kcga
Impact of vaccination on the COVID-19 pandemic: Evidence from U.S. states
[article]
2021
medRxiv
pre-print
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In this study, we evaluated the effectiveness of the COVID-19 vaccination program and predicted the path to herd immunity in the U.S. ...
Using data from 12 October 2020 to 7 March 2021, we estimated that vaccination reduced the total number of new cases by 4.4 million (from 33.0 to 28.6 million), prevented approximately 0.12 million hospitalizations ...
Warner and S. Mennemeyer for their feedback. Funding: H.H. is supported by the startup grant from the City University of Hong Kong (grant no. 7200689). ...
doi:10.1101/2021.05.08.21256892
fatcat:r2u2qcri6bcqdhbyl355vxrgh4
A review of economic evaluations of 13-valent pneumococcal conjugate vaccine (PCV13) in adults and the elderly
2015
Human Vaccines & Immunotherapeutics
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Key uncertainties included the efficacy of PCV13 against non-invasive pneumonia and the herd immunity effect of childhood vaccination programs. ...
The 13-valent pneumococcal conjugated vaccine (PCV13) is already recommended for some adult groups and is being considered for wider use in many countries. ...
against IPD and NPP, the effectiveness of PPV23 used to estimate the "no vaccination" baseline and the assumed herd immunity of PCV13 immunization in infants. ...
doi:10.1080/21645515.2015.1011954
pmid:25933180
pmcid:PMC4514194
fatcat:2ild3hgs25c4thadcmnys4hl7a
Streamlined Analysis for Evaluating the Use of Preharvest Interventions Intended to Prevent Escherichia coli O157:H7 Illness in Humans
2009
Foodborne pathogens and disease
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The production functions are then used for marginal economic analysis to assess the cost=benefit ratio of using the vaccine to prevent foodborne illness. ...
A combination of quantitative risk assessment methods and marginal economic analysis are used to describe the maximum cost per unit that would still allow the vaccine to be a cost-effective intervention ...
If decision makers were to consider the use of a real vaccine, the efficacy, required coverage for herd immunity, and cost per vaccinated animal would be known. ...
doi:10.1089/fpd.2008.0255
pmid:19737060
fatcat:uboyv34iu5bjzlob5wgkuy7smy
Attainment of Herd Immunity: Mathematical Modelling of Survival Rate
[article]
2020
arXiv
pre-print
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We study the influence of the rate of the attainment of herd immunity (HI), in the absence of an approved vaccine, on the vulnerable population. ...
Our results quantify the adverse effects on the recovery rates of vulnerables in the course of attaining the herd immunity. ...
The authors thank the Department of Science and Technology (DST), India for financial support. BB thanks sir J. C. Bose fellowship for partial financial support. S. ...
arXiv:2005.14496v1
fatcat:abxvdzkn75esrcdjzu3mn42xz4
Endemic foot and mouth disease: pastoral in-herd disease dynamics in sub-Saharan Africa
2019
Scientific Reports
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We address this knowledge gap using stochastic, compartmental modelling to explore FMD virus (FMDV) persistence, outbreak dynamics and disease burden in individual cattle herds within an endemic setting ...
Our analysis suggests repeated introduction of virus from outside the herd is required for long-term viral persistence, irrespective of carrier presence. ...
Furthermore, varying levels of immunity and greater movement and interaction between herds are generally not relevant in FMD-free settings but need to be considered in endemic settings. ...
doi:10.1038/s41598-019-53658-5
pmid:31757992
pmcid:PMC6874544
fatcat:ay2fc64szfauhkj5iu4tnjz2t4
Optimising Assessments of the Epidemiological Impact in the Netherlands of Paediatric Immunisation with 13-Valent Pneumococcal Conjugate Vaccine Using Dynamic Transmission Modelling
2014
PLoS ONE
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Using available Dutch data, a dynamic transmission model for the spread of pneumococci and potential subsequent invasive pneumococcal disease has been adapted to the Dutch setting. ...
The results are quite robust for the sensitivity analyses performed on the parameters that regulate herd immunity and competition between vaccine and non-vaccine types. ...
Acknowledgments The authors would like to thank Drs Mark Rozenbaum, Albert van Hoek, Yoon Choi, and Raymond Farkouh for very useful discussions and feedback on the topic. ...
doi:10.1371/journal.pone.0089415
pmid:24694656
pmcid:PMC3973563
fatcat:d5g25623rfbddaapmgczwjwhxq
Ebola could be eradicated through voluntary vaccination
2018
Royal Society Open Science
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We found that if a population adopts selfishly optimal vaccination strategies, then the population vaccination coverage falls negligibly short of the herd immunity level. ...
We conducted uncertainty and sensitivity analysis to demonstrate that our findings do not depend on the choice of the epidemiological model parameters. ...
Leshowitz and P. Waiker, who served as graduate assistants during the REU program where this research was conducted, and F. Agusto for sharing her methodology for performing sensitivity analysis. ...
doi:10.1098/rsos.171591
pmid:29410863
pmcid:PMC5792940
fatcat:dp3ynaskdbb6rcc7byqpugzynq
Meningococcal Serogroup A, C, W135 and Y Conjugated Vaccine: A Cost-Effectiveness Analysis in the Netherlands
2013
PLoS ONE
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Despite its success, herd immunity may wane over time. Recently, a serogroup A,C,W135,Y meningococcal conjugate vaccine (MenACWY) was licensed for use in subjects of 12 months of age and above. ...
Methods: A decision analysis cohort model, with 185,000 Dutch newborns, was used to evaluate the cost-effectiveness of different immunization strategies. ...
Because this method uses data on the amount of cases in the population [38] , a part of the herd immunity effect might be included in our VE estimate, possibly leading to an underestimation of the initial ...
doi:10.1371/journal.pone.0065036
pmid:23741448
pmcid:PMC3669019
fatcat:adcx3roiwbbv5afeabgtjazn5m
Inducing Herd Immunity against Seasonal Influenza in Long-Term Care Facilities through Employee Vaccination Coverage: A Transmission Dynamics Model
2015
Computational and Mathematical Methods in Medicine
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We used influenza surveillance data from all LTCFs in New Mexico to validate a transmission dynamics model developed to investigate herd immunity induction.Material and Methods. ...
Vaccinating healthcare workers (HCWs) in long-term care facilities (LTCFs) may effectively induce herd immunity and protect residents against influenza-related morbidity and mortality. ...
Conflict of Interests The authors declare that there is no conflict of interests regarding the publication of this paper. ...
doi:10.1155/2015/178247
pmid:26101542
pmcid:PMC4458543
fatcat:cgr44bgx5zdd7ppptlzwov5xga
Cost-effectiveness of a potential Zika vaccine candidate: a case study for Colombia
2018
BMC Medicine
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Methods: Using an agent-based simulation model of ZIKV transmission dynamics in a Colombian population setting, we conducted cost-effectiveness analysis with and without pre-existing herd immunity. ...
vaccine is cost-saving (with negative incremental cost-effective ratio; ICER) for vaccination costs up to US$6 per individual without herd immunity, and up to US$4 per individual with 8% herd immunity. ...
Availability of data and materials The computational modeling framework used for this study is available at: https://github.com/affans/zika/tree/publication. ...
doi:10.1186/s12916-018-1091-x
pmid:29966516
pmcid:PMC6029035
fatcat:bdd2jb3dfjdffi7bpca44mplcm
Mathematical model of hepatitis B in the Bosomtwe district of Ashanti region, Ghana
2014
Applied Mathematical Sciences
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A combination of increased vaccination of newborns and immunization of susceptible adults appears to reduce HB prevalence in Bosomtwe District to the minimum. ...
We use SIR model to predict the prevalence and incidence of Hepatitis B in Bosomtwe District of Ghana. The study is made up of two sections. ...
Sensitivity Analysis of the Endemic Equilibrium State
The Herd Immunity Threshold The Herd Immunity Threshold (H1) is the percentage of the population that needs to be immune to control transmission ...
doi:10.12988/ams.2014.44263
fatcat:oqgznohkhvcefk7mfdssyh7myi
Vaccine Induced Herd Immunity for Control of Respiratory Syncytial Virus Disease in a Low-Income Country Setting
2015
PLoS ONE
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Development of vaccines for young infants is complicated by the presence of maternal antibodies and immunological immaturity, but vaccines targeted at older children avoid these problems. ...
viral cause of respiratory morbidity and mortality in young children. ...
Acknowledgments The authors acknowledge the contribution of the laboratory, field and data team at KEMRI-Wellcome Research Programme, Kenya. ...
doi:10.1371/journal.pone.0138018
pmid:26390032
pmcid:PMC4577090
fatcat:hgu67l255bhrphbgnjwg4x366a
Sex-Specific Immunization for Sexually Transmitted Infections Such as Human Papillomavirus: Insights from Mathematical Models
2011
PLoS Medicine
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Methods and Findings: We use a range of two-sex transmission models with varying detail to identify general criteria for allocating a prophylactic vaccine between both sexes. ...
Exceptions arise only when the higher prevaccine prevalence is due to a substantially lower rate of natural immunity, or when natural immunity is lifelong, and a prolonged duration of infectiousness coincides ...
of vaccine-preventable disease (herd immunity). ...
doi:10.1371/journal.pmed.1001147
pmid:22205887
pmcid:PMC3243713
fatcat:2kt53dc4xffmxenbzdhtgmsxum
How to Understand "Herd Immunity" in COVID-19 Pandemic
2020
Frontiers in Cell and Developmental Biology
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Different countries are adopting varied response strategy in terms of their public health system to prevent the spread. Herd immunity has been a hot topic since the outbreak of COVID-19 pandemic. ...
immunity, and discuss its feasibility in COVID-19 prevention. ...
ZZ, JL, YC, AZ, LH, and ZL contributed to the acquisition of data for the work. All authors contributed to manuscript revision, read and approved the submitted version. ...
doi:10.3389/fcell.2020.547314
pmid:33072741
pmcid:PMC7543944
fatcat:nacl4x7isrc6dlumwprogvq5em
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