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An efficient and accurate integration of mini-Mu transposons in vitro: a general methodology for functional genetic analysis and molecular biology applications

S. Haapa, S. Taira, E. Heikkinen, H. Savilahti
1999 Nucleic Acids Research  
The Mu methodology is readily applicable in a variety of current and emerging transposon-based techniques and is expected to generate novel approaches to functional analysis of genes, genomes and proteins  ...  The utility of the Mu system in functional genetic analysis is demonstrated using restriction analysis and genetic footprinting strategies.  ...  ACKNOWLEDGEMENTS We thank Arja Lamberg, Alan Schulman and Dik van Gent for critical reading of the manuscript and Lars Paulin for his help in DNA sequence analysis.  ... 
doi:10.1093/nar/27.13.2777 pmid:10373596 pmcid:PMC148488 fatcat:arsizxvjnbagzgxx7dcnr43rc4

A Framework for the Integration of Functional and Non-functional Analysis of Software Architectures

V. Cortellessa, A. Di Marco, P. Inverardi, F. Mancinelli, P. Pelliccione
2005 Electronical Notes in Theoretical Computer Science  
The separation of functional and non-functional analysis of software systems often prevents from considering design solutions that would be evident if an integrated analysis would be possible.  ...  The relations help to automatically propagate the analysis feedback among software models. We specify how different analysis methodologies can be integrated in our framework.  ...  A framework for software analysis integration In Figure 1 we show the architecture of our framework for the integration of functional and non-functional analysis of software architectures.  ... 
doi:10.1016/j.entcs.2004.02.088 fatcat:ctvhmfkfszbfdibpxpcdaxz6cy

System Framework for the Design of an Avionics Architecture with Upgrade Potential

N. Rao, R. Kusumo, A. K. Sinha, M. L. Scott
2002 Acta Polytechnica  
A 'system approach' is adopted to develop a methodology that identifies the design parameters that will facilitate design of an avionics architecture with upgrade potential.  ...  A research program that partially addresses avionics systems upgrade by developing a methodology to design an avionics architecture with in-built growth potential is discussed in this research paper.  ...  An interrelationship analysis of the components and their attributes (functional requirements) provides the methodology to integrate the design parameters of the architecture and advanced avionics systems  ... 
doaj:363405a8dc654296bd4641beb0b1cd4e fatcat:2o6yhqno4zeutjle6yj7golajq

Analysis of Functional Architectures for Discrete Event Logistics Systems (DELS)

Timothy Sprock, Leon F. McGinnis
2015 Procedia Computer Science  
Creating a functional architecture for a new system is as much an art form as a science and often relies on the tacit knowledge of the systems architect.  ...  This method relies on integrating the description of the functional architecture with a formal network description and using that formal network description to provide access to analysis generation technologies  ...  This section introduces an MBSE design and analysis methodology for DELS.  ... 
doi:10.1016/j.procs.2015.03.022 fatcat:u6biuooxcza5pgfprpwqetsueq

The Use of Function Modelling Methods in Industry: Insights from a Large Scale Study with an Automotive OEM

U. Yildirim, F. Campean, A. Uddin
2022 Proceedings of the Design Society  
AbstractThis paper presents an evaluation study for the System State Flow Diagram function modeling framework based on a large-scale study with an automotive OEM.  ...  methodology.  ...  Eisenbart et al. (2015 and also presented an evaluation study for the Integrated Function Modeling framework with practitioners in industry.  ... 
doi:10.1017/pds.2022.69 fatcat:myitf2vv2vdmrlsx3fiu2ax344

A Methodology for the Integration of Service Repositories

Carlo Batini, Marco Comerio
2016 Communications of the IBIMA  
In this paper, we present (i) a model for service description in service repositories and (ii) a methodology for the integration of service repositories guided by the discovery of correspondences between  ...  services in different repositories to be integrated.  ...  ) SPAC3 (Smart services of the new Public Administration for the Citizen-Centricity in the Cloud) co-financed by the Lombardy region  ... 
doi:10.5171/2016.790219 fatcat:3e4takddxzd6nicflzw55bdjyy

An Integrated Framework for Strategic Information Systems Planning and Development

Somendra Pant, Cheng Hsu
1999 Information Resources Management Journal  
Information has emerged as an agent of integration and the enabler of new competitiveness for today's enterprise in the global marketplace.  ...  An integration of strategy with planning and development through enterprise information resources -which capture and characterize the enterprise -will shorten the response cycle for employing and deploying  ...  Integration of the functions will, however, provide for real-time interaction between these functions.  ... 
doi:10.4018/irmj.1999010102 fatcat:lcsa4lpib5dhzig7k5ts43yzt4

A Comparison of Various Software Development Methodologies: Feasibility and Methods of Integration

Samir Abou El-Seoud
2016 International Journal of Recent Contributions from Engineering, Science & IT  
The prototype system has been tested during the development of a software for an ATM "Auto Teller Machine" by selecting and applying SASD methodology during software development.  ...  A prototype system which integrates the selected methodologies has been developed.  ...  The search for perfect methodology which can do all different nature of tasks is a dream or an illusion.  ... 
doi:10.3991/ijes.v4i4.6547 fatcat:ejwtsfeby5gdfeqxmlk4247llq

Software components for reliable automotive systems

H. Heinecke, W. Damm, B. Josko, A. Metzner, H. Kopetz, A. Sangiovanni-Vincentelli, M. Di Natale
2008 Proceedings of the conference on Design, automation and test in Europe - DATE '08  
System-level integration requires an overall understanding of the interplay of the sub-systems to enable componentbased development with portability, reconfigurability and extensibility, together with  ...  Integration by simple interfaces and plugand-play of sub-systems, which is the main objective of AU-TOSAR, requires solving essential technical problems.  ...  of functions and features integrated in a particular vehicle development. • This same separation, however, inherently limits the capabilities for system-level analysis, which strives for an early assessment  ... 
doi:10.1145/1403375.1403508 fatcat:qo4p6ffr2jfrxex4r2xyzxlolq

Software Components for Reliable Automotive Systems

H. Heinecke, W. Damm, B. Josko, A. Metzner, H. Kopetz, A. Sangiovanni-Vincentelli, M. Di Natale
2008 2008 Design, Automation and Test in Europe  
System-level integration requires an overall understanding of the interplay of the sub-systems to enable componentbased development with portability, reconfigurability and extensibility, together with  ...  Integration by simple interfaces and plugand-play of sub-systems, which is the main objective of AU-TOSAR, requires solving essential technical problems.  ...  of functions and features integrated in a particular vehicle development. • This same separation, however, inherently limits the capabilities for system-level analysis, which strives for an early assessment  ... 
doi:10.1109/date.2008.4484733 dblp:conf/date/HeineckeDJMKSN08 fatcat:vam6fiokdrdcvfikukfvfao7cu

New Attitude to Functions Reviews of Public Institutions

Živilė Tunčikienė, Rolandas Drejeris
2015 Journal of Business Law and Ethics  
factors and methodological approaches which are recommended in setting an integrated combination of the methodological approaches for particular situation of public institutions.  ...  Our research allowed to supplement the methodological basis of functions review with well-founded approaches and to systemise methodological provisions for functions review.  ...  of integrated methodology for functions review use.  ... 
doi:10.15640/jble.v3n1a1 fatcat:3fdxdalc5nfblmsfjgzu6hrzm4

Planning for Computer Integrated Construction

Youngsoo Jung, G. Edward Gibson
1999 Journal of computing in civil engineering  
This situation calls for an effective CIC planning methodology, particularly on a company level.  ...  Computer integrated construction (CIC) has recently evolved to maximize the integrated utilization of information systems throughout the project's entire life cycle and across different business functions  ...  Integration Effectiveness Analysis To evaluate the contribution of each business function for entire systems' integration, an integration effectiveness matrix was developed as shown in Fig. 2 .  ... 
doi:10.1061/(asce)0887-3801(1999)13:4(217) fatcat:hu46wsl6wfaznfud3iwn6rjtmq

Using Quality Function Deployment in Singulation Process Analysis

Hang-wai Law, Meng Hua
2007 Engineering Letters  
This paper presents the application of quality function deployment (QFD) to process analysis.  ...  An improved QFD framework is proposed, in which, customer requirements are identified through value engineering and strategic analysis.  ...  Integrated DEFinition (IDEF) methodology is then used for process mapping to systemically formulate the functional characteristics of the product.  ... 
dblp:journals/engl/LawH07 fatcat:dcgznwtb6rgj3pwoq6haey77o4

Semantic integration of gene expression analysis tools and data sources using software connectors

Flávia A Miyazaki, Gabriela DA Guardia, Ricardo ZN Vêncio, Cléver RG de Farias
2013 BMC Genomics  
This work aims at developing an ontology-based methodology for the semantic integration of gene expression analysis tools and data sources.  ...  The study and analysis of gene expression measurements is the primary focus of functional genomics.  ...  Authors' contributions FM defined the methodology, helped to define the reference ontology and to implement the integration scenarios.  ... 
doi:10.1186/1471-2164-14-s6-s2 pmid:24341380 pmcid:PMC3908368 fatcat:6ujasyq5kbhb5nkcsxjtxp5lqi

AN INTEGRATED DESIGN METHODOLOGY

T. Freiheit, S. S. Park, V Giuliani
2011 Proceedings of the Canadian Engineering Education Association (CEEA)  
To de-liver all design requirements, an efficient integrated design methodology is required.  ...  Many tools and design methodolo-gies have been developed that address individual as-pects of the design problem, such as Axiomatic De-sign, Design for Manufacture, Life Cycle Design, etc.  ...  Gu for invaluable discussion of design methodologies.  ... 
doi:10.24908/pceea.v0i0.3925 fatcat:hm2ctt2ldvdhxfc4xbwsfmbqe4
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